Microlab 600 Series. Automated Intelligent Diluting and Dispensing

Transcription

1 Microlab 600 Series Automated Intelligent Diluting and Dispensing

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3 Table of Contents Introducing the Microlab Dual Syringe Diluter... 5 Single, Dual and Continuous Syringe Dispensers... 7 Standalone Syringe Pump for Custom Programming...9 Custom Program Syringe Pump See more on page 9 How Does It Work?...11 Syringe Pump Features Controller Features Controller Functionalities Wizards Quick Start Wizards Custom Methods Compliance and Security Features Current User: Admin Configuration Basic vs. Advanced Comparison See more on page 15 Utilities Log Off Favorites Printer Kit Universal Valves Bubble Free Prime Syringes Accessories About Hamilton Company Users Edit User Add User Export Users Import Users Configuration Compliance and Security Features See more on page 19 2

4 Introducing the Microlab 600 The Microlab 600 is a highly precise syringe pump with a touchscreen interface designed to quickly and easily dilute and dispense fluids. This positive displacement system provides better than 99% accuracy, independent of a liquid s viscosity, vapor pressure, and temperature. The inert fluid path minimizes sample carryover and is compatible with harsh chemicals. All labs can use the Microlab 600 Every laboratory has tasks too small to automate and too large to reliably accomplish by hand. The Microlab 600 is a semi-automated liquid handler designed specifically for these in-between applications that increases throughput and consistency while reducing cost and wasted buffer. Common industries using the product are: Forensics Environmental Analysis Mining Manufacturing

5 Benefits of the Microlab 600 The Microlab 600 offers labs a way to securely monitor processes and greatly increase efficiency. No more adjusting pipettes and recalculating dilutions. Quickly recall stored dispenses and dilutions with Favorites. Trigger the hand probe or tap the foot switch to actuate the syringe drives according to a predefined program. These are just some of the conveniences of the Microlab 600. Here are a few more: Reduce time preparing samples or dispensing reagents Minimize experimental variation from one user to the next Manage log files from any PC Comply with EPA, FDA GLP and GMP, CFR 21 Part 11 and ISO N.I.S.T. traceable calibration 4

6 Dual Syringe Diluter The Dual Syringe Diluter configuration uses two syringes to create up to a 1:50,000 dilution in a single step, drastically reducing preparation time and wasted buffer. The diluent washes the tubing between each sample, minimizing carryover for even the most sensitive techniques including: Atomic absorption (AA) Inductively coupled plasma spectroscopy (ICP) Liquid scintillation High performance liquid chromatography (HPLC) Gas chromatography (GC) Applications Forensics blood alcohol analysis and urinalysis Mining assay labs Metals detection Environmental analysis Water and soils testing Oil analysis preventative maintenance Alcohol testing beer and wine manufacturing Concentrated Sample 1/2 1/5 1/10 1/100 1/1,000 1/10,000 Dilution Diluent Sample Final Volume 1/2 500 µl 500 µl* 1000 µl 1/5 800 µl 200 µl* 1000 µl 1/ µl 100 µl* 1000 µl 1/ µl 10 µl 1000 µl 1/ µl 1 µl 1000 µl 1/ µl 0.1 µl 1000 µl This dilution series was performed using a 1000 µl diluent syringe on the left and a 10 µl sample syringe on the right. *These sample volumes were aspirated by the diluent syringe because the volume exceeded the capacity of the 10 µl sample syringe. 1,000 µl Final Volume Diluter Ordering Information Hamilton Part No. Fisher Scientific Cat. No. Description ML615-DIL ML625-DIL Dual Syringe Diluter with Basic Controller Dual Syringe Diluter with Advanced Controller The -DIL model ships with the Concorde hand probe, universal valves, fill/dispense tubing, accessory holder, country-specific power cord and the choice of two syringes. If syringes are not selected at the time of the order, 2.5 ml and 250 μl syringes are included.

