CryoClear. Cryogenic Vials. Innovation. for the long-term storage of your precious samples.

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CryoClear Cryogenic Vials Innovation for the long-term storage of your precious samples.

CryoClear Cryogenic Vials Innovation to protect your precious samples. Globe Scientific s CryoClear vials are designed for the cryogenic storage and transport of biological specimens at temperatures as low as -196ºC. The vials feature an innovative screw cap that is co-molded with a layer of thermoplastic elastomer (TPE). This special process provides the leak-proof benefits of an o-ring, while eliminating the risk of contamination and sample loss associated with the use of separate o-rings. Each vial is printed with a unique barcode that may be used for automated data collection, accurate sample inventory or to conceal the sample s identity. Purity Guaranteed: Manufactured, assembled and packaged in an ISO 7 (Class 10,000) cleanroom and never exposed to outside contaminants. Meets FDA, GMP and ISO Quality Standards. Lot certified: samples from every lot are shipped to an independent laboratory where they are certified to be Human DNA free, DNase free, RNase free, Pyrogen free and ATP free. Technical Details: Temperature range: -196º to 121ºC Autoclavable Sterilized by beta radiation (SAL 10-6 ) Pressure tested at 95 kpa (0.95 bar, 14 psi) CryoClear vials are available for purchase in bags of 50 vials and cases of 10 bags of 50 vials. Each bag of 50 vials is heavy-duty, tamper-proof and resealable. Material: Tube: Medical grade polypropylene (PP) Cap: Medical grade polyethylene (PE) co-molded with thermoplastic elastomer (TPE)

Innovation. Color coded inserts are available to fit both internal and external caps for quick sample identification Innovative screw caps are produced from medical grade polyethylene (PE) and are co-molded with a thermoplastic elastomer (TPE) to provide a 100% leak-proof seal Chemical resistant caps Vials and caps are autoclavable Produced from medical grade raw materials that will not discolor after re-sterilizing Printed graduations for accurate measurements Standard code 128 barcode on each vial includes human readable characters printed in both left and right hand orientation for easy readability by all users. White writing surface for specimen identification Chemical resistant polypropylene (PP) vial Available with round bottoms or self-standing Self-standing vials interlock in Globe workstations Our innovative screw caps eliminate leakage and contamination. CryoClear screw caps are co-molded with a thermoplastic elastomer (TPE) layer and are 95kPa certified to provide a 100% leak-proof seal. This proprietary molding process eliminates the risk of contamination associated with brands that use separate o-rings.

CryoClear Cryogenic Vials Internal Threaded Vials (shown actual size) Internal Thread Cap OD 12.50 mm Order Number 3001 3002 3003 3004 3005 3006 3008 Volume 1 ml 2 ml 2 ml 4 ml 4 ml 5 ml 5 ml Height* 42.7 mm 48.0 mm 47.0 mm 75.1 mm 76.1 mm 89.3 mm 90.4 mm Vial O.D. 12.5 mm 12.5 mm 12.5 mm 12.5 mm 12.5 mm 12.5 mm 12.5 mm Style Self standing Self standing -- -- Self standing -- Self standing Bottom Conical Round Round Round Round Round Round Packaging 500/case, 10 bags of 50 vials (Also sold by the bag of 50) *Height with caps attached. Tamper Evident, Resealable and Lot Traceable Packaging All CryoClear cryogenic vials are sold in heavy-duty, tamper evident resealable plastic bags. 50 vials per bag, 10 bags per case Heavy-duty, tamper evident resealable plastic bags Each bag labeled with manufacture date and barcoded lot number for traceability

