REGULATORY COMPLIANCE. Each device complies with the EMC Directive 2004/108/EC and is CE marked

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2 Ensuring we provide and maintain optimal environmental conditions for our patients embryos whilst ex-vivo is one of the most fundamentally essential tasks of a successful lab. REGULATORY COMPLIANCE Each device complies with the EMC Directive 2004/108/EC and is CE marked 1 Ronny Janssens, Centre for Reproductive Medicine, UZB, Brussels, Belgium

3 ENVIRONMENTAL MONITORS Optimising the Quality of your Laboratory Working Environment PORTABLE Every monitor from RI can be operated on battery power for convenience SAFE By monitoring important parameters independently, the best safety standards can be maintained ACCURATE Our monitors offer exacting measurements with streamlined maintenance and calibration processes 2

4 PH METER 3 PH LEVEL MONITOR Building on the success and popularity of our ph Meter, RI now offers a new compact version. Smaller, lighter and with an improved probe, it allows you to measure media in real time from inside any popular incubator, including benchtop models. The redesigned user interface guides you quickly through the calibration process. With the ph Meter 3 you can see the ph of a media sample during culture to better inform lab protocols and optimise conditions. The ph Meter 3 is suitable for various laboratory surveys and is compatible with standard media equilibration practices. The amount of data storage has been increased to 2GB in anticipation of transfer to your PC for analysis by our dedicated software using adaptable graphs to display the ph and the temperature over time. Details can also be archived, reported to other software programs and printed for lab records. ph Accuracy ph Calibration Calibration Temperature Accuracy Protection Rating ±0.02pH 2-point at room temperature, followed by 1-point at 37 C RI supplied buffers with ph 7 and 10 ±0.5 C / 0.9 F IP65 (dustproof, water resistant) Operation Time on Battery Data-logging Data Export Dimensions 8 hours typical with display on and 26 hours with display off 2GB internal memory Data export to PC with dedicated software provided 8cm x 16cm x 3.6cm ACCURATE UNIQUE COMPATIBLE 3 New digital ph Meter readings with excellent calibration response and repeatability IVF culture dish design and improved robust probe Suitable for use with all popular incubators including benchtop versions

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6 IVF THERMOMETER I consider this an essential piece of kit for the correct function of our lab and quality system. Sue Pickering, NHS Lothian, Edinburgh, Scotland 5

7 ACCURATE TEMPERATURE MEASUREMENT Consistently good temperature control is one of the best ways to optimise results in the ART laboratory. Labs use the IVF Thermometer to verify that any heated equipment which comes into contact with live samples is performing as required. The specifically designed microprobe allows the user to accurately measure the temperature of heated stages and inside media droplets, incubators and refrigerators. The probe can be held in place or fitted to a holder for hands-free measurement. The probe is also insulated against heat from the user for truly accurate measurements. The optional cryo-probe has been tested extensively in liquid nitrogen and functions down to -200 C. Accuracy Certification Points Operation Time on Battery Dimensions Weight (including batteries) UKAS-certified offset. Measurement at calibration temperatures repeatable to ±0.2 C 5 C (41 F) 37 C (98.6 F) 45 C (113 F) 500 hours typical 15.5cm x 6.7cm x 4.0cm 250g VERSATILE SIMPLE PRACTICAL Cryo and extra robust probe options available Ergonomic design with large backlit digital display Unique microprobe for microdrop measurement 6

8 VOC METER VOC LEVEL MONITOR The RI VOC Meter is capable of detecting contamination at 0.1 parts per million (ppm) level. 0.1ppm is below an established threshold of embryo toxicity 1. It is the most advanced, sensitive and reliable handheld VOC detector on the market. The VOC Meter is available with or without datalogging. Designed as a safeguard, the unit can be wall-mounted and VOC levels logged at desired intervals. The concentration of VOCs present is displayed on the screen. If a higher than recommended concentration of VOCs is detected, an audible alarm will sound. Test results stored in the RI VOC Meter may be easily downloaded to a personal computer for analysis and printing. With the software provided users can sort and view results with ease. Parts per billion model also available. 1 Hall J. et al, The origin, effects and control of air pollution in laboratories used for human embryo culture, Human Reproduction, Vol. 13 Suppl. 4, pages Sensor Response Time Calibration Data-logging (yellow) Non data-logging (green) Photo-ionisation detector (PID) Photo-ionisation detector (PID) 0 to 15,000 ppm 0 to 10,000 ppm < 3 sec Isobutylene gas Flow Rate 500 cc/min 400cc/min 0% to 95% relative humidity Operating Humidity (non-condensing) Operating Temperature Range Operation Time on Battery Data-logging (optional) Data Export (optional) Dimensions Weight (including batteries) -20 C to 50 C (-4 to 122 F) 16 hours typical (12 hours with alkaline battery) 6 month capacity at 1 minute intervals. Intervals user configurable N/A from 1 to 3600 seconds PC compatible through USB port in charging cradle. Optional Bluetooth N/A or wireless data transmission through built-in RF modem 25.5cm x 7.6cm x 6.4cm 738g SENSITIVE DATA LOGGING PROVEN 7 Up to 200 times more sensitive to VOCs than conventional Heated Metal Oxide Sensors (HMOS) 6 month capacity of data at one minute intervals can be downloaded to a PC Proven Photo Ionisation Detection (PID) technology. The patented 3D sensor provides three second response from 0.1 ppm to 15,000 ppm

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10 PARTICLE COUNTER AIR QUALITY MONITOR The HandiLaz Mini can be used to measure the particle concentration of air in safety cabinets, cleanrooms, and HEPA filtered incubators. It provides an on-the-spot check that your air quality is as it should be, and that your air filtration system is producing Grade A air to ISO or EU GMP standards. The particle counter is calibrated by NIST traceable particles and adheres to the same standards that an independent inspector does. The HandiLaz Mini interfaces directly by cable to an optional printer or PC. Sensor Channel Thresholds Calibration Max Concentration (@5% coincidence error) Flow Rate Laser 3 channels: 0.3, 0.5 and 5µm NIST- traceable particles 70 x 10 6 counts/m l/min. (0.1 ft 3 /min) Units Operation Time on Battery Data-logging Data Export Dimensions Weight (excluding batteries) Counts, Counts/m 3, Counts/ft 3 3 hours typical Stores up to 10,000 readings Report and data export to CSV file 11cm x 20cm x 7cm 680g QUICK PRACTICAL EXTREMELY ACCURATE 9 A basic scan will take <1 minute Up to 10,000 readings can be stored Counts particles as small as 0.3 microns

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12 Research Instruments Ltd, Bickland Industrial Park, Falmouth, Cornwall, TR11 4TA, UK tel: +44 (0) fax: +44 (0) visit: MKTG-BR /05/2015. All information correct at the time of print. Specifications are subject to change without notice or obligation on the part of the manufacturer.