A Modified Adaptive Fuzzy C-Means Clustering Algorithm For Brain MR Image Segmentation

Transcription

1 A Modfed Adaptve Fuzzy C-Means Clusterng Algorth For Bran MR Iage Segentaton M. Ganesh, V. Palansay Electroncs and Councaton Engneerng, Info Insttute of Engneerng, Cobatore, Talnadu, Inda. Abstract Fuzzy c-eans (FCM) clusterng has been wdely used n age segentaton. However, n spte of ts coputatonal effcency and wde spread popularty, the FCM algorth does not take the spatal nforaton of pxels nto consderaton, and hence ay result n low robustness to nose and less accurate segentaton. In ths paper, a odfed adaptve fuzzy c-eans clusterng (AFCM) algorth s presented for fuzzy segentaton of agnetc resonance (MR) ages. To estate the ntensty nhoogenety, the global ntensty s ntroduced nto the coherent local ntensty clusterng algorth and takes the local and global ntensty nforaton nto account. The proposed ethod has been successfully appled to recorded MR ages wth desrable results. Our results show that the proposed AFCM algorth can effectvely segent the test ages and MR ages. Coparsons wth other FCM approaches based on nuber of teratons and te coplexty deonstrate the superor perforance of the proposed algorth. 1. Introducton All anuscrpts ust be n Englsh. These gudelnes nclude coplete descrptons of the fonts, spacng, and related nforaton for producng your proceedngs anuscrpts. Magnetc resonance (MR) agng has several advantages over other edcal agng odaltes, ncludng hgh contrast aong dfferent soft tssues, relatvely hgh spatal resoluton across the entre feld of vew and ult-spectral characterstcs. Therefore, t has been wdely used n quanttatve bran agng studes. Quanttatve voluetrc easureent and three-densonal (3D) vsualzaton of bran tssues are helpful for pathologcal evoluton analyses, where age segentaton plays an portant role. The sze alteratons n bran tssues often accopany varous dseases, such as schzophrena [1]. Thus, estaton of tssue szes has becoe an extreely portant aspect of treatent whch should be accoplshed as precsely as possble. Ths creates the need to properly segent the bran MR ages nto gray atter (GM), whte atter (WM) and cerebrospnal flud (CSF) and also to dentfy tuors or lesons, f present []. The an dffcultes n bran segentaton are the ntensty nhoogenetes and nose. In fact, ntensty nhoogenety occurs n any real-world ages fro dfferent odaltes [3, 4]. In partcular, t s often seen n edcal ages, such as X-ray radography/ toography and MR ages. For exaple, the ntensty varaton across the age, whch arses fro rado-frequency (RF) cols or acquston sequences. Thus the resultant ntenstes of the sae tssue vary wth the locatons n the age. The nose n MR ages s dstrbuted and can affect sgnfcantly the perforances of classfcaton ethods. The best solutons consst of ether flterng the age pror to classfcaton or ebeddng spatal regularzaton nsde the classfer tself. Segentaton subdvdes an age nto dfferent regons or objects based on the nforaton found about objects n agng data. In the segentaton of edcal ages, the objectve s to dentfy dfferent regons, organs and anatocal structures fro data acqured va MRI or other edcal agng technque. Intally segentaton has been done based anually by huan experts. But anual segentaton s a dffcult and te consung task, whch akes an autoated breast cancer segentaton [15] ethod desrable. The autoated segentaton [16] of MR ages nto anatocal tssues, fluds, and structures s an nterestng feld n edcal age analyss. Autoatc tuor segentaton based on 1

2 artfcal ntellgence [10] technques was proposed to prove the edge detecton accuracy. In the last decades, fuzzy segentaton algorths, especally the fuzzy c-eans algorth (FCM), have been broadly used n the age segentaton [9] and such a success ostly attrbutes to the ntroducton of fuzzness for the belongngness of each age pxel. Fuzzy c-eans [14] allows for the ablty to ake the clusterng ethods able to retan ore nforaton fro the orgnal age than the crsp or hard segentaton ethods [8]. Clusterng s used to panel a set of gven observed nput data vectors or age pxels nto clusters so that coponents of the sae cluster are slar to one another