A computerized system to store and retrieve data on biological and biotechnological veterinary products of the American continent
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1 Rev. sa. lech. Off. int. Epiz., 1992, 11 (3), A computerized system to store and retrieve data on biological and biotechnological veterinary products of the American continent L.V. MELENDEZ *, D.H. VACCAREZZA *, R.B. TALBOT *, H. CAMPOS LÓPEZ ** and D. ESPESETH *** Summary: The Veterinary Biologics Information System is a project the main goal of which is to collect, analyze and manage data concerning registered veterinary biologics and biotechnological products employed to control animal diseases by the countries of the Americas. Data from each country was gathered by cataloguing each biological product on a questionnaire form. The collected data was then fed into an electronic data base system. A retrieval program was subsequently developed, allowing the user quick access to all data stored in the system. The system operates in English and Spanish and includes such information as the product name, registration number, ingredients, species for which the product is approved for use, the disease against which the product is used, names of manufacturers and distributors and other distinguishing characteristics of the product including expiry dates and withdrawal times. This computerized system, with on-line data bases which can be quickly updated, provides a dynamic answer to the question of timely information concerning veterinary biological products. KEYWORDS: Biological products - Data base - Vaccines - Veterinary information system. INTRODUCTION The Veterinary Biologies Information System is a project the main goal of which is to collect, analyze and manage data about veterinary biologies and biotechnological products employed to control animal diseases by the countries of the Americas. This project is conducted by the Inter-American Institute for Cooperation in Agriculture (IICA) with the technical assistance of the Virginia-Maryland Regional College of Veterinary Medicine of the Virginia Polytechnic Institute and State University (Va. Tech.). * Virginia-Maryland Regional College of Veterinary Medicine, Virginia Polytechnic Institute and State University, Blacksburg, Virginia , United States of America. ** Director General de Salud Animal, Secretaría de Agriculturay Recursos Hydráulicos, Recreo 14, 11 piso, Col. Actipán, Mexico D.F., Mexico. *** United States Department of Agriculture, Animal and Plant Health Inspection Services; Biotechnology, Biologies and Environmental Protection, Hyattsville, Maryland 20782, United States of America.
2 926 The project is funded by the United States Department of Agriculture (Animal and Plant Health Inspection Services; Biotechnology, Biologics and Environmental Protection) (USDA/APHIS/BBEP). This project constitutes the third phase of a larger project known as the Inter-American Compendium of Registered Veterinary Products. During 1990 and 1991, data concerning veterinary biologics and biotechnological products were stored in a data base system at Va. Tech. A Model System has been designed with the goal of facilitating the retrieval of data on veterinary biologies and biotechnological products within the member countries of the IICA and the Pan American Health Organization (PAHO/WHO). Data from each participating country is gathered by cataloguing each biological product on a questionnaire form. This data is then fed into data bases specific to each country. This Model System allows the user quick access to all data stored in the data base. The available data ranges from listings of all products registered in a particular country and specific information about manufacturers (such as distributor lists) to listings of products used to combat a specific disease and products which contain a certain ingredient. Due to the international nature of the data with which the system deals, the Model System proposed operates both in English and Spanish. Data received in Spanish from Latin American countries is translated into English and made available to non Spanish-speaking users. The data received in English, in turn, is translated into Spanish. The Model System is completely menu-driven, allowing the user to search for a product utilizing many different characteristics of the product, including the following: the product name (if known) - the official registration number of the product (if applicable) the name of an ingredient present in the product the name of the species for which the product is utilized the disease against which the product is used the name of the manufacturer of the product. Users may also conduct a search for a product using the date of appioval (registration) as the scope of the query. The Model System allows for the retrieval of data from a single country or from all American countries at once. Multiple-countiy searching is useful in determining which countries support particular products. Information such as accurate listings of products used against a certain disease or for a certain species can be retrieved quickly. From this point, a user can then narrow the scope of the search to the handful of countries or the single country pinpointed. Switching from multiple country to single-country searches is simple, due to the menu format used in the system. The mam menu allows the user to choose between single and multiple-country searches.
3 927 NATIONAL DATA RETRIEVAL After selecting the single-country search option from the main menu, the user is presented with a list of the countries participating in the project (all American countries). At this point, the user inputs the number of the country desired. All searches will be performed on the data base for the selected country until the user selects a different country or terminates the session. Once a country is selected, the next menu presents the user with a list of the types of searches which can be performed, along with an option to change the selected country at any time. Types of searches include: search for a trade-name (if known) - search for an official registration number (if known and applicable in the selected country) - search for an ingredient present in the product - search for a species search for products utilized against a certain disease. Two other options also appear on this menu: list trade names and official numbers, and information on a manufacturer. Each of these two options, when chosen, reveals a secondary menu allowing the user to narrow the search. The first option (list trade names and official numbers) reveals a menu which allows for the listing of all products registered in the country or for the listing of products registered in a given year, on a given date, or after a given date. The second choice (information on a manufacturer) reveals a secondary menu which allows for a listing of all manufacturers with products registered in the country, a list of the products of a certain manufacturer, or a list of the distributors for a specific manufacturer. The output of all searches at this level is a standardized list of the products (tradenames) which match the search query, except in the case of manufacturer and distributor lists where the company names are listed instead of product trade names. From this product list, the user need only input the number given next to the product trade name in order to view all the information available for a particular product. This product information includes the generic name (ingredients), approval and expiry dates, manufacturers and distributors, species, administration routes, dosage information, indications for use, and much more, including elimination times and methods of production. The Model System also provides the user with the opportunity to further narrow searches to provide the exact information required. After a search is conducted and the output list is given, a secondary menu is presented which allows the user to conduct further searches on the information returned from a previous search. For example, a user wishing to see a list of all of the products registered in a particular country which are utilized to combat rabies and approved for use in bovines, may simply invoke a Disease search where the output returned will reveal all the products registered in the country which are utilized against rabies. Given this list of products, the user can then invoke a Species search from the secondary menu to search for products approved for use in bovines from the list returned by the first (Disease) search. The output list returned from this second search will contain the names of the products registered in the country which are utilized to fight rabies and approved for use in bovines, the exact information required.
