Surgipath Consumables Product Range

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1 Surgipath Consumables Product Range Order no.: English Rev A 08/2012 Copyright by Leica Biosystems Richmond, Inc. Illinois, USA, LEICA and the Leica Logo are registered trademarks of Leica Microsystems IR GmbH.

2 Contents Histology Solutions Histology Solutions Specimen Collection and Transfer Grossing Specimen Identification Cryosectioning Tissue Processing Embedding Paraffin Sectioning Routine Staining Staining/ Coverslipping Workstations Storage Solutions Contact Information Surgipath Consumables Product Range 01 Autopsy and Dissection Sectioning Blades Cassettes & Base Molds Cytology Mounting Media & Adhesives Paraffin Safety & Hygiene Slides & Coverglass Specimen Transport, Storage & Archiving Stains & Reagent Solutions

3 histology solutions 1 Histology Solutions Histology Solutions Help patients get accurate answers sooner. Leica Biosystems histology systems bring together instruments, consumables and expert advice covering the entire histology process. This integrated approach helps you deliver quality at each step, and enables increased efficiency throughout the entire workflow. Control costs, improve diagnostic clarity, increase speed: see how a Leica Biosystems solution can help you deliver better care to more patients, faster.

4 2 Leica Specimen Transport Products Specimen Collection and Transfer Histology starts the moment tissue is excised. To produce great slides, tissue needs to arrive in good condition. Each specimen must be carefully handled, correctly fixed, and transported as quickly as possible. Leica Biosystems specimen collection and transport products help ensure you receive the high quality samples you need.

5 histology solutions 3 Stains & Reagent Solutions: page 121 Specimen Transport, Storage & Archiving: page 111 Specimen Collection Solutions Securely transport and identify samples Choose the ideal fixative from Leica s wide product range Immediately start fixation to protect your sample

6 4 Leica Grossing Tools Grossing Tools for Fast, Accurate Grossing. Cut accurately, cut safely: grossing tools from Leica Biosystems help ensure consistent and uniform grossing. Choose the ideal solution for your laboratory.

7 histology solutions 5 Safety & Hygiene: page 93 Cassettes & Base Molds: page 51 Autopsy & Dissection: page 25 Grossing Solutions Accurately and efficiently dissect tissue and conduct autopsies Quickly complete even intricate work with the Surgipath range of ergonomic tools

8 6 Leica Printers & Leica Consumables Specimen Identification Specimen Identification is critical throughout the histology process. Leica consumables and instruments provide high-quality printing ensuring proper identification of the specimen throughout the entire histology workflow. The instrument and consumable pairing are designed to functionally work together for efficient laboratory productivity.

9 histology solutions 7 Leica IP S slide printer Leica IP C cassette printer Cassettes & Base Molds: page 51 Slides & Coverglass: page 101 Specimen Identification Solutions Save time fully automated printing with optional automatic unload station Reduce errors automated control and enhanced legibility reduce human error Choose a validated solution use Leica IP printers with our range of validated slides and cassettes (Surgipath Snowcoat Clipped Corner Slides and Leica IP Cassettes)

10 8 Leica Cryostats & Leica Consumables Cryosectioning For Everything New in Frozen Sections No matter what your sectioning requirements are, Leica Biosystems has the correct instrument, accessories and consumables for the best possible section. Because every patient needs the best care, make sure every frozen section is cut with a Leica cryostat and Leica consumables.

11 histology solutions 9 Leica CM1860/ CM1860 UV Cryostat Leica CM1520 Cryostat Leica CM1950 Platform Mounting Media & Adhesives: page 79 Sectioning Blades: page 43 Cryosectioning Solutions Safety advanced ergonomics plus innovations such as a waste removal system and UVC disinfection Efficiency high throughput and a choice of cryostats and consumables to match your ideal workflow Quality precise sectioning plus features such as CryoZone for consistency and quality

12 10 Leica Tissue Processors & Leica Consumables Tissue Processing Quality processing is the cornerstone of great histology. Protect patient tissue by using a reliable instrument plus optimized consumables for optimal tissue care. Leica Biosystems offers a diverse range of high-performance tissue processing products so you can find the optimal solution for high-quality processing in your laboratory.

13 histology solutions 11 Leica PELORIS II Leica ASP6025 Leica ASP300 S Cassettes & Base Molds: page 51 Paraffin: page 87 Stains & Reagent Solutions: page 121 Tissue Processing Solutions Protect patient tissue instrument reliability plus validated consumables for optimal tissue care Meet your quality standards quality comes first with Leica Biosystems Manage your workload tailor a solution that is ideal for your laboratory

14 12 Leica Embedding Instruments & Leica Consumables Embedding Great sections rely on careful embedding. Leica embedding solutions help you ensure correct tissue orientation, avoid heat damage, and create the ideal block shape. Setup a Leica embedding center to match your workflow, select base molds that match your cassettes, choose the ideal paraffin wax for your laboratory.

15 histology solutions 13 Leica EG1150 Leica EG F Paraffin: page 87 Cassettes & Base Molds: page 51 Autopsy & Dissection: page 25 Embedding Solutions Productivity highly flexible solutions with world-leading ergonomics Quality precise embedding stations plus high-quality consumables Safety ergonomics help reduce fatigue, repetitive strain injuries and human error

16 14 Leica Microtomes & Leica Consumables Paraffin Sectioning Precise Sections, All Day, Every Day. No matter what your sectioning requirements, Leica Biosystems has the ideal instruments, accessories and consumables. Combine a precise Leica microtome with high-quality Leica blades or knives and consistently cut high-quality sections.

17 histology solutions 15 Leica RM2125 RTS Leica RM2255 Leica SM2010 R Slides & Coverglass: page 101 Sectioning Blades: page 43 Paraffin Sectioning Solutions Precise accuracy and control for high-quality, reproducible sectioning Ergonomic innovative designs help you reduce fatigue and work comfortably all day Reliable robust microtomes yield unsurpassed performance and uptime

18 16 Leica Stainers & Leica Consumables Routine Staining The Perfect Partnership for H&E and Special Stains. High-quality stained slides aid pathologists in making an accurate diagnosis and ensure that patients get the appropriate treatment. Utilizing an automated Leica staining solution with matching Leica stains and reagents simplifies slide preparation and creates a safer work environment.

19 histology solutions 17 Leica ST5020 Multistainer Leica ST5010 Autostainer XL Leica ST4020 Small Linear Stainer Stains & Reagent Solutions: page 121 Routine Staining Solutions Quality high-quality stains and reagents matched to precision automation Flexibility programmable Leica ST5010 Autostainer XL and Leica ST5020 Multistainer automated stainers Productivity fully automated stainer/coverslipper workstations with matching consumables offers a walk-away solution

20 18 Leica Consumables & Leica Coverslippers Coverslipping Enjoy true walk-away staining and coverstaining. Leica workstations link a Leica stainer to the Leica coverslipper so slides are stained and coverslipped without intervention.

21 histology solutions 19 Leica ST5010 Autostainer XL/ CV5030 Workstation Leica ST5020 Multistainer/ CV5030 Workstation Leica CV5030 Coverslipper Slides & Coverglass: page 101 Mounting Media & Adhesives: page 79 Coverslipping Solutions Automated slide transfer simply load, then walk away while slides are stained and coverslipped Manage workloads load on demand, simultaneously run multiple racks with different protocols Increase productivity fully automated, fast and flexible to support Lean workflows

22 20 Leica Storage Systems Storage Archive slides and cassettes with a storage solution from Leica Biosystems. These modular systems take maximum advantage of a laboratory s available storage space and make it easy to organize slides and cassettes for quick retrieval.

23 histology solutions 21 Specimen Transport, Storage & Archiving: page 111 Storage Solutions Modular solutions that grow with a laboratory Efficient take up less valuable laboratory space Organized easily find and retrieve slides and cassettes

24 22

25 histology solutions 23 Leica Consumables Product Range When you re responsible for patient tissue, you need a consumables solution that you trust. Leica Biosystems consumables and laboratory supplies are the quality choice for all aspects of tissue-based pathology. From stains to slides, gloves to glass coverslips this catalog provides a comprehensive list of Leica products. In each section you will find laboratory-proven products for both automated and manual processes. With multiple options for most consumables, this catalog will help you choose products ideally suited to your laboratory. The Leica range covers virtually every histopathology consumable and instrument. Choose Leica Biosystems for a single product, a tailored process solution, or as your partner for a fully integrated histology laboratory. Whenever you need consumables, consult this catalog and find the option that s right for you.

26 24 Contact Region Country Telephone Fax CA Canada US USA EU Austria EU Belgium EU Denmark EU France EU Germany EU Italy EU Netherlands EU Portugal EU Spain EU Sweden EU Switzerland EU United Kingdom (0) AP Australia AP New Zealand AP Japan AP South Korea AP China: Hong Kong AP China: Mainland AP Singapore Visit the Leica Biosystems website for the contact in your area.

27 Section 1 Surgipath Autopsy & Dissection Products designed for speed and accuracy. Ergonomically designed Surgipath autopsy and dissection tools aid accuracy and efficiency. The range covers basic tools such as forceps, knives, chisels, mallets and scalpels as well as specialty items like a spinal cord remover. There is also an advanced product to improve safety such as the Safeshield scalpel with blade protector.

28 Section 1 Surgipath Autopsy & Dissection With multiple autopsy and dissection solutions, Leica Biosystems offers the options you need. The range includes multiple styles and sizes for most products so you can choose the ideal tools for your work practices. It s never one size fits all. It s always the right size for you. Providing the options you need is just one of the ways Leica Biosystems Total Solutions help you deliver a better service at lower costs. All instruments are made from premium grade, hardened stainless steel and feature a protective coating to provide extra durability and protection against rust and corrosion. Each instrument is satin-matt finished to reduce eye-fatiguing glare.

29 01 Autopsy and Dissection 27 Autopsy Autopsy Knife Set This Autopsy Knife Set features a permanent knife holder which accepts four styles of reusable and disposable autopsy Knife Blades. The Blade Holder is easy to clean, able to be sterilized, has a safety finger protector and a grippable inert plastic handle with a stainless steel insert. The Blade Holder is available in left or right handed models. The Knife Blades are manufactured from high quality German stainless steel with scalpel sharpness. Each blade is packaged in a protective plastic cover. The set includes one holder and five of each style of blade. Blades are available individually in packages of five. Section 1 C B A length (150 mm) Sectioning Knife Blade (C) Pack / length (300 mm) Brain Lung Knife Blade (E) Pack / length (80 mm) Skin Knife Blade (A) Pack / length (80 mm) Throat Knife Blade (B) Pack / Blade Holder, right hand (D) Each Blade Holder, left hand Each Knife Set Each E D Feather Autopsy, Trimming and Dissection Range The Feather Autopsy, Trimming and Dissection range is internationally renowned for its sharpness and versatility. The Autopsy Handle is autoclavable, easy to clean and highly chemically resistant. The handle is reusable with a variety of interchangeable disposable stainless steel Autopsy Blades. There are also a number of reusable Trimming Handles that can be used with the disposable Trimming Blades and these are available in right and left handed versions. The F 80 Trimming Handle can be used with Feather Disposable Microtome Blades, converting these ultra sharp high quality blades to trimming tools. The Dissecting Handle, made from a special hard resin, is also autoclavable and can hold two types of longlife ultra sharp disposable Dissecting Blades. The newly developed Feather Safety Trimming System combines the well respected Feather Trimming Blades, with a new blade exchange system, which enables a simple, safe and fast change of blade. The blades are single packed with a blade cover and therefore a direct contact with the Trimming Blade can be avoided. This protects the user from injury and infections. The ergonomically designed plastic handle is heat resistant, autoclavable and easy to clean. The #22 Feather brand scalpel blades are stainless steel, which provide a durable, precision edge. They are packaged individually and are sterile to maximize their applications. Designed to be used with a #4 Stainless Steel contoured handle which accentuates proper feel and dexterity. These blades are also available packaged with disposable, plastic handles. This is an excellent choice where isolation and disposal of the instrument is required to eliminate cross contamination. Scalpel Blade #11 is available for microspecimen and dermopathology applications or where a smaller precision blade is preferred Scalpel Blade, Feather Brand, #22, Sterile Box / Scalpel Blade, Feather Brand, #22, Sterile Box / Scalpel Handle #4, Feather Brand Pack / Scalpel Handle #4, Feather Brand Each Scalpel Handle with #22 Blade, Feather Brand, Box / 20 Disposable, Sterile Scalpel Blade #11 Sterile Box / 100

30 28 Scalpel Blades, Handles Section 1 Disposable Dissection Knives These Disposable Dissection Knives feature a high carbon stainless steel blade cast permanently to an aluminum handle. Individual knives are hollow ground and can be easily sterilized using routine sterilization techniques. Other features include an extra sharp cutting edge and a no slip grip handle. C B A (152 mm) (A) Box / (152 mm) (A) Each (152 mm) (B) Box / (203 mm) (B) Box / (203 mm) (B) Each (203 mm) (B) Box / (305 mm) (C) Box / (305 mm) (C) Each (305 mm) (C) Box / 5 Safeshield Scalpels The Safeshield disposable scalpel features a stainless steel Feather blade protected by a plastic safety shield that can be locked in place or moved. The protective shield slides easily back and forth across the handle and locks into either an open or closed position to expose or cover the blade. The ergonomically designed handle offers ease and user comfort while the sliding protective shield offers users another measure of safety. Each Safeshield Scalpel is individually packaged Safeshield Scalpel Box / 10 Scalpels and Handles Scalpels such as the Round Tip Scalpel Blade are specially designed to reduce the real dangers associated with puncture wounds from sharp pointed blade ends. With the Round Tip Scalpel Blade, it is virtually impossible to inflict a puncture wound. When used together with Cut Resistant or Safetyflex Gloves, staff will be significantly more protected when carrying out cut up or dissection procedures. For added security, the Scalpel Blade Remover enables scalpel blades to be taken off the blade handles safely and securely. The #22 Feather brand scalpel blades are stainless steel, which provide a durable, precision edge. They are packaged individually and are sterile to maximize their applications. These blades are also available packaged with disposable, plastic handles. This is an excellent choice where isolation and disposal of the instrument is required to eliminate cross contamination. C B A Scalpel Blade, Feather Brand, #22, Sterile (C) Box / Scalpel Handle #4, Feather Brand (E) Pack / Scalpel Handle #4, Feather Brand (E) Each E Scalpel Handle #4, Feather Brand (E) Each Scalpel Handle with #22 Blade, Feather Brand, Box / 20 Disposable, Sterile (D) Scalpel Blade #22B, Blunt Tip, Non Sterile Box / Scalpel Blade #60, Non Sterile, Pointed Tip (B) Box / Scalpel Blade #60B, Blunt Tip, Non Sterile (A) Box / Scalpel Blade #11, Sterile Box / DI36412 Scalpel Handle #4L for #22 and #24 Blade (F) Each 38DI36419 Scalpel Handle #4 for #22 and 22B Blades Each D F E Please consult your Leica Biosystems representative for availability in your region

31 01 Autopsy and Dissection 29 Unsterile Carbon Steel Blades Pointed and Blunt Tipped A diverse range of scalpel blades and handles for use in the pathology laboratory and mortuary. #22 and #60 scalpels are available in the traditional pointed tip format or in the #22B and #60B rounded tip or bullnose format for enhanced user safety. These scalpels are made of finest carbon steel and are non sterile. A B Scalpel Blade #22B, Blunt Tip, Non Sterile (E) Box / Scalpel Blade #60, Non Sterile, Pointed Tip (D) Box / Scalpel Blade #60B, Blunt Tip, Non Sterile (C) Box / DI36412 Scalpel Handle #4L for #22 and #24 Blade Each 38DI36418 Scalpel Handle #8 for #60 and 60B Blades (A) Each 38DI36419 Scalpel Handle #4 for #22 and 22B Blades (B) Each Section 1 C D E Dissection Instruments Brain Knife, Skull Breaker, Rachitome Dual sided edged knife for precision brain sectioning. Standard fracturing hammer provides brain access, also available with chisel and hook bottom. Curved rachitome allows for specific skull fracturing. B A 38DI ½ (241 mm) Blade, Brain Knife (A) Each 38DI ½ (140 mm) Skull Breaker (B) Each 38DI ½ (140 mm) Skull Breaker with Chisel End Each 38DI ¾ (222 mm) Rachitome (C) Each C Chisels For the purpose of splitting long and/or dense bone such as the jaw, femur, or sternum autopsy specimens. C B A 38DI ¼ (158 mm) 6 mm Army Pattern Chisel (A) Each 38DI ¼ (158 mm) 12 mm Army Pattern Chisel (B) Each 38DI ¼ (158 mm) 18 mm Army Pattern Chisel (C) Each 38DI ¼ (209 mm) Stille (D) Each D

32 30 Section 1 Knives 86 mm Blade size Cartiledge knife with scalpel style end. 165 mm Blade size Liston knife with tapered end. 203 mm Blade size Liston knife with tapered end. 83 mm Blade autopsy knife with scalpel style end and grooved handle. B A 38DI (86 mm) Blade, Cartilage Knife (A) Each 38DI ½ (165 mm) Blade, Liston Post Mortem Knife (B) Each 38DI (203 mm) Blade, Liston Post Mortem Knife (C) Each 38DI ¼ (83 mm) Blade, Autopsy Knife Each C Liston Bone Cutting Forceps Liston Bone Cutting Forceps are durable bar spring loaded which allows them to self open. For the use of cutting lower density bone and cartiledge. The range includes straight, curved and angular forceps in two sizes. All varieties have a ribbed handle to promote proper grip and cutting leverage. B A 38DI ½ (191 mm) Liston Bone Cutting Forceps, Straight, Ribbed Handles (A) Each D C 38DI DI DI ½ (191 mm) Liston Bone Cutting Forceps, Curved, Ribbed Handles (B) 10 (254 mm) Liston Bone Cutting Forceps, Angular, Ribbed Handles 7½ (191 mm) Liston Bone Cutting Forceps, Angular, Ribbed Handles (C) Each Each Each 38DI (254 mm) Liston Bone Cutting Forceps, Straight, Ribbed Handles (D) Each Mallets 178 mm Mallet with encased lead and 216 mm Mallet for use with bone chisels and other autopsy uses. A 38DI ½ x 1 (216 mm x 25 mm) Mallet (B) Each 38DI ½ x 1 (191 mm x 25 mm) Mallet, Lead Filled (A) Each B Please consult your Leica Biosystems representative for availability in your region

33 01 Autopsy and Dissection 31 Needles, Dissecting Various styles of dissecting needles for multiple applications including grossing and microtomy areas of the lab. A B C D 38DI ¼ (133 mm) Needle, Black Plastic Handle, Spade Each End (A) 38DI ¼ (133 mm) Needle, Black Plastic Handle, Pointed Each End (B) 38DI (127 mm) Needle, One Piece, Metal, Straight (C) Each 38DI (136 mm) Needle, One Piece, Metal, Angled (D) Each 38DI ¼ (133 mm) Needle, Black Plastic Handle, Spade Pack / 6 End 38DI ¼ (133 mm) Needle, Black Plastic Handle, Pointed Pack / 6 End Section 1 Needles, Post Mortem Three sizes of curved post mortem Needles for autopsy applications. A B C 38DI (127 mm) Curved (A) Each 38DI (102 mm) Curved (B) Each 38DI ¾ (70 mm) Curved (C) Each 38DI (127 mm) Curved Pack / 6 38DI (102 mm) Curved Pack / 6 38DI ¾ (70 mm) Curved Pack / 6 Osteotome 13 mm and 25 mm wide x 229 mm long Lambotte osteotomes available for autopsy applications. A B 38DI x ½ (229 mm x 12.5 mm) Lambotte Osteotome Each (A) 38DI x 1 (229 mm x 12.5 mm) Lambotte Osteotome (B) Each Probes Five styles of probes for accurate micro autopsy applications. D B C A 38DI (51 mm) Splinter Probe, Spatula End Each 38DI (102 mm) Splinter Probe, Pointed End (A) Each 38DI ½ (140 mm) Probe, Double End (B) Each 38DI (152 mm) Probe with Eye (C) Each 38DI (152 mm) Director, Grooved with Tongue Tie (D) Each 38DI ½ (140 mm) Probe, Double End Pack / 6 38DI (152 mm) Probe with Eye Pack / 6 38DI (152 mm) Director, Grooved with Tongue Tie Pack / 6

