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This tutorial will teach you how to utilize every aspect of PEPID Clinical Rotation Companion and is organized by the tool bar at the top of the online application. At the end, you will find a quiz, which will prepare you to quickly and efficiently navigate through PEPID CRC. >> Table of Contents The Table of Contents (TOC) icon allows you to see all that is offered on your PEPID Clinical Rotation Companion Suite. With the >> Back The Table of Contents, you select from a thematic listing of topics as shown below: How to use PEPID What s New Basic Principles Clinical Rotations Drug Database Interactions Generator Medical Calculators Illustrations Lab Manual Warning Back icon takes you to the previous screen. The Back icon can always be found in the tool bar at the top of the screen. If you click a link to view a subtopic, you can use the Back icon to return to the same place on the previous screen. >>Top If you have scrolled down the page on any topic, the Clinical Rotation Companion Tutorial: Online Top icon will direct you to the top of that page.

2 >>Home The home icon takes you to the PEPID index, which is essentially your search tool for PEPID. The index icon allows you search for anything within our content, whether it s a disease, drug name, medical calculator, lab or procedure. To Use: 1. Click the Home Index icon in the navigation bar. 2. Type in the letters of the topic you want to search, like Vtach, for example. Vtach uses every feature of PEPID. 3. Tap Vtach in the listing menu. 4. From the Ventricular Tachycardia (Vtach) page, you can click on the Quicklinks Menu icon to view related topics, including Diagnosis and Pathophysiology. Tap CLOSE- to return. 5. From the Vtach page, you can click on the Camera icon to view Monomorphic and Polymorphic rates. Click the Back icon to return. 6. On the Vtach page, use the right scroll bar to go down the page. Click vagal maneuvers to view more details. You will see these glossary links throughout the application. Click the Back icon to return. 7. Continue to scroll down the Vtach page, and you will come across relevant calculators. You can click on the Qt int to view the QT Interval Correction equation, or you can click the Medical Calculator on the screen next to the Qt int link to actually use the calculator. Click the Back icon to return. 8. Continue to scroll down the Vtach page, and click on the Amiodarone link. From the quicklinks menu, you can view dosing, kinetics, IV info, overdose management, etc. Scroll down and tap on any of the IV Drip Rate icons to use the calculator. Notes: The fastest way to find any topic Links directly to the index Use keypad or graffiti area to enter first few letters Tap entry to select from alphabetical keywords list Use scrollbar to navigate complete list Alphabetical index is colorized for distinction Drug topics are blue Tables of contents are bolded Chapter headings are bolded and capitalized To go to the Table of Contents, find it in the top listing, or enter either TOC or a period (.) in graffiti area between keywords 2

>> Laboratory Manual PEPID s lab manual provides critical values and normal ranges for common lab tests. The {Lab Test TOC} link located top right, links you to a thematic arrangement of lab tests. Lists conditions and medications associated with atypical levels of measured factors Contains links to related medical calculators and lab tests >> Medical Calculators The medical calculator icon allows you to view the alphabetically organized medical calculator index and links you to the medical calculator table of contents. The {Medical Calculator TOC} link located top right, links you to a thematic arrangement of calculators. To Use: 1. Click the medical calculator icon in the menu bar. 2. Click on the first letter of the desired calculator. 3. Select the underlined text to view equation for specified calculation. 4. Click on the medical calculator on the screen. 5. Input data using your keyboard. 6. Click on the Results button to view the answer. Example: Calculate the Body Mass Index of a 5 7 female weighing 150 lbs. Result: 23.525 kg/sq.m. It also 3 tells you that the normal range is 23-27 kg/sq.m.

>> Differential Diagnosis Generator (DDX) How to Use: Select the DDX icon in the top menu bar. - DDX will open in the Quicklinks Menu, on the right side of the screen. - To change HPTs filters [Symptoms (History), Signs (Physical Exam), Tests (T)], check and/or uncheck the filter options at the top of the DDX screen. To Search for Symptoms: - Type symptom(s) in the Search toolbar, and then click the symptom to select it. The selected symptom will be highlighted in yellow. Repeat for all symptoms. - To de-select a symptom, click the symptom again and the highlight will disappear. - If the selected symptom has any sub-symptoms, the sub-symptoms options will appear. (To choose the sub-symptoms, check the box next to the sub-symptoms) - Once you have selected all the symptoms, click the Find DDX button. Diagnosis Results: - The Symptoms you selected will appear at the top of the screen under Selected Symptoms. - To change the filters for Gender, Age Group, Severity, Etiology and Onset, click the arrow next to Specify Filters and use the drop-down menus to change the filters. - The conditions associated with the selected symptoms will be listed and rated on a scale from 1 to 5, 5 being the most likely diagnosis. - Scroll over the symptom s numerical rating to see which of the symptoms are related to that diagnosis. The symptoms that are related will turn to bold under the Selected Symptoms list at the top of the screen. - To find out more about any specific diagnosis, click the diagnosis text for more information in the middle column. * Available in CRC Platinum or as a product enhancement. 4

