Urine Preservatives Collection and Transportation for 24-Hour Urine Specimens

Transcription

1 Preservatives Collection and Transportation for 24-Hour Specimens The Department of Laboratory Medicine and Pathology at Mayo Clinic initiated a study to determine stability of analytes under different preservative conditions. This reference chart, built from that study, will enable you to select either temperature conditions or preservatives to maximize the number of tests that can be performed on a single 24-hour collection. Note: See the Test Catalog for test-specific collection requirements. Protect from light.* Aldosterone, 24 Hour, Aldosterone with Sodium, 24 Hour, Alpha-1-Microglobulin, 24 Hour, Aluminum, 24 Hour, Ammonium, 24 Hour, Arsenic with Reflex, 24 Hour, Arsenic Fractionation, 24 Hour, Arylsulfatase A, 24 Hour, Cadmium, 24 Hour, 2018 Mayo Foundation for Medical Education and Research ALDU OK OK OK OK Preferred OK No No No No No ALDNA OK OK OK OK Preferred OK No No No No No A1M24 OK Preferred OK OK OK OK No No No OK OK ALU OK Preferred OK No OK OK No OK OK No OK AMMO No OK OK No No Preferred No No No No No ASU24 OK Preferred OK No OK OK No OK No No OK ASFR OK Preferred OK No OK OK No OK No No OK ARSU No Required No No No No No No No No No CDU OK Preferred OK No OK OK No OK OK No OK Calcium, 24 Hour, CALU OK Preferred OK OK OK OK No OK OK OK OK Catecholamine Fractionation, Free, 24 Hour, CATU No OK OK OK Preferred No No OK OK No No Chloride, 24 Hour, CLU OK Preferred OK OK OK OK No No No OK OK Chromium, 24 Hour, CRU OK Preferred OK No No No No No No No OK Page 1 of 5 Ambient with preservative OK 14 days Ambient with preservative OK 7 days 7 days 28 days 72 hours 72 hours 72 hours A Frozen NO 28 days 72 hours Ambient with preservative OK 7 days 14 days 28 days

2 Preservatives Collection and Transportation for 24-Hour Specimens (continued) Citrate Excretion, 24 Hour, CITR No OK OK OK No Preferred No No No OK No Cobalt, 24 Hour, COU OK Preferred OK No OK OK No OK OK No OK Copper, 24 Hour, CUU OK Preferred OK No OK OK No OK OK No No Cortisol/Cortisone, Free, 24 Hour, Cortisol, Free, 24 Hour, Creatinine, 24 Hour, Creatinine Clearance, Serum and 24 Hour Cystinuria Profile, Quantitative, 24 Hour, 2, 3-Dinor-11 Beta-Prostaglandin F2 Alpha, Electrophoresis, Protein, 24 Hour, Electrophoresis, Protein, 24 Hour, INTERNAL ONLY Gadolinium, 24 Hour, COCOU No OK OK Preferred OK OK No No No No No CORTU No OK OK Preferred OK OK No No No No No CTU OK Preferred OK OK OK OK OK OK OK OK Preferred CRCL Preferred OK OK OK OK OK OK OK OK OK Preferred CYSQN No OK OK No No Preferred No No No No No 23BPG No Preferred OK OK OK OK OK No No No No EPU OK Preferred OK No No OK No No No OK OK PEU OK Preferred OK No No OK No No No OK OK GDU OK Preferred OK No No OK No OK OK No OK Glucose, 24 Hour, GLUR No OK OK Preferred OK OK No OK OK OK No Heavy Metals Screen, with Reflex, 24 Hour, Homovanillic (HVA), 24 Hour, 5-Hydroxyindoleacetic (5-HIAA), 24 Hour, HMU24 No Preferred OK No OK OK No OK No No No HVA No No No No Preferred No No OK No No No HIAA No OK OK OK Preferred OK OK OK OK OK No Page 2 of 5 28 days 28 days Ambient with preservative OK 72 hours Ambient with preservative OK 7 days Refrig preferred 30 days 30 days 30 days Refrig preferred Frozen preferred 70 days Refrig 14 days 30 days 8 hours 72 hours 72 hours 28 days 180 days Refrig preferred 56 days 365 days