7 See pages to learn how the diluter works. 6

8 Single, Dual and Continuous The Microlab 600 is able to dispense volumes from 100 nl to 50 ml. The Microlab 600 uses positive displacement syringes to accurately dispense volatile, viscous and dense liquids independent of atmospheric influences. The inert fluid path is compatible with harsh chemicals, making the Microlab 600 the most reliable and robust dispensing system available. Microlab 600 Dispensers Single Syringe Dispenser Dispense one liquid at a time Dual Syringe Dispenser Dispense two liquids at the same time Continuous Dispenser Minimize time between dispenses One syringe fills while the other dispenses Applications Sample spiking Titration Animal dosing (oral gavage) Reagent addition to chemical reactors Flow chemistry Manufacturing Mercury dispensing for light bulbs Ink cartridge filling Glue and epoxy dispensing Nasal therapeutics (viscous) Contact lenses Single Syringe Dispenser

9 Syringe Dispensers Continuous Dispenser Dispenser Ordering Information Hamilton Part No. Fisher Scientific Cat. No. Description Dual Syringe Dispenser ML610-DIS ML620-DIS ML615-DIS ML625-DIS ML615-CNT ML625-CNT Single Syringe Dispenser with Basic Controller Single Syringe Dispenser with Advanced Controller Dual Syringe Dispenser with Basic Controller Dual Syringe Dispenser with Advanced Controller Dual Syringe Continuous Dispenser with Basic Controller Dual Syringe Continuous Dispenser with Advanced Controller All dispensers ship complete with a Concorde hand probe (the dual dispenser uses the dual push button hand probe), universal valve(s), fill/dispense tubing, accessory holder, country-specific power cord, and the choice of syringes. If no syringe(s) are selected at the time of the order the DIS will ship with 1 ml syringe(s) and the CNT will ship with 10 ml syringes. See pages to learn how Single, Dual and Continuous Dispensers work. 8

10 Standalone Syringe Pump Take full command of your diluting and dispensing applications with the Microlab 600 standalone syringe pump. The standalone syringe pump allows you to custom program methods and deploy commands to any instrument on your network from anywhere in the world, giving you unparalleled control of your process. The standalone syringe pump comes with an Application Programming Interface (API) compatible with Windows computers running Microsoft.NET version 2.0 or higher. Sample programs written in LabVIEW, Visual Basic and Visual C# lay the groundwork for your own coding. This custom coding solution is the perfect solution for a variety of conditions including: Sequential applications when automated liquid diluting or dispensing is part of a series of actions or traveling along a conveyor belt Control room environments where applications are managed remotely Dispensing volatile or complicated liquids such as mercury, epoxy or radioactive materials as part of a manufacturing or testing process Settings that require a fully developed precision diluting or dispensing solution work in tandem with a larger system Liquid handling applications that require the integration of multiple electronic devices to accomplish a single task Any situation that could benefit from remote automation or custom programming

11 for Custom Programming Program your own methods in: Visual C# Visual Basic LabVIEW Standalone Pump Ordering Information Hamilton Part No. ML630 ML635 Fisher Scientific Cat. No Description Single Syringe Pump Dual Syringe Pump All standalone pumps ship complete with a universal valve(s), country-specific power cord, Custom Programmer kit, and choice of syringes. If no syringe(s) is selected at the time of the order 1 ml syringe(s) will be included automatically. 10

12 How Does It Work? The diagrams on these two pages illustrate the basic workflows of the four Microlab 600 models. Dual Syringe Diluter Method Step 1. Program the desired diluent and sample volumes. Step 2. Trigger the hand probe to fill the left syringe with diluent and aspirate sample into the hand probe with the right syringe. Step 3. Trigger the hand probe to dispense the sample and then diluent into a vial. Sample is isolated in the dispense tubing Sample is washed from the tubing by the diluent Diluent Diluent Concentrated Sample Diluted Sample Single Syringe Dispenser Method Step 1. Program the desired dispense volume. Step 2. Trigger the hand probe to fill the left syringe with solvent. Step 3. Trigger the hand probe to dispense the solvent into a vial. Solvent Solvent

13 Dual Syringe Dispenser Method Step 1. Program the desired dispense volume for solvent 1 and solvent 2. Step 2. Trigger the hand probe to fill the left and right syringes with solvents 1 and 2. Step 3. Trigger the hand probe to dispense the left and right syringe into the same or separate vials. Solvent 1 Solvent 2 Solvent 1 Solvent 2 Continuous Dispenser Method Step 1. Program the desired dispense volume. Step 2. Trigger the hand probe to fill a syringe with solvent. Step 3. Trigger the hand probe to dispense solvent from the full syringe and fill solvent into the empty syringe. One syringe is always filling while the other is dispensing. Solvent Solvent Solvent 12

