IoT Medical Application: A Bluetooth Controlled DC and Radio Frequency Ablation System for Cancer Treatment

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1 YOW! Connected IoT Medical Application: A Bluetooth Controlled DC and Radio Frequency Ablation System for Cancer Treatment Rob Clarke, Chris Gelinek RADLogic Pty Ltd 11 October 2016 RADLogic 2016, 1

2 Background IOT Medical Application Radio Frequency Ablation is a method for treating cancers (esp. liver cancers) that has been around for many years. Medical researchers have established that applying a DC bias prior to and/or during RF Ablation improves efficacy: larger areas can be treated in shorter time and cooking is better. A SA State Government Initiative called for requests for tender to investigate ways that this could be done in a controlled manner. 11 October 2016 RADLogic 2016, 2

3 Strategy IOT Medical Application Commercial RF Ablation System Design Board Level Electronics: Programmable DC Power Supply Electrode Parameter Measurement Include Control mechanism for RF Ablation Interface to communications Link Commercial Bluetooth module for communications Smartphone/Tablet is the GUI and Compute Engine Web based application development Cloud based File Management Adobe Phone Gap/Apache Cordova for conversion to self-contained App. 11 October 2016 RADLogic 2016, 3

4 RF Ablation System Second Hand Boston Scientific RF3000 IOT Medical Application Digital Control and Analog Conversion Serial Comms RF Generator & Measurement Power Supplies RF Generator Complex & Proprietary Interface Front Panel Interface Measurement, RF Output Simple keyboard Interface Control Connectors (can mimic key presses electrically) 11 October 2016 RADLogic 2016, 4

5 Board Electronics Standard 2-wire I 2 C Link for board-level comms: Programmable DC Power Supply Measurement Chip Measures Electrode Voltage, Current, Power, Impedance. I/O Ports to control RF3000 buttons, DC & RF Supply Combiner to mix DC and RF power together safely. All slaved to a highly integrated Bluetooth module Designed as a battery-powered sensor, but makes a good wiredcontroller. 11 October 2016 RADLogic 2016, 5

6 TI SimpleLink SensorTag Supports Bluetooth, 6LoWPAN or ZigBee 11 October 2016 RADLogic 2016, 6

7 Application Development BETA: Bimodal Electric Tissue Ablation IOT Medical Application 11 October 2016 RADLogic 2016, 7

8 Web Based Development IOT Medical Application 11 October 2016 RADLogic 2016, 8

9 Web Based Development IOT Medical Application Key Technologies HTML, CSS, SVG, Javascript, JSON D3 library, mainly for SVG graphing JSON for Ablation Sequence Files & Data Logs cordova_plugin_ble_central Dropbox API, TI SensorTag API Apache Cordova, Adobe PhoneGap 11 October 2016 RADLogic 2016, 9

10 System Features Programmable DC Voltage Generator 4.5V 12 Control RF Power level and duration Fully programmable Ablation Sequence Profiles: any number of steps Ablation Steps can be Constant or Gradient DC Voltage, Current or Power, Pulsed/Static Integrated DC Measurements for Voltage, Current, Power, Impedance, Temperature Data Logging of DC Measurements. File Management (Save & Load Sequences and Logs) All controllable from a phone, with a Familiar User Interface Cost < $100 (plus the RF generator & Phone) 11 October 2016 RADLogic

11 Advantages Rapid Application Development Take advantage of existing components & equipment Low Cost Development User Interface and Computation come for free. Familiar User Interface Easy to Learn Adaptable and Extensible Change or Add Features Concept applies to other Application Areas 11 October 2016 RADLogic

12 Thankyou 11 October 2016 RADLogic

13 IEEE Spectrum, September 2016 Phone-controlled Brain Stimulus Controversial method to improve Athlete s performance/abilities 11 October 2016 RADLogic 2016, 13

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