Preface. Med. Phys. 35(9), , Mechanical QA. Radiation Survey Mechanical tests Light radiation Table, Collimator, Gantry Jaws.

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AAPM-SAM-2012-Das (1) Beam Data Collection and Commissioning for Linear Accelerators: Technical Considerations and Recommendations Preface Indra J. Das, PhD, FAAPM, FACR, FASTRO Department of Radiation Oncology Indiana University of School of Medicine & Indiana University Health Proton Center Indiana Med. Phys. 35(9), 4186-4214, 2008 Mechanical A Planning for Commissioning Data Radiation Survey Mechanical tests Light radiation Table, Collimator, Gantry Jaws Table Collimator Gantry MLC 2008 Imaging parameters Other as TG-142 4udrant Independent Jaw Test

AAPM-SAM-2012-Das (2) Planning for Commissioning Time Rational For Commissioning Beam Data Rational For Not Using Golden Data Time= [(PDD + 5 profiles)/beam energy] x ( open + 4 wedges) x 60 points/scan x [(1 s/pts + (1s/movement and delay)] x (15 fields x 2 energies) First, it is not evident that manufacturing procedures for all linear accelerators have produced a level of reproducibility acceptable for clinical use. For example, variations in beam parameters have been noted between beams with the same nominal energies. Second, on-site changes made during installation and acceptance of the user s accelerator e.g., changes in beam energy and/or profiles from beam steering will not be modeled in the golden data. Third, the beam characteristics of the soft wedges are made by moving jaws that depend on the speed parameters of the jaws and a deviation at site could affect the beam profile of the soft wedge. TG-106 Fourth, although acceptable agreement with the golden data set may be found in individual checks, it may be that some clinical setups will have multiple errors, which combine to produce unacceptable results. Hrbacek, et al Med. Phys. 34, 2917 2927, 2007. 10 5 s 30 h Rational For Not Using Golden Data Definition of Detectors Setting Water Tank & Detector x i x <Δ, x i Δ =? (0.5, 1.0 0r 2%) Standard chamber 10 1 cm 3 The active volume for a standard Farmer-type ionization chamber is on average 0.6 cm 3. Minichamber 10 2 cm 3 The active volume for a mini-ionization chamber is on average 0.05 cm 3. Microchamber 10 3 cm 3 The active volume for a microionization chamber is on average 0.007 cm 3 and ideally suited for small field dosimetry such as radiosurgery,gamma knife, CyberKnife, and IMRT Air Water 1 2 3 4 5 Hrbacek, et al uantitative evaluation of a beam-matching procedure using one dimensional gamma analysis, Med. Phys. 34, 2917 2927, 2007.

AAPM-SAM-2012-Das (3) Know Your Connectors Understand Detector, Connector & Cable uality of Cables Srivastava et al, SU-GG-T-270, 2010 Setup and Possible Errors Electrometer Null Setting Cable subtraction Proper bias >300 V for ion chamber 100 V for diamond 0 v for all diodes Proper gain Proper mode Choose Consistent & Correct Polarity

AAPM-SAM-2012-Das (4) Chambers & Gain Selection of detector for beam data Choice of Detector Orientation Radiation beam Chamber Orientations Y Z X Z X Y Scan Direction Detector Orientation 6MV, 2x2 cm2 field, Illustration of chamber volume effects 110 100 Diode, dmax 90 PTW Pinpoint, dmax 80 RK chamber, dmax Relative Dose 70 60 50 40 30 20 10 0 0 0.5 1 1.5 2 Distance Off Axis (cm)

AAPM-SAM-2012-Das (5) 6 MV 60 Deg Wedge, 10 cm depth: water vs Profiler 250 18 MV 60 Degree Wedge, 10 cm depth, 100 cm SAD: Water vs Profiler 200 Scanning Speed Diode Array Profile Water Profile 200 Diode Array profile Water Profile 180 160 140 Relative Dose 150 100 Relative Dose 120 100 80 60 50 40 20 0-20 -15-10 -5 0 5 10 15 20 Distance Off Axis(cm) 0-20 -15-10 -5 0 5 10 15 20 Distance Off Axis(cm) Scanning Speed Percent Depth Dose 100 80 60 40 20 Arithmetic Mean (AM) smoothing: 60 Degree Wedge PDD Unsmoothed AM x 1 AM x 2 AM x 3 AM x 5 0 0 5 10 15 20 25 30 35 Depth(cm)

AAPM-SAM-2012-Das (6) Future of Beam Data Commissioning Monte Carlo Codes Standardization of linear accelerators Monte Carlo based commissioning Newer Radiation Detectors & Cables Newer Scanning Systems Smart algorithms Aubin et al., Med Phys, 37(5), 2279-2288, 2010 Aubin et al., Med Phys, 37(5), 2279-2288, 2010 Simulation of intensity at target Simulated Profiles Profiles for different fields Aubin et al., Med Phys, 37(5), 2279-2288, 2010 Aubin et al., Med Phys, 37(5), 2279-2288, 2010

