24, rue du champ de l Alouette F 75013 Paris, France Venus Explorer Processing Technical specifications Venus Explorer Processing Server software Web base application sever; tomcat Apache technology. Include Dicom server and MySQL database management. Venus Explorer Processing Server Venus Explorer Processing software Venus Explorer Processing is a null client installation and a navigator is used to access to the applications. Venus Explorer Processing Client licences are floating (concurrent); allow the software to be loaded on multiple PC s for concurrent user login. Some third party options (i.e. Cedars) are either fixed (node-locked) or floating (concurrent). Fixed Client licence is node-locked to a certain IP address on the network. Floating Client licence provides access from any Windows PC on the network (with compatible graphic board & memory) and concurrent access is only limited by the number of Venus Explorer Processing Client licences purchased. Venus Explorer Processing - run on any hardware (PC, MAC, ); the process is done an application server; client access through a web navigator. 24 rue du champ de l Alouette - 75013 Paris - France - RCS PARIS B 418 126 710 5 98B04764 Tel: +33.1.53.62.24.00. Fax:+33.1.53.62.00.10.
Venus Processing NUCLEAR MEDICINE, PET/SPECT/CT/MR MULTIMODALITY IMAGING SOLUTIONS CONSISTENCY Uniform reading and processing environment for all your SPECT and PET cameras. With Venus Explorer Processing, you are no longer bound to a particular camera workstation. Venus Explorer Processing gives you complete functionality to process or review all NM scans regardless of camera vendor, using a suitable PC with secure access to the department server. CLINICALLY SUPERIOR Delivers the full spectrum of clinical NM and multi-modality applications Dedicated to deliver advance co-registration fusion, multimodality viewing and quantification specialized tools. Delivers a unique PET/SPECT/CT/MR multi-modality viewer completely operator configurable with advanced Tumor tracking feature. nicesoft endless continues its cooperation with leading worldwide medical institutions in order to provide you with the most complete, state of the art, while innovative multimodality clinical software library able to meet your needs. CUSTOMIZABLE, FLEXIBLE & SECURE Easy to used interactivity: Venus Explorer Processing scales its functionality to the expert level of the user based on logon credentials. Venus Explorer Processing provides the full flexibility to expert users and limits the available functionality to the occasional user, keeping the system simple enough for those users and avoiding misinterpretations due to the operator error. Use processing and display scripts and supply a powerful user preference mechanism to control them. Venus Explorer Processing uses processing and display scripts and supply a user preference mechanism to control them; permits a customization of display pages through a of lay-out editor which permits to change, resize, delete or create display objects. Easy to develop and maintain through modularization. Incorporate mechanism to create graphic layout. Highly display-centric; enhance 3-D displays, cine and curves. Numerous user interactions to display. Message and dialogue displays. Multiple monitor configuration: possible use of multi-screens, each screen being able to display a different page. Multiple resolutions for the monitors handled Unique use of screen - all formats. 2
Monitors Venus Explorer Processing workstations can be configured with different size monitors, accepting any screen resolution, in particular 16x9 formats, and multiple screen configurations; can come with single, dual, triple, quad or other multi-monitor configurations (up to 8 monitors) in order to best fit with your needs. Venus Explorer Processing software library comes with multi-monitor synchronization for easy review of multiple modalities or serial studies. Facilitates port to other vendors environnent. Venus Explorer Processing Offers the possibility of Floating Client software licenses. Venus Explorer Processing Client license allows access on the Venus Explorer Processing server & Venus Explorer Processing applications. Venus Explorer Processing Client licences are floating (concurrent). Some third party options (i.e. Cedars) are either fixed (node-locked) or floating (concurrent). SPECIALIZED Venus Explorer Processing specializes in customized, turnkey Nuclear Medicine, SPECT/PET/CT/MR and multimodality imaging solutions including seamless connectivity, uniform processing platform, multi-format archiving & remote reading distribution. CUSTOMER FOCUSED All Venus Explorer Processing software can be tailored to meet specific