Health Care in the Digital Age

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1 Health Care in the Digital Age Anna Barker Director, Transformative Healthcare Networks, ASU Atul Butte Director, Institute of Computational Health Sciences, UCSF John Chen Chairman and CEO, BlackBerry Victor Dzau President, Institute of Medicine, National Academy of Science Patrick Soon-Shiong Chairman and CEO, NantWorks, LLC Michael Milken Chairman, Milken Institute

2 The principal forces shaping biomedical R&D and healthcare delivery Molecular diagnostics Sensors Molecular (precision) medicine Panomics profiling Integrated analytics of biological networks Device-based medicine Remote health monitoring Telemedicine Information-based healthcare m.health/e.health Data- and evidencebased decisions and Rx selection Outcomes-based healthcare and sustainable health New value propositions, new business models and services BIG DATA #MIGlobal Source: Complex Adaptive Systems, ASU.

3 Precision medicine: understanding molecular signaling (information) pathways in health and disease Genomics Proteomics Molecular pathways and networks Network regulatory mechanisms ID of causal relationships between network perturbations and disease subtypes Patient-specific signals and signatures of disease or predisposition to disease and targeted Rx #MIGlobal Source: Complex Adaptive Systems, ASU.

4 Lab-On-Me and Lab-Always-On dissolvable electronics and biodegradable sensors Dissolution of electronic circuits in physiological conditions Construction from water-soluble, non-standard electronic materials with specific dissolution rates #MIGlobal Source: Complex Adaptive Systems, ASU.

5 m.health Real time remote health monitoring and chronic disease management Lifestyle and fitness Information for proactive health awareness (wellness) #MIGlobal Source: Complex Adaptive Systems, ASU.

6 Increasing Number Of Data Breaches In Healthcare 23% increase in data breaches in healthcare from FBI In 2014, the FBI warned the healthcare industry that the possibilities of increased cyber intrusions is likely. #1 Healthcare data breaches accounted for the largest % all data breaches in the last 4 years 1. 72% of healthcare organizations are not confident or are only somewhat confident in the security and privacy of patient data shared on HIEs 2. #MIGlobal Sources: Symantec ISTR, Ponemon Institute Research Report.

7 The High Cost Of Data Breaches In Healthcare $50K fine per HIPPA violation or up to $1.5M per calendar year per identical violation. +50% of recent hospital patients are willing to switch healthcare providers if their current provider undergoes a data breach 1. $20B In 2014, medical identity theft cost consumers $20B in outof-pocket costs 2. Lawsuits and remediation costs can be more expensive than fines and they are uncapped. 65% of recent hospital patients would avoid healthcare providers that experience a data breach x The black market value of personal health records is $500 per record, compared to $5 for personal credit card information. #MIGlobal Sources: TransUnion Healthcare Report, Fifth Annual Study on Medical Identity Theft.

8 Recent Data Breaches In Healthcare Anthem, Feb 2015 $100M+ cost. 80M impacted. Premera, Jan class action lawsuits, seeking unidentified damages. And Premara are now offering all customers two years of free credit monitoring and identity theft protection services, including identity theft insurance. 11M impacted. Community Health Systems, Aug 2014 $75M-$100M cost. 5.4M impacted. #MIGlobal

9 The Importance Of mhealth Total spending on healthcare was 17% of GDP in 2012 and is expected to increase to 22% of GDP by It is estimated that there will be a 12.9M shortage of health-care workers by 2035; today that figure stands at 7.2M 1. 70% of treatment delays and sentinel events are due to communication breakdown, in the healthcare architecture. #MIGlobal Source: World Health Organization.

10 Barriers To mhealth DECENTRALIZED INFRASTRUCTURE: There are many systems for patient data and records and every one of these needs a special connector. TELEHEALTH POLICY IS NOT UBIQUITOUS: No two states approach telehealth in the same way. REVERSE INCENTIVES: Private sector healthcare providers make more money if patients come to the hospital more often. COST OF MHEALTH DELIVERY: Who pays? The provider or the patient? APPS: Lack of truly useful apps and efficient regulation of apps. FEAR OF NEW PRACTICES / PROCESSES: Risk averse and time constrained industry. #MIGlobal

11 Barriers To mhealth 56% say they lack budget to adopt mobile % are resistant to using a smartphone to access patient information because of limited screen size and data entry capabilities 2. 41% say vendor immaturity is a barrier 1. 95% say hospital IT is unwilling to support smartphones on hospital networks due to security risk. However, 98% are using a personal smartphone to communicate to patients and colleagues 2. #MIGlobal Sources: HIMMS Survey, Spyglass Survey.

12 BlackBerry In Healthcare Secure mobile solutions across the continuum of care. #MIGlobal

13 BlackBerry In Healthcare Category Segment Acute Ambulatory Homecare Strategic Partnerships mhealth Imaging Secure Communications EMR/HIS/EHR Medical Reference + Screening Instruments Commercial Apps (Horizontals) BlackBerry (Core Platform, VAS) Mobile App Management Mobile Office Communication & Collaboration Authentication & Access #MIGlobal Representative of BlackBerry Healthcare portfolio as of Feb 2015

14 #MIGlobal Source: Atul Butte.

15 #MIGlobal Source:.

16 #MIGlobal Source:.

17 #MIGlobal Source:.

18 #MIGlobal Source:.

19 #MIGlobal Source:.

20 #MIGlobal Source:.

21 President Obama Calls For Precision Medicine I want the country that eliminated polio and mapped the human genome to lead a new era of medicine one that delivers the right treatment at the right time. -- President Obama State of the State 2015

22 If Hell is where nothing connects, then being in the field of English must be the key to heaven s door! T.S. Eliot We are in the business of finding connections within texts, between texts and contexts, between texts and ourselves, between our readings and the readings of other interpreters.

23 Hell is where nothing connects. T.S. Eliot

24 Technology drives biology. - Anna Barker Co-Director Complex Adaptive Systems Network, Arizona State University 2014 Partnering for Cures

25 The U.S. spends 90 cents of every health dollar on treatment... and less than a dime on prevention and research.

26 Bioscience is more than health Abundant food and clean water Defense against pandemics Shield against bioterrorism Reliable energy supplies Environmental sustainability

27 Star Wars Video

28 Robohand Video

29 Cost of a 1-Minute Phone Call from the U.S. to India 1975 $10 Today $.01 Telecommunications cost to business approaches zero.

30 Download speed In 2000: 1.2 megabits per second (Mbps) Today: 300+ megabits and faster speeds are coming soon. Source: PC World

31 Download speed South Korea will invest $1.5 billion to upgrade its mobile wireless networks for 5G speeds that will be 1,000 times faster than what they have today. How fast is that? South Korea envisions the 5G network being able to download entire movies in a single second. Sources: Los Angeles Times 1/23/14, South Korea's 5G network will shame LTE in the U.S. Source: PC World

32 IBM System 370/168 in megabytes for $8 million Cost per megabyte: $1 million

33 Apple ipad Mini 64 gigabytes for $499 Cost per megabyte: <$0.008 With access to the cloud, you get virtually unlimited storage at close to zero cost.

34 Today, there are more mobile phones 8 billion than people on the planet. Source: Silicon India 2/28/13

35 In 2012, there were 44 million healthcare app downloads. In 2016, there will be an estimated 142 million healthcare app downloads. Source: Juniper Research; Burrill & Company, Capturing Value

36 Whatsapp Active Users (millions) April 2013 August 2013 December 2013 April 2014 August 2014 January 2015 Source: WhatsApp

37 Duke University: 2015 National Champions

38 A Big Data Medical Research Lab?

39 Hospital Room of the Future

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