14 Syringe Pump Features The Microlab 600 is available as a single or dual syringe system. The high torque, precision stepper motors provide unsurpassed positional accuracy across the full range of Hamilton syringes from 10 µl to 50 ml. The instrument communicates with the controller or a corporate network via an Ethernet port. 1 1 Fanless heat vent 2 24 volt power input 3 CAN daisy chain input/output 4 RS-232 console port 5 6 Power over Ethernet (PoE) TTL input/output Single and Dual Syringe Pump Specifications Accuracy +/- 1% Precision +/- 0.2% Flow rate Syringe resolution Compatible syringes Fluid path Communication type Communication protocol Pump memory Calibration Certifications µl/second (depending on the syringe that is selected) 0.002% of the nominal syringe volume 10, 25, 50, 100, 250, 500 µl, 1, 2.5, 5, 10, 25, and 50 ml Borosilicate, PTFE, CTFE Ethernet, 10/100 BASE-T.NET 2.0 Application Programming Interface (API) One method stored in non volatile memory Factory tested and traceable to N.I.S.T. standards CE, CSA Power rating 24 VDC, 2.5 A 1 2 High torque valve motors Precision syringe drives with 48,000 step resolution over 60 mm 3 4 Lighted power and prime buttons Independent left and right trigger ports Dimensions Weight 7 x 5.5 x 10.5 inch (177.8 x x mm) 13 lbs (5.9 kg)

15 Controller Features The Microlab 600 controller features a large, easy-to-use touchscreen. Dilutions, dispenses, titrations and more display in real time at the touch of a button. 2 1 Controller Specifications 1 Touchscreen Screen size 5.7 inch (15 cm diagonal) Screen tilts for best view angle Expansion slot Ethernet USB printer port Screen resolution Tilt positions Mounting options Program memory 640(W) x 480(H) pixels 5 positions from 90 to flat On top of the syringe pump, bench top, or wall mount 2 GB (with Advanced upgrade) Communication type Ethernet, 10/100 BASE-T A hardware key goes into the expansion slot that unlocks advanced functionality such as wizards, custom methods and enhanced security options, and also provides an upgrade path to the most current firmware. See next page for more information. Power rating Dimensions Weight 24 VDC, 2.5 A 2.25 x 6.5 x 7 inch (57.2 x x mm) in down position 1.9 lbs (0.86 kg) 14

16 Controller Functionalities Hamilton conducted human factor studies to create a clear and understandable system that is communicated through a straightforward user interface. Each screen was thoughtfully designed to simplify the flow of each process and maximize its ease of use. Basic Controller The Basic Microlab 600 controller quickly performs standard dilutions and dispensing using a Quick Start screen. Advanced Controller The Advanced controller contains a significant number of additional features and allows users to create methods using air gaps, washing repetitive dispensing and more. For users with the Basic controller that would like to upgrade, it can be easily converted to the Advanced using a simple software kit. Basic & Advanced Functionality Comparison Features Basic Advanced Quick Start Screen Prime the instrument, program the dispense volume and start dispensing. Graphical Pump Status Animations of the fluid path display the current and future state of the syringe pump. Adaptive Dispense Control Adjust dispense volumes in mid-process and the instrument will recalculate the remaining dispenses and proper time to refill. Configuration Guide Step-by-step help to set up the instrument. Wizards Dedicated wizards for aliquot dispensing, serial dispensing, dilution, pipetting and titration. Favorites Menu Quickly access frequently used methods. Custom Method Programming Create custom applications not covered by a wizard. Enhanced Security Meet CFR 21 Part 11 and FDA GMP/GLP requirements using custom security options. Method Storage Create and run more than 1,000 methods on a single controller. Log File Creation Create and store files on a memory card, or permanently on a PC using LyncStore, to meet hardcopy archive requirements. Language Options Operate the instrument in 10 languages. Software Upgrades Download software updates and receive exciting new features.