External Threaded Vials (shown actual size) External Thread Cap OD 14.30 mm Order Number 3010 3011 3012 3013 3014 3015 Volume 1 ml 2 ml 2 ml 3 ml 4 ml 5 ml Height* 40.1 mm 44.5 mm 45.5 mm 69.3 mm 73.9 mm 88.1 mm Vial O.D. 12.5 mm 12.5 mm 12.5 mm 12.5 mm 12.5 mm 12.5 mm Style Self standing -- Self standing Self standing Self standing Self standing Bottom Conical Round Round Round Round Round Packaging 500/case, 10 bags of 50 vials (Also sold by the bag of 50) *Height with caps attached. Cap Inserts Cap inserts are available in assorted colors and are ideal for color coding and sample identification. The inserts snap easily into place on both internal and external caps. Polypropylene (PP) Ideal for color coding samples Item # Description Packaging Options 30075AST Assorted 6 x 100/bag 30075B Blue 100/bag & 1000/bag 30075G Green 100/bag & 1000/bag 30075P Pink 100/bag & 1000/bag 30075R Red 100/bag & 1000/bag 30075Y Yellow 100/bag & 1000/bag 30075W White 100/bag & 1000/bag

BioBox Plastic Storage Boxes Transparent lid for viewing contents Printed numerical grid for easy sample identification Each box features two angled corners to guarantee proper alignment of the grid Frosted writing area for smear-resistant marking Assorted colors for better color-coding BioBOX Storage Boxes with Transparent Lids Produced from polycarbonate (PC), these storage boxes are designed to withstand temperatures of -196 C to +121 C. The boxes are available in 25-place, 81-place and 100-place sizes and are available in assorted colors. Polycarbonate (PC) Temperature range: -196 C to +121 C Frosted writing area for smear-resistant marking Printed numerical grid for easy sample identification Transparent lid for viewing contents Each box features two angled corners to guarantee proper alignment of the grid Autoclavable at 121 C, 15 psig (1 bar) for 20 minutes Boxes have vent holes for drainage and rapid freezing Fits in stainless steel freezer racks A plastic vial picker (item #30078) is supplied with each BioBox BioBoxes for 1 & 2mL Vials Item # Description Dimensions (L x W x H) Unit 3039B 25-place (5x5), blue 76 x 76 x 52mm 8 3039G 25-place (5x5), green 76 x 76 x 52mm 8 3039R 25-place (5x5), red 76 x 76 x 52mm 8 3039Y 25-place (5x5), yellow 76 x 76 x 52mm 8 3040B 81-place (9x9), blue 132 x 132 x 52mm 5 3040G 81-place (9x9), green 132 x 132 x 52mm 5 3040R 81-place (9x9), red 132 x 132 x 52mm 5 3040Y 81-place (9x9), yellow 132 x 132 x 52mm 5 3050B 100-place (10x10), blue 132 x 132 x 52mm 5 3050G 100-place (10x10), green 132 x 132 x 52mm 5 3050R 100-place (10x10), red 132 x 132 x 52mm 5 3050W 100-place (10x10), white 132 x 132 x 52mm 5 3050Y 100-place (10x10), yellow 132 x 132 x 52mm 5 BioBoxes for 3, 4 & 5mL External & 5mL Internal Vials Item # Description Dimensions (L x W x H) Unit 3042B 81-place (9x9), blue 132 x 132 x 94mm 4 3042G 81-place (9x9), green 132 x 132 x 94mm 4 3042R 81-place (9x9), red 132 x 132 x 94mm 4 3042Y 81-place (9x9), yellow 132 x 132 x 94mm 4