34 32 Section 1 Saws Three styles of manual bone saws. The broad bladed Satterlee saw, the thinner rounded tip Charriere, and the solid handle Langenbech Metacarpal saw. Each saw has serrated teeth for desired cutting. B A 38DI ½ (267 mm) Charriere (B) Each 38DI ½ (292 mm) Satterlee (A) Each 38DI13426 Replacement Blade for Satterlee Saw Each 38DI (229 mm) Langenbech Metacarpal Saw (C) Each C Shears 209 mm Plain rib shears with spring mechanism, Curved. 209 mm Plain rib shears with Eccentric Joint, Curved. 222 mm Gluck rib shears, Curved. A 38DI (209 mm) Plain Rib Shears, Curved (A) Each 38DI (209 mm) Plain Rib Shears, Curved, Eccentric Each Joint (B) 38DI ¾ (222 mm) Gluck Rib Shears, Curved Each B Spatula 216 mm Multi purpose stainless steel blade spatula with bonded wooden handle. 38DI ½ (216 mm) Spatula with Wooden Handle Each Spinal Cord Remover The Spinal Cord Remover facilitates the removal of the intact spinal cord from the cranial cavity without removing the spinal process. 38DI37665 Spinal Cord Remover, V blade = (17.5 mm wide, Each 32 mm long). Shat diameter 2 mm, overall length (excluding handle) 740 mm, (29½ ) Please consult your Leica Biosystems representative for availability in your region

35 01 Autopsy and Dissection 33 Forceps 5½ (140 mm) Ergonomic Available in smooth, serrated or needle tips. These (140 mm) versions are for those who prefer a shorter forcep. The curved styles are well suited for tissue separation in the water bath as well as retrieving small specimens from the inside perimeter of transport jars. Section 1 38DI ½ (140 mm) 1.5 mm Smooth Tips, Straight Each 38DI ½ (140 mm) 1.5 mm Smooth Tips, Curved 30 Each 38DI ½ (140 mm) 1.5 mm Serrated Tips, Curved 30 Each 38DI ½ (140 mm) 1.5 mm Serrated Tips, Straight Each 38DI ½ (140 mm) 1.5 mm Serrated Tips, Needle Tip Each 7 (178 mm) Ergonomic Paddle Handle Available in smooth, serrated, needle tips, and with 1 x 2 teeth. The (185 mm) versions are for those who prefer a longer forcep and greater variety of tip choices. The curved styles are well suited for tissue separation in the water bath as well as retrieving specimens from the inside perimeter of transport jars. 38DI (178 mm) Ergonomic Design Paddle Handle, 3 mm Each Smooth Tips 38DI (178 mm) Ergonomic DesignPaddle Handle, 3 mm Each Serr. Tips 38DI (178 mm) Ergonomic Design Paddle Handle, 3 mm Each 1x2 Teeth 38DI (178 mm) Ergonomic Design Paddle Handle, Each 1.5 mm Smooth T 38DI (178 mm) Ergonomic Design Paddle Each Handle,1.5 mm Serr. Tips 38DI (178 mm) Ergonomic Design Paddle Handle, Each Needle Tip 38DI (178 mm) Ergonomic Design Paddle Handle, Each 1.5 mm Cvd. 30 Serr. Tips 38DI (178 mm) Ergonomic Design Handle, 1.5 mm Cvd. Each 30 Smooth Tips Adson The Adson forceps are avaialble in 4 styles and incorporate paddle style, fine grooved handle. A 38DI ¾ (121 mm) Adson Tissue Forceps, Serr (A) Each 38DI (152 mm) Adson Tissue Forceps, Serr Each 38DI (178 mm) Adson Tissue Forceps, Serr Each 38DI ¾ (121 mm) Adson Tissue Forceps, 1 x 2 Teeth (B) Each B

36 34 Section 1 Coverglass Forceps The Coverglass Forceps are designed for manual coverslipping, incorporating dual enlarged rectangular tips for gripping individual coverslips and eliminating the formation of fingerprints. Available in 2 styles. 38DI ¼ (108 mm) Coverglass Forceps (A) Each 38DI (102 mm) Angled, Smooth Tips (B) Each A B Cushing The Cushing forceps are available in 3 styles and incorporate an elongated depressed handle. These forceps are known for their feel and extra long tip portions. A B 38DI (178 mm) Straight, Smooth Tip (A) Each 38DI (178 mm) Splinter and Potts Smith Type (B) Each 38DI ½ (191 mm) Bayonet, Splinter and Potts Smith Each Type Splinter and Potts Smith The Splinter and Potts Smith forceps are known for their elongated handles and long tip length. The pin to hole construction maintains alignment and creates passivity for the specimen. Available straight only. A B 38DI (152 mm) Splinter, Serrated Tips (A) Each 38DI (152 mm) Splinter, Smooth Tips Each 38DI (178 mm) Splinter and Potts Smith Type 1.5 mm, Each Serrated Tips 38DI ¼ (209 mm) Splinter and Potts Smith Type 1.5 mm, Each Serrated Tips (B) 38DI ½ (241 mm) Splinter and Potts Smith Type 1.5 mm, Each Serrated Tips Thumb Dressing The Thumb Dressing forceps are very popular conventional forceps with a variety of length, tip, and handle styles. C A B 38DI (102 mm) Serrated Tips, Fine Grip Each 38DI (127 mm) Serrated Tips, Fine Grip Each 38DI ½ (140 mm) Serrated Tips, Fine Grip (A) Each 38DI (152 mm) 2 mm Smooth Tips, Broad Grip (B) Each 38DI (178 mm) 2 mm Smooth Tips, Broad Grip Each 38DI (152 mm) Serrated Tips, Fine Grip Each 38DI (152 mm) Serrated Tips, Broad Grip (C) Each 38DI (178 mm) Serrated Tips, Broad Grip Each 38DI (203 mm) Serrated Tips, Broad Grip Each 38DI (305 mm) Serrated Tips, Fine Grip Each Please consult your Leica Biosystems representative for availability in your region

37 01 Autopsy and Dissection 35 Tissue The tissue forceps incorporate a variety of teeth configurements and an array of sizes. B A 38DI (102 mm) 1 x 2 Teeth Each 38DI ½ (140 mm) 1 x 2 Teeth (A) Each 38DI (178 mm) 1 x 2 Teeth Each 38DI (254 mm) 1 x 2 Teeth Each 38DI (127 mm) 3 x 4 Teeth Each 38DI (152 mm) 3 x 4 Teeth (B) Each 38DI (203 mm) 3 x 4 Teeth Each 38DI (254 mm) 3 x 4 Teeth Each Section 1 Hemostats and Clamps Dieffenbach Serrefine These clamps are available in 4 sizes (curved or straight). A B C D 38DI ¾ (45 mm) Straight, Light Model (A) Each 38DI ¾ (45 mm) Curved, Light Model (B) Each 38DI ¼ (57 mm) Straight, Light Model (C) Each 38DI ½ (64 mm) Curved, Light Model (D) Each 38DI ¾ (45 mm) Straight, Light Model Pack / 6 38DI ¾ (45 mm) Straight, Light Model Each 38DI ¾ (45 mm) Curved, Light Model Pack / 6 38DI ¾ (45 mm) Curved, Light Model Each 38DI ¼ (57 mm) Straight, Light Model Pack / 6 38DI ¼ (57 mm) Straight, Light Model Each 38DI ½ (64 mm) Curved, Light Model Pack / 6 38DI ½ (64 mm) Curved, Light Model Each Halsted Mosquito The Halsteds are smaller hemostats (4 )(124 mm) with longer extensions and smaller, intricate tips. Available in straight or curved. A 38DI (124 mm) Straight (A) Each 38DI (124 mm) Curved (B) Each B

38 36 Section 1 Kelly The Kellys are smaller hemostats (5½ ) (140 mm) with longer extensions and smaller, intricate tips. Available in straight or curved. A 38DI ½ (140 mm) Straight (A) Each 38DI ½ (140 mm) Curved (B) Each B Rochester Ochsner The Rochester Ochsners are varied length hemostats (5½ to 9 )(140 to 229 mm) with longer extensions and longer, intricate serrated tips. Available in straight or curved. A B 38DI ½ (140 mm) Straight / 1 x 2 Teeth Each 38DI ½ (140 mm) Curved / 1 x 2 Teeth Each 38DI ¼ (184 mm) Straight / 1 x 2 Teeth (A) Each 38DI ¼ (184 mm) Curved / 1 x 2 Teeth (B) Each 38DI (229 mm) Straight / 1 x 2 Teeth Each 38DI (229 mm) Curved / 1 x 2 Teeth Each Rochester Pean The Rochester Peans are varied length hemostats (140 to 229 mm) with longer extensions and longer, intricate toothed tips. Available in straight or curved. A B 38DI ½ (140 mm) Straight Each 38DI ½ (140 mm) Curved Each 38DI ¼ (184 mm) Straight (A) Each 38DI ¼ (184 mm) Curved (B) Each 38DI (229 mm) Straight Each 38DI (229 mm) Curved Each Please consult your Leica Biosystems representative for availability in your region

39 01 Autopsy and Dissection 37 Scissors Dissecting The Dissecting scissors are available in 20 different varieties of lengths, tip styles, and straight or curved. A C B D 38DI ½ (140 mm) Straight, Sharp / Blunt Tip (A) Each 38DI ½ (165 mm) Straight, Sharp / Blunt Tip Each 38DI (203 mm) Straight, Sharp / Blunt Tip Each 38DI ½ (140 mm) Straight, Sharp / Sharp Tip (B) Each 38DI ½ (165 mm) Straight, Sharp / Sharp Tip Each 38DI (178 mm) Straight, Sharp / Sharp Tip Each 38DI (203 mm) Straight, Sharp / Sharp Tip Each 38DI ½ (140 mm) Straight, Blunt / Blunt Tip (C) Each 38DI ½ (165 mm) Straight, Blunt / Blunt Tip Each 38DI (178 mm) Straight, Sharp / Blunt Tip Each 38DI (203 mm) Straight, Blunt / Blunt Tip Each 38DI ½ (140 mm) Curved, Sharp / Blunt Tip Each 38DI ½ (165 mm) Curved, Sharp / Blunt Tip Each 38DI (203 mm) Curved, Sharp / Blunt Tip Each 38DI ½ (140 mm) Curved, Sharp / Sharp Tip (D) Each 38DI ½ (165 mm) Curved, Sharp / Sharp Tip Each 38DI (203 mm) Curved, Sharp / Sharp Tip Each 38DI ½ (140 mm) Curved, Blunt / Blunt Tip Each 38DI ½ (165 mm) Curved, Blunt / Blunt Tip Each 38DI (203 mm) Curved, Blunt / Blunt Tip Each Section 1 Doyen Doyens are durable Blunt/Blunt abdominal scissors. The dual blunt tips maximizes cutting efficiency and decreases the probability of puncturing tissue. A B 38DI (178 mm) Abdominal, Straight, Blunt / Blunt Tip Each (A) 38DI (178 mm) Abdominal, Curved, Blunt / Blunt Tip Each (B) Enterotomy The Enterotomy scissors are for use in the cutting of bowel tissue. Available in Hook or Probe Blade designs. A 38DI ¼ (209 mm) Enterotomy Bowel Scissors, Hook Each Blade (A) 38DI ¼ (209 mm) Enterotomy Bowel Scissors (B) Each B

40 38 Section 1 Gradle Scissors These ultra small scissors are designed for microdissection and dermatological uses. 38DI ¾ (95 mm) Gradle, Slightly Curved, Sharp Tip Each Iris The Iris scissors are designed with slightly elongated reach and smaller very intricate blade tips. All scissors are 114 mm long and are available with straight, curved, or 3 styles of angled tips. A C B 38DI ½ (114 mm) Straight, Sharp / Sharp Tip (A) Each 38DI ½ (114 mm) Curved, Sharp / Sharp Tip (B) Each 38DI ½ (114 mm) Angled Over Edge (C) Each 38DI ½ (114 mm) Angled, Sharp / Blunt Tip, No Probe Each 38DI ½ (114 mm) Angled Over Edge, Probe Point (D) Each D Mayo The Mayo scissors are durable, medium reach, with tapered tips. Available in 3 lengths (staright or curved). B A 38DI ½ (140 mm) Straight (A) Each 38DI ½ (140 mm) Curved (B) Each 38DI ¾ (171 mm) Straight Each 38DI ¾ (171 mm) Curved Each 38DI (229 mm) Straight Each 38DI (229 mm) Curved Each Metzenbaum The Metzenbaum Scissors are designed with an extra long reach and smaller, intricate blade length. This design promotes the abilty to achieve precission cutting in difficult to reach areas. B A 38DI ½ (114 mm) Curved Each 38DI ¾ (146 mm) Straight (A) Each 38DI ¾ (146 mm) Curved (Lahey) (B) Each 38DI (178 mm) Straight Each 38DI (178 mm) Curved (Lahey) Each 38DI (229 mm) Straight Each 38DI (229 mm) Curved (Lahey) Each Please consult your Leica Biosystems representative for availability in your region

41 01 Autopsy and Dissection 39 Utility The Utility Scissors are high quality all purpose scissors ideal for use in the laboratory. 38DI ½ (191 mm) Serrated Shears, Plastic Handle Rings Each Section 1 Dissection Boards Dissection Board The Dissection Board is constructed of a heavy duty, hard acrylic plastic material that makes it ideal for supporting soft tissues that are subjected to the cutting and dissection process. The shiny white or blue surface provides an excellent background contrast for visualizing specimens. They can easily be positioned on the board without slippage or moving around on the surface. The board is supported by five rubber feet that are positioned on each of the four corners and in the center to raise the board off the table or grossing station base. 38DI x 13 (584 x 330 mm), Surgipath Dissection Each Board Instrument Cases Instrument Cases Instrument Cases are vinyl, zippered and velour lined with inside protective closures. Allows organization and/or privitizes dissection instruments. Available in two sizes. Instruments not included. 38DI ¾ x 15 (324 x 381 mm) Instrument Case holds Each up to 39 instruments 38DI x 14 (254 x 356 mm) Instrument Case holds up Each to 33 instruments

42 40 Section 1 Tissue Marking and Margin Dyes Tissue Marking and Margin Dyes Tissue Marking and Margin Dyes are used to microscopically identify specific areas of tissue specimens that have diagnostic importance, for identification and orientation of excised surgical specimens, and for the method of marking margins of skin tissue when utilizing Mohs techniques. The formulation of the Surgipath Tissue Marking and Margin Dyes utilize dye pigments in a specific viscosity controlled solution, to penetrate and stain designated areas of tissue specimens Tissue Marking & Margin 7 Color Kit. Each Includes 1 each dye color, Acrylic Base, and 100 count Bag of Dual End Applicator Sticks Tissue Marking & Margin Dye Blue 2 oz. (59 ml) Each Bottle Tissue Marking & Margin Dye Green 2 oz. (59 ml) Each Bottle Tissue Marking & Margin Dye Black 2 oz. (59 ml) Each Bottle Tissue Marking & Margin Dye Yellow 2 oz. (59 ml) Each Bottle Tissue Marking & Margin Dye Red 2 oz. (59 ml) Each Bottle Tissue Marking & Margin Dye Orange 2 oz. (59 ml) Each Bottle Tissue Marking & Margin Dye Violet 2 oz. (59 ml) Each Bottle Dual End Applicator Sticks 100 Count Bag Each Please consult your Leica Biosystems representative for availability in your region

43 Section 1 01 Autopsy and Dissection 41

44 42 Section 1 Dissection Instruments Reference Tips Tips Sharp / Sharp S / S Smooth Sharp / Blunt S / B Serrated Blunt / Blunt B / B Diamond Curved Grips 1 x 2 Teeth 3 x 4 Teeth Fine Broad Davis (Russian) Please consult your Leica Biosystems representative for availability in your region

45 Section 2 Surgipath Sectioning Blades Consistent sharpness and durability, for quality sections. To help you cut the best possible sections, Leica Biosystems has a broad range of blades and knives for microtomes and cryostats. This range consists of both high and low profile disposable microtome blades to provide precision cutting for all tissue types including difficult tissue types such as uterus. Whether for dense or soft tissue, frozen or routine sectioning, biopsies or large tissue samples, Leica Biosystems has a range of blades to meet your sectioning needs.

46 Section 2 Surgipath Sectioning Blades High-quality sectioning starts with high-quality blades. Not just instruments, not just consumables, but cohesive systems working in harmony. Create complete sectioning solutions with Leica microtomes and cryostats using Leica blades. It s a team of champions. It s a champion team. Delivering systems where blade and instrument are ideally matched is just one of the ways Leica Biosystems Total Solutions help you deliver exceptional quality. Providing perceptibly improved results.

47 02 Sectioning Blades 45 Blades Premium High Profile Disposable Blade Surgipath DB80 HS Cut the very thin sections needed for diagnostic clarity. The DB80 HS provides a new level of quality with an advanced high profile shape, a premium finish and edge to edge, blade to blade consistency. Length: 80 mm, Width: 14 mm, Angle: High Profile DB80 HS Blades Case / High Profile DB80 HS Blades Box / 50 Section 2 Premium Low Profile Disposable Blade Surgipath DB80 LS Cut the very thin sections needed for diagnostic clarity. The DB80 LS provides a new level of quality with an advanced low profile shape, a premium finish and edge to edge, blade to blade consistency. Length: 80 mm, Width: 8 mm, Angle: Low Profile DB80 LS Blades Case / Low Profile DB80 LS Blades Box / 50 Premium Low Profile Disposable Blade for Hard Samples Surgipath DB80 LX Now you can cut high quality thin sections from dense specimens. With select materials, sophisticated coating and an advanced profile, this blade quickly and efficiently slices your hard samples. Length: 80 mm, Width: 8 mm, Angle: Low Profile DB80 LX Blades Case / Low Profile DB80 LX Blades Box / 50

48 46 High Profile Disposable Blades 818 High Profile disposable microtome blades for routine sectioning. Comprised of high quality stainless steel with dimensions of 80x14x0.35mm (LxHxD). Featuring a 35 degree angle. Qty 50 blades per dispenser, qty 10 dispensers per case High Profile Blades 818 Case / High Profile Blades 818 Box / 50 Section 2 High Profile Disposable Microtome Blades The High Profile Disposable Microtome Blade is a unique blade that rivals the traditional reusable microtome blade for routine sectioning. It offers heavier gauge steel than most disposable brands, eliminating any vibrating issues when cutting through extremely hard or fibrous specimens. No wiping of the blade is necessary, with all blades providing consistently sharp, clean edges. The blades are supplied in an ejector dispenser pack, featuring a storage compartment for the safe discard of spent blades. High Profile Coated Blades come in 10 pack cases containing 500 blades or single boxes of 50 blades. Thick Super Blades are available in boxes containing 20 blades. Thin Economy Blades are available in boxes containing 50 blades High Profile, Coated Case / High Profile, Coated Box / High Profile, Thick Box / High Profile, Thin Box / 50 Low Profile Disposable Blades 819 Low Profile disposable microtome blades for routine histology sectioning. Comprised of high quality stainless steel with dimensions of 80x14x0.25mm (LxHxD). Featuring a 35 degree angle. Qty 50 blades per dispenser, qty 10 dispensers per case Low Profile Blades 819 Case / Low Profile Blades 819 Box / 50 Please consult your Leica Biosystems representative for availability in your region

