Bio-Rad Laboratories AUTOIMMUNE TESTING. System. PhD. IFA and EIA Instrumentation. One revolutionary platform, two technologies

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1 Bio-Rad Laboratories AUTOIMMUNE TESTING IFA and EIA Instrumentation One revolutionary platform, two technologies

2 Bio-Rad Laboratories AUTOIMMUNE TESTING Autoimmune IFA and EIA testing Flexibility, efficiency and accuracy from the worldwide leader in autoimmune testing. The s unique modular design provides laboratories with the ability to efficiently process low to high test volume workloads. One to ten workstations can be controlled by a single computer, providing the flexibility to process IFA slides and EIA microplates simultaneously! The proprietary volumetric pump allows the new to accurately and consistently deliver volumes down to one microliter The combination of robust instrument design and multiple workstation networking provides unparalleled reliability Efficient dual technology IFA and EIA Both technologies on a single instrument Easily switched from one technology to another Uni-directional LIS (IFA) and Bi-directional LIS (EIA) via RS-232 or TCP/IP connection Graphical User Interface for intuitive programming and easy navigation Minimum number of components; minimal maintenance

3 IFA Up to 4 assays per run per workstation Up to 20 slides per run per workstation Up to 96 patients per run per workstation Completely automates front-end processing of slides sample and control dilution, conjugate addition, incubation, slide washing and counterstain preparation and addition Easily accommodates standard 75 x 25 mm slides IFA Slide Rack Kallestad IFA Slides Left Sample Rack IFA Reagent Rack EIA Accurate Proprietary servo-controlled volumetric pump consistently and accurately delivers volumes down to one microliter In well dilution capability eliminates need for off-line dilution of samples allowing direct dilution in the microwells EIA Reagent Rack Up to 192 samples, controls, calibrators per run per workstation Up to 8 compatible assays per run per workstation Reagent rack accommodates up to 8 sets of reagents Network up to 10 workstations to a single computer for parallel processing Right Sample Rack Modular design accommodates small to high volume laboratories Proprietary Volumetric Pump

4 IFA Software Printed Worksheet to record pattern interpretations Integrated slide designer allows slide definition of well positions, surfaces and texts Easy-To-Use Graphical Interface INTEGRATED TEST DESIGNER Integrated Slide Designer Integrated test designer provides ease in defining test steps necessary to process slides for screening and titration testing. It also provides flexible wash parameters for optimal well washing. Flexible dilution ratios for titered samples ranging from undiluted to 1:5120 INTEGRATED TEST DESIGNER EIA Software Graphical template for easy assay setup Flexible programming for user-defined assays including wash options to define: Dispense speed Number of wash cycles Wash volume Residual wash volume after the last wash cycle Easy-To-Use Graphical Interface Bi-directional LIS communication via RS-232 or TCP/IP connection Extensive data analysis regression options offering 4PL, 5PL, Linear Regression, Cubic Spline, Log-Logit and Point-to-Point DATA ANALYSIS REGRESSION OPTIONS

5 AUTOIMMUNE TESTING Instrument Specifications Weight lbs. (91 kg) Dimensions cm deep x cm wide x 88.9 cm high Weight...77 lbs. (35 kg) Dimensions cm deep x cm wide x cm high Power Requirements to 240 volts; 50 to 60 Hz; 65 to 200 watts Pump...Customized ceramic, valveless Self-contained Fluidics...Modular design Probe Positioning...Closed loop Servo-motor feedback system Print record of all transactions Printer Print layout of Deck Data sent in standard ASTM To LIS Personal Computer Ethernet Hub No. 1 No. 6 No. 2 No. 7 No. 3 No. 8 No. 4 No. 9 No. 5 No. 10 Data Reduction and QC files EIA Plate Reader Keyboard Input Patient ID with keyboard or bar code scanner Bar Code Scanner Bar code plates to ID Test and Up to ten PhD s can run consecutively or simultaneously Ordering Information Catalog No. Description Components (for North American customers only) (110V) (includes computer, monitor, printer, reader, bar code scanner, UPS, surge protector and Ethernet hub)... 1 unit EX Components (for customers in Europe and Asia) (220V) (includes Catalog No except for UPS, surge protector and Ethernet hub)... 1 unit with Accessory Pack (for all customers) (110/220V)... 1 unit (for North American customers only) (110V) (includes Catalog No and )... 1 unit EX (for customers in Europe and Asia) (220V) (includes Catalog No EX and )... 1 unit IFA Module (includes PhD IFA software, reagent template, slide holder and starter pack)... 1 unit For further information, please contact the Bio-Rad office nearest you or visit our website at Clinical Diagnostics Group Website U.S BIO-RAD Australia Austria Belgium Brazil Canada China Czech Republic Denmark Finland France Germany +49-(0) Greece Hong Kong Hungary India Israel Italy Japan Korea Mexico +52 (55) The Netherlands New Zealand Norway Poland Portugal Russia Singapore South Africa Spain Sweden Switzerland Thailand United Kingdom +44-(0) Printed on recycled paper with soy-based inks 2011 Bio-Rad Laboratories, Inc. Printed in USA 07/11 DG Q-757

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