than to ebers of other clusters where the nuber of clusters s usually predefned or set by soe weght crteron or a pror knowledge. Fuzzy c-eans segentaton [17] ethods are havng sgnfcant proft n segentaton of edcal ages, because they could retan a lot ore nforaton fro the orgnal age than hard c-eans segentaton ethods. The an advantage n fuzzy c- eans algorth s t allows pxels to belong to ultple clusters wth reasonable degrees of ebershp grades. However, there are soe dsadvantages n usng fuzzy c-eans; the ebershp of an object has not strong enough or sgnfcantly hgh for a partcular cluster, t eans that the equaton of calculatng ebershp s not an effectve, and soetes the equaton for updatng prototypes has ncapable to work wth data whch greatly affected by nose. Thus the equaton for updatng prototypes leads the result of clusterng ght be uncorrected. The an reason for underlyng drawbacks of above s, fuzzy c- eans eploys based on exsted Eucldean dstance easures. Coputer aded bran tuor segentaton syste s an portant applcaton n edcal age analyss. Developng a edcal age analyss syste not only can lghten the workload and decrease the errors of the doctors, but also can provde a quanttatve easure about varaton of the bran tuor throughout ts whole therapeutc treatent. However, t s stll a dffcult proble to autoatcally segent bran tuor regons fro MRI ult-sequences because of any exstng types of tuors wth orphologcal varablty, a varety of shapes and appearance propertes aong ndvduals, the deforaton near the structures n the bran whch results n an abnoral geoetry also for healthy tssues, and lack of pror knowledge about the. Therefore, t s practcally eanngful to focus on se-autoatc or fully-autoatc segentaton ethods on ultple MRI scans for edcal research, dsease ontorng, therapeutc control and so on. Dfferent MRI sequences fro dfferent exctatons can respectvely provde dfferent and partly ndependent nforaton about dfferent tssues, and reflect pathologc nforaton about the tuors n the bran. As a tuor conssts of dfferent bologc tssues, one type of MRI cannot gve coplete nforaton about abnoral tssues. Cobnng dfferent copleentary nforaton can enhance the segentaton of the tuors. Therefore, radology experts always cobne the ult-spectral MRI nforaton of one patent to ake a decson on the locaton, extenson, prognoss and Clusterng s a process of classfyng objects or patterns n such a way that the saples n the sae group are ore slar than the saples n dfferent groups. Based on the fuzzy theory, Zadeh [5] proposed the fuzzy clusterng ethod, whch produces the dea of partal ebershp of belongng. As a soft clusterng ethod, fuzzy clusterng has been extensvely studed and successfully appled to age segentaton. One of the ost portant and wdely used fuzzy clusterng ethods s the fuzzy c-eans (FCM) algorth, whch was frst proposed by Dunn [6] and prooted as the general FCM clusterng algorth by Bezdek [7]. The an purpose of the FCM algorth s to ake the vector space of a saple pont be dvded nto a nuber of sub-spaces n accordance wth a dstance easure [8]. However, the FCM algorth does not take the local spatal property of ages nto consderaton, and hence suffers fro hgh senstvty to nose. To prove ts robustness, any odfcatons to the FCM algorth that ncorporate spatal nforaton nto clusterng have been proposed. Pha et al. [8] suppleented the FCM objectve functon wth a penalty ter and resulted n spatally soothed ebershp functons.. Related Work.1. Conventonal FCM clusterng algorth Multresoluton segentaton s a botto up regon ergng technque startng wth one-pxel

