Data. ModuLeaf Mini Multileaf Collimator Precision Beam Shaping for Advanced Radiotherapy

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1 Data ModuLeaf Mini Multileaf Collimator Precision Beam Shaping for Advanced Radiotherapy

2 ModuLeaf Mini Multileaf Collimator Precision Beam Shaping for Advanced Radiotherapy The ModuLeaf Mini Multileaf Collimator (mmlc) generates precise and fine field shapes for state-ofthe-art stereotactic radiation treatments of brain and head and neck tumors, as well as other brain lesions such as arteriovenous malformations. The ModuLeaf mmlc s field size and precision also permit it to be used for extra-cranial 3D conformal and Intensity-Modulated Radiation Therapy (IMRT) treatments. The ModuLeaf mmlc provides unique advantages to radiation therapy departments. With a 2.5 width at the isocenter for all 80 leaves and a maximum field size 1 of 10 cm x 12 cm, ModuLeaf is one of the finest resolution mini MLCs available in the industry today Compatibility with most major linear accelerators and treatment planning systems makes it an economical and easy upgrade on current equipment Sophisticated and cutting-edge design developed in close cooperation with the German Cancer Research Center (DKFZ Heidelberg) to ensure ease of use and solid reliability in the clinical routine Demountable design provides clinical flexibility Features and Clinical Benefits In less than five minutes, the ModuLeaf mmlc is easily mounted onto the linear accelerator accessory holder with a motorized trolley. With this quick step, a Siemens linear accelerator becomes a highly accurate treatment delivery machine that performs similar to dedicated radiosurgery systems. When mounted on a Siemens linear accelerator equipped with a 550 TxT Treatment Table, the ModuLeaf mmlc combines its 2.5 leaf projection with exceptional isocentric specifications and provides a sharp tool to irradiate the tumor while sparing the healthy surrounding tissues. The ModuLeaf is a versatile add-on mmlc for 3D conformal IMRT and stereotactic applications. The ModuLeaf mmlc also supports high-resolution IMRT delivery. Its large over-travel and outstanding 0.5 leaf positioning accuracy ensure that the dose distribution effectively delivered to a patient matches the planned dose distribution. Extremely low leakage minimizes unnecessary dose to healthy tissue. A field size of 10 cm x 12 cm enables the ModuLeaf mmlc to be used in a wide variety of anatomical sites. 80 leaves 2.5 leaf width at isocenter when mounted on a Siemens linear accelerator 10 cm x 12 cm maximum field size at isocenter Low interleaf leakage Fast mounting process Note: all specifications at isocenter vary with the actual sourceto-collimator distance. 1. When mounted on a Siemens linear accelerator.

3 ModuLeaf Mini Multileaf Collimator Treatment Applications The ModuLeaf mmlc is a versatile and powerful tool that delivers a precise radiation dose to the target volume while sparing critical tissue. The design allows it to be used in a wide array of clinically valuable treatment applications offering a high precision treatment to a larger patient population. 3D Conformal High leaf resolution and precise leaf positioning enable the user to create more conformal shapes over a range of possible field sizes. In combination with minimal leakage, it provides a superior technique for conformal radiation therapy. IMRT The ModuLeaf mmlc was designed for IMRT. The extensive over-center travel of the leaves, fast positioning of a shape, and low leakage make it ideal for unique field shapes required by IMRT. The ModuLeaf mmlc mounts on the accessory holder of a Siemens linear accelerator. Stereotactic The fine leaf width and accurate leaf positioning allow precise beam shaping for small intracranial and extracranial target volumes, where highest precision is required. The ModuLeaf mmlc is ideal for stereotactic radiotherapy and stereotactic radiosurgery applications. Dose distribution achieved with IMRT, using the ModuLeaf mmlc = Creating an intensity-modulated beam with a series of irregular fields.

4 System Specifications MLC Unit Number of Leaves 80 Leaf Positioning Speed 2 20 /sec at isocenter Leaf Material Tungsten Leaf Over-center Travel 1 55 at isocenter Leaf Height 7 cm Positioning Accuracy 0.5 Max Field Size 1,2 10 cm x 12 cm at isocenter Housing Material Carbon Fiber Leaf Width 1,2 2.5 at isocenter 1. All specifications at isocenter vary with the actual source-to-collimator distance. Details are specified in the isocentric geometric specifications. 2. When the ModuLeaf mmlc is mounted on a Siemens linear accelerator. Weight kg Length Width Height Dimensions Focusing Characteristics of Leaves The ModuLeaf mmlc employs single-focused leaves. The cross section perpendicular to leaf travel direction is focused (i.e., the leaf side surfaces follow the beam divergence). To reduce leakage between leaves (interleaf leakage), the leaves are slightly de-focused (i.e., the leaf side surfaces are focused toward a virtual source offset by a few millimeters from the X-ray source). The leaf ends are rounded to achieve a position-independent penumbra over the entire travel range. Isocentric Geometric Specifications Linear Accelerator Maximum Field Size X Maximum Field Size Y Maximum Overtravel Leaf Width Positioning Accuracy Siemens (All Models) Varian Clinac 1 with MLC Varian Clinac without MLC Clinac 600C, 1800C, 2100C Adaptation Plates Linear Accelerator Manufacturer Linear Accelerator Model Leaf Travel Direction (IEC 61217) Weight kg Siemens All Models X 1.7 Varian All Models except 6/100 X 4.6