49 02 Sectioning Blades 47 Low Profile Disposable Microtome Blades / Triple Facet Microtome Blade Low Profile Disposable Microtome Blades / Triple Facet Microtome Blades are manufactured from high carbon stainless steel. Close attention is paid to providing consistently sharp, finely honed blades necessary to meet the high quality sectioning standards required in today s histology laboratories. The blades fit a standard low profile blade holder and are supplied in an ejector dispenser pack, featuring a storage compartment for the safe discard of spent blades. The blades come in 10 pack cases containing 500 blades or single boxes of 50 blades Low Profile, Triple Facet Box / Low Profile, Triple Facet Case / Low Profile, Coated Case / Low Profile, Coated Box / Low Profile, Thin Box / 50 Section 2 Feather Blades Feather Disposable Microtome Blades The Feather Autopsy, Trimming and Dissection range is internationally renowned for its sharpness and versatility. Made from stainless steel, each blade is heat treated and finely ground in three stages to produce a precise cutting edge. The blades are then specially coated to minimize friction and maximize blade longevity. A variety of blades are available, each suited to a particular application or tissue type: Feather S35 A low profile blade for all routine sectioning. Feather R35 Enables easier ribboning. Ideal for hard fibrous tissue. Feather N35 Suitable for hard tissue and for thin sectioning. Feather A35 For routine sectioning of soft and hard tissue. Also suited for thinner sections. Feather S22 For cutting soft tissue and obtaining extremely thin sections. Ideal for skin, lymph node and renal biopsies. Feather S35L A longer 120 mm version of the Feather S35 to facilitate the cutting of larger blocks normally on a sledge or sliding microtome. Feather S35LL A longer 180 mm version of the Feather S35 to facilitate the cutting of very large blocks. A sliding microtome is required to use this blade. Feather C35 A disposable carbon steel blade ideally suited for sectioning in a cryostat. Able to shear very thin frozen sections. Feather S35 High Profile Twice the depth of the Feather S35 (requiring a specific High Profile blade holder). Suitable for all routine sectioning. With the exception of the C35 Blade, it is recommended to trim in all Feather microtome blades to improve blade longevity. During trimming in of the blade, care must be taken not to damage the surface coating, as this can cause scoring. Available in packs of Feather S35 Pack / 50 CN only Feather R35 Pack / 50 CN only Feather N35 Pack / 50 CN only Feather A35 Pack / 50 CN only

50 48 Ancillary Frostbite New ozone safe Frostbite does not contain CFC s but still retains its ability to rapidly cool paraffin blocks and tissue. Two quick bursts are all that is needed to ensure deeper penetration into both paraffin blocks and fresh tissue specimens. The trigger nozzle and needle tube help to localize spray. This reduces excess spray coverage and Section 2 eliminates waste. Frostbite is nonflammable oz (300 ml) can Case / oz (300 ml) can Each EE 250 ml can Case / 12 Heavy Duty Disposable Blades Disposable Blade H45L is a heavy duty disposable blade suited to be used with disposable blade holder 157 AR. The blade is 157 x 14 x 0.8 mm (L x H x D) and features a 45 degree cutting angle. One box contains ten blades Disposable Blades H45L Box / 10 Knife Facet Wipers Grit free foam wipers effectively clean both facets of knife edge without dulling or damaging the blade Knife Facet Wipers (10/pkg) Package Please consult your Leica Biosystems representative for availability in your region

51 02 Sectioning Blades 49 Surgipath 3800 Water Bath The Surgipath 3800 Water Bath has a non-glaring white LED illumination to aid the user in viewing ribbons, the glass dish is positioned over a black background that provides excellent contrast against the opague, translucent ribbon. The large horizontal design promotes the support for positioning and stretching of long ribbons for normal use of serial sectioning, step sectioning or teaching slides. Multiple paraffin ribbons can be laid down consecutively to allow for discriminating selection of sections. The available left and right orientation heaters for flattening of sections onto slide before drying. Temperature can be accurately controlled within +/- 1. Maximum temperature achievable is 60 C Surgipath 3800 Water Bath (120V) with Each 9 X 13 with removable glass dish insert Section 2 Leica HI1210 The Leica HI1210 is a water bath with a surface that provides high thermal conductivity rates and outstanding scratch resistance due to its special plastic coating. Temperatures can be selected between ambient and 75 C. To increase safety and reliability the Leica HI1210 features an overheating protection system along with a standby mode. The broad, oversized rim of the water bath allows convenient storage for microscope slides, and the rounded inner corners of the instrument allow it to be cleaned easily and efficiently Leica HI1210 ( V) Each Leica HI1220 The Leica HI1220 flattening table has a large jet black aluminum work surface to provide high thermal conductivity rates and outstanding resistance to mechanical manipulations. Temperatures ranging from ambient to 75 C can be selected, with work surface temperatures above 44 C being indicated by a flashing LED, to guard against overheating of specimens. The programmed, as well as the current, temperatures are displayed on the instrument and the set values are memorized via a built-in battery backup system Leica HI1220 ( V) Each

52 50 Trimease The SURGIPATH 9000 TRIMEASE is a compact heating station for melting and removing excess paraffin from embedded cassettes. Simply move block along heated anodized aluminum ribbed surface to remove excess paraffin. Saves time and eliminates use of dangerous sharps to scrape off paraffin. Temperature adjustable from ambient to 75 C through membrane control panel SURGIPATH 9000 TRIMEASE (120V) Each Section 2 Please consult your Leica Biosystems representative for availability in your region

53 Section 3 Surgipath Cassettes & Base Molds Designed to increase efficiency and improve your workflow. Leica creates solutions where everything works together. Delivering cassettes that increase efficiency at every step is just one of the ways Leica Biosystems Total Solutions help you create optimized workflows. Surgipath cassettes don t just hold tissue and form blocks, they offer a complete solution for secure specimen identification, optimized tissue processing, high-productivity embedding and efficient sectioning. The range includes many options so you can select the best solution for your laboratory. Choose from standard and innovations that drive increased productivity. Unique products include ActivFlo cassettes for maximum fluid exchange and ParaFree base molds that virtually eliminate block scraping.

54 52 Section 3 Surgipath Cassettes & Base Molds Delivering total solutions means always looking at the entire process never an individual product in isolation. Secure your tissue, aid in enhancing processing and eliminate block trimming. Surgipath cassettes, biopsy pads/wraps and base molds may help improve your laboratory s workflow. Delivering total solutions means always looking at the entire process never an individual product in isolation. Providing perceptibly improved results. Please consult your Leica Biosystems representative for availability in your region

55 03 cassettes and Base Molds 53 Processing Cassettes IP Routine Cassette I IP Routine Cassette I features a 45 degree writing surface and is designed for use with standard metal lids. Both the cassette base and the metal lid have the familiar round hole design for enhanced fluid exchange and drainage. Available in 11 colors in quantities of 2,000. Cassettes are taped for easy loading into a Leica IP C Cassette Printer White, Taped Case / 2, Pink, Taped Case / 2, Green, Taped Case / 2, Yellow, Taped Case / 2, Blue, Taped Case / 2, Peach, Taped Case / 2, Tan, Taped Case / 2, Gray, Taped Case / 2, Lilac, Taped Case / 2, Orange, Taped Case / 2, Aqua, Taped Case / 2,000 Section 3 Processing Cassettes Processing Cassettes are precision molded using solvent resistant plastic. Features include a three sided textured writing surface, easy flow through vents and 50 degree writing surface. Processing Cassettes are compatible with most metal lids and base molds. Available in 14 colors in quantities of 1,000 and 2, Lavender Bulk / 2, White Bulk / 2, Blue Bulk / 2, Aqua Bulk / 2, Yellow Bulk / 2, Orange Bulk / 2, Green Bulk / 2, Pink Bulk / 2, Tan Bulk / 2, Peach Bulk / 2, Gray Bulk / 2, Kelly Green Bulk / 2, Melon (Red) Bulk / 2, Purple Bulk / 2, White Case / 1, Blue Case / 1, Aqua Case / 1, Yellow Case / 1, Orange Case / 1, Green Case / 1, Pink Case / 1, Tan Case / 1, Peach Case / 1, Gray Case / 1, Kelly Green Case / 1, Melon (Red) Case / 1, Purple Case / 1, Lavender Case / 1,000 39LC Metal Lids for use with processing cassettes Pack / 25

56 54 IP Routine VIII, for Metal Lids IP Routine VIII cassettes are processing cassettes for use with a metal lid. The cassettes feature a 45 degree writing surface and secure latch closure. The cassettes have been designed for optimal workflow in the Leica IP C Cassette Printer and offer <1% printing error rate. Available in loose and taped packaging for easy printer loading. Choose from 11 colors in cases of 1,000. Includes 25 metal lids per case. Section 3 39LC White Case / 1,000 39LC Blue Case / 1,000 39LC Aqua Case / 1,000 39LC Green Case / 1,000 39LC Lilac Case / 1,000 39LC Pink Case / 1,000 39LC Orange Case / 1,000 39LC Gold Case / 1,000 39LC Yellow Case / 1,000 39LC Tan Case / 1,000 39LC Gray Case / 1,000 39LC L White, Taped Case / 1,000 39LC L Blue, Taped Case / 1,000 39LC L Aqua, Taped Case / 1,000 39LC L Green, Taped Case / 1,000 39LC L Lilac, Taped Case / 1,000 39LC L Pink, Taped Case / 1,000 39LC L Orange, Taped Case / 1,000 39LC L Gold, Taped Case / 1,000 39LC L Yellow, Taped Case / 1,000 39LC L Tan, Taped Case / 1,000 39LC L Gray, Taped Case / 1,000 39LC Metal Lids for Routine VIII Case / 25 Please consult your Leica Biosystems representative for availability in your region

57 03 cassettes and Base Molds 55 Routine Cassettes IP Routine II Cassette, with Closed Lid IP C Routine II Cassette features a one piece, integrated, closed lid that opens from the back, toward the writing surface. The lids can be opened and closed many times and will relock securely. The cassettes feature a 45 degree writing surface and are taped for easy loading into Leica IP C Cassette Printer. Available in 11 colors in quantities of 2, White, Taped Case / 2, Pink, Taped Case / 2, Green, Taped Case / 2, Yellow, Taped Case / 2, Blue, Taped Case / 2, Peach, Taped Case / 2, Tan, Taped Case / 2, Gray, Taped Case / 2, Lilac, Taped Case / 2, Orange, Taped Case / 2, Aqua, Taped Case / 2,000 Section 3 IP Routine III Cassette IP Routine III Cassette is a one piece processing cassettes with a 35 degree writing surface. The cassettes are taped for easy loading in the IP C Cassette Printer. Available in 11 colors in quantities of 1, White, Taped Case / 1, Pink, Taped Case / 1, Green, Taped Case / 1, Yellow, Taped Case / 1, Blue, Taped Case / 1, Peach, Taped Case / 1, Tan, Taped Case / 1, Gray, Taped Case / 1, Lilac, Taped Case / 1, Orange, Taped Case / 1, Aqua, Taped Case / 1,000

58 56 Multi Cassettes Multi Cassettes are two piece tissue cassettes, used for tissue processing and embedding. They feature a unique hinge and are precision molded from a solvent and acid resistant plastic. The cassettes have a three sided textured writing surface, parallel flow vents and thick walls for stability. The opening tab is enlarged and rounded, making it easy to open. Raised nibs on all four corners of each lid help to keep cassettes apart during processing, ensuring thorough fluid exchange. This cassette has a detachable lid and a universal base unit. Available in 15 colors in quantities of 2,000 (base only) or 1,000 (assembled). Section Lavender, Unassembled Bases & Lids Bulk / 2, White, Unassembled Bases & Lids Bulk / 2, Blue, Unassembled Bases & Lids Bulk / 2, Aqua, Unassembled Bases & Lids Bulk / 2, Yellow, Unassembled Bases & Lids Bulk / 2, Orange, Unassembled Bases & Lids Bulk / 2, Green, Unassembled Bases & Lids Bulk / 2, Pink, Unassembled Bases & Lids Bulk / 2, Tan, Unassembled Bases & Lids Bulk / 2, Peach, Unassembled Bases & Lids Bulk / 2, Gray, Unassembled Bases & Lids Bulk / 2, Kelly Green, Unassembled Bases & Lids Bulk / 2, Melon (Red), Unassembled Bases & Lids Bulk / 2, Purple, Unassembled Bases & Lids Bulk / 2, Lavender, Base Only Bulk / 2, White, Base Only Bulk / 2, Blue, Base Only Bulk / 2, Aqua, Base Only Bulk / 2, Yellow, Base Only Bulk / 2, Orange, Base Only Bulk / 2, Green, Base Only Bulk / 2, Pink, Base Only Bulk / 2, Tan, Base Only Bulk / 2, Peach, Base Only Bulk / 2, Gray, Base Only Bulk / 2, Kelly Green, Base Only Bulk / 2, Melon (Red), Base Only Bulk / 2, Purple, Base Only Bulk / 2, Kelly Green (assembled base and lids) Case / 1, Purple (assembled base and lids) Case / 1, Lavender (assembled base and lids) Case / 1, White (assembled base and lids) Case / 1, Blue (assembled base and lids) Case / 1, Yellow (assembled base and lids) Case / 1, Green (assembled base and lids) Case / 1, Pink (assembled base and lids) Case / 1, Tan (assembled base and lids) Case / 1, Peach (assembled base and lids) Case / 1, Gray (assembled base and lids) Case / 1, Red (Melon) (assembled base and lids) Case / 1, Aqua (assembled base and lids) Case / 1, Orange (assembled base and lids) Case / 1,000 Please consult your Leica Biosystems representative for availability in your region

59 03 cassettes and Base Molds 57 One Piece Tissue Cassettes One Piece Tissue Cassettes are specially designed with a break off hinge. A rear locking mechanism, coupled with an enlarged front latch type lock, combine to ensure tissue security. The opening tab is enlarged and rounded, making it easy to open. Raised nibs on all four corners of each lid help to keep cassettes apart during processing, ensuring thorough fluid exchange. Cassettes offers a 50 degree writing surface. Available in 14 colors in quantities of 1, White Case / 1, Blue Case / 1, Yellow Case / 1, Green Case / 1, Pink Case / 1, Tan Case / 1, Peach Case / 1, Gray Case / 1, Lavender Case / 1, Kelly Green Case / 1, Purple Case / 1, Aqua Case / 1, Orange Case / 1,000 Section 3 Pre Load I Multi Cassette Pre Load I Cassettes are pre packaged cassettes that are compatible with automatic cassette printers. The pre packaged cassettes feature a robust, seamless tube, providing a smooth internal surface through which the cassettes can slide without obstruction. Pre load Multi Cassettes come in cases of 1,232 cassettes, (77 cassettes per tube (16 tubes per case) White, Multi Cassette Case / 16 tubes Blue, Multi Cassette Case / 16 tubes Yellow, Multi Cassette Case / 16 tubes Green, Multi Cassette Case / 16 tubes Pink, Multi Cassette Case / 16 tubes Tan, Multi Cassette Case / 16 tubes Peach, Multi Cassette Case / 16 tubes Gray, Multi Cassette Case / 16 tubes Lavender, Multi Cassette Case / 16 tubes Melon (Red), Multi Cassette Case / 16 tubes Purple, Multi Cassette Case / 16 tubes Kelly Green, Multi Cassette Case / 16 tubes Aqua, Multi Cassette Case / 16 tubes Orange, Multi Cassette Case / 16 tubes

60 58 ActivFlo Routine I Cassette ActivFlo Routine I cassettes are processing cassettes featuring a patented lateral vent design for maximum fluid exchange. The increase in fluid exchange results in less incidence of unfixed or under processed tissues and faster fixation/processing of tissue specimens. These one piece cassettes have frangible lids for easy removal. The cassettes have a 45 degree writing surface and are designed for optimal workflow in the Leica IP C Cassette Printer. They offer <1% printing error rate. Available in loose and taped packaging for easy printer loading. Choose from assorted colors in cases of 1,000. Section 3 39LC White Case / 1,000 39LC Blue Case / 1,000 39LC Aqua Case / 1,000 39LC Green Case / 1,000 39LC Lilac Case / 1,000 39LC Pink Case / 1,000 39LC Orange Case / 1,000 39LC Gold Case / 1,000 39LC Yellow Case / 1,000 39LC Tan Case / 1,000 39LC Gray Case / 1,000 39LC L White, Taped Case / 1,000 39LC L Blue, Taped Case / 1,000 39LC L Aqua, Taped Case / 1,000 39LC L Green, Taped Case / 1,000 39LC L Lilac, Taped Case / 1,000 39LC L Pink, Taped Case / 1,000 39LC L Orange, Taped Case / 1,000 39LC L Gold, Taped Case / 1,000 39LC L Yellow, Taped Case / 1,000 39LC L Tan, Taped Case / 1,000 39LC L Gray, Taped Case / 1,000 IP Routine VI Cassette IP Routine VI cassettes are one piece cassettes with frangible hinges for easy lid removal, a 45 degree writing surface and a secure latch closure. The cassettes have been designed for optimal workflow in the Leica IP C Cassette Printer and offer <1% printing error rate. The cassettes are available both in loose and taped packaging for easy printer loading. Choose from assorted colors in cases of 1, LC White Case / 1,000 39LC Blue Case / 1,000 39LC Aqua Case / 1,000 39LC Green Case / 1,000 39LC Lilac Case / 1,000 39LC Pink Case / 1,000 39LC Orange Case / 1,000 39LC Gold Case / 1,000 39LC Yellow Case / 1,000 39LC Tan Case / 1,000 39LC Gray Case / 1,000 39LC L White, Taped Case / 1,000 39LC L Blue, Taped Case / 1,000 39LC L Aqua, Taped Case / 1,000 39LC L Green, Taped Case / 1,000 39LC L Lilac, Taped Case / 1,000 39LC L Pink, Taped Case / 1,000 39LC L Orange, Taped Case / 1,000 39LC L Gold, Taped Case / 1,000 39LC L Yellow, Taped Case / 1,000 39LC L Tan, Taped Case / 1,000 39LC L Gray, Taped Case / 1,000 Please consult your Leica Biosystems representative for availability in your region

61 03 cassettes and Base Molds 59 IP Routine VII Cassette IP Routine VII cassettes are two piece cassettes with a hinge lid, 45 degree writing surface and secure latch closure. The cassettes have been designed for optimal workflow in the Leica IP C Cassette Printer and offer <1% printing error rate. Available in loose and taped packaging for easy printer loading. Choose from assorted colors in cases of 1,000. The taped cassettes include lids. The loose cassettes, lids must be ordered separately. 39LC White Case / 1,000 39LC Blue Case / 1,000 39LC Aqua Case / 1,000 39LC Green Case / 1,000 39LC Lilac Case / 1,000 39LC Pink Case / 1,000 39LC Orange Case / 1,000 39LC Gold Case / 1,000 39LC Yellow Case / 1,000 39LC Tan Case / 1,000 39LC Gray Case / 1,000 39LC L White, Taped Case / 1,000 39LC L Blue, Taped Case / 1,000 39LC L Aqua, Taped Case / 1,000 39LC L Green, Taped Case / 1,000 39LC L Lilac, Taped Case / 1,000 39LC L Pink, Taped Case / 1,000 39LC L Orange, Taped Case / 1,000 39LC L Gold, Taped Case / 1,000 39LC L Yellow, Taped Case / 1,000 39LC L Tan, Taped Case / 1,000 39LC L Gray, Taped Case / 1,000 39LC White, Covers Case / 1,000 39LC Blue, Covers Case / 1,000 39LC Aqua, Covers Case / 1,000 39LC Green, Covers Case / 1,000 39LC Lilac, Covers Case / 1,000 39LC Pink, Covers Case / 1,000 39LC Orange, Covers Case / 1,000 39LC Gold, Covers Case / 1,000 39LC Yellow, Covers Case / 1,000 39LC Tan, Covers Case / 1,000 39LC Gray, Covers Case / 1,000 Section 3

62 60 Biopsy Cassettes Biopsy Cassettes Biopsy Cassettes are designed to allow processing of the smallest specimens without the need to use foam inserts or lens paper. The rigidly constructed cassettes are made of solvent and acid resistant plastic featuring a textured writing surface on three sides, a 50 degree writing angle and an attached hinged lid. Biopsy cassettes also feature 1 x 1 mm square holes to permit complete fluid exchange and thorough paraffin infiltration and a stay shut closure design. Available in assorted colors and quantities. Section Aqua Case / Orange Case / Lavender Case / White Case / Blue Case / Yellow Case / Green Case / Pink Case / Tan Case / Peach Case / Gray Case / Melon (Red) Case / Kelly Green Case / Purple Case / White Bulk / 2, Lavender Bulk / 2, Blue Bulk / 2, Yellow Bulk / 2, Green Bulk / 2, Pink Bulk / 2, Tan Bulk / 2, Peach Bulk / 2, Gray Bulk / 2, Melon (Red) Bulk / 2, Kelly Green Bulk / 2, Purple Bulk / 2, Aqua Bulk / 2, Orange Bulk / 2, White (two pieces unassembled) Bulk / 2, Lavender (two pieces unassembled) Bulk / 2, Blue (two pieces unassembled) Bulk / 2, Yellow (two pieces unassembled) Bulk / 2, Green (two pieces unassembled) Bulk / 2, Pink (two pieces unassembled) Bulk / 2, Tan (two pieces unassembled) Bulk / 2, Peach (two pieces unassembled) Bulk / 2, Gray (two pieces unassembled) Bulk / 2, Melon (Red) (two pieces unassembled) Bulk / 2, Kelly Green (two pieces unassembled) Bulk / 2, Purple (two pieces unassembled) Bulk / 2, Aqua (two pieces unassembled) Bulk / 2, Orange (two pieces unassembled) Bulk / 2,000 Please consult your Leica Biosystems representative for availability in your region