3 objects. In nuerous subsequent steps, saller age objects are erged nto bgger ones. Throughout ths par wse clusterng process, the underlyng optzaton procedure nzes the weghted heterogenety of resultng age objects, where n s the sze of a segent and h an arbtrary defnton of heterogenety [3]. In each step, that par of adjacent age objects s erged whch stands for the sallest growth of the defned heterogenety. If the sallest growth exceeds the threshold defned by the scale paraeter, the process stops. Dong so, ult-resoluton segentaton s a local optzaton procedure. The entropy based ethodology for segentaton of satellte ages s perfored as follows. Iages are dvded nto square wndows wth a fxed sze L, the entropy s calculated for each wndow, and then a classfcaton ethodology s appled for the dentfcaton of the category of the respectve wndows. The classfcaton approach can be supervsed or non-supervsed. Supervsed classfcaton needs a tranng set coposed by wndows whose classes are prevously known (prototypes), such as rural and urban areas. Gven a data set X = {x1,x,.xn}, where the data pont xj Rp(j = 1,..., n), n s the nuber of data, and p s the nput denson of a data pont, tradtonal FCM [3] groups X nto c clusters by nzng the weghted su of dstances between the data and the cluster centers or prototypes defned as constrant for the optzaton proble and t reduces heterogenety ost over the scene followng a pure quanttatve crteron. Its an dsadvantage s that t does not use the treatent order and bulds frst segents n regons wth a low spectral varance leadng to an uneven growth of the age objects over a scene. It also causes an unbalance between regons of hgh and regons of low spectral varance. Coparson of global utual fttng to local utual fttng results show neglgble quanttatve dfferences, the forer always perfors the ost hoogeneous erge n the local vcnty followng the gradent of the degree of fttng. The growth of age objects happens sultaneously as well n regons of low spectral varance as n regons of hgh spectral varance. KFCM confnes that the prototypes n the kernel space are actually apped fro the orgnal data space or the feature space. That s, the objectve functon s defned as j ( j ) ( ) () 1 j1 Q u x o The objectve functon n (6) s then reforulated as j j (3) 1 j1 Q u (1 k( x, o )) j j (1) 1 j1 Q u x o Here, s the Eucldean dstance. uj s the x j ebershp of data belongng to cluster, whch s o represented by the prototype.the constrant on c u j s 1 u j 1.. Kernel FCM (KFCM) and s the fuzzfcaton coeffcent. When applyng the KFCM fraework n age-segentaton probles, the ultresoluton segentaton ay end up wth local optzaton procedure. Global utual fttng s the strongest Here, (1 k( x, o )) j can be consdered as a robust dstance easureent derved n the kernel space..3. Multple KFCM (MKFCM) The applcaton of ultple or coposte kernels n the FKCM has ts advantages. In addton to the flexblty n selectng kernel functons, t also offers a new approach to cobne dfferent nforaton fro ultple heterogeneous or hoogeneous sources n the kernel space. Specfcally, n age-segentaton probles, the nput data nvolve propertes of age pxels soetes derved fro very dfferent sources. Therefore, we can defne dfferent kernel functons purposely for the ntensty nforaton and the texture nforaton separately, and we then cobne these 3

4 kernel functons and apply the coposte kernel n MKFCM to obtan better age-segentaton results. Exaples that are ore vsble could be found fro ultteporal reote sensng ages. The pxel nforaton n these ages nherts fro dfferent teporal sensors. As a result, we can defne dfferent kernels for dfferent teperature channels and apply the cobned kernel n a ultple-kernel learnng algorth. The general fraework of MKFCM as to nze the objectve functon j co ( j ) co ( ) (4) 1 j1 Q u x o k s a polynoal kernel for the spatal nforaton k (x, x j ) = (x x j + d) (8) If kco = k1 + αk s the coposte kernel, the nzed objectve functon of the MKFCM s derved as j co( j ) (9) 1 j1 Q u x o For exaple, the nput age x j s set to be xj = [xj, xj, sj ] R3, the sae as the thrd varant of MKFCM, then the coposte kernel s desgned as To enhance the Gaussan-kernel-based KFCM-F by addng a local nforaton ter n the objectve functon j j j j 1 j1 1 j1 (5) Q u (1 k( x, o )) u (1 k( x, o )) where xj s the ntensty of pxel j. In the new objectve functon, the addtonal ter s the weghted su of dfferences between the fltered ntensty xj (the local spatal nforaton) and the clusterng prototypes. The dfferences are also easured usng the kernelnduced dstances. Such knd of enhanced KFCMbased algorth s denoted as AKFCM (wth A standng for addtonal ter). It s worth notng that k1or k n the frst varant of MKFCM-K-based age segentaton can be changed to any other