HST.583 Functional Magnetic Resonance Imaging: Data Acquisition and Analysis Fall 2006
|
|
- Arnold Trevor Hill
- 5 years ago
- Views:
Transcription
1 MIT OpenCourseWare HST.583 Functional Magnetic Resonance Imaging: Data Acquisition and Analysis Fall 2006 For information about citing these materials or our Terms of Use, visit:
2 HST.583: Functional Magnetic Resonance Imaging: Data Acquisition and Analysis, Fall 2006 Harvard-MIT Division of Health Sciences and Technology Course Director: Dr. Randy Gollub. Statistical Signal Processing for fmri Douglas N. Greve Mark Vangel Anastasia Yendiki
3 Overview First-Level Univariate Analysis Signal Modeling Nuisance Modeling Noise Modeling Hypothesis Testing Correction for Multiple Comparisons Cross-Subject/Higher Level Analysis Lab
4 Analysis Goals Quantify Neural Correlates in fmri Amplitude of Hemodynamic Response Delay/Shape of Hemodynamic Response Extent/Size of Activation Localization of function Quantify Uncertainty Cross-subject (within group) Cross-group eg, Normals, Clinical Populations Within-subject EEG/MEG/Optical/Surgical Planning
5 Challenges Large Noise thermal, physiological, motion Small Signal delay, dispersion Structural/Functional Alignment within subject Intersubject Alignment Copious amounts of data eg, 20 subjects, 5 runs per subject, 100 time points per run, 64x64x30 volume = 1.2G data points More spatial voxels than time points (multiple comparisons problem). Model Validation
6 Method Correlational synchronized stimulus and acquistion Linear/Gaussian Assumptions GLM General Linear Model MSE Minimum Square Error LMS Least Mean Squares Massively Univariate
7 Hemodynamic Response (BOLD) Time-to-Peak (~6sec) Dispersion TR (~2sec) Equilibrium (~16-32sec) Undershoot Delay (~1-2sec)
8 fmri Noise Synthetic data.
9 Averaging Synthetic data.
10 Typical Analysis Stream Preprocessing Univariate First-Level GLM Analysis Univariate Higher-Level GLM Analysis Multivariate Analysis Packages: SPM Statistical Parametric Mapping AFNI Analysis of Functional NeuroImages FSL fmri Software Library FS-FAST FreeSurfer Functional Analysis STream
11 Preprocessing k-space reconstruction Slice-Timing Correction (?) Motion Correction Spatial Filtering (Smoothing - FWHM) Intensity Normalization Temporal Filtering (or in analysis) Per-run, within subject
12 Univariate First-Level Analysis Per-voxel, per-subject Postulate model of the observable (ie raw time course) Signal model (eg, hemodynamic response) Noise model (eg, autocorrelation function) Drift (eg, mean offset, linear, quadratic) General Linear Model (GLM) Parameterized Linear (superposition) Least-mean-square estimation of parameters Hypothesis Test = Contrast of Parameters Assemble into a map
13 Univariate High-level Analysis Per-voxel, Cross-subject Requires intersubject registration Dave Kennedy Uses information from First/Lower Levels GLM to describe relationship Random Effects Fixed Effects
14 Multivariate Statistics Cross-voxel (within map) Thresholding and multiple comparisons problem Gaussian Random Fields (GRF) Principal Component Analysis (PCA/SVD) Independent Component Analysis Region-of-Interest
15
16 Hemodynamic Response Model Time-to-Peak (~6sec) Dispersion TR (~2sec) Equilibrium (~16-32sec) Undershoot Delay (~1-2sec)
17 Visual Activation Paradigm Flickering Checkerboard Visual, Auditory, Motor, Tactile, Pain, Perceptual, Recognition, Memory, Emotion, Reward/Punishment, Olfactory, Taste, Gastral, Gambling, Economic, Acupuncture, Meditation, The Pepsi Challenge, Scientific Clinical Pharmaceutical
18 Blood Oxygen Level Dependence (BOLD) Oxygenated Hemoglobin (DiaMagnetic) Neurons Lungs Deoxygenated Hemoglobin (ParaMagnetic) Oxygen CO2
19 Functional MRI (fmri) Stimulus Localized Neural Firing Localized Increased Blood Flow Localized BOLD Changes Sample BOLD response in 4D Space (3D) voxels (64x64x35, 3x3x5mm^3) Time (1D) time points (100, 2 sec) Time 1 Time 2 Time 3
20 Analysis Goals Given: raw fmri time course and stimulus presentation times Compute: Hemodynamic Response (HRF) Amplitude HRF Confidence Interval } P-Value Quantify Uncertainty Noise Amplitude