63 03 cassettes and Base Molds 61 IP Biopsy Cassette, with Closed Lid IP Biopsy Cassettes have six numbered compartments that measure 7 x 12 mm each. These cassettes feature 0.36 mm square holes in the both the covers and bases of the cassettes. The lids are attached and arrive closed. The cassettes feature a 45 degree writing surface and are taped for easy loading into a Leica IP C Cassette Printer. Available in 11 colors in quantities of 2, White, Taped Case / 2, Pink, Taped Case / 2, Green, Taped Case / 2, Yellow, Taped Case / 2, Blue, Taped Case / 2, Peach, Taped Case / 2, Tan, Taped Case / 2, Gray, Taped Case / 2, Lilac, Taped Case / 2, Orange, Taped Case / 2, Aqua, Taped Case / 2,000 Section 3 IP Biopsy I Cassette, with Closed Lid IP Biopsy Cassette I has an attached lids that opens from the back, toward the writing surface. The lids arrive closed and relock securely after opening and closing. The pore size in the base and lid is 1.0 mm. The cassettes feature a 45 degree writing surface and are taped for easy loading into a Leica IP C Cassette Printer. Available in 6 colors in quantities of 2, White, Taped Case / 2, Pink, Taped Case / 2, Green, Taped Case / 2, Yellow, Taped Case / 2, Blue, Taped Case / 2, Peach, Taped Case / 2,000 IP Biopsy II Cassette IP Biopsy II Cassette is a one piece biopsy cassettes with 1 mm pores and a 35 degree writing surface. The cassettes are offered taped for easy loading into a Leica IP C Cassette Printer. Available in 7 colors in quantities of 1, White, Taped Case / 1, Pink, Taped Case / 1, Green, Taped Case / 1, Yellow, Taped Case / 1, Blue, Taped Case / 1, Peach, Taped Case / 1, Gray, Taped Case / 1,000

64 62 IP Biopsy III Cassette, with Closed Lid IP Biopsy III Cassette features a 0.38 mm pore size allowing for excellent fluid exchange without having to use biopsy pads or paper. Large anterior and posterior slots in both the cassettes and covers ensure that the cassettes will not float. The large, square compartment measures 27 mm. The covers do not protrude over the cassettes, which allows easier stacking in a tissue processor basket. Available in 7 colors. Cassettes feature a 45 degree writing surface and are taped for easy loading into a Leica IP C Cassette Printer. Section White, Taped Case / 2, Pink, Taped Case / 2, Green, Taped Case / 2, Yellow, Taped Case / 2, Blue, Taped Case / 2, Peach, Taped Case / 2, Gray, Taped Case / 2,000 IP Biopsy IV Cassette, with Closed Lid IP Biopsy IV Cassettes have a compartment measuring 25 mm by 30 mm. Biopsy pads are not necessary since the holes in the cassette and lid have a diameter of only 0.26 mm, making them similar in function to mesh cassettes. The holes allow efficient fluid exchange and drainage. Available in 10 colors. Cassettes feature a 45 degree writing surface and are taped for easy loading into a Leica IP C Cassette Printer White, Taped Case / 2, Pink, Taped Case / 2, Green, Taped Case / 2, Yellow, Taped Case / 2, Blue, Taped Case / 2, Peach, Taped Case / 2, Tan, Taped Case / 2, Gray, Taped Case / 2, Lilac, Taped Case / 2, Aqua, Taped Case / 2,000 Microbiopsy Cassettes Microbiopsy Cassettes are specially designed to accommodate extremely small specimens and tissue biopsies. These cassettes feature a 0.38 mm pore size and have a separate compartment with larger holes for rapid fluid exchange. The large anterior and posterior slots in both the cassettes and covers also ensure that the cassettes will not float. The large, square compartment measures 27 mm. The covers do not protrude over the cassettes, which allows easier stacking in a tissue processor basket. The cassettes can easily be opened and closed with one hand. Available in 7 colors in cases of 1, White Case / 1, Blue Case / 1, Yellow Case / 1, Green Case / 1, Pink Case / 1, Aqua Case / 1, Orange Case / 1,000 Please consult your Leica Biosystems representative for availability in your region

65 03 cassettes and Base Molds 63 One Piece Microbiopsy Cassettes One Piece Microbiopsy Cassettes are designed to process even the smallest tissue biopsies including bone marrow biopsies. Extra tiny flow through holes (0.3 mm) prevent the loss of any specimen, yet allow unhindered fluid exchange. The cassette features a 50 degree writing surface and are available in 14 colors in cases of 1, White Case / 1, Lavender Case / 1, Blue Case / 1, Yellow Case / 1, Green Case / 1, Pink Case / 1, Tan Case / 1, Peach Case / 1, Gray Case / 1, Melon (Red) Case / 1, Purple Case / 1, Kelly Green Case / 1, Aqua Case / 1, Orange Case / 1,000 Section 3 Pre Load I Biopsy Cassettes Pre Load I Cassettes Biopsy Cassettes are pre packaged tubed cassettes that are compatible with automatic cassette printers. The pre packaged cassettes feature a robust, seamless tube, providing a smooth internal surface through which the cassettes can slide without obstruction. Preload Biopsy cassettes come in cases of 1,200 cassettes, (75 cassettes per tube) (16 per case) White, Biopsy Cassette Case / 16 tubes Blue, Biopsy Cassette Case / 16 tubes Yellow, Biopsy Cassette Case / 16 tubes Green, Biopsy Cassette Case / 16 tubes Pink, Biopsy Cassette Case / 16 tubes Tan, Biopsy Cassette Case / 16 tubes Peach, Biopsy Cassette Case / 16 tubes Gray, Biopsy Cassette Case / 16 tubes Lavender, Biopsy Cassette Case / 16 tubes Melon (Red), Biopsy Cassette Case / 16 tubes Purple, Biopsy Cassette Case / 16 tubes Kelly Green, Biopsy Cassette Case / 16 tubes Aqua, Biopsy Cassette Case / 16 tubes Orange, Biopsy Cassette Case / 16 tubes

66 64 IP ActivFlo Biopsy I Cassette IP ActivFlo Biopsy I cassettes are a one piece cassette featuring a patented Fluidic Flow pore design for maximum reagent exchange. With a 0.67 mm pore size, the cassettes include an innovative V shape pore design that pulls fluid in and forces air out. The cassettes feature sloped walls, creating a basket for small tissue management. These one piece cassettes with frangible lids have been designed for use with the Leica IP C Cassette Printer, with a 45 degree writing surface and <1% printing error rate. Available in loose and taped packaging for easy printer loading. Choose from assorted colors in cases of 500 loose or 1,000 taped. Section 3 39LC White Case / LC Blue Case / LC Aqua Case / LC Green Case / LC Lilac Case / LC Pink Case / LC Orange Case / LC Gold Case / LC Yellow Case / LC Tan Case / LC Gray Case / LC L White, Taped Case / 1,000 39LC L Blue, Taped Case / 1,000 39LC L Aqua, Taped Case / 1,000 39LC L Green, Taped Case / 1,000 39LC L Lilac, Taped Case / 1,000 39LC L Pink, Taped Case / 1,000 39LC L Orange, Taped Case / 1,000 39LC L Gold, Taped Case / 1,000 39LC L Yellow, Taped Case / 1,000 39LC L Tan, Taped Case / 1,000 39LC L Gray, Taped Case / 1,000 Please consult your Leica Biosystems representative for availability in your region

67 03 cassettes and Base Molds 65 IP ActivFlo Biopsy II Cassette IP ActivFlo Biopsy II cassettes are a two piece cassette featuring a patented Fluidic Flow pore design for maximum reagent exchange. With a 0.67 mm pore size, the cassettes include an innovative V shape pore design that pulls fluid in and forces air out. The cassettes also feature sloped walls, creating a basket for small tissue management. These two piece cassettes with hinged lids have been designed for use with the Leica IP C Cassette Printer, with a 45 degree writing surface and <1% printing error rate. Available in loose and taped packaging for easy printer loading. Choose from assorted colors. 39LC White Case / LC Blue Case / LC Aqua Case / LC Green Case / LC Lilac Case / LC Pink Case / LC Orange Case / LC Gold Case / LC Yellow Case / LC Tan Case / LC Gray Case / LC L White, Taped Case / 1,000 39LC L Blue, Taped Case / 1,000 39LC L Aqua, Taped Case / 1,000 39LC L Green, Taped Case / 1,000 39LC L Lilac, Taped Case / 1,000 39LC L Pink, Taped Case / 1,000 39LC L Orange, Taped Case / 1,000 39LC L Gold, Taped Case / 1,000 39LC L Yellow, Taped Case / 1,000 39LC L Tan, Taped Case / 1,000 39LC L Gray, Taped Case / 1,000 Section 3 IP ActivFlo Biopsy III Cassette IP ActivFlo Biopsy III cassettes are a two piece cassette featuring a patented Fluidic Flow pore design for maximum reagent exchange. With a 0.26 mm pore size, the cassettes can secure the smallest specimens, eliminating the need for biopsy bags and sponges. The cassettes also feature sloped walls, creating a basket for small tissue management. These two piece cassettes with hinged lids have been designed for the Leica IP C Cassette Printer, with a 45 degree writing surface and <1% printing error rate. Available in loose and taped packaging for easy printer loading. Choose from assorted colors in cases of 500 loose or 1,000 taped. 39LC White Case / LC Blue Case / LC Aqua Case / LC Green Case / LC Lilac Case / LC Pink Case / LC Orange Case / LC Gold Case / LC Yellow Case / LC Tan Case / LC Gray Case / LC L White, Taped Case / 1,000 39LC L Blue, Taped Case / 1,000 39LC L Aqua, Taped Case / 1,000 39LC L Green, Taped Case / 1,000 39LC L Lilac, Taped Case / 1,000 39LC L Pink, Taped Case / 1,000 39LC L Orange, Taped Case / 1,000 39LC L Gold, Taped Case / 1,000 39LC L Yellow, Taped Case / 1,000 39LC L Tan, Taped Case / 1,000 39LC L Gray, Taped Case / 1,000

68 66 IP Biopsy VI Cassette IP Biopsy VI cassettes are two piece biopsy cassettes with 0.67 mm pores, 45 degree writing surface and a secure latch closure. The cassettes have been designed for use with the Leica IP C Cassette Printer and offer <1% printing error rate. Available in loose and taped packaging for easy printer loading. Choose from assorted colors, in quantities of 500 loose or 1,000 taped. Section 3 39LC White Case / LC Blue Case / LC Aqua Case / LC Green Case / LC Lilac Case / LC Pink Case / LC Orange Case / LC Gold Case / LC Yellow Case / LC Tan Case / LC Gray Case / LC L White, Taped Case / 1,000 39LC L Blue, Taped Case / 1,000 39LC L Aqua, Taped Case / 1,000 39LC L Green, Taped Case / 1,000 39LC L Lilac, Taped Case / 1,000 39LC L Pink, Taped Case / 1,000 39LC L Orange, Taped Case / 1,000 39LC L Gold, Taped Case / 1,000 39LC L Yellow, Taped Case / 1,000 39LC L Tan, Taped Case / 1,000 39LC L Gray, Taped Case / 1,000 Specialty Cassettes ActivFlo Mini Biopsy Cassette ActivFlo Mini Cassettes are one third the size of standard cassettes featuring a 0.67mm pore, ideal for needle biopsies and small tissues. The cassettes feature sloped walls, creating a basket for small tissue management. The smaller size allows for double the number of blocks to be stored, decreasing the space required for specimen storage. An excellent solution for microwave and rapid tissue processors. Choose from assorted colors in quantities of LC White Case / LC Blue Case / LC Aqua Case / LC Green Case / LC Lilac Case / LC Pink Case / LC Orange Case / LC Gold Case / LC Yellow Case / LC Tan Case / LC Gray Case / 500 Please consult your Leica Biosystems representative for availability in your region

69 03 cassettes and Base Molds 67 Mega Cassettes, Double Depth Double the depth of conventional cassettes, Mega Cassettes allow for easier embedding and processing of larger specimens. Complete with a plastic hinged lid these rigid, durable cassettes have excellent writing surfaces and are available in six colors in quantities of 1,000. The cassette dimensions are 40 x 28 x 13 mm. 38VSP59040 White Case / 1,000 38VSP59041 Orange Case / 1,000 38VSP59042 Blue Case / 1,000 38VSP59044 Yellow Case / 1,000 38VSP59045 Green Case / 1,000 38VSP59046 Red Case / 1,000 Super Cassettes Super Cassettes allow the processing* and/or embedding of large sections of brain, eyes, intact joints, some whole animal organs, whole prostates, complete multiple tissue cases and any other larger specimens. Ideal for veterinary and research pharmaceutical laboratories. *Processing schedules must be adjusted accordingly. Dimensions: 3 x 2 x ¾ (75 x 52 x 17 mm). Available in 7 colors in case of 100. Section 3 38VSP59060 White Case / VSP59061 Orange Case / VSP59062 Blue Case / VSP59064 Yellow Case / VSP59065 Green Case / VSP59066 Red Case / VSP59067 Gray Case / 100

70 68 Base Molds Metal Base Molds Metal Base Molds enable tissue to be positioned and embedded in wax when using routine or biopsy cassettes. These reusable base molds are made from stainless steel the internal rounded corners allow for easy removal of the formed wax block. They can be used on all standard size cassettes. Available in packs of twelve. Section x 7 x 6 mm Pack x 15 x 6 mm Pack x 24 x 6 mm Pack x 24 x 6 mm Pack x 24 x 6 mm Pack 12 ParaFree TM Stainless Steel Base Mold ParaFree TM Stainless Steel Base Molds offer higher walls then other base molds in the market, eliminating excess paraffin build up around the block. The unique design produces paraffin blocks that require 80% less block scraping before sectioning. The precise corners of the mold help to facilitate immediate ribboning. 39LC x 7 x 4 mm Pack 12 39LC x 15 x 4 mm Pack 12 39LC x 25 x 4 mm Pack 12 39LC x 25 x 4 mm Pack 12 39LC x 25 x 4 mm Pack 12 Pop Ups Aluminum Base Molds Pop Ups Aluminim Base Molds feature an innovative design for improving and speeding up tissue embedding. This all aluminum base mold quickly cools paraffin blocks faster than conventional molds. After repeated use, they can be recycled. Each base mold is manufactured to create a flat surface which allows histotechs to quickly face into the tissue. The paraffin blocks set up so quickly that you can hear the blocks pop out of the mold when they re ready. Available in a box of x 7 x 4.5 mm Box / x 15 x 4.5 mm Box / x 24 x 5.0 mm Box / x 24 x 4.5 mm Box / x 24 x 4.5 mm Box / 50 Please consult your Leica Biosystems representative for availability in your region

71 03 cassettes and Base Molds 69 ParaFree Disposable Base Mold ParaFree Disposable Base Molds include a patented block alignment system for even and consistent parallel block facing. The Base Molds offer higher walls then others in the market, eliminating excess paraffin build up around the block. The unique design produces paraffin blocks that require no scraping before sectioning. The corners of the molds are 90 degrees, facilitating immediate ribboning. 39LC x 10 x 5.4 mm Case / LC x 15 x 5.4 mm Case / LC x 24 x 5.4 mm Case / LC x 24 x 5.4 mm Case / LC x 24 x 5.4 mm Case / 500 Disposable Base Molds Disposable Base Molds have been designed to be compatible with most cassettes on the market. The orientation of the specimen is made easier due to the transparency Section 3 of the mold, while its rounded corners allow for easy block removal and paraffin ribbon continuity. Built up side walls reduce the risk of paraffin seepage during embedding. Available in boxes of 400 or cases of 1, Clear 8 x 10 x 5 mm Box / Clear 8 x 10 x 5 mm Case / 1, Clear 15 x 15 x 5 mm Box / Clear 15 x 15 x 5 mm Case / 1, Clear 24 x 24 x 5 mm Box / Clear 24 x 24 x 5 mm Case / 1, Clear 30 x 24 x 5 mm Box / Clear 30 x 24 x 5 mm Case / 1, Clear 37 x 24 x 5 mm Box / Clear 37 x 24 x 5 mm Case / 1,600 Mini Metal Base Mold Designed to work with the ActivFlo Mini cassette, Mini Metal Base Molds require 33% less paraffin for embedding and provide a superior frame for the embedded tissue when exposed to the microtome blade for sectioning. Use of the mini molds increases the number of sections, ribbons and levels per slide. 39LC x 6 x 3.25 mm Pack / 12 39LC x 12 x 3.25 mm Pack / 12 39LC x 18 x 3.25 mm Pack / 12 Super Metal Base Molds For specimens processed in super cassettes, the Super Metal Base Molds fit perfectly for embedding large specimens. 38VSP x 54 x 15 mm Box / 2 38VSP x 54 x 15 mm Box / 10

72 70 Biopsy Pads and Wraps Bio Wraps Bio Wraps are sections of tissue paper cut to a convenient, ready to use 2 ½ x 4 (63 x 100 mm) size. They are colored blue to help locate small biopsy specimens following paraffin infiltration. They will not bleed into specimens. Bio Wraps are available in convenient dispenser packs x 3 (50 x 75 mm) Box / x 3½ (127 x 89 mm) Box / ½ x 4 (63 x 100 mm) Box / 500 Section 3 Biopsy Pads Biopsy Pads are made from open celled foam, which allows fluids to transfer safely and thoroughly around tissue while holding the specimen securely. To prevent floating and avoid artifacts, Biopsy Pads should be presaturated in fixative. The thin design helps eliminate excess pressure from being applied to unfixed specimens, reducing the risk of tissue sticking to the pads or fibers coming apart during embedding. Available in white or blue foam, circular or rectangular. The thinner pads also allow for less fluid carry over during processing Blue, 1 x 1¼ (25 x 30 mm) Bulk / 10, Blue, 1 x 1¼ (25 x 30 mm) Bag / White, 1 x 1¼ (25 x 30 mm) Bag / Blue, 1 (35 mm) Circle Bag / Blue, 1 (25 mm) Circle Bag / Blue, ¾ (19 mm) Circle Bag / 500 Mesh Biopsy Bags Manufactured from solvent resistant nylon, these Mesh Biopsy Bags are ideal for use in processing small biopsies. They provide excellent fluid exchange and maximum tissue safety. The fixative and specimen can be poured into the bag which then filters the fixative and leaves the biopsies inside. The bag is then closed, placed inside a cassette and processed as normal. After processing, the bag can be extracted and opened, allowing the specimen to be recovered and embedded in paraffin wax ¼ x 1¾ (60 x 45 mm) Pack / 1, ¾ x 1¼ (45 x 30 mm) Pack / 1, ¾ x 1¼ (45 x 30 mm) Bag / ¼ x 1¾ (60 x 45 mm) Bag / 500 Please consult your Leica Biosystems representative for availability in your region

73 Section 3 03 cassettes and Base Molds 71 Marking Pens Marking Pens These laboratory Marking Pens are extremely versatile and are compatible with various writing surfaces found in the laboratory. They have an extra fine point made of rigid nylon for precise marking on glass slides as well as tissue cassettes. The quick drying ink is highly resistant to aqueous based stains, alcohols, xylene and xylene substitutes. A tight fitting cap helps prevent drying of the tip. The pen barrel is ergonomically designed for ease of use Marking Pens Box / 12

74 72 Section 3 Please consult your Leica Biosystems representative for availability in your region

75 Section 4 Surgipath Cytology Maximize patient comfort, collection efficiency and specimen quality. The Surgipath cytology range includes specialized collection devices that let you choose the ideal tool for each task, funnels that work with the market-leading centrifuge and cytology fixatives in pre-filled jars or easy-to-use sprayers. There are also accessories to help organize cytology specimens and PAP kits that can be tailored to individual requirements.

