Research Data Service Center Directorate of Research and Education. Clinical Datawarehouse USZ: Current Status and Outlook.
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1 Research Data Service Center Directorate of Research and Education Clinical Datawarehouse USZ: Current Status and Outlook Emmanuel Eschmann
2 Contents Overview of patient data at the University Hospital Zurich Accessibility of patient data for research Clinical reports and clinical decision support Current Status and Outlook Planned Cooperations Questions swiss ehealth summit
3 Patient Data at the University Hospital Zurich RNA seq BB BB 3 2 Biobank DNA A seq DNA seq PathoPro demographic data administrative records PACS RIS M/LAB medical reports prescriptions LEP ICD, «fever CHOP curve» diagnoses epa-ac hospindex interventions nursing reports EHR Perinat NANDA Tarmed EHR KISIM SAP ICU PDMS Radiance MICROS MOLIS swiss ehealth summit
4 Patient Data at the University Hospital Zurich RNA seq LEP ICD, CHOP PathoPro DNA seq DNA seq epa-ac hospindex NANDA Tarmed EHR Perinat EHR KISIM PACS SAP ICU PDMS RIS Radiance MICROS M/LAB MOLIS swiss ehealth summit
5 Patient Data at the University Hospital Zurich great potential for gaining new insights diversity of data heterogeneity of data change of data and change of data definition over time swiss ehealth summit
6 Accessibility of Clinical & Genomic Data for Research uniform structured data one single system Oracle Translational Research Center (TRC) swiss ehealth summit
7 Accessibility of Clinical & Genomic Data for Research UZH ETHZ Oracle Translational Research Center (TRC) swiss ehealth summit
8 Accessibility of Clinical & Genomic Data for Research Oracle Translational Research Center (TRC) TRC applications 3 rd party applications export interface to other systems personalized, pseudonymized, anonymized, or aggregated data swiss ehealth summit
9 DWH «Oracle Translational Research Center» swiss ehealth summit
10 Clinical reports and clinical decision support Oracle Translational Research Center (TRC) e.g. treatment recommendation based on analysis of clinical and genomic data Data to applications, exports, interfaces Clinical reports & decision support swiss ehealth summit
11 Summary of our services patient access to patient data clinical reports & decision support swiss ehealth summit
12 Current Status and Outlook Eval., POC, acquisition Installation Training Basic concepts UseCase 1: comprehensive view for tumor patients UseCase 2: patient recruitment UseCase 3 n swiss ehealth summit
13 Development of TRC based on UseCases UseCase 1: «comprehensive view for tumor patients» Output per tumor patient: clear compilation of relevant data source systems to be linked: Source system Administrative system (SAP) EHR (KISIM) Laboratory Informations systems (PathoPro, Sample Management, MOLIS) Sequencer Reference Files Data Demographic Data Clinical Diagnoses, Therapies, Drug Prescriptions Biomarker, histological Diagnoses Genomic Data Link Mutation -> Therapy swiss ehealth summit
14 Development of TRC based on UseCases UseCase 2: patient recruitment Identification of potential study patients initially exemplary for 3 studies extensible to any desired study multicenter study: expandable to other hospitals using TRC source systems to be linked: Source system Administrative system (SAP) EHR (KISIM) Data Demographic data Clinical Diagnoses, Therapies, Drug Prescriptions swiss ehealth summit
15 Planned Cooperations: Overview University Medicine Zurich Zurich - Basel Personalized Health Alliance DWH Services of the Swiss University Hosp. Swiss Personalized Health Network swiss ehealth summit
16 Planned Cooperations: University Medicine Zurich Research Data Service Center Lehrstuhl Biomedizininformatik Lehrstuhl Medizininformatik swiss ehealth summit
17 Planned Cooperations: Zurich - Basel Personalized Health Alliance swiss ehealth summit
18 Planned Cooperations: DWH Services of the Swiss University Hospitals? swiss ehealth summit
19 Planned Cooperations: SPHN Swiss Personalized Health Network (SPHN) swiss ehealth summit
20 Questions? Research Data Service Center Directorate of Research and Education swiss ehealth summit
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