17 Basic Quick Start Quick Start Ready Graphical status of the current valve and syringe position Ready 2500 µl Press this button to adjust the dispense volume at any time 1000 µl Toggle the Auto Refill button on and off Refill OFF 2.5 ml µl Configuration Run Advanced Software - Main Menu Edit and run custom methods Quickly program applications Quick Start Wizards Wizards simplify set up and common tasks Custom Methods Configure the pump hardware and security features Configuration The current user displays Download a method, custom prime and check diagnostics Utilities Current User: Admin Log Off Favorites Easily recall favorite methods Language Selector Menu Language Selector English Français Italiano Português Español Deutsch System The Microlab 600 operates in 10 languages: English, Spanish, German, French, Italian, Portuguese, Korean, Japanese, Traditional and Simplified Chinese Do not show this dialog again. 16

18 Wizards Wizards are offered in Advanced Microlab 600 products. They provide step-by-step set up guidance and help perform common dispensing and diluting applications. Frequently used methods can be saved as Favorites for one touch activation. Below are brief descriptions and diagrams of the application wizards. Aliquot Dispense Wizard Serial Dispense Wizard Repetitively dispense aliquots of the same volume at the press of a button. Repetitively dispense aliquots of differing volumes at the press of a button. Aliquot Dispense Wizard Aliquot Dispense Aliquot Aliquot Wizard Dispense Dispense Wizard Wizard Aliquot Dispense Wizard Aliquot Dispense Wizard Dispense Wizard AliquotAliquot Dispense Wizard Single Syringe Aliquot Single Syringe Aliquot Single Syringe SingleAliquot Syringe Aliquot 2 Dispense through hand probe 3 Dispense 4 Dispense Dual Syringe Dual Syringe Aliquot Dual Syringe DualAliquot Syringe Aliquot Aliquot Dual Syringe Aliquot DualAliquot Syringe Aliquot Dual Syringe Dual Syringe Aliquot 2 Dispense through hand probe 1 Fill from reservoir 3 Dispense 4 Dispense 1 Fill from reservoir Single Syringe Single Syringe Aliquot Single Syringe Aliquot Single Syringe Aliquot Single Syringe Aliquot Aliquot or Serial Dispense Dual Syringe Aliquot or Serial Dispense Tritration Wizard Slowly add liquid to another liquid until an endpoint is reached. An example of this application is adding acid or base to ph a buffer. Titration Titration Wizard Titration Wizard Wizard Simple Titration Simple Simple Titration Titration 1 Fill from reservoirs Tritration 2 Dispense the initial volume 3 Dispense the step volume A large initial volume is dispensed to get close to the endpoint. Then a smaller step volume is dispensed until the endpoint is reached. Pipette Wizard Simulate a manual pipette used to transfer liquid from one vessel to the next. Pipette Pipette Wizard Pipette Wizard 1 Aspirate samplesimple Dispense Simple Dispense into the hand probe 2 Dispense sample from the hand probe

19 Dilution Wizard Accurately dilute concentrated samples with diluent over a wide range of dilution ratios. Single Syringe Dilution Dilution Wizard Dilution Wizard Dilution Wizard 1 Fill with diluent from the reservoir 2 Aspirate sample into the hand probe Single Syringe Dilution Single Syringe Dilution Single Syringe Dilution 3 Dispense sample and diluent DilutionDilution Wizard Wizard Dilution Wizard Dual Syringe Dilution 2 Aspirate sample 1 Fill with diluent Simple Dilution Simple Dilution Simple Dilution from the reservoir into the hand probe 3 Dispense sample and diluent Icon Key Valve Reservoir Serial Dilution (programmed) Serial Serial Serial Dilution Dilution Dilution Dilution (Programmed) (Programmed) (Programmed) 2(Programmed) 1Serial 3 1/50 1/10 1/25 Hand Probe 4 1/100 Syringe Repeat the steps for single or dual dilution with varying dilution ratios and the same final volume. Color Guide Reagent 1 / System Fluid Reagent 2 Sample Serial Dilution (tube to tube) 2 1/10 1 Sample Serial Dilution (Tube to Tube) 3 1/100 Diluted Sample Standard Titration Endpoint 4 1/1000 Diluted Sample + Standard Repeat the steps for single or dual dilution and use the resulting dilution as the sample for the next dilution. Multi Sample Dilution (or Internal Standard Addition) Multi Dilution (or Internal Standard Addition) 1 FillSample with diluent Multi Sample (or Dilution 2(orAspirate Internal sample Standard Addition) 3 Aspirate standard Multi Sample Dilution Standard Addition) Multi Internal Sample Dilution (or Internal Standard Addition) from the reservoir into the hand probe into the hand probe 4 Dispense standard, sample, and diluent 18