76 74 Section 4 Surgipath Cytology Innovation that improves laboratory practice and helps deliver better patient care. Innovative Surgipath cytology accessories have been developed through close customer collaboration. The results are improved efficiency for clinicians, better cell collection for laboratories, and reduced discomfort for patients. Improving lives through innovation. Finding new ways to advance the diagnostic process is just one of the ways Leica Biosystems Total Solutions help you improve patient care. Please consult your Leica Biosystems representative for availability in your region

77 04 cytology 75 Collection Devices C E Brush The C E Brush is specifically designed to gently collect an adequate amount of endocervical material for a more accurate pap smear diagnosis. The bristle head is barrel shaped (as opposed to cone shaped). The longer bristles at the tip cause less discomfort and bleeding to the patients, while allowing for a greater collection surface when harvesting cells from the squamal columnar junction. This brush is designed to be inserted into the endocervical canal and rotated slowly C E Brush Box / C E Brush Box / C E Brush Box / C E Brush Box / 500 Cervical Scrapers Cervical Scrapers come in three different designs. The Ayres Tip Scraper is designed to collect cytology specimens from the cervix and is also adaptable to collect specimens from the tongue, throat or vulva. The Elongated Tip Scraper allows deeper penetration into the endocervical area. The Duo End Scraper enables the clinician to use either the Ayres Tip or modified Elongated Tip, providing cell samples from both cervix and endocervix in one step. Section Plastic Duo End Cervical Scrapers Bag / 500 Cervix Brush The Cervix Brush, from Rovers Medical Devices BV, provides a clear and accurate sample for the early detection of cervical cancer. It is made of polythylene and has a total length of 7 ¾ (200 mm). The top portion uses a soft, flexible brush to obtain cell samples, while the shape allows the top edges to follow the contours of the cervix. The longer middle bristles reach deep into the endocervical canal while the shorter bristles touch both the ectocervical area (external os) and the transformation zone (T zone). Cells from the entire cervical area may be collected to produce good, representative samples. The detachable head makes it ideal use for Liquid Based Cytology systems Cervex Brush Box / 25

78 76 Snap Off C E Brush The Snap Off C E Brush has been produced to work with today s liquid base cytology automated systems and comes in a 7.5 length. The snap off 1.75 portion is removable from the rest of the stem. This portion can then easily be dropped into a preparation jar for transport Snap Off C E Brush Bag / Snap Off C E Brush Bag / Snap Off C E Brush Bag / 500 Fixatives Section 4 Cytology Fixative Cytology Fixative combines a convenient fine mist spray dispenser with a polyethylene glycol formulation to enable the rapid, high quality fixation of cytology cell spreads. Cytology Fixative covers cells with a tough, soluble film that protects cell morphology for microscopic examination. It is water and alcohol soluble, environmentally friendly and extremely economical. Cytology Fixative is also available in 50 ml dropper bottles if preferred Cytology Fixative, 1 fl. oz (30 ml) (Discontinued) Case / Cytology Fixative, 4 fl. oz (188 ml) Case / 12 Spray Fix Cytology Fixative Aerosol Container Spray Fix Cytology Fixative Aerosol Container is a high quality cytology fixative that combines the desirable features of ethyl alcohol with those of polyethylene glycol. The freezing effect that many aerosols have on cells is eliminated because no fluorocarbon propellants are used Spray Fix, Aerosol Can, 3 oz Can / 12 Please consult your Leica Biosystems representative for availability in your region

79 04 cytology 77 Accessories Cytocuvettes Cytocuvettes are designed for cytology for use in cytology centrifuges. They are simple and easy to use, eliminate the use of metal clips and reduce decontamination. Cytocuvettes are ideal when researching clinical non gyn specimens. 39MC 0389 Cytofunnel Disposable Sample 1 Chamber Each 39MC 0619 Cytofunnel Disposable Sample 1 Chamber with Each Separate Filter Card 39MC 0682 Cyto Cuvette Duo Disposable Sample 2 Chambers Each 39MC 0684 Cyto Cuvette Duo Disposable Sample 2 Chambers Each with Separate Filter Card 39MC 0671 Cyto Cuvette Kit 1 with Slide Ground Edge White Each 39MC 0673 Cyto Cuvette Kit 1 with 1 Raised White Circle Each 39MC 0771 Cyto Cuvette Kit 2 with Slide Ground Edge White Each 39MC 0773 Cyto Cuvette Kit 2 with 2 Raised White Circles Each Cyto Jar The Cyto Jar is for the convenient collection, fixation and preservation of all cytologic specimens. The 120 ml clear, resistant container is prefilled with 45 ml of preservative containing polyethylene glycol. It can be used for rinsing aspiration needles or bronchial brushes and for the direct collection of sputum specimens. Section ml Jar Case / Empty Bulk Pack Case / 400 Cytology Funnel The Cytology Funnel is a specially designed unit that facilitates the transfer of spun down non gyn specimens on to microscope slides. The unit incorporates two separate chambers with a single cap design. For the price of a single chamber unit, cytotechnologists can have the option of preparing one or two cytopreps at a time on a single slide. The attached white filter card wicks away excess supernatant, eliminating cell loss Surgipath Single Funnel, White Filter Card Pack / Surgipath Single Funnel, White Filter Card Case / Surgipath Single Funnel, Brown Filter Card Pack / Surgipath Double Funnel, White Filter Card Pack / Surgipath Double Funnel, White Filter Card Case / Surgipath Cytology funnel Clips for Shandon Rotor Pack / 6

80 78 Section 4 Please consult your Leica Biosystems representative for availability in your region

81 Surgipath Mounting Media & Adhesives Section 5 Choose the mounting or embedding media that s ideal for your laboratory. The Surgipath range includes media for both manual and automated coverslipping, paraffin and frozen sections, xylene, or xylene-free clearing. There are also resins, adhesives and frozen sectioning compounds. So no matter how you like to work, there s a Surgipath media or adhesive that will work for you.

82 Section 5 Surgipath Mounting Media & Adhesives Take advantage of Leica Biosystems advanced knowledge to find the right solution for you. Your Leica Biosystems representative has detailed product expertise that will help you choose the ideal mounting media and adhesives for your applications. It s never just about a sale. It s always about helping make the right decision. Using our knowledge to create long-term value for your laboratory is just one of the ways Leica Biosystems Total Solutions help you become a leader in tissue-based pathology.

83 05 Mounting Media 81 Mounting Media Acrytol Acrytol is a rapid drying, toluene based mounting medium which enables slides to be screened immediately. It has a low viscosity, allowing the medium to flow easily. It also prevents air bubbles from becoming trapped. Acrytol contains an antioxidant to inhibit stain fading and prevent the formation of annual rings. A thin coating of Acrytol is all that is needed to adhere a coverglass to a microscope slide. It is soluble in xylene, toluene and most xylene substitutes. Refractive Index (Wet), (Dry) Acrytol, 2 oz (59 ml) Case / Acrytol, 4 oz (118 ml) Dripper Bottle Case / Acrytol, 4 oz (118 ml) Dripper Bottle Each Acrytol, Pint (473 ml) Each Acrytol, Pint (473 ml) Case / 4 Clearium Clearium is a mounting medium which enables slide preparations to be simultaneously cleared and coverslipped in one easy step. This unique product eliminates the need to use hazardous xylene or xylene substitutes as a clearing agent in histology and cytology laboratories. When using Clearium, simply do away with the final step of clearing and coverslip directly from absolute isopropyl alcohol. Refractive Index (Wet), (Dry) Clearium, Pint (473 ml) Each Clearium, Pint (473 ml) Case / Clearium, 4 fl. oz (118 ml) Dripper Bottle Case / 12 Section 5 CureMount CureMount is a UV curable mounting medium of low viscosity for use with all dehydrated sections. CureMountTM is a polymer that cures to a refractive index of It closely matches the refractive index of dehydrated tissue. The cover slip can be optimally positioned and cured under UV fluorescent illumination. The coverslipped slide is dry in less than 30 seconds. Not for use with automated coverslippers CureMount, 60 ml Each

84 82 Leica CV Mount The CV Mount is suitable for all common robotic coverslippers, as well as for manual coverslipping procedures. This coverslipping reagent does not contain any dangerous organic solvents Leica CV Mount, 250 ml Case / 4 Leica CV Ultra The CV Ultra is suitable for all common robotic coverslippers, as well as for manual coverslipping procedures. This coverslipping reagent does not contain any dangerous organic solvents. This product is a good choice for certain sensitive IHC staining. Minimizes fading. Available in 100 ml or 250mL sizes Leica CV Ultra, 100 ml Case / Leica CV Ultra, 250 ml Each Section 5 Micromount Micromount is a rapid drying, xylene based mounting medium. Its low viscosity facilitates coverslipping and prevents air bubble formation. An antioxidant is added to inhibit stain fading and prevent the formation of annual rings. Micromount sets up quickly, allowing slide preparations to be handled immediately after mounting. Micromount is soluble in xylene, toluene, and most xylene substitutes. Refractive Index (Wet), (Dry) Micromount, Pint (473 ml) Case / Micromount, Pint (473 ml) Each Micromount, 4 fl. oz (118 ml) Dripper Bottle Case / 12 Please consult your Leica Biosystems representative for availability in your region

85 05 Mounting Media 83 MM 24 MM 24 is a low viscosity, ultra fast drying, toluene based mounting medium that is compatible with both aliphatic (eg Sub X) and aromatic (eg xylene) clearing agents. It is specially formulated to provide optimum results with automatic glass coverslippers, yet is also effective when manually preparing slides. Set up time before permanent filing can be as quickly as 24 hours when used with aromatic agents and 48 to 72 hours when used with aliphatics. Refractive Index (Wet), (Dry) MM 24, 473 ml Each MM 24, 473 ml Case / MM 24, 4 fl. oz (118 ml) Dripper Bottles Case / 12 Sub X Mounting Medium Sub X Mounting Medium is a quick drying, permanent, toluene based mountant formulated to be compatible with a Sub X Clearing Agent and all xylene substitutes on the market. It is toluene based and may also be used to cover slip preparations cleared with xylene or toluene. Its low viscosity provides an easy flow, bubble free medium suitable for manual as well as automated coverslipping. Sub X contains an antioxidant to inhibit fading of stains. Refractive Index (Wet), (Dry) Sub X, Pint (473 ml) Each Sub X, Pint (473 ml) Case / Sub X, 2 oz (59 ml) Case / Sub X, 4 fl. oz (118 ml) Dripper Bottle Case / 12 Section 5 Frozen Section Media Cryo Gel Cryo Gel is a highly viscous, water soluble embedding medium for frozen sections. It eliminates the messiness of runny media and is excellent for retaining sample orientation during freezing. The pump bottle quickly dispenses the gel in any position, even when almost empty Cryo Gel, 4.3 oz (128 ml) Case / 12

86 84 FSC 22 FSC 22 is a water soluble embedding compound used in frozen sectioning. The compound bonds and encapsulates tissue specimens to the object holder for cryosectioning. It provides excellent sectioning consistency with minimal curling of sections at a working temperature of 20 C. FSC 22 is available in clear or in light blue for better visualization of small specimens FSC 22, Clear, 4 fl. oz (118 ml) Case / S FSC 22, Clear, 4 fl. oz (118 ml) Each FSC 22, Blue, 4 fl. oz (118 ml) Case / S FSC 22, Blue, 4 fl. oz (118 ml) Each OCT Compound OCT Compound is highly viscous and water soluble, making it an excellent choice for supporting tissue during cryotomy. Available in a 125 ml dripper bottle OCT Compound, (125 ml) Each Section 5 Please consult your Leica Biosystems representative for availability in your region

87 05 Mounting Media 85 Water Bath Adhesive Silane Solution Silane Solution is suited to all immunohistochemical procedures and provides excellent section adhesion when used on glass microscope slides Silane Solution, Pint (473 ml) Each Sta On Tissue Section Adhesive Sta On is a liquid adhesive that is easy to use, convenient and reliable. Ten milliliters are added to each liter of pre warmed water in a tissue flotation bath. Sta On has been lab tested with H&E staining, special stains and immunoperoxidase procedures. Diluted Sta On can be used to coat slides for frozen sections and smear preparations Sta On, Pint (473 ml) Each Sta On, Gallon (3.8 L) Each Section 5

88 86 Section 5 Please consult your Leica Biosystems representative for availability in your region

89 06 Paraffin 87 Surgipath Paraffin Section 6 Formulations developed with consistent quality and dependability in mind. With a variety of set-point temperatures, additives and characteristics, there is a Surgipath paraffin to meet your processing, embedding and sectioning requirements. Whichever product you choose, you can be sure you are getting a premium product that will produce the quality you expect.

90 88 Section 6 Surgipath Paraffin Quality is fundamental; it s never an option. Surgipath paraffin products all feature high-quality formulations. Quality means everything to us, because we know quality means everything to you. Built-in quality is just one of the ways Leica Biosystems Total Solutions help you consistently meet or exceed your quality standards. Please consult your Leica Biosystems representative for availability in your region

91 06 Paraffin 89 Paraffin Paraplast Paraplast is recommended for general tissue embedding. It is composed of a refined mixture of highly purified paraffin containing plastic polymers of regulated molecular weights. This supports improved tissue infiltration and superior quality sections with minimal compression. Paraplast gives brittle, difficult to section tissue an innate elasticity, promoting wrinkle free sections. It has a melting point of 56 C. Paraplast Plus is suggested for large tissue or tissue that may normally present infiltration issues. Paraplast Plus contains a small percentage of dimethyl sulfoxide (DMSO), allowing accelerated tissue penetration. It has a melting point of 56 C. Paraplast Xtra is recommended for lower temperature infiltration which aids in the prevention of tissue distortion. It is composed of a unique blend of low molecular weight polymers and highly purified paraffins for compression resistance and ribbon continuity. Low viscosity permits complete infiltration of dense tissue. It has a melting point of 52 C. Paraplast Highmelt embedding media is made from a combination of highly purified wax and plastic polymers of regulated molecular weights. Paraplast HM is most commonly used when sectioning with a sliding microtome and in exceedingly warmer climates where sectioning with conventional paraffins is difficult on rotary microtomes. It has a melting point of 60 C Paraplast, 1 kg Bags (A) Case / 8 Bags Paraplast, Bulk, 5 kg Bags Bulk / 4 Bags Paraplast Plus, 1 kg Bags (B) Case / 8 Bags Paraplast Xtra, 1 kg Bags (C) Case / 8 Bags Paraplast Highmelt (D) Case/ 4 Bags (A) (B) (C) (D) Formula R Formula R is a next generation paraffin that enables thin sectioning with minimal compression and all around ease of use. Formula R is a semitransparent compound which can be used both as an infiltration and embedding medium. It has a low melting point (56 57 ºC, and higher water bath temperature ºC) and is available in a wide mouth plastic jug which makes disposing of the used paraffin simple and easy. Available in 2 lb bags or 4.5 lb jugs Formula R, 4.5 lb Plastic Jugs Case / 4 Jugs Formula R, 2 lb Bags Case / 10 Bags Section 6

92 90 Tissue Infiltration Medium Tissue Infiltration Medium is a special formulation of purified paraffin and plastic polymers for infiltration specifically. Thorough impregnation of all types of tissue specimens can be achieved with either open or closed automatic processor systems. This medium can be used in conjunction with EM 400. It is stable and will not break down or separate at low or high temperatures. Available in 2 lb bags. Melting Point: ºC. Water Bath Temperatures: ºC Tissue Infiltration Medium, 2 lb Bags Case / 10 Bags EM 400 Embedding Medium EM 400 Embedding Medium is a blend of purified paraffin with synthetic polymers that enables sectioning with minimal compression. The medium can facilitate routine sectioning at 1 2 microns on a rotary microtome. Its low melting point (56 57 ºC, water bath temperature ºC) reduces potential artifactual distortion in tissues heated above 60º during paraffin impregnation. EM 400 will remain stable even at elevated temperatures. It is available in a case of 10 x 2 lb (0.91 kg) lightweight bags to facilitate handling EM 400 Embedding Medium, 2 lb Bags Case / 10 Bags Section 6 Blue Ribbon Blue Ribbon is a universal paraffin containing synthetic polymers that can be used both as an infiltration and embedding medium. The paraffin enables the impregnation of tissue to occur rapidly and completely. Its low melting point (56 57 ºC, water bath temperature ºC) means it is highly recommended for use with immunoperoxidase procedures. The wax however will remain stable even at elevated temperatures. It is available in a case of 10 x 2 lbs (0.91 kg) lightweight bags to facilitate handling Blue Ribbon, 2 lb Bags Case / 10 Bags Please consult your Leica Biosystems representative for availability in your region

93 Section 6 06 Paraffin 91 Leica PELORIS Parablocks Peloris Parablocks are pre formed blocks of paraffin that are provided in plastic molds. The pre formed blocks fit easily into the paraffin chamber of the PELORIS Tissue Processor and allows complete walk away versus having to top off to reach desired fill level when using pellet or flake paraffin. 39V1001 PELORIS Parablocks 1 liter Blocks Case / 5 Blocks Leica ASP300 S & Leica ASP6025 Parablocks ASP Parablocks are pre formed blocks of paraffin that are provided in plastic molds. The preformed blocks fit easily into the paraffin chamber of the ASP300 S Tissue Processor and the Leica ASP6025. Once the chamber is filled with the solid paraffin blocks which allows complete walk away versus having to top off to reach desired fill level when using pellet or flake paraffin. 39V2001 ASP Parablocks Case / 4 Blocks

94 92 Section 6 Please consult your Leica Biosystems representative for availability in your region

95 Surgipath Safety and Hygiene The Surgipath range extends beyond instruments and consumables to products that protect the most Section 7 valuable asset in any laboratory the staff. Because all laboratories must comply with safety standards and all staff deserve optimum protection, Leica offers many ways to maintain a healthy and safe laboratory environment.

96 Surgipath Safety and Hygiene Section 7 Staff are a vital part of any laboratory so the Surgipath range includes products vital for staff welfare. Delivering products that help improve all aspects of tissue-based pathology is just one of the ways Leica Biosystems Total Solutions help you meet modern laboratory standards.