3 Preservatives Collection and Transportation for 24-Hour Specimens (continued) Immunofixation, 24 Hour, Immunoglobulin Total Light Chains, IFXU OK Preferred OK No No OK No No No OK OK TLCU OK < 72 hours Preferred OK No No No No No No No < 72 hours OK Iodine, 24 Hour, UIOD OK Preferred OK No OK No No No No No OK Lead, 24 Hour, PBU OK Preferred OK No OK OK No OK OK No OK Leukotriene E4, LTE4 No Preferred OK OK OK OK OK No No No OK Magnesium, 24 Hour, Manganese, 24 Hour, MAGU OK Preferred OK OK OK OK No OK OK OK OK MNU OK Preferred OK No No No No No No No OK Mercury, 24 Hour, HGU No Preferred OK No OK OK No OK OK No No Metanephrines, Fractionated, 24 Hour, N-Methylhistamine, 24 Hour, Microalbuminuria, 24 Hour, Monoclonal Protein Study, 24 Hour, METAF No OK OK Preferred Preferred OK OK OK OK No No NMHIN OK Preferred OK OK OK OK OK OK OK No OK MA24 OK Preferred OK OK No OK No No No OK OK MPSU OK Preferred OK No No OK No No No OK OK Nickel, 24 Hour, NIU OK Preferred OK No OK No No No OK No OK Nitrogen, Total, 24 Hour, NITU OK OK Preferred No OK OK OK OK No OK OK Oxalate, 24 Hour, OXU No OK OK No No Preferred No No No OK No Phosphorus, 24 Hour, POU OK Preferred OK OK OK OK No OK OK OK Preferred Page 3 of 5 72 hours 20 days 72 hours Refrig preferred 146 days 146 days 146 days 28 days 30 days 24 hours 72 hours 7 days 7 days Refrig preferred 8 days 24 hours 7 days 72 hours 28 days 7 days 7 days

4 Preservatives Collection and Transportation for 24-Hour Specimens (continued) ph, 24 Hour, UPH24 No OK OK No No Preferred No No No OK No Porphyrins, Quantitative, 24 Hour, Potassium, 24 Hour, Protein, Total, 24 Hour, Retinol-Binding Protein, 24 Hour, Serotonin, 24 Hour, PQNU No No No No No No Required* No No No No KUR OK Preferred OK OK OK OK OK OK OK OK Preferred PTU No Preferred OK OK No OK No No No OK Preferred RBP24 Preferred OK OK OK No OK No No No OK Preferred SERU No Preferred OK No Preferred OK No No OK No OK Sodium, 24 Hour, NAU OK Preferred OK OK OK OK No OK OK OK Preferred Sulfate, 24 Hour, SULFU No Preferred OK OK No OK OK No No OK OK Supersaturation Profile, 24 Hour, Thallium, 24 Hour, SAT24 No OK OK No No Preferred No No No No No TLU OK Preferred OK No OK OK No OK OK No OK Urea, 24 Hour, URAU No OK OK Preferred OK OK OK OK OK OK No Uric, 24 Hour, Vanillylmandelic (VMA), 24 Hour, URCU No OK OK Preferred No OK OK No No OK No VMA No No No OK Preferred No No OK OK No No Zinc, 24 Hour, ZNU OK Preferred OK No OK OK No OK OK No OK Frozen 7 days Refrig NO 7 days 24 hours Frozen preferred 14 days Refrig OK 7 days 7 days 28 days 180 days 28 days Refrig OK Protect from light Page 4 of 5

5 Preservatives Collection and Transportation for 24-Hour Specimens (continued) The conditions and concentrations of urine preservatives are defined for 24-hour collections as follows: Ambient Room temperature (21 25 degrees C) Refrigerated 4 degrees C Frozen -20 degrees C 6N HCl 30 ml per 24-hour collection 25 ml per 24-hour collection Na 2 CO 3 (crystals) 5 g per 24-hour collection Toluene 30 ml per 24-hour collection 6N HNO 3 15 ml per 24-hour collection (crystals) 10 g per 24-hour collection Thymol (10% in isopropanol) 10 ml per 24-hour collection Preservative and condition guidelines have been evaluated specifically for Mayo Clinic Laboratories assays. If you have questions regarding the use of preservatives, contact Mayo Clinic Laboratories at or Page 5 of 5