Mercer kernel functon for the nforaton related to age pxels. Ths epowers the flexblty to the segentaton algorth n kernel functon selectons and cobnatons. For exaple, a coposte kernel that jons dfferent shaped kernels can be defned as k co = k 1 + αk (6) where k1 s stll the Gaussan kernel for pxel ntenstes k 1 (x, x j ) = exp( x x j /r ) (7) k w k w k w k (10) L b b b The MKFCM algorth evaluates the centrods so as to nze the nfluence of outlers. Unlke FCM, t does not attept fuzzfcaton for eleents havng ebershp values above the calculated threshold. Ths reduces the coputatonal burden copared to FCM; also there s an absence of external user-defned paraeters. The reoval of ths ntal tral and error factor akes MKFCM ore robust, as well as nsenstve to the fluctuatons n the ncong data. The elevaton and reducton of the ebershp values to 1 and 0, respectvely, results n contrast enhanceent n the observablty of the ncong data. Ths helps n focusng on the abguous boundary regon; thereby ganng n ters of the qualty of segentaton. To further prove the perforance of segentaton, MKFCM that lnearly cobnes three kernels,.e., the frst two kernels are the kernels for ntenstes and the local spatal nforaton. To su up, the ert of MKFCM-based age-segentaton algorths s the flexblty n selectons and cobnatons of the kernel functons n dfferent shapes and for dfferent peces of nforaton. After cobnng the dfferent kernels n the kernel space, there s no need to change the coputaton procedures of MFKCM. Ths s another advantage to reflect and fuse the age nforaton fro ultple heterogeneous or hoogeneous sources. MKFCMbased age-segentaton algorths are nherently 4

5 better than other KFCM-based age segentaton ethods. We can deonstrate the MKFCM s sgnfcant flexblty n kernel selectons and cobnatons and the great potental of ths flexblty could brng to age segentaton probles. In the MKFCM fraework, we can easly fuse the texture nforaton nto segentaton algorths by just addng a kernel desgned for the texture nforaton n the coposte kernel. As n the satellte agesegentaton and two-texture age-segentaton probles, sply addng a Gaussan kernel functon of the texture descrptor n the coposte kernel of MKFCM leads to better segentaton results. 3. Proposed Algorth The FCM clusterng algorth was frst proposed by Dunn et. al. [1] and prooted as the general fuzzy c-eans clusterng algorth by Bezdek et. al. [13]. The an purpose of FCM algorth s to ake the vector space of a saple pont be dvded nto a nuber of sub-spaces n accordance wth dstance easure [13]. However, FCM algorth fals to deal wth sgnfcant propertes of ages, snce neghbour pxels are strongly correlated, whch leads to strong nose senstvty. To overcoe ths weakness, Krshnapura and Keller [11] proposed a new clusterng algorth naed PCM. PCM relaxes the colun su constrant of fuzzy ebershp atrx n FCM and ntroduces a possblstc partton atrx, so that possblstc ebershps ay reflect the typcal data ponts to ther clusters. Copared wth FCM, PCM can effectvely elnate the nfluence of nose and outlers on clusterng results. To overcoe the weaknesses of the orgnal PCM algorth cobned the objectve functons of PCM and FCM nto a new objectve functon was presented [18] to provde an proved verson, called PFCM, whch can be nterpreted as PCM and FCM, respectvely, n soe specal cases where soe proper paraeters were adopted. So, PFCM can nhert the erts of both clusterng algorths. The algorth dvdes the data set I = {I1, I. In} nto c clusters and n s the nuber of all the pxels n the age. Let the ebershp functon uk, uk [0, 1] show the degree of the pxel Ik, k=1,... n belongng to cluster (1 c). Then the result can be denoted by a atrx of fuzzy ebershp functon atrx U = [uk]c n. We represent typcalty by tk, tk [0, 1] and the typcalty atrx by T = [tk]c n. Accordng to the defnton of the theory, we have c =1uk = 1 for every pxel n the age. The objectve functon to be nzed s: (11) JMAFCM ( CFuk CT tk ) Ik v (1 tk ) 1 k1 1 k1 where V ={v1,v,..v} s the characterzed ntensty center. The paraeters CF >0, CT >0, >1, γ> 1, the υ > 0 are user defned constants. The constants CF and CT defne the relatve portance of fuzzy ebershp and