The Future of Skin Electronics

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1 Swedish-Japanese Joint Symposium Continuous health status monitoring of elderly people using flexible skin patch sensors Japan Prof. Takao Someya (PL) (The University of Tokyo) Dr. Hiroshi Kajitani (NEC Corporation) Sweden Prof. Magnus Berggren (PL) (Linkoping University) Dr. Tryggve Ljung (AbbVie AB) Dr. Björn Garplind (Invisense AB) Dr. Göran Gustafsson (RISE Acreo) Dr. Michael Peolsson (RISE SICS) 1 The Future of Skin Electronics Movie 2

2 Population in 1, The arrival of super aged society in Japan years old -14 years old Projection Aging rate (>65 years old) 65 years old and older Data: Cabinet Office, Government Of Japan, Ministry of Internal Affairs and Communications, National Institute of Population and Social Security Research, and Ministry of Health, Labor and Welfare, Japan. (%) Aging in Japan Super-aged in 27 Aging rate 27.3% in 217 >3% in 225 Super-aged, Worldwide (Moody s) 13 countries by countries by 23 Innovation for healthy longevity society and social system reform are urgently required. 3 Accessibility to information A safe and comfortable society will be realized when anyone can monitor biometric information easily, accurately, anytime, and anywhere. 4

3 Display Inorganic LED Science 325, 21 (29). OLED Physical sensor Epidermal electronics Science 333, 838 (211). Imperceptible electronics Skin electronics EMG Sensor EEG PNAS 112, 392 (215). Chemical sensor ECG UV Adv. Funct. Mater. 27, (217). Microfluidic Skin battery Bio-fuel cell Energy Adv. Healt Mater. 4, 56 (215). Sci. Adv. 2, e (216). QLED Nature 499, 458 (213). Pressure Adv. Mater., 25, 2773 (213). Hydration Sci. Rep., 4, 674 (214). Blood oxygenation Sci. Transl. Med. 8, 366ra165 (216) Sweat Energy Environ. Sci. 1, 1581 (217). System Human interface Adv. Mater. 29, 1 (217). Micro LED Nat. Com., 4, 1859 (213). Temperature IEEE Trans. Biomed. Eng., 6, 2848 (213). Skin modulus Sci. Adv. 2, e (216). Sci. Adv. 2, e (216). Strain Nature, 529, 59 (216). Healing Proc. of the 216 ACM ISWC, 16 (216). Memory Adv. Mater. 29, (217). Nat. Mater., 12, 938 (213). Nat. Mater., 14, (215). Nat. Mater., 11, 795 (212). Adv. Healthc. Mater. 3, 1597 (214). ACS Nano 9, 558 (215). 5 A skin display is an array of micro-leds embedded in a thin rubber sheet. We have developed a skin display with stretchability of 45%. 6

4 Fabrication process and mechanical durability Stretchable Ag wires Lamination Micro LED Pre-stretched rubber Relaxation of pre-stretch Ultrathin substrate Buckling R/R Cyclic stretching tests The number of cycles Strain 3% New method Conventional 7 A skin display attached to the hand A skin display can be nicely fitted on the skin due to its stretchability. It exhibits simple graphics with motion including a electrocardiogram waveform measured with skin sensors. 8

5 on a hand It firmly adheres to the shape of the skin. It is ultrathin and lightweight. A natural skin respiration is realized. There is no sense of fit. 9 Process flow 1. A nanomesh is made of polyvinyl-alcohol (PVA) by an electrospinning method. 2. Gold patterns are formed by vacuum evaporation through a shadow mask. 3. are laminated onto the skin with dissolving PVA by spraying water. Au PVA Spraying Water Skin Au Nature Nanotechnology (217). DOI: 1.138/nnano A nanomesh adheres to the skin. 1

6 Skin sensors with nanomesh electrodes on a fingertip on a silicone skin 1mm 5 μm Sweat & sweat pores A sweat pore A high level of conformability 1mm 5 μm 11 Biocompatibility test Three samples were attached to the forearm for a week. silicone (1 mm thick) parylene (1 μm thick) nanomesh conductors doubtful positive reaction negative reaction (= No inflammation) 1 mm forearm silicone (1 mm thick) parylene (1 μm thick) nanomesh conductors Dermatitis evaluate different substrates according to the patch test criteria of the ICDRG *. * International Contact Dermatitis Research Group 12

7 Skin sensor to measure electrocardiogram A wireless module for transmitting data to a smartphone attached on the body 1 Electrocardiogram waveform Real-time monitoring by a smartphone ECG Time (s) 1 ECG Elastic conductor A belly band e-textile Time (s) 13 A health-monitoring system with skin electronics Data collections Comfortable Accurate Safe Cloud AI-assisted diagnosis Feedback Natural Intuitive Safe Cyberspace Skin sensors Skin displays # Real space Smart phone Family Nursing stuff home hospital home A skin sensor system combined with skin display can realize a natural flow from measurement of biometric signals to display of information. # A waveform stored in memory was exhibited on a skin display in this work. 14

8 Overview of this project Schedule of the project Promote social implementation by technologies to reduce discomfort in wearable devices and realize a healthy life for elderly people NEC would like to contribute to improving the practicality of physical sensors developed at the Univ. of Tokyo by providing wireless and packaging technologies. 16

9 Summary The new-type wearable sensors with excellent wearing feeling have been developed by using skin electronics. A wireless module for skin sensors has been miniaturized and data collection platform has been developed. We will conduct a sensing test integrating with Swedish chemical sensors. 25 Acknowledgements This research is supported by JST and VINNOVA. Kajitani, NEC Endo, NEC Yokota, UT Nakahara, NEC Yorozu NEC Someya, UT Berggren 26

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