>> Quick Reference The Quick Reference icon is the best way to view abbreviations list, glossary, procedures, illustrations, etc. clinical rotation companion tutorial 4 With the Quick Reference you can view a thematic listing of the following topics: 1. How To Use PEPID 2. What s New in PEPID 3. Table of Contents 4. Abbreviations 5. Glossary/Eponyms 6. Street Drug Names 7. Normal Lab Values 8. Stedman s Dictionary 9. Procedures 10. Illustrations 11. Why PEPID 12. Authors >> Drug Interactions Generator The drug interactions generator icon allows you to select up to 50 different drugs, herbals, OTCs and supplements and cross reference their interactions. The drug interactions generator will appear in the right column. 5

To Use: 1. Select the drug interaction icon in the tool bar. 2. In the right column, click Dig Tool. 3. Use your keyboard to enter the first three letters of a drug. 4. Click individual selections (up to 50 drugs, herbals or foods). 5. Click the Done button after all selections are made. If you need to remove any of the selections, click the box in front of the drug. 6. Click the Interactions Button. The drug interactions generator checks interactions between each subject drug and all of the other drugs you have selected. Non-subject drugs are not compared against each other. Notes: Numbers represent severity of interaction: 1 = low, 5 = high Interactions are listed by decreasing severity When there are multiple interactions between two drugs, the strongest in severeity will be in bold Other interactions of same group listed in regular type Indicates drug level or effect of the following drug will be increased Indicates drug level or effect of the following drug will be decreased Indicates drug level or effect of the following drug will be either increased or decreased ATC: anticoagulation Click any underlined text for more information Example: Cross reference the following drugs: Amiodarone, Biaxin, Coumadin, and Ginger. Pepid found seven drug interactions. Click on interaction to view details. Three results are listed below: 5- QT:Amiodarone, Biaxin-Both increases QT s, never use combination 3- Amiodarone, Coumadin-Amiodarone increases levels and effects of Coumadin. Possible serious or lifethreatening interaction 3- Coumadin, Ginger-Both are anticoagulants-potential danger 6

>> Acute Care Reference The Acute Care Reference provides links to immediate life saving protocols: BLS, ACLS, ATLS, PALS, RSI, procedures, algorithms, quick drugs and drips, etc. The {TOC} Table of Contents Link located top right, links you to a broader range of topics. clinical rotation companion tutorial 6 With the Acute Care Reference you select topics from a thematic listing as shown below: 1. Life Support 2. Airway Support 3. Acute Care Procedures 4. Medical Status 5. Shock Types 6. Other 7. Authors >> Notes The notes icon allows you to create, edit, and delete notes. Once a note is created, anytime a subject that has a note is searched for, there will be an alert in the Quicklinks Menu in the right column. To Use: 1. From the Acute Care Reference, under Shock Types, select Cardiogenic Shock. 2. Click the Notes icon to add a note. 3. In the right column, click Add New Note. 4. Enter a title in the space provided. 5. Type in the note in the space provided. 6. Click the Save Note button. Note: The next time you search for the Cardiogenic Shock topic, there will be a line in the right column that reads, You have personal notes for this page. Click here to view them. 7

>>Quicklinks Menu The Quicklinks Menu brings up any subtopics in the right hand column. If you click on any of the subtopics in the Quicklinks Menu it will bring you to that subject in the middle column. The Quicklinks Menu will appear only when subtopics are available. clinical rotation companion tutorial The Quicklinks Menu allows you to: Access subtopic navigation menu when applicable Display Quicklink menu in the right column Select from list to link directly to subtopic >>Other Links The camera icon takes you to all related images, including original high-resolution color illustrations that are great for patient education or personal reference. Our illustration include clinical anatomy, rhythm strips, procedures, environmental, toxicologic and diseases and disorders The IV Drip Rate icon takes you to all available related IV Drip Rate Calculators. {Rel. Topic} The Related Topic link takes you to broader topics related to the current page. [Tx] The Treatment link allows you to view related treatments. E B The Evidence Based link allows you to view all Clinical Inquiries by FPIN, Family Physicians Inquiries Network. TM This is an exclusive feature to PEPID applications. This icon indicates a Stedman s term is integrated, simply click to read the definition of the term. 8