21 Final Results: Maps Assign values to each voxel Display as pseudo-color images Threshold?
22 Final Results: Tables List of active regions Cluster TalX TalY TalZ Volume Sig Number (mm) (mm) (mm) (mm^3) (log10)
23 Final Results: Waveforms Average raw data over time and space
Introduction to Neuroimaging Janaina Mourao-Miranda
Introduction to Neuroimaging Janaina Mourao-Miranda Neuroimaging techniques have changed the way neuroscientists address questions about functional anatomy, especially in relation to behavior and clinical
More informationHST.583 Functional Magnetic Resonance Imaging: Data Acquisition and Analysis Fall 2008
MIT OpenCourseWare http://ocw.mit.edu HST.583 Functional Magnetic Resonance Imaging: Data Acquisition and Analysis Fall 2008 For information about citing these materials or our Terms of Use, visit: http://ocw.mit.edu/terms.
More informationStatistical Analysis of Neuroimaging Data. Phebe Kemmer BIOS 516 Sept 24, 2015
Statistical Analysis of Neuroimaging Data Phebe Kemmer BIOS 516 Sept 24, 2015 Review from last time Structural Imaging modalities MRI, CAT, DTI (diffusion tensor imaging) Functional Imaging modalities
More informationFunction-Structure Integration in FreeSurfer
Function-Structure Integration in FreeSurfer Outline Function-Structure Integration Function-Structure Registration in FreeSurfer fmri Analysis Preprocessing First-Level Analysis Higher-Level (Group) Analysis
More informationFMRI Pre-Processing and Model- Based Statistics
FMRI Pre-Processing and Model- Based Statistics Brief intro to FMRI experiments and analysis FMRI pre-stats image processing Simple Single-Subject Statistics Multi-Level FMRI Analysis Advanced FMRI Analysis
More informationHST.583 Functional Magnetic Resonance Imaging: Data Acquisition and Analysis Fall 2008
MIT OpenCourseWare http://ocw.mit.edu HST.583 Functional Magnetic Resonance Imaging: Data Acquisition and Analysis Fall 2008 For information about citing these materials or our Terms of Use, visit: http://ocw.mit.edu/terms.
More informationfmri Image Preprocessing
fmri Image Preprocessing Rick Hoge, Ph.D. Laboratoire de neuroimagerie vasculaire (LINeV) Centre de recherche de l institut universitaire de gériatrie de Montréal, Université de Montréal Outline Motion
More informationSPM8 for Basic and Clinical Investigators. Preprocessing. fmri Preprocessing
SPM8 for Basic and Clinical Investigators Preprocessing fmri Preprocessing Slice timing correction Geometric distortion correction Head motion correction Temporal filtering Intensity normalization Spatial
More informationFunctional MRI in Clinical Research and Practice Preprocessing
Functional MRI in Clinical Research and Practice Preprocessing fmri Preprocessing Slice timing correction Geometric distortion correction Head motion correction Temporal filtering Intensity normalization
More informationAnalysis of Functional MRI Timeseries Data Using Signal Processing Techniques
Analysis of Functional MRI Timeseries Data Using Signal Processing Techniques Sea Chen Department of Biomedical Engineering Advisors: Dr. Charles A. Bouman and Dr. Mark J. Lowe S. Chen Final Exam October
More informationBasic Introduction to Data Analysis. Block Design Demonstration. Robert Savoy
Basic Introduction to Data Analysis Block Design Demonstration Robert Savoy Sample Block Design Experiment Demonstration Use of Visual and Motor Task Separability of Responses Combined Visual and Motor
More informationFSL Pre-Processing Pipeline
The Art and Pitfalls of fmri Preprocessing FSL Pre-Processing Pipeline Mark Jenkinson FMRIB Centre, University of Oxford FSL Pre-Processing Pipeline Standard pre-processing: Task fmri Resting-state fmri
More informationBasic fmri Design and Analysis. Preprocessing
Basic fmri Design and Analysis Preprocessing fmri Preprocessing Slice timing correction Geometric distortion correction Head motion correction Temporal filtering Intensity normalization Spatial filtering
More informationSPM8 for Basic and Clinical Investigators. Preprocessing
SPM8 for Basic and Clinical Investigators Preprocessing fmri Preprocessing Slice timing correction Geometric distortion correction Head motion correction Temporal filtering Intensity normalization Spatial
More informationEPI Data Are Acquired Serially. EPI Data Are Acquired Serially 10/23/2011. Functional Connectivity Preprocessing. fmri Preprocessing
Functional Connectivity Preprocessing Geometric distortion Head motion Geometric distortion Head motion EPI Data Are Acquired Serially EPI Data Are Acquired Serially descending 1 EPI Data Are Acquired
More informationIndependent Component Analysis of fmri Data
Independent Component Analysis of fmri Data Denise Miller April 2005 Introduction Techniques employed to analyze functional magnetic resonance imaging (fmri) data typically use some form of univariate
More informationHST.583 Functional Magnetic Resonance Imaging: Data Acquisition and Analysis Fall 2006
MIT OpenCourseWare http://ocw.mit.edu HST.583 Functional Magnetic Resonance Imaging: Data Acquisition and Analysis Fall 2006 For information about citing these materials or our Terms of Use, visit: http://ocw.mit.edu/terms.
