Register your instrument! VisioNize box. Operating manual

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1 N) manual Register your instrument! Operating manual

2 Copyright 2017 Eppendorf AG, Germany. All rights reserved, including graphics and images. No part of this publication may be reproduced without the prior permission of the copyright owner. Eppendorf and the Eppendorf Brand Design are registered trademarks of Eppendorf AG, Germany. Registered trademarks and protected trademarks are not marked in all cases with or in this manual /

3 Table of contents 3 Table of contents 1 Operating instructions Using this manual Danger symbols and danger levels Danger symbols Danger levels Symbols used Safety Intended use User profile Warnings for intended use Information on product liability Product description Delivery package Product overview LED status display Name plate Prerequisites for the installation Installing the Anschlussschema Compatible devices Connecting the centrifuge 5424 R Connecting the Innova 44 and Innova 42 families Connecting freezers Connecting the Mastercycler nexus and the BioSpectrometer family Configuration Login Entering general data Configuring the network Adding a new device Deselecting the device Software Updating the software automatically Using the web interface to update the software Troubleshooting Error messages

4 4 Table of contents 9 Maintenance Cleaning Technical data Power supply Mains/power adapter USB port Weight/dimensions Ambient conditions Ordering information Transport, storage and disposal Decontamination before shipment Disposal Certificates

5 Operating instructions 5 1 Operating instructions 1.1 Using this manual Read this operating manual completely before using the device for the first time. Also observe the instructions for use of the accessories. This operating manual is part of the product. Thus, it must always be easily accessible. Enclose this operating manual when transferring the device to third parties. You will find the current version of the operating manual for all available languages on our website under Danger symbols and danger levels Danger symbols The safety instructions in this manual have the following danger symbols and danger levels: Hazard point Material damage Danger levels DANGER WARNING CAUTION NOTICE Will lead to severe injuries or death. May lead to severe injuries or death. May lead to light to moderate injuries. May lead to material damage. 1.3 Symbols used Depiction Meaning 1. Actions in the specified order 2. Actions without a specified order List: Text Display or software texts Additional information

6 6 Safety 2 Safety 2.1 Intended use The device is intended to be used as an external accessory that acts as a connector between lab instruments and the VisioNize platform to convert data provided by the lab instrument in the VisioNize communication protocol and forward the data to the VisioNize platform for further processing. The device is intended for research use only. 2.2 User profile The device and accessories may only be operated by trained and skilled personnel. Before using the device, read the operating manual carefully and familiarize yourself with the device's mode of operation. 2.3 Warnings for intended use CAUTION! Poor safety due to incorrect accessories and spare parts. The use of accessories and spare parts other than those recommended by Eppendorf may impair the safety, functioning and precision of the device. Eppendorf cannot be held liable or accept any liability for damage resulting from the use of incorrect or non-recommended accessories and spare parts, or from the improper use of such equipment. Only use accessories and original spare parts recommended by Eppendorf. NOTICE! Damage from overheating. Do not install the device near heat sources (e.g. heating, drying cabinet). Do not expose the device to direct sunlight. Ensure unobstructed air circulation. NOTICE! Damage to the device due to unauthorized modifications. Do not open the device. Do not carry out any work inside the device. When connected to other devices, the sum of the noise emissions may exceed the defined thresholds of the corresponding standards.

7 Safety 7 To prevent unauthorized access, data loss, sample loss and data misuse, secure the against undesired access from the Internet. Contact your network administrator. The safety notes and other notes in the operating manual of the connected devices apply in addition to the warning notes and hints in this manual. Read the operating manual of the connected lab devices before using the for the first time. 2.4 Information on product liability In the following cases, the designated protection of the device may be compromised. Liability for any resulting property damage or personal injury is then transferred to the operator: The device is not used in accordance with the operating manual. The device is used outside of its intended use. The device is used with accessories or consumables which are not recommended by Eppendorf. The device is maintained or repaired by people not authorized by Eppendorf. The user makes unauthorized changes to the device.

8 8 Product description 3 Product description 3.1 Delivery package Quantity 3.2 Product overview Description 1 1 Mains/power adapter 1 Installation instructions Power LED 2 Status LED 3 Mains/power supply 4 Ethernet interface 5 USB interfaces

9 Product description LED status display LED left Description Note switched off white blue The is switched off. The starts up. The is ready for operation. yellow The software is being updated. Wait for the left LED to turn blue again. green red The software update is complete. Error flashing red Critical error Restart the. Contact Eppendorf Service if the error persists. LED right Description Note white The starts up. flashing red A new device has been detected For example, connecting and or is no longer detected. removing a lab device. flashing green flashing cyan yellow, flashes once The device data is being updated. A USB stick has been connected or removed. A new software version was found. Data is read from a connected device.