Vial Picker/Storage Boxes/ Workstation Racks Vial Picker For the safe and convenient removal of frozen vials from storage boxes. Thermoplastic elastomer (TPE) Item # Color Unit 30078 Yellow Bag of 10 Cardboard Storage Boxes These economical boxes are designed for the long term storage of cryogenic vials in freezer rack systems. They have a liquid-resistant outer coating. Heavy-duty cardboard Temperature range: -196 C to +121 C Fits in stainless steel freezer racks Additional colors available by special order. Storage Box for 2" Tall Vials Dimensions: 134 x 134 x 47mm Item # Description Packaging Options 3090 64 place (8x8), white, for up to 2" tall x 15mm wide vials Each & 96/case 3091 81 place (9x9), white, for up to 2" tall x 13mm wide vials Each & 96/case 3092 100 place (10x10), white, for up to 2" tall x 12mm wide vials Each & 96/case Storage Box for 3" Tall Vials Dimensions: 134 x 134 x 76mm Item # Description Packaging Options 3094 64 place (8x8), white, for up to 3" tall x 15mm wide vials Each & 48/case 3094Y 64 place (8x8), yellow, for up to 3" tall x 15mm wide vials Each & 48/case 3095 81 place (9x9), white, for up to 3" tall x 13mm wide vials Each & 48/case 3096 100 place (10x10), white, for up to 3" tall x 12mm wide vials Each & 48/case Workstation Racks Globe workstations accommodate both round bottom and self-standing CryoClear cryogenic vials. The self-standing vials lock into the rack for easy one-handed opening and closing of caps. 40-Place (10 x 4 format) Polycarbonate (PC) Anti-slip rubber feet Autoclavable at 121 C, 15 psig (1 bar) for 20 minutes Temperature range: -196 C to +121 C Dimensions: 215 x 100 x 25mm Workstation Racks Item # Item # Color Unit 3049B Blue Each 3049G Green Each 3049R Red Each Anti-slip rubber feet hold workstation in place while removing caps Self-standing vials lock into workstation

Technical Specifications Material: Tube: Cap: Sterilization: SAL level: Autoclavable: Temperature range: Mold release agents: Maximum psi: Maximum centrifugation speed: Medical/FDA Polypropylene (PP) Medical/FDA Polyethylene (PE) co-molded with a thermoplastic elastomer (TPE) layer Beta radiation 10-6 Tubes and caps -196º to +121ºC None used in manufacturing 14.5 psi 17530 xg (To obtain RPM, verify the diameter of the centrifuge and convert) Technical Specifications/ Product Certifications For use in the vapor phase of liquid nitrogen. WARNING - DO NOT USE CRYOCLEAR VIALS IN THE LIQUID PHASE OF LIQUID NITROGEN. Product Certificatons Manufacturing environment: Material: CONEG: Sterilization: DNase, RNase and pyrogen free: Human DNA and ATP free: Non-cytotoxic: Non-hemolytic: In vitro Diagnostic Medical Device: Leak proof: IATA (International Air Transportation Association): Printing on the tubes is resistant to the following common laboratory chemicals: Isopropyl alcohol: 5-100% Butanol: 100% DMSO: 10-20% Bleach: 5% Acetic acid: 10% Hydrochloric acids: 10% NaOH: 10% Produced, assembled and packaged in a ISO 7 cleanroom (Class 10,000) in accordance with quality guidelines ISO 13485:2004, ISO 14644, ISO 14698 (Federal Standard 209), ISO 14000 and ISO 18000 Virgin raw materials are tested according to the United States Pharmacopia (USP) and with the drug master file (DMF) at the FDA, certified under USP Class VI This product meets CONEG requirements and therefore does not contain heavy metals in the color concentrate Sterilzed in accordance with EN ISO 11137 Every lot is certified* by an independent laboratory to be free of DNase, RNase and pyrogens Every lot is certified* by an independent laboratory to be free of Human DNA and ATP This product is certified* to be free of cytotoxins This product is certified* to be free of articles causing hemolysis Complies with Directive 98/79/EC of the European Parliament and the Council of 27 October 1998 on in vitro diagnostic medical devices Tubes are certified leak proof at a pressure of 95 kpa (0.95 bar, 14.5 psi) by applying a closure force of not less than 8 cnm Can be used as a primary receptacle for the transport of diagnostic specimens as outlined by the IATA Dangerous Goods Regulations, Part 6.3,5 *Certificate of Analysis available upon request. We Believe You Are Important How Can We Help? 800.345.2100 800.345.5232 fax PO Box 99 Swedesboro, NJ 08085 www.thomassci.com value@thomassci.com Copyright 2013 Globe Scientific Inc. All rights reserved. CyroClear and BIOBox are trademarks of Globe Scientific Inc. cryobro-th 1331