More informationAnalysis of fmri data within Brainvisa Example with the Saccades database
Analysis of fmri data within Brainvisa Example with the Saccades database 18/11/2009 Note : All the sentences in italic correspond to informations relative to the specific dataset under study TP participants
More informationINDEPENDENT COMPONENT ANALYSIS APPLIED TO fmri DATA: A GENERATIVE MODEL FOR VALIDATING RESULTS
INDEPENDENT COMPONENT ANALYSIS APPLIED TO fmri DATA: A GENERATIVE MODEL FOR VALIDATING RESULTS V. Calhoun 1,2, T. Adali, 2 and G. Pearlson 1 1 Johns Hopkins University Division of Psychiatric Neuro-Imaging,
More informationIntroduc)on to fmri. Natalia Zaretskaya
Introduc)on to fmri Natalia Zaretskaya Content fmri signal fmri versus neural ac)vity A classical experiment: flickering checkerboard Preprocessing Univariate analysis Single- subject analysis Group analysis
More informationBayesian Inference in fmri Will Penny
Bayesian Inference in fmri Will Penny Bayesian Approaches in Neuroscience Karolinska Institutet, Stockholm February 2016 Overview Posterior Probability Maps Hemodynamic Response Functions Population
More informationJournal of Articles in Support of The Null Hypothesis
Data Preprocessing Martin M. Monti, PhD UCLA Psychology NITP 2016 Typical (task-based) fmri analysis sequence Image Pre-processing Single Subject Analysis Group Analysis Journal of Articles in Support
More informationNA-MIC National Alliance for Medical Image Computing fmri Data Analysis
NA-MIC fmri Data Analysis Sonia Pujol, Ph.D. Wendy Plesniak, Ph.D. Randy Gollub, M.D., Ph.D. Acknowledgments NIH U54EB005149 Neuroimage Analysis Center NIH P41RR013218 FIRST Biomedical Informatics Research
More informationFSL Pre-Processing Pipeline
The Art and Pitfalls of fmri Preprocessing FSL Pre-Processing Pipeline Mark Jenkinson FMRIB Centre, University of Oxford FSL Pre-Processing Pipeline Standard pre-processing: Task fmri Resting-state fmri
More information7/15/2016 ARE YOUR ANALYSES TOO WHY IS YOUR ANALYSIS PARAMETRIC? PARAMETRIC? That s not Normal!
ARE YOUR ANALYSES TOO PARAMETRIC? That s not Normal! Martin M Monti http://montilab.psych.ucla.edu WHY IS YOUR ANALYSIS PARAMETRIC? i. Optimal power (defined as the probability to detect a real difference)
More informationFirst-level fmri modeling
First-level fmri modeling Monday, Lecture 3 Jeanette Mumford University of Wisconsin - Madison What do we need to remember from the last lecture? What is the general structure of a t- statistic? How about
More informationArtifact detection and repair in fmri
Artifact detection and repair in fmri Paul K. Mazaika, Ph.D. Center for Interdisciplinary Brain Sciences Research (CIBSR) Division of Interdisciplinary Behavioral Sciences Stanford University School of
More informationTime-Frequency Method Based Activation Detection in Functional MRI Time-Series
Time-Frequency Method Based Activation Detection in Functional MRI Time-Series Arun Kumar 1,2 and Jagath C. Rajapakse 1,3 1 School of Computing, NTU, Singapore 2 School of EEE,Singapore Polytechnic, Singapore
More informationSPATIO-TEMPORAL DATA ANALYSIS WITH NON-LINEAR FILTERS: BRAIN MAPPING WITH fmri DATA
Image Anal Stereol 2000;19:189-194 Original Research Paper SPATIO-TEMPORAL DATA ANALYSIS WITH NON-LINEAR FILTERS: BRAIN MAPPING WITH fmri DATA KARSTEN RODENACKER 1, KLAUS HAHN 1, GERHARD WINKLER 1 AND
More informationCS 229 Final Project Report Learning to Decode Cognitive States of Rat using Functional Magnetic Resonance Imaging Time Series
CS 229 Final Project Report Learning to Decode Cognitive States of Rat using Functional Magnetic Resonance Imaging Time Series Jingyuan Chen //Department of Electrical Engineering, cjy2010@stanford.edu//
More informationMultivariate pattern classification