AAPM-SAM-2012-Das (7) Depth Dose Simulation Aubin et al., Med Phys, 37(5), 2279-2288, 2010 Detectors Detector Manufacturer Type volume SFD Scanditronix Photon diode 1.7x10-5 cm 3 PFD Scanditronix Photon diode 1.9x10-4 cm 3 Exradin A-16 Standard Imaging Ion chamber 0.007cm 3 Wellhofer-IC4 Scanditronix Ion chamber 0.40 cm 3 Pinpoint PTW Ion chamber 0.015cm 3 0.125cc PTW Ion chamber 0.125cm 3 0.3cc PTW Ion chamber 0.3 cm 3 0.6cc PTW Ion chamber 0.6 cm 3 Diamond PTW Diamond 0.003cm 3 Markus PTW Parallel plate 0.055cm 3 Edge Detector Sun Nuclear Diode 10-5 cm 3 Other Relative sensitivity Sensitivity vs Volume of Detectors 140 130 PFD 120 110 100 90 80 0.6 cc 70 60 50 40 SFD 0.3cc 30 20 0.125cc 10 A-16 PinPoint Markus IC4 0 1.0E-04 1.0E-02 1.0E+00 1.0E-03 1.0E-01 Volume (cm 3 ) Magna-Fields 200x200 cm 2 Treatment Fields Traditional Fields 40x40 cm 2 4x4 cm 2 Small Field 4x4 cm 2 0.3x0.3 cm 2 Advance Therapy Fields SRS/SRT Gamma Knife Cyber-Knife Tomotherapy IMRT What is a Small Field? Lack of charged particle Dependent on the range of secondary electrons Photon energy Collimator setting that obstructs the source size Detector is comparable to the field size Views of Source Sizes Jaffray et al, Med Phys 20, 1417-1427 (1993).

AAPM-SAM-2012-Das (8) Definition of Small Fields Calculation of Fluence Map Elements Dosimetry Raytrace to calculate attenuation or use approximate penumbra shape For each element, find the contributions from the relevant sources Dominating effect: The width and shape of the source Absolute Dose Relative Depth Dose [D(r,d)/D(r,dm)] TMR Profiles Output, S cp (total scatter factor), [D(r)/D(ref)] Das et al, Med. Phys. 35, 206-215, 2008 Courtesy Ahnesjö POI-eye-view of the source! Relative dose at dmax 6 MV; Central Axis 1.1 1.0 0.9 0.8 0.7 0.6 Scanditronix-SFD Scanditronix-PFD 0.5 Exradin-A16 0.4 PTW-Pinpoint PTW-0.125cc 0.3 PTW-0.3cc PTW-0.6cc 0.2 PTW-Markus 1.1 0.1 Wellhofer-IC4 1.0 0.0 0.9 0 1 2 3 4 5 6 7 8 9 10 11 Field Size (cm) 0.8 0.7 0.6 0.5 0.4 0.3 0.2 0.1 0.0 Das et al, TG-106, Med Phys, 35, 4186, 2008 Relative dose at dmax Field Size Limit for Accurate Dose Measurements with Available Detectors 15 MV; Central Axis Scanditronix-SFD Scanditronix-PFD Exradin-A16 PTW-Pinpoint PTW-0.125cc PTW-0.3cc PTW-0.6cc PTW-Markus Wellhofer-IC4 0 1 2 3 4 5 6 7 8 9 10 11 Field Size (cm) D = M Ω k k f w, f clin, f clin, Relative Dosimetry f N DW, o k, o M ( D ) ( ) clin w, M clin M clin f f f = M ( D ) ( ) w, / M M f ( Dw, )/( M ) ( Output ) clin w, clin rel ( Dw, )/( M w, ) (Re ading rel =, f clin, = = ) ( S = ( S w, air ) w, air ) f k f, f ref, / clin, f k f clin, P P New Data on Correction Factor Pantelis et al, Med Phys, 37(6), 2369-2378, 2010

AAPM-SAM-2012-Das (9) clin clin f, f, k Correction factor 1.16 1.14 1.12 1.10 1.08 1.06 1.04 1.02 1.00 0.98 0.96 0.94 0.92 0.90, f k clin, Siemens; PTW diode 60012 Elekta; PTW diode 60012 Siemens; Exradin A16 Elekta; Exradin A16 Siemens; Sun Nuclear Dedge "Elekta; Sun Nuclear Dedge" Siemens; PTW Pinpoint 31014 Elekta; PTW Pinpoint 31014 Siemens; PTW microlion Elekta; PTW microlion 0 5 10 15 20 25 30 35 Field size (mm) New Data on Correction Factor Chung et al, Med Phys, 37(6), 2404-2413, 2010 k is not Constant in Small Field Kawachi et al, Med Phys, 35, 4591-4598, 2008 Depth Dose & Source Size Profile & Source Size Comparison of Large Tank and Small SRS Cylinder Tank for SRS, TMR & Profiles Moving Tank System for TMR Sham et al, Med Phys, 35, 3317-3330, 2008 Sham et al, Med Phys, 35, 3317-3330, 2008 ARM Inc., Port Saint Lucie, FL 34983

AAPM-SAM-2012-Das (10) Direct TMR Data Acquisition No SSD to SAD calculations required, No cubic spline fit of a limited number of fixed data points needed Calculated TPR ~2% less at depth Cubic spline fit of 12 data points 3D Scanner (Sun Nuclear) Setup Subjectivity Automatic leveling, water surface detection and beam center detection No tank shifts Detector orientation/resolution 3D Scanner design always using the short dimension of chamber to scan Time Setup is faster and more accurate No tank shifts Smaller tank fills and drains faster Scanner Orientation Advantage Nikesch et al, CyberKnife Center, Palm Beach, FL Sun Nuclear 3D Scanner 1 2 3 2 1 1. Ring drive maintains consistent scanning direction 2. Diameter drive has maximum scanning range of 640mm 3. Vertical drive has maximum travel of 400mm Conclusions Golden Data should be taken as a reference only Understand time and amount of data to be taken View each parameters properly, double check by another individual Use proper detector for each type of data collection Set optimum speed for scanning, do not rush -Conclusions Understand the limits and measuring condition uestion every unusual data set Do not smooth data too much Write report for future reference Future technology & resources could help commissioning simpler

AAPM-SAM-2012-Das (11) Thanks