UNICEF Supply Division How we drive innovation within medical devices
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1 UNICEF Supply Division How we drive innovation within medical devices WHO 3rd Forum On Medical Devices May 2017 Kristoffer Gandrup-Marino Chief, Innovation Unit UNICEF/UN043566/Lister
2 UNICEF how we work Works across 190 countries and territories Works with governments based on country specific agreements to address country specific needs and contexts Works in Programmes, Advocacy, Innovation, Technical Assistance Has an annual budget of approximately USD 5 billion to achieve results for children Supplies are an important component of this budget and are a direct expression of children s rights
3 UNICEF Supply UNICEF Supply Division is UNICEF s supply & logistics headquarters located in Copenhagen, Denmark UNICEF s Supply Community of 1023 supply and logistics staff serve children in 94 countries Largest humanitarian warehouse in the world. Other UNICEF warehouse hubs are located in Dubai, Shanghai, Panama, and Djibouti Serves as a centre of expertise and knowledge on essential supplies for children and supply chains and build capacities of national governments Helps meet UNICEF s Core Commitments for Children in emergencies by providing rapid response to emergency supply and logistics needs Provides procurement services to governments and development partners on strategic-essential supplies Contributes to influencing markets to ensure sustainable access to essentials supplies for children Uses product innovation to increase results and decrease costs
4 UNICEF expenditure (2015, by major material groups) 2015: $3.428 billion of supplies and services 2015: $1.755 billion in procurement on behalf of 102 governments and partners 2016: $3.519 billion of supplies and services 100% Vaccines $1.725 billion Gavi, BMGF, WHO, PAHO MSF, CDC 100% Pharmaceuticals $151.4 million WHO, UNFPA, UNDP, GFATM UNITAID, CHAI, MSF 100% Nutrition $150.6 million WHO, WFP,, MSF, CIFF 95% Medical supplies $110.4 million WHO, UNFPA, UNDP, GFATM UNITAID, CHAI, MSF, CDC 100% International freight $104.3 million UNDP, UNHCR, UNOPS, WHO ~30% Construction $102.3 million SAVE, WB 30% Water & sanitation $96.4 million WHO, Oxfam, SAVE, UNHCR 100% Cold chain $75.6 million Gavi, BMGF, WHO, PAHO 30% Education $66.1 million SAVE, WB 100% Bed nets & insect. $58.7 million WHO, UNFPA, UNDP, GFATM UNITAID 85% of UNICEF procurement is in collaboration with other UN agencies ($2.9b) 90% with UN agencies and other development partners ($3.1b)
5 Find out what we buy and how we buy Resources: UNICEF Supply Catalogue (over 2000 commodities) Technical Standards (e.g, on medical devices) 71 Market Notes (published ) Procurement Policies United Nations Global Marketplace (UNGM) Go to : For suppliers and Service providers
6 Product Innovation Ecosystem Need Development Scale In depth analysis of full context and communication of need User research Program Inputs from field offices Feedback from partners Expression of Interest (EOI), Request for Proposals (RFPs) Development of Target Product Profiles (TPPs) for articulating needs to industry Industry-Stakeholder consultations to align on opportunities and challenges Product Development & Testing Industry: Product Development Regulatory/clinical approvals UNICEF: Working non-exclusively with developers Continuous monitoring of R&D landscape and consultations with industry Field trials to validate impact in UNICEF s settings Supporting initial uptake through volume guarantees and influencing markets activities Advance Purchase Commitments (APCs) Technical Guidance Advocacy with Country Offices, implementing partners and key stakeholders Addressing other market goals through procurement tactics
7 Product Innovation Projects Pipeline
8 Crossing the Chasm How we increase perceived value * Market pull Tipping Point Sustainable Market Field Trials (FT) Programmatic and technical guidance Engagements with partners, such as WHO Advocacy to end-users and implementing partners How we reduce cost Foster competition Drive voloume Strategic/transparent procurement *Supply Financing Mechanism
9 Acute Respiratory Infection Diagnostic Aid (ARIDA) Problem: Pneumonia accounts for 16% of all deaths of children under 5 years old, killing children in Many children die because the symptoms of pneumonia are not recognized. Outcome: An automated device that helps healthcare workers at the community level diagnose pneumonia. Status: The first ARIDA device has been manufactured and field trials in Ethiopia are ongoing. UNICEF/Nepal/Hayalanesh/2016
10 ZIKA R&D: Diagnostics & Vaccines Problem: Lack of critical products for combating the Zika epidemic. There is currently no Zika vaccine available and >95% of Zika diagnosis are clinical with lead-time for lab diagnosis 4-8 weeks, if/when lab available. Outcome: Development of a Zika vaccine and sensitive and specific Zika (POC) diagnostic. Status: Creation of TPPs jointly with partners (WHO & PAHO) to communicate the desired performance of Zika products Industry Consultation held th May, 2016 Initial forecast developed based on WHO classification of ZIKV transmission, environmental suitability for vector-borne transmission, potential target cohorts and various uptake scenarios. Secured USAID funding (USD 10 million), enabling UNICEF to employ an APC covering to reduce demand uncertainty for developers who have invested in R&D of ZIKV POC diagnostics. Availability of POC diagnostics and controlled accuracy trials to be conducted Continuous monitoring of the vaccine and diagnostic R&D landscape and consultations with industry.
11 Oxygen System Technologies Problem: Inherent complexities in oxygen system planning, supply, installation and maintenance of oxygen systems at all levels of the healthcare system. Outcome: Exploring publishing of joint UNICEF-WHO technical specifications and guidance UNICEF Supply Catalogue updated with more appropriate oxygen system products Convening with stakeholders on oxygen system strategies for an aligned and holistic approach to oxygen system guidance, planning, procurement and development of appropriate technologies. Status: Consultation and alignment with key stakeholders.
12 Product Innovation Challenges Need Development Scale Prioritization of R&D needs Working through the tradeoffs to create a TPP that matches needs Partnering with normative agents, technical and procurement partners Designing pull mechanisms that appropriately balances risks Sufficient funding raised for meaningful pull Ensuring product use Measuring impact in programme countries and in markets Problem of the counterfactuals
13 UNICEF/SUDA2014-XX228/Noorani Thank You Kristoffer Gandrup-Marino
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