Multivariate pattern classification Thomas Wolbers Space & Ageing Laboratory (www.sal.mvm.ed.ac.uk) Centre for Cognitive and Neural Systems & Centre for Cognitive Ageing and Cognitive Epidemiology Outline
More informationFunctional MRI. Jerry Allison, Ph. D. Medical College of Georgia
Functional MRI Jerry Allison, Ph. D. Medical College of Georgia BOLD Imaging Technique Blood Oxygen Level Dependent contrast can be used to map brain function Right Hand Motor Task Outline fmri BOLD Contrast
More informationTutorial BOLD Module
m a k i n g f u n c t i o n a l M R I e a s y n o r d i c B r a i n E x Tutorial BOLD Module Please note that this tutorial is for the latest released nordicbrainex. If you are using an older version please
More informationExperimental Design for fmri OHBM Advanced fmri Educational Course Thomas Liu UCSD Center for Func6onal MRI
Experimental Design for fmri OHBM Advanced fmri Educational Course 2014 Thomas Liu UCSD Center for Func6onal MRI Experimental Design Design 1 Condition 1 Condition 2 Condition 3 Design 2 Why worry about
More informationHST.583 Functional Magnetic Resonance Imaging: Data Acquisition and Analysis Fall 2008
MIT OpenCourseWare http://ocw.mit.edu HST.583 Functional Magnetic Resonance Imaging: Data Acquisition and Analysis Fall 2008 For information about citing these materials or our Terms of Use, visit: http://ocw.mit.edu/terms.
More informationMultiple Testing and Thresholding
Multiple Testing and Thresholding UCLA Advanced NeuroImaging Summer School, 2007 Thanks for the slides Tom Nichols! Overview Multiple Testing Problem Which of my 100,000 voxels are active? Two methods
More informationI.e. Sex differences in child appetitive traits and Eating in the Absence of Hunger:
Supplementary Materials I. Evidence of sex differences on eating behavior in children I.e. Sex differences in child appetitive traits and Eating in the Absence of Hunger: Table 2. Parent Report for Child
More informationThe organization of the human cerebral cortex estimated by intrinsic functional connectivity
1 The organization of the human cerebral cortex estimated by intrinsic functional connectivity Journal: Journal of Neurophysiology Author: B. T. Thomas Yeo, et al Link: https://www.ncbi.nlm.nih.gov/pubmed/21653723
More informationBias in Resampling-Based Thresholding of Statistical Maps in fmri
Bias in Resampling-Based Thresholding of Statistical Maps in fmri Ola Friman and Carl-Fredrik Westin Laboratory of Mathematics in Imaging, Department of Radiology Brigham and Women s Hospital, Harvard
More informationCorrection for multiple comparisons. Cyril Pernet, PhD SBIRC/SINAPSE University of Edinburgh
Correction for multiple comparisons Cyril Pernet, PhD SBIRC/SINAPSE University of Edinburgh Overview Multiple comparisons correction procedures Levels of inferences (set, cluster, voxel) Circularity issues
More informationEMPIRICALLY INVESTIGATING THE STATISTICAL VALIDITY OF SPM, FSL AND AFNI FOR SINGLE SUBJECT FMRI ANALYSIS
EMPIRICALLY INVESTIGATING THE STATISTICAL VALIDITY OF SPM, FSL AND AFNI FOR SINGLE SUBJECT FMRI ANALYSIS Anders Eklund a,b,c, Thomas Nichols d, Mats Andersson a,c, Hans Knutsson a,c a Department of Biomedical
More informationFunctional MRI data preprocessing. Cyril Pernet, PhD
Functional MRI data preprocessing Cyril Pernet, PhD Data have been acquired, what s s next? time No matter the design, multiple volumes (made from multiple slices) have been acquired in time. Before getting
More informationHST.583 Functional Magnetic Resonance Imaging: Data Acquisition and Analysis Fall 2008
MIT OpenCourseWare http://ocw.mit.edu HST.583 Functional Magnetic Resonance Imaging: Data Acquisition and Analysis Fall 2008 For information about citing these materials or our Terms of Use, visit: http://ocw.mit.edu/terms.
