Medical Information Literature Search : PubMed Bordin Sapsomboon 9 Mar 2016 http://www.si.mahidol.ac.th/simi bordin.sap@mahidol.ac.th Objectives Know Medical informatics Literature search : PubMed PICO Approach Do Searching : PubMed Keywords formation Advanced level : MeSH, PICO Evaluation 2 3 1
Why Search for Medical Information? 5 Roles (Medical Informatics) Life-long learner Clinician Researcher Teacher/Communicator Manager 4 Skeptic ช างตกม น http://bit.ly/ewuepy นาฬาค ร http://bit.ly/y2htvj 5 Human and Information 6 2
Skeptic 7 Searching : Detective 8 9 3
Speak Google s Language Latest mobile phones Models of 2015 Not Samsung gphones Brain cancer Brain cancer Cancer treatment site:harvard.edu Photo search 10 Advanced Search 11 12 4
13 Google: Doctor s Handbook! 14 Information : Certainty Belief Opinion Fact & Knowledge Truth 15 5
What is Information? Information vs Medical Information 16 Information Source Document Journal article Research paper Newspaper Magazine E-document Web : Google E-Journal : Publisher 17 18 6
Databases Internet Database Newspaper Public database Literature Database PubMed Ovid OCLC Science Direct 19 Siriraj Medical Library Databases 20 21 7
Literature Search Text matching Word or Words All documents contains the word SARS any where Keywords Synonyms All documents about SARS 22 Strategies for Literature Search Number of Items Found Too many v.s. Too few Relevancy Broad v.s. Specific Relevant v.s. Irrelevant 23 Search Tools Boolean operators AND, OR, NOT, ( ) Fields in article / database Title, Abstract, Author, UI number MEDLINE database Filter - Limit Medical Subject Headings (MeSH) 24 8
Strategies : Broaden Synonym AIDS, HIV Thesaurus Infant, Toddler Boolean operator Pepsi OR Coke Heading automobile 25 Strategies : Narrow More keywords Red blood cell diseases Boolean operator AIDS AND Thailand Thalassemia NOT THAILAND Heading radiotherapy (only) 26 Relevancy Find SARS and Cause AIDS in Children Lung cancer and radiotherapy Mobile phone in 2007 All articles about lung cancer All articles by Dr. Robinson 27 9
Strategies : Relevancy Broaden and Narrow-down Database tools Limits : AIDS in English language g Query language MeSH 28 Database Query Find lung cancer "lung neoplasms"[mesh Terms] OR lung cancer[text Word] 29 MeSH Medical Subject Headings Heading Diseases Subheading Virus Diseases 30 10
MeSH : Example Virus Diseases RNA Virus Infections Nidovirales Infections Coronaviridae Infections Coronavirus Infections [C02.782.600.550.200] 31 Clinical Questions Background question General question Ans: Overview, Review, EMB, standards, therapy Foreground question Complex / patient-centered question Approach: PICO (formulating clinical queries) PICO Patient / Problem Diagnosis Intervention Diagnostic i test Comparison / Control Outcomes / Effects Prognosis Methodology Prevention / therapy 11
PICO : Example (1) There is a section of town which has a high prevalence rate of obesity and diabetes. There are many churches in that area so you decide to work with the churches to develop a series of interventions to reduce both obesity and diabetes. One of the programs will target foods served at church-sponsored events which are mostly pot-luck. https://sph.uth.edu/charting/handouts/ebph_handouts/pico.pdf PICO : Example (2) Population: members of a group of churches in an area of town Intervention: program designed to improve types of foods served at churchsponsored events Comparison: foods served before the intervention Outcome: Are more nutritious foods served at church-sponsored events after the intervention? Relevant Found Existing Documents Search Strategy Word Keywords Operator MeSH Multiple resources Document Space Relevant Documents Found Documents 36 12
Relevant Documents Matching Perfect Partial Scoring / Ranking 100% = Perfect matching Calculation Frequency of the search word appeared in the document 37 SARS Bird Flu SARS Document Space Relevant Documents 38 Relevant Information Source Use relevant information source! Medical information MEDLINE database www.pubmed.org General information Start with good search engines? 39 13
Relevant Documents Perfect matching Matching to your NEEDS Not perfect TEXT matching 40 Find Sars Coronavirus Etiology / Cause Mobile phone Brain tumor Risk Shoulder dislocation Joint instability 41 14