typcalty values n the objectve functon. Note that uk has the sae eanng of ebershp as that n FCM. Slarly, tk has the sae nterpretaton of typcalty as n PCM. Let, the objectve functon of PFCM can get the nu by updatng the ebershp U, the typcalty T and the cluster centres V as follows: u t v 1/( 1) c D k k j1 Djk k 1 (1) 1 (13) 1/( 1) 1 (( C / ) D ) γ s defned as n k1 n k1 T k ( C u C t ) I F k T k k ( C u C t ) F k T k n uk Dk k1 n uk k1 (14) (15) The ntensty Ik at locaton k far away fro the neghbourhood centre should have less nfluence n the clusterng crteron functon than the locatons close to the neghbourhood centre. 5

6 4. Experental Results Ths research work presents the odfed AFCM based segentaton and for synthetc ages and MR ages. We test and copare the proposed ethod (MAFCM) wth soe other reported algorths on several synthetc ages and synthetc bran MR ages fro two aspects. The perforance of FCM-type algorths depends on the ntalzaton, ths paper does the ntalzaton and teratons depend upon the nput ages and choose the one wth the best objectve functon value. Ths ncreases the relablty of coparson results acqured n the sulatons. The an goals of an age segentaton algorth are optzaton of segentaton accuracy and ts effcency. Consderng accuracy, the proposed ethod s concentrated on obtanng a robust segentaton for nosy ages) and a correct detecton of sall regons. Generally, ncorporatng of spatal nforaton nto the segentaton process wll draatcally ncrease the algorth s coputatonal coplexty. To copare the coputatonal coplexty of the FCM, KFCM, MKFCM and MAFCM segentaton algorths to the Lena age and caeraan age. Each segentaton was and the coputatonal coplexty of each algorth was easured n ters of the average teraton nuber and average runnng te. The test ages lena and caeraan are segented and the results are shown Fg. 1. (c) (d) Fg.1 a) Orgnal lena age b) Orgnal caeraan age c) Segented lena age d) segented caeraan age. Otherwse, the bas feld estaton ay perfor poorly. For ages wth nor nhoogenety, the accuracy of segentaton reles on the global ntensty force. In ths case, we can use relatvely larger, as the weght of global ntensty. Thus, the global ntensty reduces the sclassfcaton for the pxels around the edges. The odfed AFCM has been appled to segent the ages shown n Fg.. In ths paper, the paraeter α s a constant, whch controls the nfluence of the global ntensty force and local ntensty force. When the ntensty nhoogenety s severe, the bas estaton reles on the local ntensty force. In such case, we should choose sall α, as the weght of the global ntensty force. (a) (b) (c) (d) (a) (b) Fg. (a) and (c) Orgnal MR ages (b) and (d) segented ages 6

7 Te consupton No. of teratons Internatonal Journal of Engneerng Research & Technology (IJERT) The quanttatve coparson of the accuracy of those segentaton results was gven n Table 1. It reveals that our MAFCM algorths acheve not only the hghest accuracy n all three cases, but also the best robustness to nose. Ths experent deonstrates agan that the proposed algorth has a better ablty to resst the nfluence of nose. Table1. No. of teratons and te coplexty of the proposed algorth sze. The test ages are generated by addng zeroean Gaussan nose wth dfferent STD to the synthetc age. Coparson between the proposed algorth wth other FCM algorths based on nuber of teratons as shown n Fg 3 and also based on te requred for segentaton as shown n Fg 4. It reveals that the accuracy of the algorth decreases wth the ncrease of the level of nose for all sze of age patches. Iage Intal Cluster Centre Value Fnal Cluster Centre Value No. of Iteratons Te Consupton (sec) Lena Caeraan MRI FCM KFCM MKFCM MAFCM MRI The sze of age patches s an portant paraeter n our MAFCM algorth. It deternes how uch spatal nforaton wll be used, and hence represents a trade-off between the age nforaton and the spatal soothness constrant. Table. Coparson between the proposed algorth wth other FCM algorths Cluster value Fg. 3 Coparson based on nuber of teratons FCM KFCM MKFCM MAFCM Algorth Fnal Cluster Centre Value No. of Iteratons Te Consupton (sec) 0 10 FCM KFCM MKFCM Proposed Table shows the segentaton accuracy of the MAFCM algorth wth age patches of dfferent No. of Iteratons Fg. 4 Te consupton of varous schees based on nuber of teratons Generally, ncorporatng of spatal nforaton nto the segentaton process wll draatcally ncrease the algorth s coputatonal coplexty. To copare the coputatonal coplexty of the FCM, 7