10 10 Product description 3.4 Name plate MAC address 2 Serial number

11 Prerequisites for the installation 11 4 Prerequisites for the installation VisioNize core is installed. There is a power supply connection available near the device which corresponds to the specifications on the mains/power supply device. There is an enabled network socket for access to the local network available near the device. A standard Ethernet cable is available. A suitable connecting cable between the and the lab device is available. The lab device has the required software version. You can find more information on the connecting cable and the software version in the "Compatible devices chapter.

12 12 Installing the 5 Installing the The may only be connected to the local network and commissioned by a network administrator or a qualified person. An incompatible communication structure leads to malfunctions in the lab devices. Connect approved lab devices only. 1. Use the mains/power adapter to connect the to the mains/power line. 2. Connect the and the network socket using a standard Ethernet cable. 3. Use a suitable connecting cable to connect lab devices without a network connection to the.

13 auto vent Centrifuge 5920 R Mastercycler nexus Installing the Anschlussschema a 6b 6c 1 VisioNize-core server 2 VisioNize-core client 3 Router/IT department 4 VisioNize-onboard device 5 6a VisioNize-qualified device 6b VisioNize-qualified device 6c VisioNize-qualified device 7 USB/serial cable 8 USB cable A/B 9 Ethernet cable

14 14 Installing the 5.2 Compatible devices The listed devices exchange data via the if the devices have at least the software version stated below and are connected to the via the associated cables. The integration of older ultra-low temperature freezers in VisioNize requires a service upgrade by the Eppendorf Service. Contact your local Eppendorf partner to arrange the service update. Device type Device Minimum software version Required connection cable Centrifuges Centrifuge 5920 R V Centrifuge 5910 R V Centrifuge 5424 R V Mixers and ThermoMixer C V temperature control ThermoMixer F1.5 V systems ThermoMixer FP V ThermoStat C V Shaker Innova S44 No software update required Innova S43 No software update required Innova S42 No software update required Ultra-low temperature freezers New Brunswick Premium C320 New Brunswick Innova U725 CryoCube F570 V F V5.0.4 V5.0.4 CryoCube F740 V

15 Installing the 15 Device type Device Minimum software version Required connection cable Thermal cycler Mastercycler nexus V Mastercycler nexus V eco Mastercycler nexus V gradient Mastercycler nexus V gradient eco Mastercycler nexus V flat Mastercycler nexus V flat eco Mastercycler nexus V GSX1 Mastercycler nexus V SX1 Mastercycler nexus V GSX1e Mastercycler nexus V SX1e Mastercycler nexus V gradient eco Detection devices BioSpectrometer V basic BioSpectrometer V kinetic BioSpectrometer V fluorescence BioPhotometer D30 V

16 16 Installing the 5.3 Connecting the centrifuge 5424 R 1. Remove the USB cable from the centrifuge. 2. Switch on the centrifuge. 3. Connect the USB cable to the centrifuge. 5.4 Connecting the Innova 44 and Innova 42 families To operate the Innova 44 and the Innova 42 families on the, set the following values for the RS232 interface. Port mode: Slave Baud rate: Connecting freezers The F740 freezer family can be connected to the VisioNize network without any modifications. Other freezers require the service upgrade with the article number as well as spare parts and F before they can be connected to the. 5.6 Connecting the Mastercycler nexus and the BioSpectrometer family To operate the Mastercycler nexus or a BioSpectrometer with the, the following steps are required. 1. Update the software. 2. Activate remote access for the Mastercycler. 3. Integrate the Mastercycler or BioSpectrometer into the local network. If all the devices are allocated to the same subnet, the detects the Mastercycler or the BioSpectrometer. Older BioSpectrometers do not have an Ethernet port.