97 07 Safety and Hygiene 95 Chemical Control Airchek Badges Airchek Badges provide an innovative, simple and effective system to monitor vapour levels. Standard badges are available for formaldehyde, glutaraldehyde, xylene, toleune, and isopropanol. The Airchek badges provide continuous sampling for personal monitoring and can give the measurements required under Government regulations. The badges are simply clipped on to the technician s clothing and a record is kept of name, location and time. One badge will provide continuous sampling over 8 hours and a second badge can be used to supply information to analyse a 15-minute period during peak exposure. Both badges are then sent to Leica Biosystems to be forwarded to an independent accredited laboratory for analysis Formaldehyde Box / Glutaraldehyde Box / Xylene Box / Toluene Box / Isopropanol Box / 6 D-Formalizer Pad Dispenser For use with the D-Formalizer Pad Rolls, this handy dispenser makes cutting lengths effortless. The metal dispenser will hold a Roll of D-Formalizer Pad securely and uses a spring-pressured guide to keep the Roll in place. The Pad can then be easily unrolled to the required length and cut with a knife. The Dispenser can be mounted horizontally or vertically on a bench top or under a bench cabinet D-Formalizer Roll, 14 x 51 (356 mm x 15.5 m) Each DS Roll Dispenser Each D-Formalizer Pads D-Formalizer Pads reduce formaldehyde exposure by absorbing and neutralising any excess formalin. The durable blue surface of the pads provides an excellent contrast to Section 7 even small pieces of tissue. The Pads are also useful for soaking up leakage and de-odourising vapours in other applications. They can be used to line shelves which hold specimen containers that may seep formaldehyde around the lid, or to line transport boxes where leaks may occur. D-Formalizer Pads are available in various sizes and also in a convenient roll so that lengths can be cut as required. For best results, the D-Formalizer Pad Roll should be used with the D-Formalizer Pad Dispenser. Pads come in packs of 25 and sizes include 203 x 254 mm, 280 x 356 mm, 406 x 508 mm. D-Formalizer role is 356 x 15.5 m D-Formalizer Pads, 8 x 10 (203 x 254 mm) Pack / D-Formalizer Pads, 11 x 14 (280 x 356 mm) Pack / D-Formalizer Pads, 16 x 20 (406 x 508 mm) Pack / 25

98 96 D-Formalizer Powder D-Formalizer is a safe chemical treatment for neutralizing spent formalin. It leaves a clear solution, free of solids and aldehyde odor, that can be disposed of without clogging the drains. Simply add one packet of D-Formalizer to a gallon of used formalin (or 4% glutaraldehyde) and agitate gently. After 15 minutes, the product can be safely poured down the drain in compliance with local ordinances. The resulting solution will have a ph between 6 and 9 and will be free of polymer by-product. An aldehyde kit is also available to test for residual aldehyde and includes 100 tests per box. D-Formalizer is available per package or in a case of 10 packages D-Formalizer, 1.5 lb (680 g) Case / 10 Packages D-Formalizer Package Each Aldehyde Test Kit Box / 100 Tests F.C.G. Unlike general absorption products, which soak up spillage, F.C.G. deactivates chemicals and converts formaldehyde into a solid slurry, inert mass of urea-formaldehyde which can be disposed of as a non-hazardous waste. It is effective on 37% formaldehyde and takes just minutes to convert the liquid to a solid slurry. Vapors will be neutralized in around 7-10 minutes. F.C.G. comes in an easy-to-hold pack containing 680 gm - enough for even large spillages. One side of the container allows F.C.G. to be poured, the other side allows it to be sprinkled less liberally for smaller incidents. One container of F.C.G. treats approximately 500 ml of 10% Neutral Buffered Formalin Formalin Control Granules, 1.5 lb Case / Formalin Control Granules, 1.5 lb Each Section 7 Please consult your Leica Biosystems representative for availability in your region

99 07 Safety and Hygiene 97 Gloves Cut Resistant Glove The Cut Resistant Glove is manufactured from ultra high molecular weight polyethylene, one of the strongest fibers made. While handling sharp cutting instruments, the Cut Resistant Glove forms a barrier that helps protect the hand from cuts. It is lightweight, seamless and very soft to touch. They can be worn between two latex, vinyl or nitrile gloves for maximum protection against body fluid contamination. These gloves can be worn time after time and sterilized between uses, however should be replaced when signs of wear appear. Available in small, medium and large in packs of 1, 2 or 5 pairs Cut Resistant Glove, Small Pack / 5 pair Cut Resistant Glove, Small 1 Pair Cut Resistant Glove, Medium Pack / 5 pair Cut Resistant Glove, Medium 1 Pair Cut Resistant Glove, Large Pack / 5 pair Cut Resistant Glove, Large 1 Pair Cut Resistant Glove, Small Pack / 2 pair Cut Resistant Glove, Medium Pack / 2 pair Cut Resistant Glove, Large Pack / 2 pair Nitrile Glove The Nitrile Glove is made of 100% pure nitrile. It offers a higher level of resistance to nuisance nicks, cuts and abrasions and offers superior splash protection against irritating chemicals when compared to natural latex or vinyl equivalents. These gloves are just 4mls thin and provide excellent tactile sensitivity. After being worn for a short period of time, the glove conforms to your hand size for greater comfort and reduced perspiration. This special polymer formulation of nitrile does not allow adhesive label materials to stick to it. Thin nitrile exam gloves are three times more puncture resistant when tested against comparative natural latex and vinyl gloves. They are 91 2 (24cm) long, ambidextrous and have textured fingers for a better grip. They come lightly powdered with cornstarch and now are also available powderless Powdered Nitrile, Small (7 7½) Box / Powdered Nitrile, Small (7 7½) Case / 1, Powdered Nitrile, Medium (8 8½) Box / Powdered Nitrile, Medium (8 8½) Case / 1, Powdered Nitrile, Large (9 9½) Box / Powdered Nitrile, Large (9 9½) Case / 1, Powdered Nitrile, X Large (10 10½) Box / Powdered Nitrile, X Large (10 10½) Case / 1,000 Section 7

100 98 Powderless Nitrile Glove Made of 100% nitrile these durable gloves offer superior puncture resistance when compared to latex and vinyl as well as excellent tactile sensitivity, while the smaller pore size offers a superior barrier to certain chemicals. They provide an excellent alternative to latex and, as a synthetic rubber, do not have the problems associated with allergic reactions to latex. Nitrile conforms to the hand and therefore fits more comfortably and reduces hand fatigue and perspiration. They have a rolled cuff, are virtually odor free and are available in four sizes Powderless Nitrile, Small (7 7½) Box / Powderless Nitrile, Small (7 7½) Case / 1, Powderless Nitrile, Medium (8 8½) Box / Powderless Nitrile, Medium (8 8½) Case / 1, Powderless Nitrile, Large (9 9½) Box / Powderless Nitrile, Large (9 9½) Case / 1, Powderless Nitrile, Extra large (10 10½) Box / Powderless Nitrile, Extra large (10 10½) Case / 1,000 Safetyflex Steel Mesh Glove The Safetyflex Steel Mesh Glove is made up of over 10,000 interlocking stainless steel links and offers protection against knife, scalpel and saw cuts while allowing a high degree of flexibility. Preferably, the Safetyflex Glove should be worn between two Nitrile Gloves and after use the glove can be cleaned and sterilised using most commonly accepted methods. Available in petite, extra small, small, medium and large in either pairs or ambidextrous individual gloves Petite (Pair) Each Petite Each Extra small (Pair) Each Extra small Each Small (Pair) Each Small Each Medium (Pair) Each Medium Each Large (Pair) Each Large Each Section 7 Please consult your Leica Biosystems representative for availability in your region

101 07 Safety and Hygiene 99 General Hygiene Aloeponic Aloeponic is a soothing laboratory hand lotion and moisturizer made with the gel of aloe vera plants. A special formula produces a non greasy moisturizing lotion which helps soothe red, chapped skin and prevents dryness caused by the interaction of laboratory chemicals Tube, 6 oz/177 ml Case / Tube, 6 oz/177 ml Each Tube, 2 oz/59 ml Case / Bottle, 32 oz/944 ml Case / Bottle, 32 oz/944 ml Each L Absorbs L Absorbs are a strong highly absorbent, lint free alternative to paper towels and gauze. The cloth like softness and lint free surface makes them ideal for use in cover slipping and slide preparation. L Absorbs are perfect for cleaning up all liquids but are specially suited to alcohol and xylene which evaporate upon use, allowing L Absorbs to be reused. L Absorbs will readily soak up oils and liquid paraffin wax and can be used for various blotting techniques, from highly technical procedures to simple applications such as drying a block from ice during microtomy. This product is one of the most versatile and useful in the laboratory. Available in two sizes; 15 x 15 cm for cover slipping and 32 x 37 cm for general use; in cases of 600 or 1, x 14.5 (325 x 368 mm) Case / x 6 (150 x 150 mm) Case / 1,200 Leica Cryofect Cryofect is a disinfectant spray used in low temperature conditions, such as in cryostats. It is effective against bacteria, fungi and viruses such as HBV, polio or bird flu. Section 7 Easy to use, Cryofect minimizes the risks involved in dealing with potentially infectious materials. It can be used at cryochamber temperatures down to 20 C. Apply the disinfectant spray evenly on the contaminated surfaces, allow a reaction time of 15 minutes and simply wipe off Leica Cryofect, 350 ml Case / 4

102 100 MEDTROL Super Chlor 9 x 9 Disinfectant Wipe Super Chlor is a presaturated 9 x 9 ready to use disposable wipe that contains 0.525% sodium hypochlorite used for disinfecting against cross contamination in healthcare settings Super Chlor 9 x 9, Disinfectant Wipe Case / 100 Poly Apron The Poly Apron is a disposable polyethylene apron that can be used for wrap around garment protection while working in the laboratory. It is ideal for the pathologist or pathology assistant to wear while grossing specimens or by the histotechnologist during tissue sectioning. This Poly Apron has extra long ties, is lightweight, comfortable and comes packaged in a handy pull out dispenser box Poly Apron Box / Poly Apron Case / 1,000 Section 7 Please consult your Leica Biosystems representative for availability in your region

103 Surgipath Slides and Coverglass Carefully cut, ground, cleaned and inspected to ensure that they meet your quality needs. The diverse Surgipath range lets you choose a high quality slide for nearly any application on a variety of equipment. Our glass portfolio includes but is not limited to adhesive/positively charged, clipped corner and bevelled edge slides. You can also choose the coverglass you need with a range of products for both automated and manual coverslipping. Section 8

104 102 Surgipath Slides and Coverglass Create high quality slides with a complete solution from Leica Biosystems. Section 8 Leica s broad range lets you select your ideal combination of slide labeling, glass slides, mountants, coverglass and automated coverslipping. Tailor your system to meet your particular needs, and be confident that the entire process is supported by Leica Biosystems. Complete systems, completely supported by one expert organization. Bringing together all the elements is just one of the ways Leica Biosystems Total Solutions help you deliver diagnostic-quality slides. A wide variety of high quality microscope slides and coverglass. The choice is yours; select from a large range of high quality microscope slides; and be confident that you will receive Leica reliability and quality for all of your microscope slide needs. Please consult your Leica Biosystems representative for availability in your region

105 Section 8 08 SLides and CoverGlass 103 Slides & Coverslipping Apex Superior Adhesive Slide Apex Superior Adhesive Slides are microscope slides made of white glass and coated with a special adhesive material that allows the slide to be more hydrophilic. This hydrophilicity provides a better base for homogeneous covering by aqueous stains and reagents leading to consistent full slide staining Apex Superior Adhesive Slide, White Case / 1, Apex Superior Adhesive Slide, Yellow Case / 1, Apex Superior Adhesive Slide, Blue Case / 1, Apex Superior Adhesive Slide, Green Case / 1, Apex Superior Adhesive Slide, Pink Case / 1, Apex Superior Adhesive Slide, Lavender Case / 1, Apex Superior Adhesive Slide, Orange Case / 1,440 X tra Slides (Clipped Corner) X tra Slides have a permanent positive charged surface which helps to bond tissue sections and cytology preparations without the use of additional adhesives. The clipped corners provide an adhesive slide that has been optimized for use with the Leica and Sakura printer CL Clipped Corner X tra Adhesive Slide, 1.0 mm, White Case / 1, CL Clipped Corner X tra Adhesive Slide, 1.0 mm, Yellow Case / 1, CL Clipped Corner X tra Adhesive Slide, 1.0 mm, Blue Case / 1, CL Clipped Corner X tra Adhesive Slide, 1.0 mm, Green Case / 1, CL Clipped Corner X tra Adhesive Slide, 1.0 mm, Pink Case / 1, CL Clipped Corner X tra Adhesive Slide, 1.0 mm, Tan Case / 1, CL Clipped Corner X tra Adhesive Slide, 1.0 mm, Aqua Case / 1, CL Clipped Corner X tra Adhesive Slide, 1.0 mm, Lilac Case / 1, CL Clipped Corner X tra Adhesive Slide, 1.0 mm, Orange Case / 1,440

106 104 X tra Slides X tra Slides have a permanent positive charged surface which helps to bond tissue sections and cytology preparations without the use of additional adhesives. Section X tra Adhesive, 1.0 mm, White Case / 1, X tra Adhesive, 25 mm x 75 mm, 1.0 mm, White Case / 1, X tra Adhesive, 1.0 mm, Yellow Case / 1, X tra Adhesive, 1.0 mm, Blue Case / 1, X tra Adhesive Slide, 1.0 mm, Green Case / 1, X tra Adhesive Slide, 1.0 mm, Pink Case / 1, X tra Adhesive Slide, 1.0 mm, Peach Case / 1, X tra Adhesive Slide, 1.0 mm, Lavender Case / 1, X tra Adhesive Slide, 1.0 mm, Gray Case / 1, X tra Adhesive Slide, 1.0 mm, Tan Case / 1, X tra Adhesive Slide, 1.0 mm, Aqua Case / 1, X tra Adhesive, 1.0 mm, White Box / 144 (2 x 72) X75 Yellow X tra Adheseive Slides Case / 1, X75 Blue X tra Adhesive Slides Case / 1, X75 Green X tra Adhesive Slides Case / 1, X75 Pink X tra Adhesvie Slides Case / 1, X75 Peach X tra Adhesive Slides Case / 1, X75 Lavender X tra Adhesive Slides Case / 1, X75 Grey X tra Adhesive Slides Case / 1, X75 Tan X tra Adhesive Slides Case / 1, X75 Aqua X tra Adhesive Slides Case / 1, X tra Adhesive, 25 mm x 75 mm, 1.0 mm, White Box / 144 (2 x 72) X tra Adhesive, 1.0 mm, Yellow Box / 144 (2 x 72) AE X tra Adhesive Slide, 1.0 mm, Yellow (non clipped) Box / 144 (2 x 72) X tra Adhesive, 1.0 mm, Blue Box / 144 (2 x 72) AE X tra Adhesive Slide, 1.0 mm, Blue (non clipped) Box / 144 (2 x 72) X tra Adhesive, 1.0 mm, Green Box / 144 (2 x 72) AE X tra Adhesive Slide, 1.0 mm, Green (non clipped) Box / 144 (2 x 72) X tra Adhesive, 1.0 mm, Pink (non clipped) Box / 144 (2 x 72) AE X tra Adhesive Slide, 1.0 mm, Pink (non clipped) Box / 144 (2 x 72) X tra Adhesive, 1.0 mm, Peach (non clipped) Box / 144 (2 x 72) AE X tra Adhesive Slide, 1.0 mm, Peach (non clipped) Box / 144 (2 x 72) X tra Adhesive, 1.0 mm, Lavender (non clipped) Box / 144 (2 x 72) AE X tra Adhesive Slide, 1.0 mm, Lavender (non clipped) Box / 144 (2 x 72) X tra Adhesive, 1.0 mm, Gray Box / 144 (2 x 72) X tra Adhesive, 1.0 mm, Tan Box / 144 (2 x 72) X tra Adhesive, 1.0 mm, Aqua Box / 144 (2 x 72) X tra Adhesive, 1.0 mm, White Case / 1, X tra Adhesive, 1.0 mm, Yellow Canada Case / 1, X tra Adhesive, 1.0 mm, Blue Canada Case / 1, X tra Adhesive, 1.0 mm, Pink Canada Case / 1, X tra Adhesive, 1.0 mm, White Box / 144 (2 x 72) * We offer custom size slides and coverglass, please contact your local sales representative for details and availability. Please consult your Leica Biosystems representative for availability in your region

107 08 SLides and CoverGlass 105 Snowcoat Snowcoat colored marking area is printed on the most wettable surface of the slide for easy marking, color coded identification. The printed surface facilitates microscope focusing and identifies the best side to use, even by touch if necessary mm x 75 mm, 1.0 mm / 10 gross, White Case / 1, Snowcoat, 1.0 mm / 10 gross, White Case / 1, Snowcoat, 1.0 mm, White Box / 144 (2 x 72) Snowcoat, Unprinted, 1.0 mm / 10 gross, White Case / 1, Snowcoat, Unprinted, 1.0 mm, White Box / 144 (2 x 72) Snowcoat, 1.2 mm / 10 gross, White Case / 1, Snowcoat, 1.2 mm, White Box / 144 (2 x 72) Snowcoat, 1.0 mm / 10 gross, Yellow Case / 1, Snowcoat, 1.0 mm, Yellow Box / 144 (2 x 72) Snowcoat, 1.0 mm / 10 gross, Blue Case / 1, Snowcoat, 1.0 mm, Blue Box / 144 (2 x 72) Snowcoat, 1.0 mm / 10 gross, Green Case / 1, Snowcoat, 1.0 mm, Green Box / 144 (2 x 72) Snowcoat, 1.0 mm / 10 gross, Pink Case / 1, Snowcoat, 1.0 mm, Pink Box / 144 (2 x 72) Snowcoat, 1.0 mm / 10 gross, Peach Case / 1, Snowcoat, 1.0 mm, Peach Box / 144 (2 x 72) Snowcoat, 1.0 mm / 10 gross, Lavender Case / 1, Snowcoat, 1.0 mm, Lavender Box / 144 (2 x 72) Snowcoat, 1.0 mm / 10 gross, Gray Case / 1, Snowcoat, 1.0 mm, Gray Box / 144 (2 x 72) Snowcoat, 1.0 mm / 10 gross, Tan Case / 1, Snowcoat, 1.0 mm, Tan Box / 144 (2 x 72) Snowcoat, 1.0 mm / 10 gross, Aqua Case / 1, Snowcoat, 1.0 mm, Aqua Box / 144 (2 x 72) Snowcoat Clipped Corner Slides Snowcoat Clipped Corner Slides are clipped at 45º angles to help reduce glass breakage and fragmentation when loaded into slide printers. These slides have been optimized for use in the Leica and Sakura printers. Section Snowcoat Clipped Corner Slide, White Case / 1, Snowcoat Clipped Corner Slide, Blue Case / 1, Snowcoat Clipped Corner Slide, Green Case / 1, Snowcoat Clipped Corner Slide, Yellow Case / 1, Snowcoat Clipped Corner Slide, Pink Case / 1, Snowcoat Clipped Corner Slide, Tan Case / 1, Snowcoat Clipped Corner Slide, Aqua Case / 1, Snowcoat Clipped Corner Slide, Orange Case / 1,440

108 106 Pearl Snowcoat Pearl Snowcoat slides are cost efficient Snowcoat slides, available in five colors for color coded identification within the laboratory Pearl Snowcoat, White Case/1, Pearl Snowcoat, Yellow Case/1, Pearl Snowcoat, Green Case/1, Pearl Snowcoat, Pink Case/1, Pearl Snowcoat, Blue Case/1,440 Micro Slides Micro Slides use high quality sheet glass in a carefully controlled environment, implementing strict specifications and quality control procedures. Each slide is precleaned, inspected four separate times and packed in environment friendly cardboard boxes. Plain and frosted ground versions available Frosted Ground, 1.2 mm Case / 1, Plain Ground, 1.0 mm Case / 1, Frosted Ground, 1.0 mm Case / 1, Frosted Ground, 1.2 mm Box / 144 (2 x 72) Plain Ground, 1.0 mm Box / 144 (2 x 72) Frosted Ground, 1.0 mm Box / 144 (2 x 72) Specialty Microscope Slides The VCE has two vertical stripes dissecting the slide into three sections allowing vaginal, cervical and endocervical sampling on the same slide. Meanwhile, the fully frosted side is completely frosted on one side and is used for body fluid specimens. Custom size slides are available upon request VCE, 1.0 mm Case / 1, VCE, 1.0 mm Box / 144 (2 x 72) Fully Frosted, 1.0 mm Case / 1, Fully Frosted, 1.0 mm Box / 144 (2 x 72) Section 8 Please consult your Leica Biosystems representative for availability in your region

109 Section 8 08 SLides and CoverGlass 107 Beveled Edge Slides Beveled Edge Slides feature beveled edges and corners that make for easier handling. The 25 mm x 75 mm slides are good for blood smears, producing a feathered edge. Each slide is washed and carefully inspected to ensure quality Plain, beveled, 1.0 mm Case / 1, Snowcoat, beveled, 1.0 mm Case / 1, Snowcoat, beveled, 1.0 mm Box / 144 (2 x 72) Double Frost, beveled, 1.0 mm Case / 1, Double Frost, beveled, 1.0 mm Box / 144 (2 x 72) Circle Slide These slides are 3 x 1 white Snowcoat slides with two Snowcoat circles, each having a diameter of ½. These circles match up with the Cytology Funnel, which is to be used for preparation of non gyn cytology specimens Cytology slides Case / 1, Cytology slides Box / 100 Straight Edge Slides Double Frost Slides Double Frost Slides use only high quality sheet glass and are frosted on both sides of the slide. This slide is commonly used by customers who prefer a straight edge on the side of the slide compared to beveled edge slides Double Frost, 1.0 mm Case / 1, Double Frost, 1.0 mm Box / 144 (2 x 72)

110 108 Coverglass and Coverslipping Micro Coverglass Micro Coverglass features high quality precleaned borosilicate glass, chosen for its uniform thinness and flatness. This non corrosive non fogging cover glass is packed on its edge in a lint free, shock absorbing lining. Strict manufacturing specifications are controlled during the cutting, cleaning, weighing and packaging procedures. Includes dessicant packets in each ounce box. Custom sizes are available upon request. #1 Thinness: 0.13 mm 0.17 mm #1.5 Thinness: 0.16 mm 0.19 mm x 18 / #1 Case / 2, x 18 / #1.5 Case / 2, x 22 / #1 Case / 1, x 22 / #1.5 Case / 1, x 30 / #1 Case / 1, x 30 / #1.5 Case / x 40 / #1 Case / x 40 / #1 Case / x 50 / #1 Case / x 50 / #1.5 Case / x 60 / #1 Case / x 60 / #1.5 Case / x 24 / #1 Case / 1, x 24 / #1.5 Case / 1, x 30 / #1 Case / 1, x 30 / #1.5 Case / x 40 / #1 Case / x 40 / #1.5 Case / x 50 / #1 Case / x 50 / #1.5 Case / x 55 / #1 Case / x 55 / #1.5 Case / x 60 / #1 Case / x 60 / #1.5 Case / x 40 / #1 Case / x 40 / #1.5 Case / x 50 / #1 Case / x 50 / #1.5 Case / x 60 / #1 Case / x 60 / #1.5 Case / 384 Section 8 Premier Coverglass Premier Coverglass has been specially designed to work with automated cover slip machines. Extra processes to prevent sticking are employed during manufacturing and additional packaging protection has been included for extra moisture protection. The cover glass comes in four sizes, #1 Thinness: 0.13 mm 0.17 mm #1.5 Thinness: 0.16 mm 0.19 mm ACS 22 x 40 / #1 Case / ACS 22 x 50 / #1 Case / ACS 24 x 40 / #1 Case / ACS 24 x 50 / #1 Case / ACS 24 x 55 / #1 Case / ACS 24 x 60 / #1 Case / 540 Please consult your Leica Biosystems representative for availability in your region

111 Section 8 08 SLides and CoverGlass 109 Accessories Coverglass Forceps All instruments are made from premium grade, hardened stainless steel and feature a protective coating to provide extra durability and protection against rust and corrosion. Each instrument is satin matt finished to reduce eye fatiguing glare. 38DI ¼ (10.8 cm) Coverglass Forceps Each 38DI (10.2 cm) Angled, Smooth Tips Each Marking Pens Marking Pens are extremely versatile and can be used on various writing surfaces found in the laboratory. They have an extra fine point made of rigid nylon for precise marking on glass slides as well as tissue cassettes. The quick drying ink is highly resistant to aqueous based stains, alcohols, xylene and xylene substitutes. A tight fitting cap helps prevent drying of the tip. The pen barrel is ergonomically designed for ease of use Marking Pens Box / 12

112 110 Section 8 Please consult your Leica Biosystems representative for availability in your region

113 Section 9 Surgipath Specimen Transport, Storage and Archiving Histology starts the moment tissue is excised, and ends with archived slides and blocks. Leica Biosystems specimen collection and transport products help ensure you receive tissue samples quickly, well labeled and suitably fixed. Leica storage and archiving systems make sure your high-quality blocks and slides are safely stored and easy to retrieve.