Clinical Rotation Companion TEST 1) What is easiest way to locate a specific item in PEPID CRC Online? a) Index b) Table of Contents c) Quick Links d) Quick Reference (Question Mark) e) None of the above 2) What does the abbreviation LAD stand for? a) Left Anterior Descending b) Left Axis Deviation c) Lymphadenopathy d) All of the above e) None of the above 3) How many types of Salter Harris fractures are listed in the Clinical Anatomy section? a) 6 b) 7 c) 5 d) 2 e) 4 4) Premature Atrial Contraction is a type of which of the following? a) Congestive Heart Failure b) Heart Blockage c) Premature Labor d) Irregular Heart Beat e) None of the Above 9

10 5) Which of the following drug combinations should not be used if at all avoidable? a) Kanamycin and Selenium b) Medrol and Penicillin c) Baridium and Teicoplanin d) Teicoplanin and Kanamycin e) None of the above 6) Which of the following drugs should never be used with the Varicella Virus Vaccine? a) Salicyclic Acid b) Nalidixic Acid c) Paclitaxel d) Desloratadine e) Aripiprazole 7) Under Clinical Rotations, how many subtopics are in the Surgery section? a) 5 b) 9 c) 16 d) 14 e) 10 8) How much Hydromorphone do you have to give to a patient to equal the strength of 0.5 mcg of Buprenorphine? a) 0.0045 mg b) 0.0025 mg c) 0.025 mg d) 0.045 mg e) None of the above 9) The Extra Cellular Fluid equation is a part of which class of Medical Calculator? a) Body Mass Index b) Body Weight, Ideal c) Body Water, Total d) Body Weight, Adjusted e) All of the above 10

10) What is not an indication of Ventilator Management (Basic Principles section)? a) Ventilatory Failure b) Oxygenation Failure c) Mechanical Failure d) Vital Capacity e) Positive End Expiratory Pressure 11) Which of the following is not an adverse drug reaction to Accutane? a) Cheilitis b) Thinning hair c) Hypertriglyceridemia d) All of the above e) None of the above 12) How many different dosing options are there in the renal impairment section in administering Milrinone? a) 5 b) 2 c) 7 d) 6 e) 3 13) What condition does Auspitz s sign suggest? a) Blowfish Poisoning b) HELLP Syndrome c) Psoriasis d) Reiter s Syndrome e) Onychomycosis 14) Which of the following is not a caution when administering Milrinone? a) Atrial fib/flutter b) Electrolyte abnormalities c) Short-term use only d) Antidepressants e) Abnormal electrolytes 11

12 15) Which type of Salter-Harris fracture crosses through the epiphyseal plate? a) Type I, S b) Type II, A c) Type III, L d) Type IV, T e) Type V, ER 16) What is the easiest way to get to the Glossary in PEPID? a) Quick Reference Icon b) Home Index Icon c) Quicklinks Menu d) All of the above e) None of the above 17) What is the first step in administering Milrinone? a) 50 mcg/kg IV over 20 minutes b) 60 mcg/kg IV over 20 minutes c) 65 mcg/kg IV over 10 minutes d) 60 mcg/kg IV over 10 minutes e) 50 mcg/kg IV over 10 minutes 18) Which of the following is not listed under the Neurology Pearls section? a) HTN b) Migraine c) Cluster HA d) Meningitis e) Encephalitis 19) What should the IV drip rate be to achieve a dose of 1 mg/min Amiodarone in an adult, with a 1.8 mg/ml solution? a) 30.55 ml/hr b) 25.65 ml/hr c) 33.33 ml/hr d) 20.33 ml/hr e) 27.15 ml/hr 12

20) Which of the following is not a medical cause of low bicarbonate levels in the blood? a) Compensated respiratory alkalosis clinical rotation companion tutorial b) Diabetes mellitus c) Cholestyramine, cyclosporin A d) Diarrhea e) Metabolic acidosis Answers Answers Key: 1) a 2) d 3) c 4) d 5) d 6) a 7) d 8) b 9) c 10) e 11) e 12) d 13) c 14) d 15) d 16) a 17) e 18) a 19) c 20) c 13