More informationMultivariate Pattern Classification. Thomas Wolbers Space and Aging Laboratory Centre for Cognitive and Neural Systems
Multivariate Pattern Classification Thomas Wolbers Space and Aging Laboratory Centre for Cognitive and Neural Systems Outline WHY PATTERN CLASSIFICATION? PROCESSING STREAM PREPROCESSING / FEATURE REDUCTION
More informationWavelet-Based Statistical Analysis in Functional Neuroimaging
Proceedings of the 6th WSEAS International Conference on Wavelet Analysis & Multirate Systems, Bucharest, Romania, October 16-18, 2006 59 Wavelet-Based Statistical Analysis in Functional Neuroimaging RADU
More informationMultiple Testing and Thresholding
Multiple Testing and Thresholding NITP, 2009 Thanks for the slides Tom Nichols! Overview Multiple Testing Problem Which of my 100,000 voxels are active? Two methods for controlling false positives Familywise
More informationA Data-Driven fmri Neuronal Activation Analysis Method Using Temporal Clustering Technique and an Adaptive Voxel Selection Criterion
A Data-Driven fmri Neuronal Activation Analysis Method Using Temporal Clustering Technique and an Adaptive Voxel Selection Criterion Sarah Lee, Fernando Zelaya, Stephanie A. Amiel and Michael J. Brammer
More informationHST.583 Functional Magnetic Resonance Imaging: Data Acquisition and Analysis Fall 2008
MIT OpenCourseWare http://ocw.mit.edu HST.583 Functional Magnetic Resonance Imaging: Data Acquisition and Analysis Fall 2008 For information about citing these materials or our Terms of Use, visit: http://ocw.mit.edu/terms.
More informationMulti-voxel pattern analysis: Decoding Mental States from fmri Activity Patterns
Multi-voxel pattern analysis: Decoding Mental States from fmri Activity Patterns Artwork by Leon Zernitsky Jesse Rissman NITP Summer Program 2012 Part 1 of 2 Goals of Multi-voxel Pattern Analysis Decoding
More informationIntroduction to fmri. Pre-processing
Introduction to fmri Pre-processing Tibor Auer Department of Psychology Research Fellow in MRI Data Types Anatomical data: T 1 -weighted, 3D, 1/subject or session - (ME)MPRAGE/FLASH sequence, undistorted
More informationfmri Data Analysis Techniques and the Self-Organizing Maps Approach
fmri Data Analysis Techniques and the Self-Organizing Maps Approach Tiago José de Oliveira Jordão Instituto Superior Técnico Pólo do Taguspark, Porto Salvo, Portugal Functional Magnetic Resonance Imaging
More informationIntroductory Concepts for Voxel-Based Statistical Analysis
Introductory Concepts for Voxel-Based Statistical Analysis John Kornak University of California, San Francisco Department of Radiology and Biomedical Imaging Department of Epidemiology and Biostatistics
More informationAn Empirical Comparison of SPM Preprocessing Parameters to the Analysis of fmri Data
NeuroImage 17, 19 28 (2002) doi:10.1006/nimg.2002.1113 An Empirical Comparison of SPM Preprocessing Parameters to the Analysis of fmri Data Valeria Della-Maggiore, Wilkin Chau, Pedro R. Peres-Neto,* and
More informationPreprocessing of fmri data
Preprocessing of fmri data Pierre Bellec CRIUGM, DIRO, UdM Flowchart of the NIAK fmri preprocessing pipeline fmri run 1 fmri run N individual datasets CIVET NUC, segmentation, spatial normalization slice
More informationSupplementary Figure 1. Decoding results broken down for different ROIs
Supplementary Figure 1 Decoding results broken down for different ROIs Decoding results for areas V1, V2, V3, and V1 V3 combined. (a) Decoded and presented orientations are strongly correlated in areas
More informationSPM Introduction. SPM : Overview. SPM: Preprocessing SPM! SPM: Preprocessing. Scott Peltier. FMRI Laboratory University of Michigan
SPM Introduction Scott Peltier FMRI Laboratory University of Michigan! Slides adapted from T. Nichols SPM! SPM : Overview Library of MATLAB and C functions Graphical user interface Four main components:
More informationVersion. Getting Started: An fmri-cpca Tutorial
Version 11 Getting Started: An fmri-cpca Tutorial 2 Table of Contents Table of Contents... 2 Introduction... 3 Definition of fmri-cpca Data... 3 Purpose of this tutorial... 3 Prerequisites... 4 Used Terms
More informationHST.583 Functional Magnetic Resonance Imaging: Data Acquisition and Analysis
MIT OpenCourseWare http://ocw.mit.edu Functional Magnetic Resonance Imaging: Data Acquisition and Analysis Fall 2008 For information about citing these materials or our Terms of Use, visit: http://ocw.mit.edu/terms.
