Boxed messages as shown below need your special attention. Read them carefully.

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Introduction Thank you for choosing MEQNET WINDRIVER for Lactate Pro TM 2. This Operating Manual explains how to use this software in order to obtain blood lactate data stored in lactate analyzers manufactured by ARKRAY and to save CSV files. Please read this manual carefully before use. Definitions Terms used in this Operating Manual Select Select items or icons on the screen by using a mouse or keyboard. Start up Start up applications such as this software. You can freely customize how to start up applications on Windows. Operate in a way suitable for the environment. Click Press the left button of the mouse once. Terms frequently used in this Operating Manual This software MEQNET WINDRIVER for Lactate Pro TM 2 is referred to as this software in this manual. Meter Lactate Pro TM 2 LT-1730, a lactate analyzer manufactured by ARKRAY Special cable USB communication cable for this software only. This cable is sold separately. Contact our authorized distributor for further information. CSV file Text file separated with comma (Comma-Separated Values) <Screen name> Name of screens indicated in parentheses < > <Main Menu> The screen that appears when you start this software. Desktop The screen that appears when you start up Windows. Boxed messages as shown below need your special attention. Read them carefully. Example: *Data on [CSV file] are the original information of data analysis. Use great care when entering / changing data. Note Contents of this software may be changed without notice. Figures in this manual may differ from actual screens. Download the latest version of this software from the following website: http://www.arkray.co.jp/english/index.html (member registration necessary) MEQNET WINDRIVER 1

CONTENTS Introduction... 1 Definitions... 1 Note... 1 1. Overview of this software... 3 1.1 Features... 3 1.2 Hardware Environment... 3 2. Software Installation... 4 2.1 Installation... 4 3. Start-up and exit out of software... 9 3.1 How to start up the program... 9 3.2 How to exit the program... 10 4. Screen Layout... 11 4.1 Main Menu... 11 4.2 Setup of communication conditions... 12 5. Operation Flow... 13 5.1 Basic operation flow... 13 5.2 How to receive data... 14 6. CSV File... 16 6.1 What is CSV file?... 16 6.2 CSV Data Format... 16 7. Uninstallation... 17 7.1 How to uninstall... 17 8. Troubleshooting... 18 8.1 If an error message appears... 18 9. Symbol... 18 2 MEQNET WINDRIVER

1. Overview of this software 1.1 Features This software makes it possible to receive blood lactate data stored inside meters manufactured by ARKRAY and save them in CSV file format. *CSV file is one of file formats, which can be consulted / edited using Microsoft Excel or Notepad. *Data on [CSV file] are the original information for data analysis. Use great care when entering / changing data. 1.2 Hardware Environment This software complies with the hardware environment below: CPU Applicable OS operation environment (Windows 7 environment recommended) Memory Applicable OS operation environment (Windows 7 environment recommended) OS Windows XP (SP3 or later) / Windows Vista / Windows 7 *Microsoft, Windows logo, and the Windows Start logo are either registered trademarks or trademarks of Microsoft Corporation in the United States and/or other countries. Library Microsoft.NET Framework 2.0 SP2 or later Hard Disc 50 MB disc space or more (recommended 100 MB disc space or more) Display 800 600 dots or higher Resolution Font Size Only small font is acceptable Others Necessary environment: USB Port, Mouse *Service pack application is necessary. MEQNET WINDRIVER 3

2. Software Installation 2.1 Installation Follow the steps below before installing this software: 1. Download MEQNET WINDRIVER from ARKRAY s website. 2. When you download installation program from the website, select a folder (ex. My Documents) for downloading the program. Installation procedure 1. Before installation, log on to Windows as an administrator or user with administrative authority and turn off all active software and virus checkers. * If you are not sure about the installation of this software, contact your system administrator or IT support. 2. Install this software without connecting the special cable in the computer. Insert the special cable after the following steps. 3. Use Explorer or My Computer to open the folder where the installation program is saved, and double click meqwdxxx_en.exe (XXX:Version No.). 4. The following warning may appear depending on your security settings. When this appears, click [Yes]. 4 MEQNET WINDRIVER

5. A message appears indicating the installation is underway. * Ver3.00 on the title bar may change without notice. * If the same version of MEQNET WINDRIVER is already installed, the following message appears. In such case, uninstall the program once and reinstall. For details, see chapter 7 Uninstallation. (Even if you uninstall this software, CSV files will not be deleted.) When the installation wizard appears, click [Next>]. MEQNET WINDRIVER 5

6. License Agreement appears. Read carefully. If you agree to the content, select I accept the terms in the license agreement. and click [Next>]. 7. Enter customer information and click [Next>]. 6 MEQNET WINDRIVER

8. If you need to change the destination folder, click [Change]. If not, click [Next>]. *Do NOT select a root folder as a destination folder. 9. The following message appears. Click [Install] to start installation. *When user account control screen appears for Windows 7 click [Yes] or [Allow]. (User account control is a function to notify the user before any changes to the used computer take place that require access permit at administrator level.) MEQNET WINDRIVER 7

10. When completion screen appears, click [Finish]. 11. This is the end of installation procedure. 8 MEQNET WINDRIVER

3. Start-up and exit out of software 3.1 How to start up the program Before starting up this software, special cable needs to be connected to the USB port of the computer. Special cable PC 1. Click MEQNET WINDRIVER icon on the desktop or click [Start] -> [Program] -> [ARKRAY] -> [MEQNET WINDRIVER] -> [MEQNET WINDRIVER for Lactate Pro2]. Start up from the shortcut icon on the desktop Start up from start button MEQNET WINDRIVER 9