5 ModuLeaf Mini Multileaf Collimator Isocenter Clearance Siemens Linear Accelerators Varian Linear Accelerators without MLC 30 cm 35 cm The clearance between the MLC and the isocenter depends on the linear accelerator and its accessory holder. The clearance is between 30 and 35 cm. Data for specific linear accelerators available upon request. mmlc Trolley Dimensions Weight kg Length Width Height ~ In less than five minutes, the ModuLeaf mmlc is mounted and ready for use. Dosimetric Specifications and Measurements Transmission Through Leaves (intraleaf) % Transmission Between Leaves (interleaf) % 80/20% Penumbra (5 cm x 5 cm field) Specification <2 <2.5 <4 Typical Value <2 ~3 1. Measurements were performed on a PRIMUS Linear Accelerator from Siemens at 6 MV, reference: Hartmann, G. and Föhlisch, F. Dosimetric characterization of a new miniature multileaf collimator. Phys. Med. Biol. 47: N , leaf width at isocenter for all 80 leaves provides a maximum field size of 10 cm x 12 cm.

6 Interfaces to Linear Accelerators The ModuLeaf mmlc is compatible with most coercially available linear accelerators. Depending on the linear accelerator model and V&R system, there are different levels of integration available. The usage of Basic Modes have no limitations on linear accelerator models, but requires more interaction from the user during a treatment session. The Automatic and Synchronized Modes have been developed for IMRT treatments. This feature allows verification of treatment setup between ModuLeaf mmlc and the linear accelerator, as well as the execution and verification of step and shoot IMRT treatments. Siemens Linear Accelerators (All Models) Supported R&V Supported Treatment Mode Requirements Treatment Plan Export To Supported File Formats (Basic Mode) Supported File Formats (Automatic Mode and Synchronized Mode) LANTIS 5.2 or above Basic and Automatic Step and Shoot DMIP 6 or 9, SIMTEC -AFS PRIMEVIEW 1.5 or higher, Control Console software version 6.5/7.2 or higher ModuLeaf RTPLink DICOM RT RTPLink DICOM RT (with release 2.3) Sophisticated and cutting-edge, designed in cooperation with the German Cancer Research Center (DKFZ) in Heidelberg, Germany.

7 ModuLeaf Mini Multileaf Collimator ModuLeaf Controller Specifications Controller Workstation Power Supply Computer PC with integrated real time computer Mains Voltage 115/230 V~ Processor 32 bit CPU (Intel PIII, 1.6 G Hz or more) Supply Current 6 A/3 A Network Card 10 baset 10/100 Mbit Primary Fuses 6 AT/3.15 AT Network Protocol TCP/IP Secondary Fuses 3 AT Network Cable BNC, RJ 45 Supply Frequency 50/60 Hz Screen Resolution Min x 1024 pixels Monitor 1.5 A Trolley Charger 0.5 A MLC Controller Workstation Dimensions Weight kg Length Width Height ~ Environmental Conditions The ModuLeaf mmlc may be stored for a maximum period of 10 weeks. Transportation and Storage Ambient Temperature Range Relative Humidity Atmospheric Pressure -10 C to +40 C (14 F to 104 F) 10% to 75% 500 hpa to 1060 hpa Operation +10 C to +40 C 30% to 75% 700 hpa to 1060 hpa Mounted on a Siemens linear accelerator, the ModuLeaf mmlc provides a 30 cm isocenter clearance.

8 On account of certain regional limitations of sales rights and service availability, we cannot guarantee that all products included in this brochure are available through the Siemens sales organization worldwide. Availability and packaging may vary by country and are subject to change without prior notice. Some/All of the features and products described herein may not be available in the United States. The information in this document contains general technical descriptions of specifications and options, as well as standard and optional features which do not always have to be present in individual cases. Siemens reserves the right to modify the design, packaging, specifications, and options described herein without prior notice. Please contact your local Siemens sales representative for the most current information. Note: Any technical data contained in this document may vary within defined tolerances. Original images always lose a certain amount of detail when reproduced. ModuLeaf, 550 TxT, PRIMEVIEW, SIMTEC, PRIMUS, and LANTIS are trademarks of Siemens AG. Siemens Medical Solutions USA, Inc. Oncology Care Systems 4040 Nelson Avenue Concord, California USA Headquarters Siemens Medical Solutions USA 51 Valley Stream Parkway Malvern, PA USA Tel.: Contact Addresses Germany Siemens Medical Solutions Oncology Care Systems - Heidelberg Hans-Bunte-Str. 10 D Heidelberg Germany Contact Address Siemens Medical Solutions USA, Inc. Oncology Care Systems 4040 Nelson Avenue Concord, California USA Tel.: (US and Canada) , Siemens AG Order No. A91004-M2690-G A00 Printed in USA OCS-059 VH KL CL 1.5M