More informationA Novel Information Theoretic and Bayesian Approach for fmri data Analysis
Proceedings of SPIE Medical Imaging 23, San Diego, CA, February 23. A Novel Information Theoretic and Bayesian Approach for fmri data Analysis Chandan Reddy *a, Alejandro Terrazas b,c a Department of Computer
More informationCognitive States Detection in fmri Data Analysis using incremental PCA
Department of Computer Engineering Cognitive States Detection in fmri Data Analysis using incremental PCA Hoang Trong Minh Tuan, Yonggwan Won*, Hyung-Jeong Yang International Conference on Computational
More informationSPM Introduction SPM! Scott Peltier. FMRI Laboratory University of Michigan. Software to perform computation, manipulation and display of imaging data
SPM Introduction Scott Peltier FMRI Laboratory University of Michigan Slides adapted from T. Nichols SPM! Software to perform computation, manipulation and display of imaging data 1 1 SPM : Overview Library
More informationData Visualisation in SPM: An introduction
Data Visualisation in SPM: An introduction Alexa Morcom Edinburgh SPM course, April 2010 Centre for Cognitive & Neural Systems/ Department of Psychology University of Edinburgh Visualising results remembered
More informationfmri pre-processing Juergen Dukart
fmri pre-processing Juergen Dukart Outline Why do we need pre-processing? fmri pre-processing Slice time correction Realignment Unwarping Coregistration Spatial normalisation Smoothing Overview fmri time-series
More informationBayesian Inference of Hemodynamic Changes in Functional Arterial Spin Labeling Data
Bayesian Inference of Hemodynamic Changes in Functional Arterial Spin Labeling Data Mark W. Woolrich, 1, * Peter Chiarelli, 1 Daniel Gallichan, 1 Joanna Perthen, 2 and Thomas T. Liu 2 Magnetic Resonance
More informationMultiple Testing and Thresholding
Multiple Testing and Thresholding NITP, 2010 Thanks for the slides Tom Nichols! Overview Multiple Testing Problem Which of my 100,000 voxels are active? Two methods for controlling false positives Familywise
More informationClassification of Whole Brain fmri Activation Patterns. Serdar Kemal Balcı
Classification of Whole Brain fmri Activation Patterns by Serdar Kemal Balcı Submitted to the Department of Electrical Engineering and Computer Science in partial fulfillment of the requirements for the
More informationMedical Image Analysis
Medical Image Analysis Instructor: Moo K. Chung mchung@stat.wisc.edu Lecture 10. Multiple Comparisons March 06, 2007 This lecture will show you how to construct P-value maps fmri Multiple Comparisons 4-Dimensional
More informationDetecting Brain Activations in Functional Magnetic Resonance Imaging (fmri) Experiments with a Maximum Cross-Correlation Statistic
Journal of Data Science 10(2012), 403-418 Detecting Brain Activations in Functional Magnetic Resonance Imaging (fmri) Experiments with a Maximum Cross-Correlation Statistic Kinfemichael Gedif 1, William
More informationStatistical Methods in functional MRI. False Discovery Rate. Issues with FWER. Lecture 7.2: Multiple Comparisons ( ) 04/25/13
Statistical Methods in functional MRI Lecture 7.2: Multiple Comparisons 04/25/13 Martin Lindquist Department of iostatistics Johns Hopkins University Issues with FWER Methods that control the FWER (onferroni,
More informationthe PyHRF package P. Ciuciu1,2 and T. Vincent1,2 Methods meeting at Neurospin 1: CEA/NeuroSpin/LNAO
Joint detection-estimation of brain activity from fmri time series: the PyHRF package Methods meeting at Neurospin P. Ciuciu1,2 and T. Vincent1,2 philippe.ciuciu@cea.fr 1: CEA/NeuroSpin/LNAO www.lnao.fr
More informationSparse sampling in MRI: From basic theory to clinical application. R. Marc Lebel, PhD Department of Electrical Engineering Department of Radiology
Sparse sampling in MRI: From basic theory to clinical application R. Marc Lebel, PhD Department of Electrical Engineering Department of Radiology Objective Provide an intuitive overview of compressed sensing
More informationNonparametric Mean Shift Functional Detection in the Functional Space for Task and Resting-state fmri
Nonparametric Mean Shift Functional Detection in the Functional Space for Task and Resting-state fmri Jian Cheng 1,2, Feng Shi 3, Kun Wang 1, Ming Song 1, Jiefeng Jiang 1, Lijuan Xu 1, Tianzi Jiang 1 1
