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\\USER\INVESTIGATORS\Ravi\ADNI-Subject\Localizer TA: 0:10 PAT: Voxel size: 1.9 1.5 8.0 mm Rel. SNR: 1.00 SIEMENS: gre Properties Prio Recon Before measurement After measurement Load to viewer Inline movie Auto store images Load to stamp segments Load images to graphic segments Auto open inline display AutoAlign Spine Start measurement without further preparation Wait for user to start Start measurements single Routine Slice group 1 Slices 1 Dist. factor 20 % Position Isocenter Slice group 2 Slices 1 Dist. factor 20 % Position Isocenter Slice group 3 Slices 1 Dist. factor 20 % Position Isocenter 9 Phase oversampling 0 % FoV read 280 mm FoV phase 100.0 % Slice thickness 8.0 mm TR 20.0 ms TE 5.00 ms Averages 1 Concatenations 3 Filter Raw filter, Distortion Corr.(2D), Normalize Coil elements HE1-4 Contrast TD MTC Magn. preparation Flip angle Fat suppr. Water suppr. SWI 0 ms 40 deg Averaging mode Short term Reconstruction Magnitude Measurements 1 Multiple series Each measurement Resolution Base resolution 192 Phase resolution 75 % Phase partial Fourier Interpolation PAT mode Matrix Coil Mode Auto (CP) Distortion Corr. Mode 2D Unfiltered images Prescan Normalize Normalize Raw filter Intensity Weak Slope 25 Elliptical filter Geometry Multi-slice mode Series Sequential Ascending Saturation mode Special sat. Set-n-Go Protocol Inline Composing System Body HE1 HE3 HE2 HE4 H 0 mm Positioning mode MSMA Save uncombined Coil Combine Mode Auto Coil Select REF S - C - T Adaptive Combine Default Shim mode Adjust with body coil Confirm freq. adjustment Assume Silicone Ref. amplitude 1H Adjustment Tolerance Adjust volume Position Tune up 205.057 V Auto Isocenter 350 mm 263 mm 350 mm Physio 1st Signal/Mode Segments 1 Tagging Dark blood 1/+

Resp. control Inline Subtract Liver registration Std-Dev-Sag Std-Dev-Cor Std-Dev-Tra Std-Dev-Time MIP-Sag MIP-Cor MIP-Tra MIP-Time Save original images Wash - In Wash - Out TTP PEI MIP - time Sequence Introduction Dimension 2D Phase stabilisation Asymmetric echo Contrasts 1 Bandwidth 180 Hz/Px Flow comp. No RF pulse type Gradient mode Excitation RF spoiling Normal Slice-sel. 2/+

\\USER\INVESTIGATORS\Ravi\ADNI-Subject\MPRAGE TA: 7:42 PAT: Voxel size: 1.3 1.3 1.2 mm Rel. SNR: 1.00 SIEMENS: tfl Properties Prio Recon Before measurement After measurement Load to viewer Inline movie Auto store images Load to stamp segments Load images to graphic segments Auto open inline display AutoAlign Spine Start measurement without further preparation Wait for user to start Start measurements single Routine Slab group 1 Slabs 1 Dist. factor 50 % Phase oversampling 0 % Slice oversampling 20.0 % Slices per slab 160 FoV read FoV phase 100.0 % Slice thickness 1.20 mm TR 2400 ms TE 3.5 ms Averages 1 Concatenations 1 Filter Coil elements HE1-4 Contrast Magn. preparation TI Flip angle Fat suppr. Water suppr. Non-sel. IR 1000 ms 8 deg Averaging mode Long term Reconstruction Magnitude Measurements 1 Multiple series Resolution Base resolution 192 Phase resolution 100 % Slice resolution 100 % Phase partial Fourier Slice partial Fourier Interpolation PAT mode Matrix Coil Mode Auto (CP) Distortion Corr. Prescan Normalize Normalize Raw filter Elliptical filter Geometry Multi-slice mode Series Single shot Set-n-Go Protocol Inline Composing System Body HE2 HE4 HE1 HE3 SP4 SP2 SP8 SP6 SP3 SP1 SP7 SP5 H 0 mm Positioning mode MSMA Save uncombined Coil Combine Mode Auto Coil Select REF S - C - T Sum of Squares Default Shim mode Adjust with body coil Confirm freq. adjustment Assume Silicone Ref. amplitude 1H 205.057 V Adjustment Tolerance Auto Adjust volume 192 mm Physio 1st Signal/Mode Dark blood Resp. control Inline Subtract Std-Dev-Sag Std-Dev-Cor Std-Dev-Tra Std-Dev-Time MIP-Sag MIP-Cor MIP-Tra MIP-Time Save original images 3/+

Sequence Introduction Dimension 3D Elliptical scanning Asymmetric echo Bandwidth 180 Hz/Px Flow comp. No Echo spacing 7.9 ms RF pulse type Gradient mode Excitation RF spoiling * Non-sel. 4/+

