Mya 4 Reaction Station

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Mya 4 Reaction Station One reaction station with limitless possibilities 4 independent zones Magnetic and overhead stirring -30 C to +180 C 2 ml to 400 ml Software control Process Package Let Daisy introduce our Mya 4 Video /mya4

Mya 4 - Key Features A 4-zone reaction station offering safe and precise heating, active cooling, software control and data-logging for 24/7 unattended chemistry -30 C 180 C Wide range of vessels from 2 ml to 400 ml Vials, tubes, round bottom flasks and process vessels Temperature -30 C to +180 C Independent control of each zone Block or solution control Pt100 temperature probes Mya Compact Stirrer Stirs from 100 to 1000 rpm Control each position independently Powerful, high torque motor Tool-free attachment Up to 200 C difference in adjacent zones High performance insulation minimises zone cross-talk Manifold Head Distributes water for condensers Distributes gas for inerting Excellent visibility Easily view your vessel contents Cool to -25 C with tap water No need for a separate chiller Powerful Peltier technology provides rapid cooling Magnetic stirring from 100 to 1000 rpm Control each position independently Space saving Compact benchtop footprint Less space than 4 separate reaction set-ups Touch-screen Control Pad Supplied as standard Intuitive and easy to use Set automated profiles or use manual control Single or multi-user operation Control heating/cooling and stirring of each zone independently Optional PC Control Software Integrate and control 3rd party devices such as pumps, balances and ph sensors 2 Radleys Shire Hill, Saffron Walden, Essex, CB11 3AZ. United Kingdom

Mya 4 - Overview A flexible process development tool for design of experiment, scale up, reaction optimisation, and crystallisation studies Flexible and versatile 4 different temperature zones, each with heating and active cooling Use one compact system for a range of experiments Accepts a wide range of vessel sizes and styles Control your experiments and log results automatically Applications Single or parallel synthesis Design of Experiment (DoE) Process development Scale up Route scouting Crystallisation studies Polymorph screening Lead optimisation Reaction optimisation Reagent, catalyst and solvent screening Safer, cleaner, greener and more productive Replace inefficient, messy and unsafe oil and ice baths Save space compared with separate reaction set-ups Software control improves safety, reduces manual errors, and allows 24/7 unattended chemistry, for improved productivity Create, repeat and share experiments and results with ease and accuracy Easily manage complex multi-step and multi-device experiments Integrate 3rd party devices such as pumps, balances and ph sensors etc. Touch-screen Control Pad Optional PC Control Software t: +44 1799 513320 f: +44 1799 513283 e: sales@radleys.co.uk 3

Mya 4 - Details One flexible reaction station to meet all of your needs. Choose from a wide selection of vials, tubes, round bottom flasks and process vessels, from 2 ml to 400 ml 4 reaction zones -30 C Use 1, 2, 3 or 4 zones Operate zones in parallel or individually by multiple users Removable anodised aluminium inserts for different size vessels 180 C Wide selection of vessel styles and volumes Vials and tubes from 2 ml to 50 ml: --12 mm, 16 mm, 17 mm, 17 mm tapered, 24 mm, 1 inch and 28 mm diameters --Radleys Carousel 12 Plus reaction tubes Round bottom flasks from the Carousel 6 Plus range: --25 ml, 50 ml, 100 ml and 250 ml --One or two side arm options --Standard and wide neck options --Baffled vessel options Process reaction vessels: --With straight sides and dished base to mimic jacketed reactors --50 ml, 100 ml, 150 ml, 250 ml and 400 ml --Side arm option --Baffled vessel options Multi-neck glass lids - 3 or 5-neck --For wide neck round bottom flasks and process vessels Accessory glassware --Condensers, dropping funnels, solid addition funnels, stoppers etc. Precise temperature control Temperature range from -30 C to +180 C Up to 200 C difference between adjacent positions Control the temperature of each zone independently Choose to control by block or solution temperature Pt100 temperature probes available in stainless steel or PTFE coated Use Mya 4 with or without a chiller Mya 4 uses powerful Peltier technology to provide rapid cooling to -30 C Peltier cells require tap or chilled water to dissipate heat Peltier cooling source Tap water at 15 C Chilled water at 5 C Minimum block temperature -25 C -30 C Minimum solution temperature -20 C -25 C Magnetic or optional overhead stirring Integrated magnetic stirring - from 100 to 1000 rpm Optional overhead stirring - from 100 to 1000 rpm Control the stirring speed of each position independently Use magnetic or overhead stirring in adjacent zones Mya Compact Stirrer 4 Radleys Shire Hill, Saffron Walden, Essex, CB11 3AZ. United Kingdom

Mya 4 - Control Options Take control of your chemistry with 24/7 unattended software control for improved productivity, safety and reduced manual errors Touch-screen Control Pad Supplied as standard with Mya 4 Intuitive and easy to use Compact footprint Set automated profiles or use manual control PC Control Software - optional Integrate and control 3rd party devices Create complex experiments with any number of steps Report Wizard creates reports in rich text format or export results in CSV Control Options Features Touch-screen Control Pad PC Control Software Touch-screen Control Pad is supplied as standard with Mya 4 Included Optional Intuitive and easy to use touch-screen control Compact footprint - fumehood compatible Maximum 10 steps of 16 hours each Multi-user - independently run experiment in 4 zones Control and log the temperature and stirring of each zone independently Set safety limits Export experimental profiles and results in CSV via USB memory stick Adjust parameters manually - using manual/direct mode Create multi-step recipes - using profile/schedule mode Flexibility to make and track on-the-fly adjustments to your experiment Automatically log all data Share experimental results and recipes with other users View real-time graphs Control and log up to 16 x 3rd party devices on one screen Create complex experiments with any number of steps Interlink devices and set feedback/control loops and end point conditions Report Wizard creates detailed reports in RTF or export results in CSV Log comments Runs on a Windows laptop Control 3rd party devices PC Control Software will control and log the following 3rd party devices: Syringe Pumps ph Sensors Peristaltic Pumps Balances Vacuum Pumps Gas Flow Controllers Pressure Sensors Conductivity Sensors Let Daisy introduce our Mya 4 Video /mya4 t: +44 1799 513320 f: +44 1799 513283 e: sales@radleys.co.uk 5

How to order a Mya 4 Process Package 1. Select manifold head Mya 4 - Process Package Choose the manifold head for use with glass condensers, overhead stirrers and process vessels; ideal for mimicking jacketed reactors 2. Select vessel style Process Package for: Process development Design of Experiment (DoE) Polymorph screening Crystallisation studies Route scouting 3. Select a multi-neck lid & condenser 4. Select inserts 5. Select accessories 6. Select overhead stirrer and paddle 7. Optional - Select PC control software 6 Radleys Shire Hill, Saffron Walden, Essex, CB11 3AZ. United Kingdom

Mya 4 - Discovery Package Choose the reflux head for integrated reflux cooling; combines well with magnetic stirring; ideal for use with round bottom flasks How to order a Mya 4 Discovery Package 1. Select reflux head Discovery Package for: Lead optimisation Single or parallel synthesis Reaction optimisation Reagent, catalyst & solvent screening Crystallisation studies 2. Select vessel style 3. Select standard or wide neck reflux tubes and Easy-On caps 4. Select inserts Alternative DISCOVERY Set-up 5. Select accessories 6. Select magnetic stirring bars 7. Optional - Select PC control software t: +44 1799 513320 f: +44 1799 513283 e: sales@radleys.co.uk 7

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