PhenX Toolkit Homepage

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1 PhenX Toolkit Homepage q Browse Protocols by selecting Protocols from the site navigation menu at top of homepage OR by selecting PhenX Protocols button q Browse Domains by selecting Research Domains button q Access Collections by selecting one of the collection buttons at the bottom q Search the Toolkit option (using keywords) is on every page

2 PhenX Definitions DOMAIN: A topic area with a unifying theme Environmental Exposures MEASURE: A certain characteristic of, or related to, a study subject Air Contaminants in the Home Environment PROTOCOL: Standard procedure recommended by a Working Group to collect and record a PhenX measure Relationships of Indoor, Outdoor and Personal Air (RIOPA) Study Activity Questionnaire SUPPLEMENTAL INFORMATION: Includes other protocols considered by the Working Group (not selected for the Toolkit) Lifetime Farm Exposure

3 More Definitions ESSENTIAL PROTOCOLS: other PhenX Toolkit protocols that are needed to interpret the results of the protocols of interest, such as age when measuring height or weight. RELATED PROTOCOLS: An additional PhenX protocols that the user may find helpful based on the selection of a particular PhenX protocol. Related PhenX protocols can include additional protocols that are needed to calculate a Derived Variable (e.g., Weight and Height are needed to calculate BMI), protocols that are commonly used in presentations and publications to present the value of the chosen protocol (e.g., Height and Weight by Race and Ethnicity), protocols that are conceptually related to the chosen protocol (e.g., Current Educational Attainment is conceptually related to Annual Family Income and Arm Span is conceptually related to Height), protocols that are physiologically and/or biologically related to the chosen protocol (e.g., Stroke and Heart Disease). Related PhenX Protocols are suggestions only. Additional definitions available in Glossary and Acronyms

4 Browse protocols using filters No filters selected All protocols are listed One filter selected and identified at top of list Only protocols that fulfill criteria are listed

5 Browsing protocols: selecting filters from multiple categories No filters selected Bioassay selected from Data Collection Mode Bioassay selected from Data Collection Mode and Infant selected from LifeStage All 730 protocols will be listed 57 protocols that use Bioassays will be listed 16 protocols that use Bioassays and pertain to Infants will be listed In the example above, once Bioassay is selected from the Data Collection Mode category, the number of protocols in the Lifestage categories gets restricted so that only Bioassay protocols are available to browse. Similarly, once Infant is selected from the LifeStage category, only Protocols for Bioassays AND Infants will display.

6 Browsing protocols: selecting filters from same category No filters selected Bioassay selected from Data Collection Mode Bioassay and Clinical Examination selected from Data Collection Mode All 730 protocols will be listed 57 protocols that use Bioassays will be listed 108 protocols that use Bioassays OR Clinical Examination Data Collection Modes will be listed

7 Using Advanced Search to find Protocols: Smart Search vs Text Search Step 1: Enter a single search term, for example, arthritis Step 2: Choose Smart Search OR Text Search Step 3: Comparison of query results Smart Search returns 13 protocols Text Search returns 25 protocols

8 Using Advanced Search to find Protocols: How to use quotes (with Smart Search) Searching for current age with quotation marks will take you directly to the Protocol called, Current Age, when Smart Search is used. With quotations marks Searching for current age without quotation marks will return the Protocol called Current Age, plus over 120 other records, when Smart Search is used. Without quotations marks

9 Select Measure to access relevant Research Domain Information Protocols and Measures Research Domain Information button is available under the Measure Sample Research Domain Page

10 Saving Protocols to My Toolkit From the search results: 1. Click checkboxes next to desired protocols 2. Select Add Selected to Toolkit button From the protocol page: 3. Select Add to My Toolkit button Protocols are available for download in up to 3 different languages and in multiple formats

11 While Essential Protocols are not required to be added to My Toolkit, they are critical to the collection of a selected Protocol or are necessary for the interpretation of results Add Essential Protocols via the link in the notification or from the dropdown menu The notification goes away after user has selected all Essential Protocols

12 All measurement protocols can be downloaded as a report and PDF. A report will contain details of the protocol such specific instructions and description of the protocol. It will also contain toolkit guidance information. Three additional resources are available. A Data Collection Worksheet (DCW) is a prototype data collection tool (in MS Word) for the PhenX protocol. It identifies and captures each data item required and collected by the protocol. A Data Dictionary (DD) lists each variable included in the protocol DCW and its attributes. Data dictionaries are available in two formats: 1) the Word format captures skip patterns commonly used in Epidemiology studies; 2) the CSV format is compatible with the database of Genotypes and Phenotypes (dbgap) data submission packet. REDCap instruments for each protocol are available for download.

13 Questions and Comments PhenX Frequently Asked Questions (FAQs) under Help PhenX Feedback (bottom of every page)

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