8 KFCM, MKFCM and our MAFCM algorths, we appled each of these four segentaton algorths to the Lena age. Each segentaton was perfored 0 tes, and the coputatonal coplexty of each algorth was easured n ters of the average teraton nuber and average runnng te. 5. Concluson A odfed adaptve fuzzy c-eans clusterng algorth s presented for fuzzy segentaton of MR ages that have been corrupted by ntensty nhoogenetes and nose. We propose an adaptve ethod to copute the weghts for the neghbourhood of each pxel n the age. The proposed adaptve ethod can not only overcoe the effect of the nose effectvely, but also prevent the edge fro blurrng. To address ntensty nhoogenety, the proposed algorth ntroduces the global ntensty nto the algorth and cobnes the local and global ntensty nforaton nto account to ensure the soothness of the derved optal bas feld and prove the accuracy of the segentatons. The proposed odel can segent a bran MR age n 9-10 teratons wthn 0 seconds. Wth good ntalzaton, the odel ay need less teraton and can obtan results n less te. A varety of ages, ncludng synthetc ages, synthetc bran MR ages and real bran MR ages are used to copare the perforance of the proposed algorth. References [1] Ho BC. MRI bran volue abnoraltes n young, nonpsychotc relatves of schzophrena probands are assocated wth subsequent prodroal syptos, Schzophrena Research 007; 96(1):1 13.[] Skka K, Snha N, Sngh PK, Mshra AK, A fully autoated algorth under odfed FCM fraework for proved bran MR age segentaton, Magnetc Resonance Iagng 009;7(7): [3] Awate S, Tasdzen T, Foster N, Whtaker R, Adaptve Markov odelng for utual-nforaton-based, unsupervsed MRI bran-tssue classfcaton, Medcal Iage Analyss 007;10(5): [4] Wong W, Chung A, Bayesan age segentaton usng local sontensty structural orentaton, IEEE Transactons on Iage Processng 005; 14(10): [5] L.A. Zadeh, Fuzzy sets, Inforaton and Control 8 (1965) [6] J.C. Dunn, A fuzzy relatve of the ISODATA process and ts use n detectng copact well separated cluster, Journal of Cybeet 3 (1974) [7] J.C. Bezdek, Pattern Recognton wth Fuzzy Objectve Functon Algorths, Kluwer Acadec Publshers, Norwell, MA, USA, [8] J.C. Bezdek, L.O. Hall, L.P. Clarke, Revew of MR age segentaton technques usng pattern recognton, Medcal Physcs 0 (4) (1993) [9] Xng, Y., Ou, Y., Englander, S., Schnall, M., & Shen, D. (007). Sultaneous estaton and segentaton of T1 ap for breast parenchya easureent, In Fourth IEEE nternatonal syposu on boedcal agng (pp ). [10] Clark, M. C., Hall, L. O., Goldgof, D. B., Velthuzen, R., Murtagh, F. R., & Slbger, M. S.(1998), Autoatc tuor segentaton usng knowledge-based technques, IEEE Transactons on Medcal Iagng, 117, [11] Krshnapura R, Keller JM, The possblstc c-eans algorth: nsghts and recoendatons, IEEE Transactons on Fuzzy Systes 1996; 4(3): [1] Dunn JC, A fuzzy relatve of the ISODATA process and ts use n detectng copact well separated cluster, Journal of Cybernet 1974; 3(3):3 57. [13] Bezdek JC, Pattern recognton wth fuzzy objectve functon algorths, Norwell,MA, USA: Kluwer Acadec Publshers; [14] Bezdek JC, Hall LO, Clarke LP, Revew of MR age segentaton technques usng pattern recognton, Journal of Cybernet 1999; 0(4): [15] Chen, W., Gger, M. L., & Bck, U. (006), A fuzzy c- eans (FCM)-based approach for coputerzed segentaton of breast lesons n dynac contrast-enhanced MR Iages,. Acadec Radolory, 13(1), [16] Ketsetzs, G., & Brady, M. (004), Autoatc segentaton of T1 paraetrc aps of breast MR ages va a hdden Markov rando feld, In Proceedngs of edcal age understandng and analyss. [17] K.S. Chuang, H.L. Tzeng, S.W. Chen, J. Wu, T.J. Chen, Fuzzy c-eans clusterng wth spatal nforaton for age segentaton, Coputerzed Medcal Iagng and Graphcs 30 (1) (006) [18] Pal NR, Pal K, Keller JM, Bezdek JC, A possblstc fuzzy c-eans clusterng algorth, IEEE Transactons on Fuzzy Systes 005;13(4):