\\USER\INVESTIGATORS\Ravi\ADNI-Subject\MPRAGE Repeat TA: 7:42 PAT: Voxel size: 1.3 1.3 1.2 mm Rel. SNR: 1.00 SIEMENS: tfl Properties Prio Recon Before measurement After measurement Load to viewer Inline movie Auto store images Load to stamp segments Load images to graphic segments Auto open inline display AutoAlign Spine Start measurement without further preparation Wait for user to start Start measurements single Routine Slab group 1 Slabs 1 Dist. factor 50 % Phase oversampling 0 % Slice oversampling 20.0 % Slices per slab 160 FoV read FoV phase 100.0 % Slice thickness 1.20 mm TR 2400 ms TE 3.5 ms Averages 1 Concatenations 1 Filter Coil elements HE1-4 Contrast Magn. preparation TI Flip angle Fat suppr. Water suppr. Non-sel. IR 1000 ms 8 deg Averaging mode Long term Reconstruction Magnitude Measurements 1 Multiple series Resolution Base resolution 192 Phase resolution 100 % Slice resolution 100 % Phase partial Fourier Slice partial Fourier Interpolation PAT mode Matrix Coil Mode Auto (CP) Distortion Corr. Prescan Normalize Normalize Raw filter Elliptical filter Geometry Multi-slice mode Series Single shot Set-n-Go Protocol Inline Composing System Body HE2 HE4 HE1 HE3 SP4 SP2 SP8 SP6 SP3 SP1 SP7 SP5 H 0 mm Positioning mode MSMA Save uncombined Coil Combine Mode Auto Coil Select REF S - C - T Sum of Squares Default Shim mode Adjust with body coil Confirm freq. adjustment Assume Silicone Ref. amplitude 1H 205.057 V Adjustment Tolerance Auto Adjust volume 192 mm Physio 1st Signal/Mode Dark blood Resp. control Inline Subtract Std-Dev-Sag Std-Dev-Cor Std-Dev-Tra Std-Dev-Time MIP-Sag MIP-Cor MIP-Tra MIP-Time Save original images 5/+

Sequence Introduction Dimension 3D Elliptical scanning Asymmetric echo Bandwidth 180 Hz/Px Flow comp. No Echo spacing 7.9 ms RF pulse type Gradient mode Excitation RF spoiling * Non-sel. 6/+

\\USER\INVESTIGATORS\Ravi\ADNI-Subject\B1-calibration Head TA: 0:42 PAT: Voxel size: 2.3 2.3 2.5 mm Rel. SNR: 1.00 SIEMENS: gre Properties Prio Recon Before measurement After measurement Load to viewer Inline movie Auto store images Load to stamp segments Load images to graphic segments Auto open inline display AutoAlign Spine Start measurement without further preparation Wait for user to start Start measurements single Routine Slab group 1 Slabs 1 Dist. factor 20 % Phase oversampling 0 % Slice oversampling 0.0 % Slices per slab 96 FoV read 300 mm FoV phase 100.0 % Slice thickness 2.50 mm TR 3.3 ms TE 1.08 ms Averages 1 Concatenations 1 Filter Coil elements HE1-4 Contrast MTC Magn. preparation Flip angle Fat suppr. Water suppr. SWI 2 deg Averaging mode Long term Reconstruction Magnitude Measurements 1 Multiple series Each measurement Resolution Base resolution 128 Phase resolution 100 % Slice resolution 100 % Phase partial Fourier Slice partial Fourier Interpolation PAT mode Matrix Coil Mode Auto (CP) Distortion Corr. Prescan Normalize Normalize Raw filter Elliptical filter Geometry Multi-slice mode Series Saturation mode Special sat. Set-n-Go Protocol Inline Composing System Body HE2 HE4 HE1 HE3 SP4 SP2 SP8 SP6 SP3 SP1 SP7 SP5 H 0 mm Positioning mode MSMA Save uncombined Coil Combine Mode Auto Coil Select REF S - C - T Sum of Squares Default Shim mode Adjust with body coil Confirm freq. adjustment Assume Silicone Ref. amplitude 1H 205.057 V Adjustment Tolerance Auto Adjust volume 300 mm 300 mm Physio 1st Signal/Mode Segments 1 Tagging Dark blood Resp. control Inline Subtract Liver registration Std-Dev-Sag Std-Dev-Cor Std-Dev-Tra Std-Dev-Time 7/+

MIP-Sag MIP-Cor MIP-Tra MIP-Time Save original images Wash - In Wash - Out TTP PEI MIP - time Sequence Introduction Dimension 3D Elliptical scanning Phase stabilisation Asymmetric echo Contrasts 1 Bandwidth 980 Hz/Px Flow comp. No RF pulse type Gradient mode Excitation RF spoiling Non-sel. 8/+