4 928 INTERNATIONAL DATA RETRIEVAL The main menu also provides an option for multiple country searches. Selecting this option reveals a secondary menu which lists the different types of searches which can be performed on all of the thirty data bases at once. These searches include: - search for an ingredient present in the product search for products utilized against a certain disease search for products utilized for a specific species. Selecting any of these three searches will provide the same type of results. After inputting the ingredient, disease, or species for which the user wishes to search, a secondary screen appears with the name of each of the thirty countries. Next to each country name, a number will appear which signifies the number of products matching the query. At the bottom of the screen, a total of all the matches is presented. When the search is completed, a list of products is given as for the single country searches, with the exception that a country name appears next to each product name. This helps to clarify which products belong to which country. Again, as in the single-country searches, a user need only input the number of a particular product and a screen will appear carrying all the relevant specific data. Multiple-country searches are useful in making precise comparisons between countries with respect to the use of veterinary biological products in controlling certain animal diseases. Through the multiple-country search option, a user can specify the countries (if not all thirty) on which to conduct searches. This allows the user to conduct limited and more specific searches on the countries of interest, without having to sort through irrelevant information. This option increases the versatility of the system by allowing a user to specifically define the scope of searches as well as the precise data bank to be examined. The information obtained from each of the participating countries lends itself well to storage using a data base format. Each entry on the questionnaire can be broken up into fields, and a separate record is made for each registered product on the basis of these fields. The choice of data base software took into account such specific characteristics as the support of an independent programming language through which a system could be developed to manipulate the stored data. "Dbase III plus" was the software chosen. A separate system was developed to input the information into the data bases, in order to ease the difficult tasks of data entry for a large number of products and standardization of the data. The Model System is a stand-alone system; it is not necessary for the user to be familiar with Dbase III plus 01 even to have a copy of the software to use the system. The program runs from a DOS prompt on any IBMcompatible machine. It can operate from a floppy diskette or be loaded onto a hard disk to enhance the performance. Data bases can be maintained on floppy diskettes for portability 01 they can also be loaded onto the hard disk to further increase the speed of execution.
5 929 CONCLUSION This Model System is being developed in order to enhance and simplify the retrieval of data accumulated as a result of the project to catalogue all registered veterinary biological products on the American continent. The driving force behind the development of a computerized system to store this data was the need to maintain up-to-date information on veterinary biologics. Publications provide all the necessary information, but they quickly become obsolete. A computerized system with on line data bases which can be constantly updated provides a dynamic answer to the question of timeliness. Through the use of the technology available today, a system to catalogue all the registered biological products in the Americas can be kept up to-date with a minimal amount of effort and can not only be utilized to benefit the American continent, but can also be easily adapted to perform the same functions for biological and biotechnological products for both animal and human use in other regions of the world. ACKNOWLEDGEMENT Support for this project was provided by USDA/APHIS/BBEP - Grant No GR. LE FICHIER INFORMATIQUE POUR LE CLASSEMENT ET LA CONSULTATION DES DONNÉES SUR LES PRODUITS VÉTÉRINAIRES BIOLOGIQUES ET BIOTECHNOLOGIQUES DANS LES AMÉRIQUES. L.V. Meléndez, D.H. Vaccarezza, R.B. Talbot, H. Campos López et D. Espeseth. Résumé : Le «Système d'information sur les produits biologiques vétérinaires» a pour objectif l'obtention, l'analyse et le traitement des données concernant les produits biologiques et bio technologiques à usage vétérinaire enregistrés et utilisés pour la lutte contre les maladies animales dans les pays du continent américain. Les données sur les produits biologiques utilisés dans chaque pays sont obtenues grâce à des questionnaires ad hoc. Les informations qui en découlent sont introduites dans la base de données. Celles ci peuvent alors être rapidement traitées ou extraites de la base, grâce à un programme informatique spécialement conçu à cet effet. Le système ainsi mis au point fonctionne en anglais et en espagnol ; les données qu'il comporte sont, entre autres, le nom du produit, son numéro d'enregistrement, ses composants, la ou les espèces animales pour lesquelles il a été homologué, la maladie pour laquelle il est recommandé, le nom du fabricant et des distributeurs, ainsi que la date de péremption et le temps d'attente, etc. Ce système informatique présente l'avantage de pouvoir être mis à jour régulièrement et de fournir très rapidement les informations demandées. MOTS CLÉS : Base de données - Produits biologiques Système d'information vétérinaire - Vaccins.
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