Contact Lens Op-cal Design Op-miza-on U-lizing a Binocular Vision Model. Ben Wooley Johnson & Johnson Vision Care, Inc.

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1 Lens Op-cal Op-miza-on U-lizing a Binocular Vision Model Ben Wooley Johnson & Johnson Vision Care, Inc. March 4, 2016

2 Outline Full Eye and Vision Model > Predicts binocular vision for given viewing distance and brightness level, considering viewing condi-ons, tear film, contact lens, proper-es of eye, and neural/cogni-ve aspects. Level 1 Binocular Vision Model > Binocular VA predic-on from proper-es of re-nal image Level 2 Binocular Vision Model > For presbyopic design need binocular vision predic-on balancing different viewing condi-ons (distances & brightness levels). > This is used in op-mizer. 2 Stage Presbyopic design op-mizer > Determine op-cal wavefront of lens+eye combina-on that give overall best subjec-ve vision. > Determine contact lens designs for specified eye or eyes using full system model.

3 Full Eye and Vision Model OD Scene Eye Binocular Perception (Cognitive) Eye Viewing Distance Luminance L OS Interrelated Models TearThickness(x,y,t) Lens Geometry(x,y,z) Lens Material(x,y,z) Lens Wrapping Wavefront W lens( x,y) 1. Physical 2. Cornea + Wavefront Aberrations W eye function of Rx/ age: 1. Aberrations 2. Pupil Size P(L) 3. Eye Length 4. Accommodation PSF(W) MTF(PSF) NCSF(ν, Illuminance(L,P)) VA monocular VA binocular BV subjective JND subjective PSF Point spread function MTF Modulation transfer function NCSF contrast sensitivity function L Luminance P Pupil Size Rx refractive sphere power W optical wavefront VA visual acuity BV binocular vision JND Just noticeable difference

4 Objec-ve Binocular Vision Model Scene OD OS Wavefront W(x,y) Eye W(r,φ) Wavefront W(x,y) Eye W(r,φ) MTF O S MTF O D Binocular Vision Model NCSF NCSF Binocular Perception BV obj (Cognitive) ective BV LEVEL1 = f 1 ( MTF OD, MTF OS,NCSF) MTF= f 2 ( W OD/OS+lens (x,y)) BV LEVEL1 = f 3 ( W OD, W OS,NCSF) Developed with data from multiple studies (internal) + literature Exact functional form informed by Curtis & Rule (1978) vectorial model Update with new data MTF Modulation transfer function NCSF contrast sensitivity function W optical wavefront BV binocular vision

5 Subjec-ve Binocular Vision Model BV LEVEL2 = Distance Luminance w D,L [ BV LEVEL1 [ W OD (D,L), W os (D,L),NCSF(L)] BV target D,L ] 2 Provides measure of overall binocular performance weigh-ng various viewing condi-ons. Developed from clinical success data and market feedback 100% 95% 90% 85% 80% 75% 70% 65% 60% 55% 50% 45% 40% 35% 30% 25% 20% 15% 10% 5% Pr(Success) ADD (D) 0% OA OA+ AA AA+ AB AB+ AC AC+ BB BB+ BC BC+ w D,L and BV target D,L are key parameters US Patents 8,992,012 and 8,092,012 BV subjec-ve is given in terms of op-cal wavefront of lens+eye combina-on. Does not assume a par-cular eye.

6 Op-miza-on Stage 1 Determine W OD & W OS (lens+eye) > Ini-al fit guide. A, B, C are unique lens+eye W s ADD OD A A A B B B B B OS A A A B B C C C > Ini-al Refrac-on (i.e. -3D) which impacts pupil sizes used in BV objec-ve calcula-on. > Calculate overall Merit Func-on MeritFunction= ADD BV LEVEL2 (ADD) BV LEVEL2 (ADD)= Distance Luminance w D,L [ BV LEVEL [ W OD (D,L,ADD), W os (D,L,ADD),NCSF(L) ] BV target D,L ] 2 > Op-mizer automa-cally varies parameters controlling A, B, and C to minimize MeritFunc-on. > Repeat for all SKUs (sphere refrac-ons) Stage 2 Determine lens design by SKU > Determine lens designs A, B, and C which give targeted subjec-ve vision when combined with desired Eye model.

7 Summary Tear film, contact lens, eye form image on the re-na. Binocular vision models, both objec-ve and subjec-ve, relate vision to proper-es of the re-nal image. This enables an N-lens op-miza-on process that allows a system of lenses (lenses + fit guide) for presbyopes to be op-mized. s first defined in terms of lens+eye wavefronts. Lens designs are then determined to provide target subjec-ve vision for the targeted eye. Ben Wooley Johnson & Johnson Vision Care, Inc. Jacksonville, FL bwooley@its.jnj.com (904) (office) (904) (cell)

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