Nuclear Medicine and SPECT/PET/CT/ MR department needs. NICESOFT features personalized onsite and remote customer support to assist & support you quickly & efficiently. EFFICIENT ARCHITECTURE The Venus Explorer Processing Client/Server architecture provides an efficient infrastructure for data and application management. Allows remote-access The Venus Explorer Processing data architecture is very much like a PACS system as it deploys a redundant central database for all NM data. Venus Explorer Processing is fully DICOM compliant and integrates non-dicom compliant sources through an optional system. Use sophisticated DICOM library; include Cardio (EKG, etc.) Expandable: Venus Explorer Processing is the first system of its kind that provides you completely expendable application delivery architecture no matter what the future may hold. COST EFFECTIVE Client runs on standard PC hardware. Applications reside on the server side and are very fast downloaded to the client when needed. Processing is performed on the client. Each clinical application can be licensed separately which means you only pay for the software you really need. Also, it allows you to start with Venus Explorer Processing with a minimum investment and add more users and capabilities over time. 3
PACS COMPATIBLE Designed as the NM complement of modern PACS systems with integration support for legacy cameras and data formats. OPEN Allows for tight integration of common third party applications (e-g: cardiology - Cedars / Emory / 4DMSPECT Michigan). BLAZINGLY FAST The Venus Explorer Processing display engine capitalizes on the extreme processing power available in modern graphics cards: the utilization of GPU for display and computations maximizes performance while reducing CPU loads (processing on client stations). Venus Explorer Processing architecture utilizes the available power of OpenGL to the fullest extend. The result is immediately obvious as the display interactions on large datasets and 3D renderings are blazingly fast. Offers an instant access to data loaded from PACS & server. NON OBSOLESCENCE Fully protected against future changes in instrumentation. VENDOR NEUTRAL Venus Explorer Processing is a vendor-neutral multimodality processing & multimodality platform for Nuclear Medicine which maintains data integrity across all vendor platforms, providing you with all freedom of choice for new cameras & PET/CT scanners purchases. QUALITY DRIVEN All Venus Explorer Processing software library is CE Mark (Europe). Venus Explorer Processing complies with HIPAA, EU privacy laws. NICESOFT is ISO & CMRD certified. VALIDATED Venus Explorer Processing software library & applications are validated & tested and have been used clinically for part of the software library since 1998. 4
General Clinical Applications Venus Processing Functional specifications General NM Viewer Generic viewer for NM images in static, dynamic, wholebody, or planar gated format and secondary captures from all modalities. Display functions: window leveling, color scale selection, zoom, pan, magnify, colorize Measurement tool Independent or synchronized window leveling SPECT-CT (multimodality viewing) Clinical application for review and analysis of SPECT/CT studies. Standardized orthogonal slice displays Display functions: triangulation, window leveling, color scale selection, slice alignment, cine controls, zoom, pan, magnify, colorize Measurement tool User definable CT window presets Distance weighted maximum intensity projections (MIP) Fusion display mode based on variable alpha blending and/or variable thresholding Manual registration adjustment (translations, rotations) 3D region analysis based on iso-contouring Study comparison (follow-up) 5
User definable hotkeys for commonly used functions Dedicated Lesion, Linking, and Registration Managers User specific preferences based on logon credentials Compatible with all SPECT and hybrid SPECT/CT scanner models Customized layouts through display scripts Volume rendering option Volume rendering generation. 6
PET-CT-Onco (multimodality viewing) Clinical application for review and analysis of PET/CT studies. Standardized orthogonal slice displays Display functions: triangulation, window leveling, color scale selection, slice alignment, cine controls, zoom, pan, magnify, colorize Measurement tool Automatic window saturation function for PET User definable CT window presets SUV computation Distance weighted maximum intensity projections (MIP) Fusion display mode based on variable alpha blending and/or variable thresholding Manual registration adjustment (translations, rotations) Tumor-tracking analysis using auto 3D lesion contouring Study comparison (follow-up) with automatic rigid CT/CT registration User definable hotkeys for commonly used functions Dedicated Lesion, Linking, and Registration Managers Export of to RT systems User specific preferences based on logon credentials Compatible with all PET and hybrid PET/CT scanner models Customized layouts through display scripts 7