2. <Main Menu> appears. If the following error appears before <Main menu>, the special cable has not been set up. Set up the port No. in chapter 4.2 Setup of communication conditions. 3.2 How to exit the program 1. Click [Exit] in <Main Menu>. 10 MEQNET WINDRIVER

4. Screen Layout 4.1 Main Menu <Main Menu> appears when starting up this software. * You will start from this screen when receiving data from the meter. For details, see chapter 5.2 How to receive data. When using other functions, select an icon in the <Main Menu>. Communication setting Exit Setup screen for communication conditions appears. Exit this software. MEQNET WINDRIVER 11

4.2 Setup of communication conditions <Communication condition setup> screen appears when you click [communication setting]. Display setting of device manager and port No. can be changed. Port No. Port No. can be set as 1 ~ 255. Bits per second Communication speed cannot be changed from 19200 bits. Data length Data length cannot be changed from 8. Parity Parity cannot be changed from NON. Stop bit Stop bit cannot be changed from 2. Device manager Device manager is displayed. OK Save changes. Cancel Close <Communication condition setup> screen and return to the <Main Menu>. 12 MEQNET WINDRIVER

5. Operation Flow 5.1 Basic operation flow The following flowchart describes the basic operations after installing this software. 1. When you use this software for the first time, register basic information and setup communication port as necessary. 2. Receive blood lactate data from the meter. 3. Save received data in CSV file format on your computer. 4. Use the saved CSV file for analysis, etc. based on your own decision. MEQNET WINDRIVER 13

5.2 How to receive data *Follow the instructions on the screen when you receive data from a meter. Do NOT remove the connected cable or turn off the meter during data transfer. This may result in a failure. * The measurement unit indicated in the instruction below is mg/dl. 1. Connect the special cable to the computer and start up the software. Connect the cable as shown below while <Main Menu> is on. 2. A message for processing appears on <Main Menu>. * Do NOT remove the cable during data transfer. If the cable is removed, communication is interrupted and cannot continue. Close and restart this software, and reinsert the cable into the meter. 14 MEQNET WINDRIVER

3. Save File (Windows 7, Vista) or Save As (Windows2000, XP) appears. Click [Save]. File name can be changed. Default file name: 1730-[meter serial No.]-yyyyMMddHHmmss.csv Example) When meter serial No. is:1730-1234567 1730-1234567-20101020161029.csv * yyyymmddhhmmss stands for year, month, date, hour, minute and second. Default file location: My Document (when OS is Windows XP) 4. When the following message appears, click [OK]. 5. Remove the cable from the meter. 6. Confirm that file is exported properly. * CSV file to be output is stored in a format described in chapter 5.4 CSV Data Format. MEQNET WINDRIVER 15

6. CSV File 6.1 What is CSV file? CSV file is one of file formats, which can be consulted / edited using Microsoft Excel or Notepad. You can save/import received data, manually input data or patient information in CSV file using this software. *Data on [CSV file] are the original information of data analysis. Use great care when entering / changing data. *Please set the delimiter for CSV file depending on your Windows decimal symbol setting as follows: a) If the Windows decimal symbol setting is comma (,), please use semicolon (;) as the CSV delimiter. b) If the Windows decimal symbol setting is period (.), please use comma (,) as the CSV delimiter. 6.2 CSV Data Format Explanations of each item Items Tested date Tested time Test result (measurement unit) Hi/Lo Delete Temperature warning Measurer code Description Date when blood lactate level was tested. Time when blood lactate level was tested. Blood lactate level received from the meter. Measurement unit is changed according to the unit of the meter. Hi indicates a result higher than 25.0 mmol/l (225 mg/dl), and Lo indicates a result lower than 0.5 mmol/l (5 mg/dl). Delete is indicated if delete symbol was saved by button operation of the meter. Temperature warning is indicated when tested outside environment temperature range and thermometer symbol appeared on the meter screen. Measurer code (M01, M02, M03) is indicated if it was selected on the meter for the test. Example of CSV: in mg/dl unit Test date,time,test results,hi/lo,delete,temperature warning,group No. 2012/02/13,13:13,95,,,,0 2012/02/14,14:14,93,,,,0 2012/02/15,15:15,91,,,,0 2012/02/16,16:16,89,,,,0 16 MEQNET WINDRIVER

7. Uninstallation 7.1 How to uninstall This chapter explains how to uninstall this software. CSV files will not be deleted even if this software is uninstalled. Procedure 1. Click [Start] button and select [Setting] -> [Control Panel] to display control panel window 2. Double-click the following icon in [Control Panel] window. Windows 7, Vista: Windows XP: Others: Uninstall Program Add or Remove Programs Add/Remove Programs 3. Select [MEQNET WINDRIVER for Lactate Pro2 Ver3.00], then click [uninstall]. 4. The following message appears. Click [Yes] to uninstall this software. * For Windows 7 and Vista, user account control screen appears. Click [Yes] or [Allow]. MEQNET WINDRIVER 17

8. Troubleshooting 8.1 If an error message appears This chapter describes what the errors are and actions that should be taken. Error message MEQNET WINDRIVER is already running. The port COM? does not exist. E417-A03 Communication between instruments failed. What to do 1. Check if this software is already running. 1. Check if the special USB cable is connected to the USB port. -> If not, connect the cable and start this software. 2. Check if the cable driver software (packed with the special USB cable) is installed. 3. Check if the OS recognizes the target port. -> From Communication condition setup, click Device manager button and check that Port (COM and LPT) is added in the device manager. For more details, refer to the setup guide that comes with the USB cable. If communication does not start, check the display from Device manager. 1. Cable was removed during data transfer. Connect the cable again and import data. 9. Symbol Symbol Description Lactate Pro TM 2 conforms to the Directive 98/79/EC In Vitro Diagnostic Medical Suitable for self testing 18 MEQNET WINDRIVER