The de.nbi network a dynamic and distributed infrastructure for bioinformatics in Germany

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The de.nbi network a dynamic and distributed infrastructure for bioinformatics in Germany A. Pühler de.nbi coordinator Center for Biotechnology Bielefeld University Kolloquium der Universitätsbibliothek am 15. Dezember 2017 in L3-108, Universität Bielefeld 15.12.2017 1

The de.nbi network a dynamic and distributed infrastructure Outline Organization and governance structure of the de.nbi network mission statement organizational chart central coordination unit specialinterest groups Initial tasks of the de.nbi network services and tools training and education communication Additional tasks of the de.nbi network partner projects ELIXIR cooperation de.nbi cloud Future tasks of the de.nbi network industrial branch sustainable continuation 2

Organization and governance structure of the de.nbi network Mission statement and timeline of the de.nbi project Mission statement The 'German Network for Bioinformatics Infrastructure' provides comprehensive first-class bioinformatics services to users in basic and applied life sciences research. The de.nbi program coordinates bioinformatics training and education in Germany and the cooperation of the German bioinformatics community with international bioinformatics network structures. 3

Organization and governance structure of the de.nbi network CCU members CAU members SAB members 4

Organization and governance structure of the de.nbi network Overview on de.nbi Service Centers and Special Interest Groups HD-HuB, Heidelberg Bioinformatics Infrastructures in Biomedical Research BioInfra.Prot, Bochum Bioinformatics for Proteomics RBC, Freiburg RNA Bioinformatics de.nbi-sysbio, Heidelberg Standards-based Systems Biology BiGi, Bielefeld MicrobialResearch for Biotechnology and Medicine GCBN, Gatersleben Crops and BioGreenFormatics CIBI, Tübingen Tools for omics data and imaging BioData, Bremen Reference Databases, Services and Tools The Special Interest Groups (SIGs) of the de.nbi network, and their chairpersons (status 04/2017) SIG Title Chair SIG 1 SIG 2 SIG 3 SIG 4 SIG 5 SIG 6 SIG 7 Communication and outreach Service and service monitoring Training and education Infrastructure and data management de.nbi development de.nbi cloud ELIXIR cooperation J. Stoye, F. Sprengel F. O. Glöckner, U. Scholz O. Kohlbacher, D. Wibberg M. Eisenacher, W. Müller A. Pühler, U. Kummer C. Lawerenz, A. Sczyrba A. Goesmann, H. Gundlach 5

Initial tasks of the de.nbi network Services and tools offered by de.nbi Summary of tools offered by the eight service centers: 115 services are listed on the de.nbi web page ~ 100 services are registered in the 'BioTools' registry hosted by ELIXIR 76 services are announced to be monitored using the tool 'SurveyMonkey' 35 flagship services were offered to ELIXIR 6

Initial tasks of the de.nbi network Training and education carried out by de.nbi Summary on training courses: 2015 2016 2017 training courses 17 40 68 participants 329 882 1,500 Summary on summer schools: Microbial Bioinformatics, September 2015 in Gießen From Big Data to Big Insights, September 2016 at Schloß Dagstuhl, Wadern Cloud Computing for Bioinformatics, June/July 2017 in Gießen Computational genomics and RNA biology, September 2017 in Berlin Galaxy Workshop on HTS data analysis, 2016 in Freiburg de.nbi Summer School 2016 at Schloß Dagstuhl, Wadern 7

Initial tasks of the de.nbi network Communication activities of de.nbi In order to reach users and also de.nbi members, communication plays an important role. This includes the following projects: The de.nbi web page The de.nbi Twitter channel The de.nbi Youtube channel The de.nbi Flyer The de.nbi Quarterly Newsletter The de.nbi Handbook General articles A special issue of the Journal of Biotechnology 23.11.2017 8

Additional tasks of the de.nbi network Integration of partner projects into the de.nbi network In order to close scientific gaps in the de.nbi network, a BMBF call for partner projects was launched in November 2015. An international reviewer panel finally selected eight joint projects with altogether 16 partners which became active 1 November 2016. The eight partner projects cover the following topics and were incorporated into the existing service centers: Project / Service Center Topic Project / Service Center Topic LIFS / BioInfra.Prot lipidomics NBI-ModSim / de.nbi-sysbio modelling MASH / CIBI metabolomics DAIS / CIBI image analysis Enzyme structure / BioData structural biology de.nbi-epi / HD-HuB and RBC epigenetics de.stair / RBC RNA sequences MetaProtServ / BiGi metaproteomics 9

Additional tasks of the de.nbi network The collaboration with ELIXIR August 2016: BMBF signed the ELIXIR Consortium Agreement to establish ELIXIR Germany. ELIXIR Germany is run by the socalled German ELIXIR Team. As a next step, the German Node Application was established, proposing that the initial de.nbi projects contribute to the German ELIXIR node. A further document, the Collaboration Agreement, is not yet signed. ELIXIR Germany is already involved in many ELIXIR activities like Implementation Studies, ELIXIR Core Data Resources, and ELIXIR Use Cases. The German ELIXIR Team Head of Node: Deputy: Technical coordinator: Deputy: Training coordinator: Deputy: Members of the ELIXIR Board Prof. Dr. A. Pühler Prof. Dr. A. Tauch Prof. Dr. R. Backofen Dr. B. Grüning Prof. Dr. O. Kohlbacher Dr. D. Wibberg Prof. Dr. R. Eils Prof. Dr. A. Goesmann Dr. J. Mohr, BMBF 10

Additional tasks of the de.nbi network Establishment of a de.nbi cloud In July 2016, BMBF provided 6 Mio EURO and 6 scientific positions to start the establishment of a compute component of the de.nbi cloud. The Universities located in Bielefeld, Gießen, Freiburg, Heidelberg and Tübingen were selected to participate in the federated cloud project. In July 2017, BMBF provided again 6 Mio EURO to add a storage component to the de.nbi cloud. The people responsible for the de.nbi cloud in Bielefeld are S. Albaum and A. Sczyrba. 11

Future aspects of the de.nbi network The role of de.nbi for the future of life sciences In Germany, an established bioinformatics infrastructure is crucial for further development of life sciences. In Germany, de.nbi forms and should form the basis for the national node in ELIXIR. It has to be concluded that de.nbi is an essential infrastructure which has to be maintained in future. 12

Future aspects of the de.nbi network Model for the sustainable continuation of the de.nbi network Integration into one of the steadily financed BMBF organizations such as Helmholtz Association or Leibniz Association. Implementation of a new funding structure for dynamic and distributed infrastructures by BMBF. 13

The de.nbi network a dynamic and distributed infrastructure Summary of the presentation Vision The de.nbi network a dynamic and distributed infrastructure should become one ofthe most powerful national bioinformatics infrastructures in Europe. Achievements Establishment of service and training activities Incorporation of de.nbi as a national node into ELIXIR Establishment of a de.nbi specific cloud at five universities Future activities Development of a marketing concept for the de.nbi network Establishment of an industrial branch of de.nbi Development of a plan for the sustainable continuation of the de.nbi initiative 14

The de.nbi network a dynamic and distributed infrastructure Many thanks for your attention! The plenary meeting of the de.nbi network at Bielefeld University in October 2017 QUESTIONS? 15