\\USER\INVESTIGATORS\Ravi\ADNI-Subject\B1-calibration Body TA: 0:42 PAT: Voxel size: 2.3 2.3 2.5 mm Rel. SNR: 1.00 SIEMENS: gre Properties Prio Recon Before measurement After measurement Load to viewer Inline movie Auto store images Load to stamp segments Load images to graphic segments Auto open inline display AutoAlign Spine Start measurement without further preparation Wait for user to start Start measurements single Routine Slab group 1 Slabs 1 Dist. factor 20 % Phase oversampling 0 % Slice oversampling 0.0 % Slices per slab 96 FoV read 300 mm FoV phase 100.0 % Slice thickness 2.50 mm TR 3.3 ms TE 1.08 ms Averages 1 Concatenations 1 Filter Coil elements BC Contrast MTC Magn. preparation Flip angle Fat suppr. Water suppr. SWI 2 deg Averaging mode Long term Reconstruction Magnitude Measurements 1 Multiple series Each measurement Resolution Base resolution 128 Phase resolution 100 % Slice resolution 100 % Phase partial Fourier Slice partial Fourier Interpolation PAT mode Matrix Coil Mode Auto (CP) Distortion Corr. Prescan Normalize Normalize Raw filter Elliptical filter Geometry Multi-slice mode Series Saturation mode Special sat. Set-n-Go Protocol Inline Composing System Body HE2 HE4 HE1 HE3 SP4 SP2 SP8 SP6 SP3 SP1 SP7 SP5 H 0 mm Positioning mode MSMA Save uncombined Coil Combine Mode Auto Coil Select REF S - C - T Sum of Squares Default Shim mode Adjust with body coil Confirm freq. adjustment Assume Silicone Ref. amplitude 1H 205.057 V Adjustment Tolerance Auto Adjust volume 300 mm 300 mm Physio 1st Signal/Mode Segments 1 Tagging Dark blood Resp. control Inline Subtract Liver registration Std-Dev-Sag Std-Dev-Cor Std-Dev-Tra Std-Dev-Time 9/+

MIP-Sag MIP-Cor MIP-Tra MIP-Time Save original images Wash - In Wash - Out TTP PEI MIP - time Sequence Introduction Dimension 3D Elliptical scanning Phase stabilisation Asymmetric echo Contrasts 1 Bandwidth 980 Hz/Px Flow comp. No RF pulse type Gradient mode Excitation RF spoiling Non-sel. 10/+

\\USER\INVESTIGATORS\Ravi\ADNI-Subject\Axial PD-T2 TSE TA: 6:50 PAT: Voxel size: 0.9 0.9 3.0 mm Rel. SNR: 1.00 SIEMENS: tse Properties Prio Recon Before measurement After measurement Load to viewer Inline movie Auto store images Load to stamp segments Load images to graphic segments Auto open inline display AutoAlign Spine Start measurement without further preparation Wait for user to start Start measurements single Routine Slice group 1 Slices 48 Dist. factor 0 % Position L0.9 A20.9 H8.2 9 Phase oversampling 0 % FoV read FoV phase 89.1 % Slice thickness 3.0 mm TR 3000 ms TE 1 12 ms TE 2 97 ms Averages 1 Concatenations 4 Filter Prescan Normalize, Elliptical filter Coil elements HE1-4 Contrast TD MTC Magn. preparation Flip angle Fat suppr. Fat sat. mode Water suppr. Restore magn. 0.0 ms 150 deg Strong Averaging mode Long term Reconstruction Magnitude Measurements 1 Multiple series Resolution Base resolution 256 Phase resolution 100 % Phase partial Fourier Trajectory Cartesian Interpolation PAT mode Matrix Coil Mode Auto (CP) Distortion Corr. Unfiltered images Prescan Normalize Normalize Raw filter Elliptical filter Mode Geometry Multi-slice mode Series Inplane Special sat. Set-n-Go Protocol Inline Composing System Body HE2 HE4 HE1 HE3 SP4 SP2 SP8 SP6 SP3 SP1 SP7 SP5 H 0 mm Positioning mode MSMA Save uncombined Coil Combine Mode Auto Coil Select REF S - C - T Sum of Squares Default Shim mode Adjust with body coil Confirm freq. adjustment Assume Silicone Ref. amplitude 1H 205.057 V Adjustment Tolerance Auto Adjust volume Position L0.9 A20.9 H8.2 9 214 mm 144 mm Physio 1st Signal/Mode Dark blood Resp. control Inline Subtract Std-Dev-Sag Std-Dev-Cor Std-Dev-Tra Std-Dev-Time MIP-Sag 11/+

MIP-Cor MIP-Tra MIP-Time Save original images Sequence Introduction Dimension 2D Compensate T2 decay Reduce Motion Sens. Contrasts 2 Bandwidth 163 Hz/Px Flow comp. No Allowed delay 30 s Echo spacing 12.1 ms Define Turbo factor Turbo factor 7 Echo trains per slice 33 RF pulse type Low SAR Gradient mode Normal 12/+

Table of contents \\USER INVESTIGATORS Ravi ADNI-Subject Localizer MPRAGE MPRAGE Repeat B1-calibration Head Turn Body Coil on. B1-calibration Body Turn Head Coil Array on. Axial PD-T2 TSE 13/-