114 112 Surgipath Specimen Transport, Storage and Archiving It really is a total solution when the partnership starts with specimen collection, and ends with slide and block storage. That s the benefit of working with Leica Biosystems the ideal partner for a single product, or for your entire workflow. Leica Biosystems will always be the partner you need us to be. Providing the highest level of service is just one of the ways Leica Biosystems Total Solutions help you create your ideal laboratory. Section 9 Please consult your Leica Biosystems representative for availability in your region

115 09 Specimen Transport, Storage and Archiving 113 Slide Mailers, Folders, Boxes 20 Slide Folder The 20 Slide Folder is a robust chipboard folder, handmade using a double wall construction. The front slide protection flaps are made to fold back without risk of damage to the hinge. Each slide is identified with a number and by an index printed on the front. The slides are easily removed simply by touching either end of the slide. To avoid contamination of the folder by wet sides, the two lid flaps are indented on the inside. Available per folder, in boxes of 12 folders or cases of 72 folders Slide Folder Chipboard Case / Slide Folder Chipboard Box / Slide Folder Chipboard Each 25 Slide Box The 25 Slide Box is made of high impact polystyrene to securely hold 25 slides. The slots are numbered, with an index in the lid, which is tight fitting to ensure complete protection of the slides. When the top of the slide box is removed, each slide projects above the edge of the base enabling easy removal of the slides. There is an external slot for content labels. This 25 slide box is ideal for the storage of smaller slide collections, to send slides by mail or for use by students and teachers. Available in white only as individual slide boxes or in cases of Slide Box Each Slide Box Case / Slide Box The 100 Slide Box is made of high impact polystyrene and secured with rust resistant, nickel plated clips and hinge pins. The bottom of the slide box is linked with cork. To ensure proper slide identification, each slot is numbered to correspond to the index on the inside cover. Boxes will hold 3 x 1 or 25 x 75 mm microslides. Available in 5 colors as individual slide boxes or in bulk cases of 72 (white only) Red Each Blue Each Yellow Each Green Each White Each White Bulk / 72 Section 9

116 114 One Slide Mailer Plastic and Chipboard One Slide Mailer Plastic and Chipboard has a lightweight flat construction to minimize postage expense. The flat design simplifies handling in that no special packaging is required. Mailers accommodate one 3 x 1 microslide and are reusable. Available in cases of 190 chipboards or bulk cases of 1,000 plastics Flat One Slide Chipboard Case / Flat One Slide Blue Plastic Bulk / 1,000 Plastic Slide Mailers Plastic Slide Mailers are made from shatterproof, opaque polypropylene with attached snap on lids. Rigid yet lightweight, the mailers save on postage. Available in cases of Five Slide Case / Vented Five Slide Case / Unvented Five Slide Case / Two Slide Case / 100 See Through 20 Slide Folder The See Through 20 Slide Folder is a sturdy, solvent resistant folder designed to hold 20 microscope slides featuring a clear see through flip top cover. Micro slides rest upon four raised buttons offering a pop up effect for easy retrieval and faster drying time. Multiple folders are stackable in the open or closed position. Cover flaps are secured to the base using five attachment clips for increased durability. Folders are easily cleaned using warm water and soap and can be used over and over for many years. It has a transparent cover for easy identification of slide specimen. Available in a case of 15 folders See Through 20 Slide Folder Case / Plastic Slide Tray With Flip Top Lid, White Each Plastic Slide Tray Without Lid, White Each Plastic Slide Tray With Flip Top Lid, Blue Each Plastic Slide Tray Without Lid, Blue Each Section 9 Please consult your Leica Biosystems representative for availability in your region

117 Section 9 09 Specimen Transport, Storage and Archiving 115 Two Slide Mailer Plastic and Chipboard Two Slide Mailer Plastic and Chipboard mailers utilize a flat design and accommodate two 3 x 1 microslides. The plastic variety has a snap lock feature while the chipboard mailer requires tape to keep it securely closed in transit. These mailers take up less space and make transportation easy. Chipboards are available in boxes of 100 or cases of 500. Plastics are available in boxes of 100 or bulk cases of 1, Flat Two Slide Chipboard Box / Flat Two Slide Chipboard Case / Flat Two Slide Blue Plastic Box / Flat Two Slide Blue Plastic Bulk / 1,000 UniMailer stackable The UniMailer is a stackable plastic slide mailer one slide per mailer available in white, pink, green, yellow and blue. Available in boxes of White Each Pink Each Green Each Yellow Each Blue Each Specimen Transport and Storage Cyto Jar The Cyto Jar is for the convenient collection, fixation and preservation of all cytologic specimens. The 120 ml clear leakproof container is prefilled with 45 ml of preservative containing polyethylene glycol. It can be used for rinsing aspiration needles or bronchial brushes and for the direct collection of sputum specimens. Available in cases of 50 x 120 ml jars or in bulk ml Jar Case / Empty Bulk Pack Case / 400

118 116 Multipurpose Containers Nonsterile Nonsterile Multipurpose Containers are economical, thermo formed polystyrene containers that can withstand most chemicals. Used for short or long term storage of tissue specimens, these unprinted multipurpose containers provide plenty of surface area for identification of specimens. Available in 8 oz and 16 oz with lids oz (237 ml) Cup w/lids Case / oz (473 ml) Cup w/lids Case / 100 Prefilled Formalin and Empty Specimen Jar Prefilled Formalin Specimen Jars are impact resistant, clear polypropylene jars prefilled with 10% Neutral, Phosphate Buffered Formalin. These wide mouth jars provide easy access to specimens. The caps are ribbed, with an o ring molded interior to create a tight seal, yet easy to open or close even with wet hands or gloves. The amount of formalin in the specimen jars is approximately half the volume of the jar. The jars are also available empty, either with the current OSHA or CHIP warning labels or unlabeled. The jars come in a variety of sizes. Bulk packs are also available. Section ml Prefilled Case / ml Prefilled, Mini pack Case / ml Empty, no label Case / 1, ml Empty, no label Case / ml Empty, with label Case / ml Empty, with label Case / 1, ml Prefilled, ready vial Case / ml Empty, ready vial, no label Case / ml Empty, ready vial, with label Case / ml Prefilled Case / ml Prefilled, Mini pack Case / ml Empty, no label Case / ml Empty, no label Case / ml Empty, with label Case / ml Empty, with label Case / ml Prefilled Case / ml Prefilled, Mini pack Case / ml Empty, no label Case / ml Empty, no label Case / ml Empty, with label Case / ml Prefilled Case / ml Empty, no label Case / ml Empty, no label Case / ml Empty, with label Case / ml Empty, with label Case / ml Empty, no label Case / ml Empty, no label Case / ml Empty, with label Case / ml Empty, with label Case / ml Prefilled, double liner Case / A 480 ml Prefilled, single liner Case / ml Empty, with label, double liner Case / A 480 ml Empty, with label, single liner Case / ml Empty, no label, double liner Case / 24 Please consult your Leica Biosystems representative for availability in your region

119 Section 9 09 Specimen Transport, Storage and Archiving 117 Prostate Biopsy Kits Prostate Biopsy Kits are a convenient means for the proper collection, identification and transportation of prostate biopsies. Kits contain either 8, 12, or 16 prefilled 10% neutral buffered formalin containers arranged in prelabeled positions that correlate with the area of the prostate from which the sample was taken Prostate Biopsy Kit Box / Prostate Biopsy Kit Box / Prostate Biopsy Kit Box / Prostate Biopsy Kit with Fix All Fixative Box / 12 Specimen Containers Specimen Containers are high density, polyethylene containers that range in size from 4.5 oz to the 192 oz autopsy bucket. Each specimen container has a translucent snap cap lid. These Specimen Containers are ideal for the long term storage of gross tissue. Also available is a 4.5 oz container with screw on cap Oz Cup W/Screw Cap (133 ml) Case / Ml Vial W/Snap Cap Case / Oz Cup W/Snap Cap (133 ml) Case / Oz Cup W/Lid (237 ml) Case / Oz Cup W/Lid (473 ml) Case / Oz Cup W/Lid (946 ml) Case / Oz Cup W/Lid (1.9 L) Case / Oz Cup W/Lid (2.8 L) Case / Oz Bucket W/Handles And Lid (5.8 L) Case / 8 Specimen Transport Bags with Pocket Specimen Transport Bags with Pocket are ideally suited to the interdepartmental transport of laboratory samples. The ziplock helps to contain potentially hazardous specimens while the attached full pocket offers a separate storage area for accompanying paperwork. These clear, 2 ml polyethylene bags are available as individual 6 x 9 bags with a bio hazard symbol. Supplied in dispenser boxes of 200 bags, in cases of 800 or in bulk cases of 1,000. Custom bags available on request x 9 Box / x 9 Box / x 9 Case / x 9 Bulk / 1,000

120 118 Storage Systems 8 Drawer Cabinet The 8 Drawer Cabinet is suitable for storing larger slides, transparencies and large 76 x 52 x 20 mm Super Cassette blocks. The cabinet is made of rigid steel and will stack on to the slide safe and block bank. (By custom order only) E Blue Each E Beige Each E Green Each E Gray Each 9100 Slide Cassette Storage Unit The 9100 Slide Cassette Storage Unit is designed for the short and long term storage of microscope slides and paraffin embedded cassettes. The modular design allows for stacking cassette and slide drawers into a single unit or segregated such that cassette storage and slide storage are completely separate. A base with lockable casters provides mobility to the unit should it become necessary to move the unit in the laboratory or to a storage area Cabinet Top Each Base with Lockable Casters Each Organizer with Pull Out Shelf Each Spacer Cabinet (Riser) Each Cassette Storage Unit 8 Drawers Each Cassette Storage Drawer (x4) Each Slide Storage Unit 14 Drawers Each Slide Storage Drawer (x4) Each Drawer Index Tabs (100) Each Slide Drawer Labels (1 Sheet / 14 Labels per) Each Cassette Drawer Labels (1 Sheet / 8 Labels per) Each Cardboard Storage File The Cardboard Storage File is designed to facilitate the storage of blocks and slides. This economical system is less expensive than metal filing systems but still offers the convenience of drawers for easy retrieval of file contents. Strong and lightweight due to the unique corrugated construction, the system comprises of five file boxes for either blocks or slides or a mixture of both. These are supported by an outer shell, which stabilizes and enables the units to be stacked together. The single units are 10 cm x 29 cm. The block file can hold 500 blocked out cassettes (2,500 per system) while the slide file can hold 2,000 slides (10,000 per system). Both offer the convenience of easy retrieval from partitioned drawers. By removing the central partition of the drawer, the Cardboard Storage File can be used to store larger slides or 36 blocked out and trimmed Super Cassettes. Available pre assembled or flat packed. Section Slide Storage File Case / FLAT Slide Storage File Flat Pack Case / Cassette Storage File Case / FLAT Cassette Storage File Flat Pack Case / 5 Please consult your Leica Biosystems representative for availability in your region

121 Section 9 09 Specimen Transport, Storage and Archiving 119 Cassette Storage Drawer The McCormick Cassette Drawer is a two drawer system that can be combined with additional drawers and stacked as a complete storage unit or separated for individual transport. It provides an effective means of organizing and filing histology case blocks for future reference. Constructed of high polymer plastic resin, this removable storage system houses 256 standard cassettes and approximately 500 mini cassettes. 39MC McCormick Standard Cassette Storage Drawer Case / 2 39MC McCormick Mini Cassette Storage Drawer Case / 2 Leica Storage System The versatile, durable Leica Storage System is the ideal solution for microscope slide and embedded specimen storage. The system is made up of easily configurable 48 x 48 cm metal, modular units that can be assembled in a wide variety of combinations to support a laboratory s changing needs and growth. The components are quick and easy to assemble and rearrange Unit with 14 drawers for 6,000 slides Each Unit with 7 drawers for 3,000 slides Each Separating spiral 1 inch Each Separating spiral 2 inch Each Separating rail Each Storage system for 3,000 slides, horizontal, Each 10 drawer Storage system for blocks, 8 drawer Each Base for storage drawers Each Cover for drawers Each

122 120 Modular Universal Filing System The Universal Modular Filing System allows micro slides, specimen blocks and 35 mm slides to be stored in the same unit at the same time. Easy to assemble, the Modular Universal Filing System is made from anodized aluminum for durability and appearance. This system holds a minimum of 22% more microslides and 32% more specimen blocks in the same space compared to competitive units. Each drawer has a slotted handle for easy identification and color coding. Units are available to accommodate five drawers or two drawers and are all completely interchangeable so any combination of microslides, specimen blocks or 35 mm slides can be stored Assembled five drawer cavity holds 2,500 cassette blocks or 5000 slides, five cavity Unit: 4 H, D, Each W, weight 18 lbs (10.16 cm H cm D, cm W, weight 8.17 kg) Microscope Slide Drawer Each Tissue Box Drawer with Divider + two drawers. Each Each Capacity approx blocks Base stand Each Microslide Separator Use in combination with Each Item# to insure complete drying before permanent filing Custom Drawer for 35 mm Slide Storage Fills Each (one) Cavity Holds approx mm slides depending upon thickness Assembled two drawer cavity Each Unassembled block drawer and insert. Each Section 9 Please consult your Leica Biosystems representative for availability in your region

123 Section Stains and Reagent Solutions 121 Surgipath Stains and Reagent Solutions Visualize the structures of life, and create your perfect stain. The Surgipath range includes H&E stains in a range of formulas and formats as well as a selection of cytology and special stains. For any laboratory looking for enhanced staining consistency and quality, Surgipath H&E Stains produce crisp, welldelineated hematoxylin and eosin staining, from slide to slide and kit to kit.

124 122 Surgipath Stains and Reagent Solutions The perfect partnership. Choose Surgipath Stains and reagents, performance tested with Leica automated stainers to create a complete staining system that consistently delivers quality, flexibility and productivity. Remove variability and watch your work flow seamlessly with a complete staining solution. Providing stains and stainers that work together is just one of the ways Leica Biosystems Total Solutions help you consistently deliver better quality. Surgipath Stains are recommended for use with Leica automated staining instruments, creating the perfect partnership within the laboratory. Section 10 Please consult your Leica Biosystems representative for availability in your region

125 Section Stains and Reagent Solutions 123 Infinity ST Infinity H&E Staining System Leica proudly introduces a new H&E staining system that brings with it a new science behind H&E staining. Infinity contains 5 components which have been optimized for use together on the Leica ST5010 and ST5020 stainers. All components are loaded and unloaded simultaneously for a predictable number of slides resulting in an easy to use H&E staining system. Infinity provides high quality stained slides from 1st slide to last slide, kit to kit and batch to batch through this patent pending stain technology. The ST Infinity H&E Aqueous Staining System is coming soon ST Infinity H&E Staining System 1 SelecTech SelecTech SelecTech is a hematoxylin and eosin staining system consisting of Hematoxylin 560, Blue Buffer 8, Define, Alcoholic Eosin Y 515 or Eosin Trichrome 515. SelecTech standardizes the reagents and stains used in the hematoxylin and eosin staining procedure. The reagents and stains that make up this system must pass vigorous analytical chemistry standards and performance tests. The built in quality assurance parameters assure consistent results. The reagents and stains in SelecTech are designed to complement each other to produce a crisp, well delineated hematoxylin and eosin stain. Hematoxylin 560 MX produces darker nuclear staining than standard Hematoxylin 560 and is ideal for use in dermatology laboratories when darker colorations are desired Hematoxylin 560, (500 ml) Each Hematoxylin 560, (500 ml) Case / Hematoxylin 560 MX, (500 ml) Case / Eosin Phloxine 515, (500 ml) Case / Eosin Trichrome 515, (500 ml) Each Eosin Trichrome 515, (500 ml) Case / Alcoholic Eosin Y 515, (500 ml) Each Alcoholic Eosin Y 515, (500 ml) Case / Eosin 515 LT, (500 ml) Case / Blue Buffer 8, Concentrate, (500 ml) Each Blue Buffer 8, Concentrate, (500 ml) Case / Define, (500 ml) Each Define, (500 ml) Case / Define MX aq, Concentrate (500 ml) Each Define MX aq, Concentrate (500 ml) Case / 4

126 124 SelecTech Ready to Use Blue Buffer 8 and Define MX aq SelecTech ready to use Blue Buffer 8 and Define MX aq are available in concentrates as well as ready to use formulas. The new formulas eliminate the inconvenience of pouring from concentrate stock bottles and making dilutions for working solutions Blue Buffer 8 Ready to Use, Gallon (3.8 L) Case / Define MX aq Ready to Use, Gallon (3.8 L) Case / 5 Hematoxylin Stains Gill I, II, III Three Gill formulations are available. The Gill I formula is generally recommended for cytology, while the stronger Gill III is usually preferred for use in histology. Gill II is a medium strength hematoxylin. The Gill formula hematoxylins are used in the progressive method of staining. The Gill formulations do not contain mercury. Available in various quantities Gill I, Gallon (3.8 L) Each Gill I, ½ Gallon (1.9 L) Each Gill I, Quart (946 ml) Each Gill II, Gallon (3.8 L) Each Gill II, ½ Gallon (1.9 L) Each Gill II, Quart (946 ml) Each Gill III, Gallon (3.8 L) Each Gill III, ½ Gallon (1.9 L) Each Gill III, Quart (946 ml) Each Harris Hematoxylin Harris Hematoxylin produces a deep, purple blue stain. It is generally used in regressive methods, but may also be used progressively both in cytology and histology preparations. Harris Hematoxylin does not contain mercury Harris, Gallon (3.8 L) Each Harris, ½ Gallon (1.9 L) Each Harris, Quart (946 ml) Each Section 10 Please consult your Leica Biosystems representative for availability in your region

127 Section Stains and Reagent Solutions 125 Counter Stains Eosin Eosin Y is an alcohol based, ready to use secondary stain used primarily in histology for routine hematoxylin and eosin staining. It may also be used in cytology for fast cytoplasmic staining of rush specimens also using the H&E technique. Available in various quantities Eosin, Gallon (3.8 L) Each Eosin, ½ Gallon (1.9 L) Each Eosin, Quart (946 ml) Each EA 50 EA 50 is a light green, alcohol based stain primarily used in the cytology laboratory for routine cytoplasmic staining. It is extensively quality controlled to provide a good color balance and reproducible results. Available in various quantities EA 50, Gallon (3.8 L) Each EA 50, ½ Gallon (1.9 L) Each EA 50, Quart (946 ml) Each EA 50 Modified Like the EA 50, Modified EA 50 is a light green, alcohol based stain for routine cytoplasmic staining, yet is made to a slightly different formula providing further choice to technicians. Available in various quantities EA 50 Modified, Gallon (3.8 L) Each EA 50 Modified, ½ Gallon (1.9 L) Each EA 50 Modified, Quart (946 ml) Each