17 Configuration 17 6 Configuration General data, network parameters and connected lab devices are managed via a web interface. If a PC is connected with the in the same network, a web browser is used to configure the. If using the web interface, the latest versions of the Chrome or Firefox web browsers should be used. 6.1 Login 1. Enter the following address in the Internet browser: "epdevice" + serial number. Example: epdevice1006ab The login window opens. 2. If the login window does not open, enter the IP address of the in the address line. The IP address is available from your network administrator. 3. Enter the password "Eppendorf". The Dashboard with the Selected devices page opens. 6.2 Entering general data 1. Select the Settings menu. The General tab opens and shows the areas General Date & Time Password General 2. To improve the identification of the in the network, enter the device name. 3. To adopt the changes, click on the Save General Settings button. Date & Time The first two lines show the current time of the and the current time of the browser. The current time of the browser corresponds to the current time of the computer on which the browser is running. If the time is not set correctly in the, the VisioNize core software cannot process the data of the connected lab devices correctly. 4. If the does not reach a time server, click on the Save browser time to device button. The then uses the current time of the computer.

18 18 Configuration Password 5. Enter the current and the new password. 6. To adopt the changes, click on the Change password button. Always replace the default password of a new with an individual password. Factory settings 7. To overwrite the settings of the with the factory settings, click on the Reset factory settings button. 6.3 Configuring the network The is set to accept automatic configuration via a DHCP server. Configuring the network manually 1. If the is not configured automatically, select the Settings menu item in the web interface. 2. Select the Network tab. The following areas are displayed: Network settings DNS settings NTP settings 3. Click on the Manual button in all areas. 4. Enter the IP addresses for the network and the DNS. 5. If the specified time server cannot be not reached, enter the Internet address of a time server in the NTP server (URL) line. 6. Press the Save network settings button. 7. Restart the. If the attempt to configure the fails, note down the MAC address at the rear of the and contact an IT specialist in your company.

19 Configuration Adding a new device The only processes data of lab devices that are included in the list of active devices. Newly connected devices are selected automatically by the until the maximum quantity of 4 lab devices has been reached. The web interface is used to manage the lab devices manually. 1. Select the Dashboard menu. 2. Select the Available devices tab. A list of available devices is displayed. 3. To add a device, click on the +Select button. 6.5 Deselecting the device 1. Select the Dashboard menu. 2. Select the Selected devices tab. All active devices are shown. 3. To deselect a device, click on the -Deselect button.

20 20 Software 7 Software 7.1 Updating the software automatically The software is available as a ZIP archive. 1. Unpack the ZIP archive. 2. Copy the unpacked files to an empty USB stick. 3. Connect the device to the mains/power line. Both LEDs light up in white. 4. When the left LED lights up in blue, connect the USB stick to the device. After a short waiting period, the LED lights up in yellow. The update starts automatically. The device is restarted several times. When the left LED lights up in blue again, the update is complete. 5. If the update does not start automatically, use the web interface. 6. Remove the USB stick from the device when the update is complete. 7.2 Using the web interface to update the software The update procedure is started in the Settings menu on the Firmware update tab. The software update is identical to the procedure described above. Prerequisites A USB stick with the firmware is connected to the. 1. Select the Settings menu. On the Firmware update tab the current firmware version in the and the firmware version on the USB stick are displayed. 2. In the Automatic update area, select the Manual button. 3. If the firmware version on the USB stick is more recent, select the Install Firmware button.

21 Troubleshooting 21 8 Troubleshooting 8.1 Error messages Problem Cause Solution Web interface not Various causes. Restart the. found. Various causes. Contact the system administrator. Various causes. Contact your local Eppendorf partner. Lab device is not Lab device is not in the same Link the lab device to the displayed in the web interface. network as the. same network as the. The lab device is not displayed in VisioNize core. Software update does not work automatically. The lab device is not connected correctly. The lab device is not switched on. The lab device is not compatible with the. The software version of the lab device is not compatible with the. Check the cables and plugs between the devices. Switch on the lab device. Only link compatible Eppendorf lab devices (see Compatible devices chapter). Carry out a software update of the lab device. Various causes. Restart the. Various causes. Contact the system administrator. Various causes. Contact your local Eppendorf partner. The software version on the is later or identical to the software version on the USB stick. The software version on the is later or identical to the software version on the USB stick. Download the latest software update for the and install it. To load an older software version onto the VisioNize box use the manual update function in the web interface of the.