Bones Clinical application for review and analysis of bone scintigraphy studies. Combined display of Static, Dynamic, WB, and SPECT images Display functions: triangulation, window leveling, color scale selection, slice alignment, cine controls, zoom, pan, magnify, colorize Measurement tool Bladder masking tool Region of interest analysis (ROI) 3-phase bone analysis Distance weighted maximum intensity projections (MIP) User definable hotkeys for commonly used functions User specific preferences based on logon credentials Customized layouts through display scripts 8
Gastric Reflux Clinical application for review and analysis of gastric reflux stimulation studies. Manual ROI definition Time activity curve analysis Compatible with dynamically acquired datasets User specific preferences based on logon credentials Customized layouts through display scripts Gastric Emptying Clinical application for review and analysis of gastric emptying studies. Analysis of stomach function Separate analysis of solid and liquid phase Compatible with dynamic or multiple static data Analysis of dynamic esophageal function Customized layouts through display scripts 9
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Sentinel Node Display of two static images with a specialized gray scale optimized for the high maximum counts typical in sentinel node imaging. Thyroid and Parathyroid Clinical application for review and analysis of thyroid uptake, thyroid and parathyroid studies. Uptake calculation based on pre/post injection dose image Relative R/L lobe uptake Either technetium or iodine studies Fusion of marker and anterior thyroid images Subtraction analysis of dual isotope (Tc, Tl) parathyroid studies Dual phase (Sestamibi) parathyroid studies 11
Renal Clinical applications for review and analysis of renography studies. Analysis of kidney function Auto region of interest with manual override Time activity curve analysis Split function Measurement tool Compatible with Tc-99m-DTPA, Tc99m-MAG3 Multi-phase analysis Separate applications for handling of Anterior, Transplant and Single Kidney scenarios. 12
VenusCardiac Clinical application for reconstruction, processing and display of gated and ungated tomographic cardiac data. Access to optional Cedars MoCo motion correction module for the automatic and manual correction of SPECT acquisition motion artifacts. Pattern matching and segmentation algorithms are used in conjunction to minimize motion error metrics over the set of acquired projections; the resulting motion corrected projections are then presented to the operator for validation or modification. Reorientation, zooming and masking of reconstructed data. Slice review displays Direct access to quantification with third party applications such as Cedars Sinai QGS-QPS etc. MUGA Clinical application for review and analysis of planar gated blood pool studies. Automatic segmentation of left ventricle (ED, ES, and background ROI, with manual override) Unique Fourier based filtering technique for improved visualization of wall motion Display functions: window leveling, color scale selection, slice alignment, cine controls, zoom, pan, magnify Amplitude/Phase analysis 16
Pseudo3D cine display (topographic dynamic mapping of counts) Multi-study comparison (multiple exercise levels, or follow-up) Right ventricle processing options (RVEF, RV volumes) Compatible with most acquisition protocols (matrix size, #frames/cycle) Customized layouts through display scripts Planar Lung Analysis Clinical application for review and analysis of planar lung studies. Analysis of Ventilation, Perfusion, or Ventilation + Perfusion Static image display of all acquired orientations Display functions: window leveling, color scale selection, zoom, pan, magnify, colorize Measurement tool Automatic 2-segmental quantification of anterior and posterior images ; Generation of geometric mean images User definable hotkeys for commonly used functions User specific preferences based on logon credentials 17
LungSPECT-CT An application for reconstruction, display and linked triangulation of ventilation and perfusion SPECT studies. Includes creation of reprojection images and MIRegistration of perfusion and ventilation series. 18
Utilities MIRegister A clinical application that provides direct access to the Mutual Image Information Registration utilities. Automatic process & manual adjustments 19