More informationNeuroImaging. (spatial and statistical processing, maybe) Philippe Peigneux, PhD. UR2NF - Neuropsychology and Functional
NeuroImaging (spatial and statistical processing, maybe) Philippe Peigneux, PhD UR2NF - Neuropsychology and Functional Neuroimaging Research Unit, ULB http://dev.ulb.ac.be/ur2nf/ CREDITS These slides have
More informationCorrection of Partial Volume Effects in Arterial Spin Labeling MRI
Correction of Partial Volume Effects in Arterial Spin Labeling MRI By: Tracy Ssali Supervisors: Dr. Keith St. Lawrence and Udunna Anazodo Medical Biophysics 3970Z Six Week Project April 13 th 2012 Introduction
More informationData Visualisation in SPM: An introduction
Data Visualisation in SPM: An introduction Alexa Morcom Edinburgh SPM course, April 2015 SPMmip [-30, 3, -9] 3 Visualising results remembered vs. fixation contrast(s) < < After the results table - what
More informationSPM Course! Single Subject Analysis
SPM Course! Single Subject Analysis Practical Session Dr. Jakob Heinzle & Dr. Frederike Petzschner & Dr. Lionel Rigoux Hands up: Who has programming experience with Matlab? Who has analyzed an fmri experiment
More informationMODELING AND ESTIMATION OF SIGNALS AND ARTIFACTS IN FUNCTIONAL MAGNETIC RESONANCE IMAGING AND COMPUTED TOMOGRAPHY. Negar Bazargani
MODELING AND ESTIMATION OF SIGNALS AND ARTIFACTS IN FUNCTIONAL MAGNETIC RESONANCE IMAGING AND COMPUTED TOMOGRAPHY by Negar Bazargani APPROVED BY SUPERVISORY COMMITTEE: Dr. Aria Nosratinia, Chair Dr. John
More informationDuring the past decade, many papers have been published
DIGITAL STOCK BY STEPHEN C. STROTHER Evaluating fmri Preprocessing Pipelines Review of Preprocessing Steps for BOLD fmri FUNCTIONAL MAGNETIC RESONANCE IMAGING During the past decade, many papers have been
More informationLocating Motion Artifacts in Parametric fmri Analysis
Tina Memo No. 200-002 Presented at MICCAI 999 Locating Motion Artifacts in Parametric fmri Analysis A.J.Lacey, N.A.Thacker, E. Burton, and A.Jackson Last updated 2 / 02 / 2002 Imaging Science and Biomedical
More informationCS/NEUR125 Brains, Minds, and Machines. Due: Wednesday, April 5
CS/NEUR125 Brains, Minds, and Machines Lab 8: Using fmri to Discover Language Areas in the Brain Due: Wednesday, April 5 In this lab, you will analyze fmri data from an experiment that was designed to
More informationSPM99 fmri Data Analysis Workbook
SPM99 fmri Data Analysis Workbook This file is a description of the steps needed to use SPM99 analyze a fmri data set from a single subject using a simple on/off activation paradigm. There are two parts
More informationA NEURAL NETWORK BASED IMAGING SYSTEM FOR fmri ANALYSIS IMPLEMENTING WAVELET METHOD
6th WSEAS International Conference on CIRCUITS, SYSTEMS, ELECTRONICS,CONTROL & SIGNAL PROCESSING, Cairo, Egypt, Dec 29-31, 2007 454 A NEURAL NETWORK BASED IMAGING SYSTEM FOR fmri ANALYSIS IMPLEMENTING
More informationSpatial Regularization of Functional Connectivity Using High-Dimensional Markov Random Fields
Spatial Regularization of Functional Connectivity Using High-Dimensional Markov Random Fields Wei Liu 1, Peihong Zhu 1, Jeffrey S. Anderson 2, Deborah Yurgelun-Todd 3, and P. Thomas Fletcher 1 1 Scientific
More informationCluster failure: Why fmri inferences for spatial extent have inflated false positive rates
Supporting Information Appendix Cluster failure: Why fmri inferences for spatial extent have inflated false positive rates Anders Eklund, Thomas Nichols, Hans Knutsson Methods Resting state fmri data Resting
More informationSupplementary Figure 1
Supplementary Figure 1 BOLD and CBV functional maps showing EPI versus line-scanning FLASH fmri. A. Colored BOLD and CBV functional maps are shown in the highlighted window (green frame) of the raw EPI
More informationReconstructing visual experiences from brain activity evoked by natural movies
Reconstructing visual experiences from brain activity evoked by natural movies Shinji Nishimoto, An T. Vu, Thomas Naselaris, Yuval Benjamini, Bin Yu, and Jack L. Gallant, Current Biology, 2011 -Yi Gao,
More informationFunctional and dynamic Magnetic Resonance Imaging using vector adaptive weights smoothing
Functional and dynamic Magnetic Resonance Imaging using vector adaptive weights smoothing Jörg Polzehl and Vladimir G. Spokoiny Weierstrass Institute for Applied Analysis and Stochastics, Germany Summary.