22 22 Troubleshooting Problem Cause Solution During the update the left LED changes from yellow to red. The left LED lights up in red. Interrupted communication between the lab device and VisioNize via the VisioNize box. The update process was not completed. The update process was not completed. Download and install the software update for the VisioNize Box again. Use a different USB stick. Various causes. Restart the. Various causes. Perform the software update with the latest version for the. Various causes. Use the Reset factory settings function to restore the factory settings in the web interface. Various causes. Contact your local Eppendorf partner. Various causes. Check the cables and plugs between the individual components. Various causes. Restart the and restart the lab device. Various causes. Perform the software update with the latest version for the. Various causes. Use the Reset factory settings function to restore the factory settings in the web interface. Various causes. Contact the system administrator. Various causes. Contact your local Eppendorf partner.

23 Maintenance 23 9 Maintenance 9.1 Cleaning NOTICE! Damage to the device due to penetration of liquids. Penetrating liquids may damage the device. Switch off the device and disconnect the power plug before starting cleaning or disinfection work. Do not allow any liquid to penetrate the inside of the housing. Do not spray clean or spray disinfect the housing or the control device. Only plug the device back in if it is completely dry, both inside and outside. NOTICE! Damage to device from unsuitable cleaning fluids or sharp or pointed objects. Unsuitable cleaning agents can damage the device. Never use corrosive cleaning agents, aggressive solvents or abrasive polishes. Do not clean the device using sharp objects. 1. Switch off the device. 2. Disconnect the device from the mains/power line. 3. Remove contamination on the outside using a mild cleaning agent or isopropanol (70 %). 4. Remove cleaning agent residues using a damp cloth. 5. Let the device dry. 6. Connect the dry device to the mains/power line and put it into operation.

24 24 Technical data 10 Technical data 10.1 Power supply Mains/power adapter Input voltage 100 V 240 V, ±10 % Frequency 50 Hz 60 Hz, ±5 % Output voltage DC 5 V, ±6 % Maximum output power Power consumption Maximum Standby (at 230 VAC, without load) Overvoltage category USB port 20 W 24 W <0.1 W II Degree of contamination 2 (IEC 664) Protection class II Input voltage DC 5 V, ±6 % Maximum current consumption DC 4 A Power consumption Normal operation without power 4 W load on the USB ports Standby 1.25 W Degree of contamination 2 (IEC 664) Protection class III Power load, maximum per port 225 ma ±25 ma

25 Technical data Weight/dimensions Width Height Depth Weight 105 mm 32 mm 84 mm 475 g 10.3 Ambient conditions Environment: For indoor use only. Ambient temperature: 5 C 40 C Relative humidity: 10 % 95 %, non-condensing humidity Atmospheric pressure: 79.5 kpa 106 kpa Use up to a height of 2000 m above sea level.

26 26 Ordering information 11 Ordering information Order no. Description (International) with mains/power adaptor Mains/power adaptor Cable for Innova 44 and Innova 42 Familie USB to RS232 adapter, 5 m Cable to connect devices with ethernet interface to VisioNize , Ethernet, length 5 m Cable for CryoCube F USB/RS485 adapter, 5 m Adapter for ThemoMixer USB cable type A/B length 3 m Service Upgrade for UTL-Freezer Cable for U725 family, CryoCube F570 family USB/RS485 adapter, 5 m RS-485 interface kit F for Premium/Innova/HEF/CryoCube F570 freezers (except U360)

27 Transport, storage and disposal Transport, storage and disposal 12.1 Decontamination before shipment CAUTION! Use of a contaminated device may result in personal injuries and damage to the device. Clean and decontaminate the device in accordance with the cleaning instructions before shipping or storage. Hazardous substances are: solutions presenting a hazard to health potentially infectious agents organic solvents and reagents radioactive substances proteins presenting a hazard to health DNA 1. Please note the information in the document "Decontamination certificate for product returns". It is available as PDF document on our website 2. Enter the serial number of the device in the decontamination certificate. 3. Enclose the completed decontamination certificate for returned goods with the device. 4. Send the device to Eppendorf AG or an authorized service center.

28 28 Transport, storage and disposal 12.2 Disposal In case the product is to be disposed of, the relevant legal regulations are to be observed. Information on the disposal of electrical and electronic devices in the European Community: Within the European Community, the disposal of electrical devices is regulated by national regulations based on EU Directive 2012/19/EU pertaining to waste electrical and electronic equipment (WEEE). According to these regulations, any devices supplied after August 13, 2005, in the business-to-business sphere, to which this product is assigned, may no longer be disposed of in municipal or domestic waste. To document this, they have been marked with the following identification: Because disposal regulations may differ from one country to another within the EU, please contact your supplier if necessary.

29 Certificates

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