Microreactor Chips. product datasheet

Transcription

1 Unit 1, Anglian Business Park, Orchard Road, Royston, Hertfordshire, SG8 5TW, UK T: +44 (0) F: +44 (0) E: W: Microreactor Chips Dolomite Microfluidics North America Office Blacktrace Inc, 29 Albion Place Charlestown, MA 02129, USA C: T: F: E: product datasheet page Description 2 Benefits 2 Specifications 3 Performance and Geometry Information 4 Channel Layout 5 Optical transmission 8 Reactor Chip Header and Accessories 9 Custom Options 10 The Dolomite Centre Limited Page 1 of 11

2 Part name Part number Microreactor Chip 62.5µl, 2 ports Microreactor Chip 62.5µl, 3 ports Microreactor Chip 250µl, 2 ports Microreactor Chip 250µl, 3 ports Quartz Microreactor Chip 250µl, 3 ports Microreactor Chip 1ml, 2 ports Microreactor Chip 1ml, 3 ports Description The Microreactor Chips are glass microfluidic devices designed for mixing and reaction of two or three liquid reagent streams. The main application is solution phase chemistry experiments including compound synthesis and reaction kinetics studies. The chips are supplied in a chip holder. A chip header is also available (Part No ) allowing quick connection to 1/16 fluid pipes. Left: 250 µl and 62.5 µl Microreactor Chips without holder Below: 1 ml Microreactor Chip without holder Below right: Microreactor Chip in holder and chip header (Part No ) Benefits Rapid mixing across a range of flow rates High visibility (excellent access for optics) 2 or 3 inputs Quick connect/disconnect Wide temperature and pressure range Excellent chemical compatibility MAR _v.A.4 Page 2 of 11

3 Specifications Specification Value Number of inputs 2-3 Number of outputs 1 Reaction volume 62.5µl, 250µl, 1000µl Outside diameter of connection tubing Inside diameter of connection tubing Connection tubing material Surface roughness of channels (Ra) Chip size Chip thickness Max operating temperature Material Fabrication process 1.6mm (1/16inch) 0.25mm, 0.5mm, 0.8mm PTFE, FEP 5nm 90mm x 28mm and 90mm x 45mm 4.5mm 150 ºC* Glass/Quartz HF etching and thermal bonding *Contact Dolomite for higher temperature options MAR _v.A.4 Page 3 of 11

4 Performance and Geometry Information Specification Chip type Value 62.5µl Reaction chip 250µl Reaction chip 250µl Reaction chip 1000µl Reaction chip Part number (2 input) (3 input) (2 input) (3 input) (3 input) (2 input) Material Glass Glass Quartz Glass Operating pressure Back pressure with 100l/min flow (water) 30Bar 30Bar 30Bar 10Bar 4Bar 0.25Bar 0.25Bar 0.03Bar (3 input) Mixing time 6 seconds 10 seconds 10 seconds 10 seconds Preheating of reagents prior to mixing No No No No Channel Crosssection depth width length Reaction channel depth Reaction channel width Reaction channel length 85µm 250µm 250µm 1240µm 220µm 300µm 300µm 161µm 532mm 532mm 532mm 536mm 85µm 250µm 250µm 1240µm 370µm 400µm 400µm 391µm 1912mm 2509mm 2509mm 1844mm MAR _v.A.4 Page 4 of 11

5 Channel Layout for 62.5µl and 250µl 2 port Microreactor Chips Reaction channel Fluid input 1 Fluid input 2 Double-T mixing junction Fluid output Double-T mixing junction MAR _v.A.4 Page 5 of 11

6 Channel Layout for 62.5µl and 250µl 3 port Microreactor Chips Fluid input 1 Reaction channel Fluid input 2 Double-T mixing junction Fluid input 3 Fluid output Double-T mixing junction MAR _v.A.4 Page 6 of 11

7 Channel Layout for Microreactor Chip 1ml, 2 ports Fluid input 1 Reaction channel Fluid input 2 T mixing junction Fluid output Channel Layout for Microreactor Chip 1ml, 3 ports Fluid input 1 Reaction channel Fluid input 2 T mixing junction Fluid input 3 Fluid output MAR _v.A.4 Page 7 of 11

8 Figure 1 Mixing of 0.1 M NaOH with ph indicator in water Optical Transmission Spectral Transmittance of 2mm glass layer 100 Transmittance, % Wavelength, nm Optical Transmission of Glass ( , , , , and ) MAR _v.A.4 Page 8 of 11

9 Optical Transmission of Synthetic Quartz Viosil-SQ ( ) Reactor Chip Header (Part No ) and other accessories Reactor Chip Header (Part No ): Enables the alignment and connection of all the input and output pipes to the Microreactor in seconds. The header is secured to the chip and holder by the two knurled thumb screws. Chip Header Seal (Part No ): Make the seal between the Microreactor and the input/output pipes held in the Mitos Chip Header. They are made of extremely chemically resistant fluoroelastomer (FFKM) and create a "zero" dead volume seal rated to 20bar (300psi). Chip Header Blanking Plug (Part No ): Used to seal off inputs to the chip. This enables a 3 input chip to be used with 1 or 2 inputs and a 2 input chip to be used with just 1 input. The blanking plug inserts into the Chip Header in place of an input pipe and should be used with a Chip Header Seal. Left: Reactor Chip Header (Part No ) Top Right: Plug FEP Pack of 10 (Part No ) Bottom Right: Chip Header FFKM Seals x10 (Part No ) MAR _v.A.4 Page 9 of 11

10 Custom Options The microreactor chips may be customised in the following ways: Channel depth may be increased or decreased The chips can be made in quartz to improve UV light transmission Hydrophobic surface coatings can be applied to the inside surface of the channels Metals layers may be deposited on the inside surface of the channels, examples include platinum and gold layers Microreactor Chip with metal layer on channel surface MAR _v.A.4 Page 10 of 11

11 MAR _v.A.4 Page 11 of 11