128 126 EA 65 EA 65 is a light green, alcohol based stain primarily used in the cytology laboratory for routine cytoplasmic staining. It is extensively quality controlled to provide a good color balance and reproducible results. Available in various quantities EA 65, Gallon (3.8 L) Each EA 65, ½ Gallon (1.9 L) Each EA 65, Quart (946 ml) Each Orange G 6 Orange G 6 is an alcohol based stain used in the cytology laboratory to detect the presence of keratin in the cytoplasm. It is manufactured by Leica Biosystems under the strictest controls using a standard formulation. Available in various quantities Orange G 6, Gallon (3.8 L) Each Orange G 6, ½ Gallon (1.9 L) Each Orange G 6, Quart (946 ml) Each Powdered Stains Biological Dye Powder Eosin Y Biological Dye Powder Eosin Y is suitable for preparing eosin secondary stains and for use in compounding stains for Romanovsky techniques and EA formulations. The total dye content is stated on the label. It is water and alcohol soluble and certified by the Biological Stain Commission Powder Stain Eosin Y Dye, 50 g Bottle / 1 Section 10 Please consult your Leica Biosystems representative for availability in your region

129 Section Stains and Reagent Solutions 127 Biological Dye Powder Hematoxylin Biological Dye Powder Hematoxylin is used to prepare any hematoxylin formula for routine or special procedures that require nuclear staining or reaction with other tissue components. Certified by the Biological Stain Commission Powder Stain Hematoxylin Dye, 50 g Bottle / 1 Biological Dye Powder Orange G Biological Dye Powder Orange G is used in cytology for preparing OG 6 for the Papanicolaou staining method. In histology, use Orange G in methods for pancreas and pituitary or as a secondary stain in some connective tissue staining procedures. The total dye content is stated on the label. Certified by the Biological Stain Commission Powder Stain Orange G Dye, 50 g Bottle / 1 Other Dye Powders Certified by the Biological Stain Commission SS22 Orcein Synthetic, 25 g Bottle / SS23 Toluidine Blue, 25 g Bottle / 1

130 128 Special Stains Acid Fast Bacillus Special Stain Kit (AFB) Acid Fast Bacillus Stain Kit stains are used to detect and identify acid fast bacilli in tissue. Bacilli are rod shaped bacterial organisms. A primary function of this stain is to identify tuberculosis in lung tissue, as well as other bacterial bacillus infected tissue SS8 Acid Fast Bacillus Special Stain Kit (AFB) 1 Kit / Case 38016SS8A Carbol Fuchsin Solution, (500 ml) Bottle 38016SS8B Malachite Green Solution, (500 ml) Bottle Alcian Blue and PAS Special Stain Kit Combines the components of the Alcian Blue and Periodic Acid Schiff stain kits as depicted previously SS5 Alcian Blue And Pas Special Stain Kit 1 Kit / Case 38016SS4A Periodic Acid, (500 ml) Bottle 38016SS4B Schiff Reagent, (500 ml) Bottle 38016SS3A Alcian Blue (ph 2.5), (500 ml) Bottle Alcian Blue Special Stain Kit Alcian Blue is normally prepared at an acidic ph of 2.5 and is used to identify acid mucopolysaccharides and acetic mucins. Excessive amounts of non sulfated acidic mucosubstances are seen in mesotheliomas, certain amounts occur normally in blood vessel walls but increase in early lesions of atherosclerosis SS3 Alcian Blue Special Stain Kit 1 Kit / Case 38016SS3A Alcian Blue Solution (Ph 2.5), (500 ml) Bottle 38016SS3B Nuclear Fast Red, (500 ml) Bottle Section 10 Please consult your Leica Biosystems representative for availability in your region

131 Section Stains and Reagent Solutions 129 Congo Red, Amyloid Stain Kit The Congo Red, Amyloid Stain Kit is intended for use in histological detection of amyloid in tissue sections. Examination of stained tissues with conventional microscopy reveals a dull brick red coloration of amyloid. Examination utilizing polarizing microscopy reveals apple green birefringence of amyloid SS9 Congo Red, Amyloid Stain Kit 1 Kit / Case 38016SS9A Congo Red Solution, (500 ml) Bottle 38016SS9B Potassium Hydroxide, (100 ml) Bottle 38016SS4C Gill II Hematoxylin, (500 ml) Bottle Gomori Trichrome Special Stain Kit Trichrome stains are used to stain and identify muscle fibers, collagen and nuclei. They can be used to contrast skeletal, cardiac or smooth muscle. The Gomori Trichrome is a simplification of the more elaborate stains and combines the plasma stain (chromotrope 2R) and connective tissue with (Gomori s Green) to provide a brilliant contrasting stain SS1 Gomori Trichrome Special Stain Kit 1 Kit / Case 38016SS1A Bouin s Solution, (500 ml) Bottle 38016SS1B 1% Acedtic Acid, (500 ml) Bottle 38016SS1C Weigert s Hematoxylin Solution A, (250 ml) Bottle 38016SS1D Weigert s Hematoxylin Solution B, (250 ml) Bottle 38016SS1E Gomori s Green Solution, (500 ml) Bottle Gomori Trichrome Special Stain Kit Trichrome stains are used to stain and identify muscle fibers, collagen and nuclei. They can be used to contrast skeletal, cardiac or smooth muscle. The Gomori Trichrome is a simplification of the more elaborate stains and combines the plasma stain (chromotrope 2R) and connective tissue with (Gomori s Blue) to provide a brilliant contrasting stain SS2 Gomori Trichrome Special Stain Kit 1 Kit / Case 38016SS1A Bouin s Solution, (500 ml) Bottle 38016SS1B 1% Acedtic Acid, (500 ml) Bottle 38016SS1C Weigert s Hematoxylin Solution A, (250 ml) Bottle 38016SS1D Weigert s Hematoxylin Solution B, (250 ml) Bottle 38016SS2E Gomori s Blue Solution, (500 ml) Bottle

132 130 Modified GMS Silver Stain Kit The Modified GMS Silver Stain Kit is intended for use in histological observation of fungi, basement membrane and some opportunistic organisms such as pneumocystis carinii in tissue specimens SS12 Modified GMS Silver Stain Kit 1 Kit / Case 38016SS12A Modified Chromic Acid 5% aq., (500 ml) Bottle 38016SS12B Sodium Bisulfite 1% aq., (500 ml) Bottle 38016SS12C Silver Nitrate Solution 0.5% aq., (250 ml) Bottle 38016SS12D Methenamine/Borax Solution, (250 ml) Bottle 38016SS12E Gold Chloride Solution.1%, (500 ml) Bottle 38016SS12F Sodium Thiosulfate Solution 2% aq., (500 ml) Bottle 38016SS12G Light Green SF Yellow Solution, (500 ml) Bottle Schiff s Reagent Schiff s Reagent is produced in small batches, ensuring maximum consistency and shelf life. It is used in the standard Periodic Acid Schiff (PAS) reaction for neutralmucosubstances, glycogen, basement membrane and fungal cell walls. A positive reaction produces a purplish red/bright rose color Schiff Pint, (473 ml) Each Periodic Acid Schiff Special Stain Kit PAS staining is mainly used for staining structures containing a high proportion of carbohydrates such as glycogen, glycoproteins, proteoglycans typically found in connective tissues, mucus and basement membranes. Often used to stain kidney biopsies, liver biopsies, certain glycogen storage diseases in striated muscles and suspected fungal infections SS4 Periodic Acid Schiff Special Stain Kit 1 Kit / Case 38016SS4A Periodic Acid Solution, (500 ml) Bottle 38016SS4B Schiff Reagent, (500 ml) Bottle 38016SS4C Gill II Hematoxylin, (500 ml) Bottle Section 10 Please consult your Leica Biosystems representative for availability in your region

133 Section Stains and Reagent Solutions 131 Perls Prussian Blue Iron Special Stain Kit Perls Prussian Blue Iron Kit stains are used to detect and identify ferric (Fe3+) iron in tissue preparations, blood smears, or bone marrow smears. Minute amounts of ferric acid are commonly found in bone marrow and in the spleen. Abnormal amounts of iron can indicate hemochromatosis and hemosiderosis. Lack of iron identification can indicate deficient anemia SS7 Perls Prussian Blue Iron Special Stain Kit 1 Kit / Case 38016SS7A Potassium Ferrocynide Solution, (500 ml) Bottle 38016SS7B Hydrochloric Acid Solution, (500 ml) Bottle 38016SS3B Nuclear Fast Red (Kernechtrot), (500 ml) Bottle EasyDip Slide Staining System EasyDip Slide Staining Jar The staining jar being made of resistant acetal plastic will not break like most glass jars do. It will resist most staining agents including alcohol and xylene (but not phenol, iodine or ferric chloride ). The wide stable base offers greater stability while the inside is recessed, allowing for a smaller reagent volume of only 80 ml. Easy to clean and no metals to corrode. Ideal for special stains, frozen sections and special processes. Will resist temperatures between 170 C and +121 C. Autoclavable. Dimensions: 64 x 76 x 92 mm H (2 1/2 x 3 x 3 5/8 in. H) White EasyDip Slide Staining Jar, no rack Pack / Pink EasyDip Slide Staining Jar, no rack Pack / Green EasyDip Slide Staining Jar, no rack Pack / Yellow EasyDip Slide Staining Jar, no rack Pack / Blue EasyDip Slide Staining Jar, no rack Pack / 6 EasyDip Slide Staining Rack The EasyDip Slide Staining Rack will hold up to 12 microscope slides with dimensions such as 75 x 25 mm, (3 x 1 in.) and even 76 x 26 mm and with a thickness of 1.0 and 1.2 mm. The slides fit into individual slots for free passage and rapid drainage of staining fluids. Since they are placed vertically in the rack and not horizontally, their writing area will not be stained by the fluid, allowing their removal without the use of forceps. The lid completely covers the EasyDip Slide Staining Jar to minimize spill and evaporation. A handle is permanently attached to the rack for easy insertion and removal of slides without your fingers touching the solution. Available in dark gray only. Will resist temperatures between 170 C and +121 C. Autoclavable. Dimensions: 60 x 64 x 97 mm H (2 1/4 x 2 1/2 x 3 3/4 in. H) Gray Easy Dip 12 Slide Rack Pack / 6

134 132 Glass Staining Accessories Glass Coplin Jar with Lid This glass Coplin Jar may be used for staining or as a solvent preparation chamber for thin layer chromatography. It holds five single 3 x 1 (74 mm x 25 mm) slides vertically, or ten slides back to back. The screw cap liner is faced with metal foil to withstand stains and organic solvents as well as to prevent evaporation. The base is rectangular for added stability Coplin Jar Case / 12 Staining Dish, 30 Slide Unit These high quality flint glass dishes are commonly used for all routine and special staining procedures. Each dish comes with a separate fitted cover which prevents evaporation and contamination and helps to contain chemical odors. The side walls are slightly tapered to facilitate use with staining racks. Size:Top: 5 3/4 x 4 1/2 Bottom: 5 x 3 3/ Staining Dishes with lids Case / 6 Alcohols/Acids Acid Alcohol Acid Alcohol is used in histology and cytology to remove excess staining and define nuclei following hematoxylin staining in the H&E and PAP methods. In order to produce a good H&E stain with crisp nuclear detail, it is critical that certain Hematoxylins are differentiated correctly, making Acid Alcohol a highly effective solution. Available with 1% or 0.5% hydrochloric acid in 70% reagent grade alcohol, this Acid Alcohol can greatly improve reproducibility of staining results and help achieve standardization Acid Alcohol 1%, Gallon (3.8 L) Each Acid Alcohol 1%, Gallon (3.8 L) Each Section 10 Please consult your Leica Biosystems representative for availability in your region

135 Section Stains and Reagent Solutions 133 Alcohols 4 Slide Jar The 4 Slide Jar is prefilled with 20 ml of 95% Reagent Grade Ethanol. The jar is made of rigid polypropylene, has a screw cap, and is completely leak proof. This unique new product is grooved so that it will accommodate up to four microscope slides. The 4 Slide Jar comes in units of 50 in an assembled white box tray Slide Jar prefilled with 95% Reagent Grade Case / 50 Ethanol with tray Cardboard Tray Only Case / 17 Alcohols, Reagent Grade Ethanol, Isopropanol These Isopropanols and Ethanols are pure filtered and laboratory tested to ensure a consistent high quality for all formulating, processing and staining procedures in histology and cytology. The 95% and 100% reagent grade Ethanols are not classified as a controlled substance and therefore do not require record keeping. The Isopropanol is 99% anhydrous and is recommended for small tissue and biopsy processing as well as any other laboratory procedures requiring Isopropanol. Gallon sizes are supplied in nonbreakable polybottles Isopropanol, 99%, Gallon (3.8 L) Case / Isopropanol, 99%, Gallon (3.8 L) Each Isopropanol, 99%, 55 Gallon Drum (208 L) Each Ethanol, 95%, Gallon (3.8 L) Case / Ethanol, 95%, Gallon (3.8 L) Each Ethanol, 100%, Gallon (3.8 L) Case / Ethanol, 100%, Gallon (3.8 L) Each Scott s Tap Water Substitute Working Solution and Concentrate Scott s Tap Water substitute is a blueing reagent designed for histology and cytology. It blues hematoxylin gently and minimizes loss of tissue sections and cells from glass slides. Scott s Tap Water Substitute is prepared to supply a gentle but appropriate blueing solution for staining. This formulation provides rapid and precise blueing of nuclear chromatin and nuclear membranes. Decreased loss of adherence of tissue sections from glass slides is experienced with Scott s Tap Water Substitute compared with other blueing reagents Scott s, Concentrate, Pint (473 ml) Case / Scott s, Concentrate, Pint (473 ml) Each Scott s, Working Solution, Gallon (3.8 L) Each

136 134 Decalcifiers Decalcifier System Decalcifier I is a unique decalcifying solution that has the ability to fix and decalcify at the same time. Needle biopsies may be completely fixed and decalcified in one hour or less. Small bone specimens and calcified arteries may be completely fixed and decalcified in approximately 2 4 hours. It is recommend to use 20 times the volume of the specimen. Following decalcification, the specimen is ready for processing without first having to wash. Tissues decalcified in this solution cut with ease and routine H&E techniques produce excellent stained sections. Larger specimens, 3 to 5 millimeters thick, can immediately be placed in Decalcifier I to fix and initiate decalcification overnight. The following morning, if the specimen is not yet decalcified, transfer it directly to Decalcifier II to complete demineralization that same day. The Surgipath Decalcifier I II combination can save valuable time and more importantly, valuable specimens Decalcifier I, Quart (946 ml) Each Decalcifier I, Quart (946 ml) Case / Decalcifier II, Quart (946 ml) Each Decalcifier II, Quart (946 ml) Case / Decalcifier I, Gallon (3.8 L) Each Decalcifier I, Gallon (3.8 L) Case / Decalcifier I, 2.5 Gallon Cube Each Decalcifier II, Gallon (3.8 L) Each Decalcifier II, Gallon (3.8 L) Case / Decalcifier II, 2.5 Gallon Cube Each Solvents Clearene Clearene is a selected blend of terpenes formulated specifically to replace xylene and toluene in histology and cytology laboratory procedures. It is less oily than other solvent substitutes and therefore dries quickly and does not leave a residue. Clearene penetrates tissue rapidly without overhardening and is safe to use with all open and closed system tissue processors. It is miscible with alcohols, paraffins and mounting media. It contains an antioxidant to prevent stain fading. Clearene is biodegradable and offers the desirable characteristics of a good solvent but not the harmful drawbacks of aromatic hydrocarbons such as xylene and toluene based products Clearene, Gallon (3.8 L) Each Clearene, Gallon (3.8 L) Case / 4 Section 10 Please consult your Leica Biosystems representative for availability in your region

137 Section Stains and Reagent Solutions 135 ParaLast Leica ParaLast is an easy load, quick exchange solvent specifically manufactured for the Leica ASP6025 processor. Reduce hazardous vapors and paraffin consumption with the Leica ASP6025/ ParaLast system to reduce paraffin contamination during xylene free protocols. ParaLast allows xylene free processing at moderate temperatures, while ensuring prolonged wax preservation and high quality sections for morphological examination Paralast, 5L Case/4 Leica ST Ultra ST Ultra is designed to be used as a Xylene replacement during tissue embedding, deparaffination processes and coverslipping. If used for coverslipping, it can only be used with Leica CV Ultra Tin Can, 10 L Each Sub X Clearing Agent Sub X is an economical xylene substitute that is an essentially odorless and nongreasy aliphatic hydrocarbon. It can be used in place of xylene for tissue processing, deparaffinization, clearing and cleanup. Sub X is a gentle clearant which will not over harden tissue specimens. It is a non flammable liquid with a toxicity level three times safer than xylene. This selective solvent is safe to use with most plastics and tubing in open and closed tissue processors. A compatible mountant such as Sub X Mounting Medium must be used for coverslipping Sub X, Gallon (3.8 L) Each Sub X, Gallon (3.8 L) Case / 4

138 136 Xylenes, Purified Purified Xylenes are highly refined, pure filtered and laboratory tested to ensure consistent high quality for all histology and cytology procedures. Its high solvency ensures rapid and complete de waxing and clearing. Available in non breakable solvent resistant containers Xylene, Gallon (3.8 L) Case / Xylene, Gallon (3.8 L) Each Xylene, 55 Gallon Drum (208 L) Each Fixatives 10% Millonig s Modified Phosphate Buffered Formalin A 10% Millonig s Neutral Buffered Formalin is available for the histotechnologist who prefers the convenience of having a ready to use fixative at hand. The Millonig s modified buffering formulation preserves tissue specimens for both light and electron microscopy and can be used in place of the traditional 10% NBF. Each batch is quality control tested in our laboratory to ensure excellent cellular preservation and staining characteristics. Each five gallon cubitainer is supplied with a sure shut spigot % Millonig s, 5 Gallon Cube (18.9 L) Each 10% Neutral Buffered Formalin A prepared 10% Neutral Phosphate Buffered Formalin is available for the histotechnologist who prefers the convenience of having a ready to use fixative at hand. Each batch of fixative is quality control tested in our own histology laboratory to guarantee a consistent neutral ph range and excellent fixative properties. The 10% Neutral Buffered Formalin is conveniently packaged in a five gallon cubitainer with an attached handle and easy to use sure shut dispenser spigot % N.B.F., Gallon (3.8 L) Case / % N.B.F., 5 Gallon Cube (18.9 L) Each % N.B.F., 55 Gallon Drum (208 L) Each Section 10 Please consult your Leica Biosystems representative for availability in your region

139 Section Stains and Reagent Solutions 137 Buffered Formalin Concentrate 5 Buffered Formalin Concentrate 5 mixes one part to four parts water. This represents significant cost savings to the laboratory. The mixture is also more stable and eliminates the propensity to precipitate Buffered Formalin Concentrate 5, Gallon (3.8 L) Each Buffered Formalin Concentrate 5, Gallon (3.8 L) Case / 4 Fix All Fix All is a tissue fixative containing alcohol, barium chloride and 10% formalin. It is recommended for fixation of all types of tissues, including biopsies, and is particularly good for fixing dense and fatty tissues. Routine, special and immunohistochemical procedures yield excellent results. Fix All is tinted a light yellow (color). Fix All can be readily substituted for B 5 fixative. Available in 1 gallon (3.8 L), 100 x 20 ml prefilled jars or 50 x 60 ml pre filled jars Fix All, Gallon (3.8 L) Each Fix All, Gallon (3.8 L) Case / Fix All, 20 ml Prefilled Jar Case / Fix All, 60 ml Prefilled Jar Case / 50 Formaldehyde Solution This product is made available for those who desire to create their own buffered formulas or where higher than 10% product ratio to water is required. 40% by volume, 37% by weight, stabilized with methanol to inhibit polymerzation Formaldehyde Solution, Gallon (3.8 L) Case / Formaldehyde Solution, Gallon (3.8 L) Each Formaldehyde Solution, 55 Gallon Drum (208 L) Each

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