More informationSimultaneous Estimation of Response Fields and Impulse Response Functions PhD Thesis Proposal
Simultaneous Estimation of Response Fields and Impulse Response Functions PhD Thesis Proposal Erich Huang Carnegie Mellon University - Department of Statistics February 11, 2009 Abstract Relevant issues
More informationCocozza S., et al. : ALTERATIONS OF FUNCTIONAL CONNECTIVITY OF THE MOTOR CORTEX IN FABRY'S DISEASE: AN RS-FMRI STUDY
ALTERATIONS OF FUNCTIONAL CONNECTIVITY OF THE MOTOR CORTEX IN FABRY'S DISEASE: AN RS-FMRI STUDY SUPPLEMENTARY MATERIALS Sirio Cocozza, MD 1*, Antonio Pisani, MD, PhD 2, Gaia Olivo, MD 1, Francesco Saccà,
More informationINDEPENDENT COMPONENT ANALYSIS WITH FEATURE SELECTIVE FILTERING
INDEPENDENT COMPONENT ANALYSIS WITH FEATURE SELECTIVE FILTERING Yi-Ou Li 1, Tülay Adalı 1, and Vince D. Calhoun 2,3 1 Department of Computer Science and Electrical Engineering University of Maryland Baltimore
More informationUNSUPERVISED SPATIOTEMPORAL ANALYSIS OF FMRI DATA FOR MEASURING RELATIVE TIMINGS OF BRAIN RESPONSES. Santosh Bahadur Katwal.
UNSUPERVISED SPATIOTEMPORAL ANALYSIS OF FMRI DATA FOR MEASURING RELATIVE TIMINGS OF BRAIN RESPONSES By Santosh Bahadur Katwal Dissertation Submitted to the Faculty of the Graduate School of Vanderbilt
More informationA TEMPORAL FREQUENCY DESCRIPTION OF THE SPATIAL CORRELATION BETWEEN VOXELS IN FMRI DUE TO SPATIAL PROCESSING. Mary C. Kociuba
A TEMPORAL FREQUENCY DESCRIPTION OF THE SPATIAL CORRELATION BETWEEN VOXELS IN FMRI DUE TO SPATIAL PROCESSING by Mary C. Kociuba A Thesis Submitted to the Faculty of the Graduate School, Marquette University,
More informationA Functional Connectivity Inspired Approach to Non-Local fmri Analysis
A Functional Connectivity Inspired Approach to Non-Local fmri Analysis Anders Eklund, Mats Andersson and Hans Knutsson Linköping University Post Print N.B.: When citing this work, cite the original article.
More informationEffect of age and dementia on topology of brain functional networks. Paul McCarthy, Luba Benuskova, Liz Franz University of Otago, New Zealand
Effect of age and dementia on topology of brain functional networks Paul McCarthy, Luba Benuskova, Liz Franz University of Otago, New Zealand 1 Structural changes in aging brain Age-related changes in
More informationAdaptive statistical parametric mapping for fmri
Statistics and Its Interface Volume 3 (2010) 33 43 Adaptive statistical parametric mapping for fmri Ping Bai, Haipeng Shen, Jianhua Z Huang and Young K Truong, Brain activity is accompanied by changes
More informationMultiVariate Bayesian (MVB) decoding of brain images
MultiVariate Bayesian (MVB) decoding of brain images Alexa Morcom Edinburgh SPM course 2015 With thanks to J. Daunizeau, K. Brodersen for slides stimulus behaviour encoding of sensorial or cognitive state?
More informationLinear Models in Medical Imaging. John Kornak MI square February 22, 2011
Linear Models in Medical Imaging John Kornak MI square February 22, 2011 Acknowledgement / Disclaimer Many of the slides in this lecture have been adapted from slides available in talks available on the
More informationSection 9. Human Anatomy and Physiology
Section 9. Human Anatomy and Physiology 9.1 MR Neuroimaging 9.2 Electroencephalography Overview As stated throughout, electrophysiology is the key tool in current systems neuroscience. However, single-
More informationUnderstanding multivariate pattern analysis for neuroimaging applications
Understanding multivariate pattern analysis for neuroimaging applications Maria Giulia Preti Dimitri Van De Ville Medical Image Processing Lab, Institute of Bioengineering, Ecole Polytechnique Fédérale
More informationGLM for fmri data analysis Lab Exercise 1
GLM for fmri data analysis Lab Exercise 1 March 15, 2013 Medical Image Processing Lab Medical Image Processing Lab GLM for fmri data analysis Outline 1 Getting Started 2 AUDIO 1 st level Preprocessing
More information