20 Compliance and Security Features The Advanced Microlab 600 comes equipped with a comprehensive compliance package that provides a variety of security protections and simplifies adherence to CFR 21 Part 11 and FDA GLP/GMP regulations. Highlights include the ability to administer user accounts and passwords, enable activity traceability and manage log files on a PC using the LyncStore application. Edit User First Name Setting User ID First Name Last Name User Account Disabled Create and Edit User Accounts Edit the Pump Configuration John Value tech1 John Smith Yes No Yes The package is designed for: FDA GXP regulated facilities Pharmaceutical manufacturing Clinical testing QA/QC laboratories Contract manufacturers User List Each user account can be customized to only allow certain access or permissions. Enhanced Security Features Specially designed to meet the needs of regulated labs or labs with strict security protocols Create user accounts, define roles, modify permissions and provide password protection Logins provide total traceability by tracking all user activity such as running or editing methods, configurations and wizards Advanced Log Management Create and view files compliant with CFR 21 Part 11 Electronic signatures ensure user accountability Store logs on a 2 GB SD card or permanently via LyncStore Varying security levels allow labs to customize the protection of their processes Configure security settings from one convenient screen. LyncStore Software PC-based management system Simplifies log file maintenance for multiple instruments View, archive, sort, filter and compare files by users or other variables Consolidate log files from multiple controllers to one database Print log files to any printer connected to the PC LyncStore allows users to manage log files generated on multiple diluters and dispensers.

21 Printer Kit The compliance package works with the new Advanced Microlab 600 printer kit. The kit is an accessory item that satisfies regulatory hardcopy requirements by printing log files directly from the device. Conveniently print log files from the controller with the touch of a button Satisfies requirements for closed-circle reporting direct from the device Compatible with all Advanced Microlab 600 devices running current software Includes printer, power source, adapter and cable Uses standard, non-thermal 8.5 x 11 inch and A4 paper suitable for archiving Printer Kit Ordering Information Hamilton Part No. Fisher Scientific Cat. No. Description Printer Kit 20

22 Universal Valves Innovative fluid logic allows the same universal valve to be used in all Microlab 600 diluting and dispensing applications. Interchange the valve plugs and tubing to achieve the following configurations in a matter of minutes. Valve Plumbing Based on Instrument Configuration Dual Syringe Diluter Single Syringe Dispenser Fill Tubing Fill Tubing Plug Plug Plug Cross Tube Dispense Tubing Dispense Tubing Dual Syringe Dispenser Fill Tubing Fill Tubing Continuous Dispenser Fill Tubing Fill Tubing Plug Cross Tube Dispense Tubing Plug Continuous Tubing Dispense Tubing

23 Bubble Free Prime Syringes Patented conical tip extends through the threaded termination and into the valve For any syringe pump, the key to achieving the most accurate dispenses is eliminating all air from the fluid path. Traditional syringes trap approximately 50 µl of air between the tip of the syringe and the valve. For small syringes, this trapped air is the last to leave the syringe and the first to be drawn back in, making them difficult if not impossible to prime. The Bubble Free Prime syringe has a conical plunger tip that extends through the threaded termination and into the valve. This unique design expels the air from the syringe and valve decreasing the number of priming cycles required. Bubble Free Prime vs. Standard Syringes Bubble Free Prime Syringe Bubble Free Prime syringes eliminate air from the fluid path Trapped Air Syringe Plunger Standard Syringe Traditional Luer Lock syringes trap approximately 50 µl of air, making small syringes nearly impossible to prime 22

24 Accessories Hand Probes, Foot Switch, and Disposable Tips Concorde CT Hand Probe (Standard with the Single Syringe Dispenser, Dual Syringe Diluter, and Continuous Dispenser) Disposable Tip Hand Probe 1 35 µl or µl Luer Lock Conversion Kit (P/N ) Dual Push Button Hand Probe (Standard with the Dual Syringe Dispenser) Large Volume Disposable Tip Hand Probe Hand Probes, Foot Switch, and Disposable Tips Hamilton Part No. Fisher Scientific Cat. No. Description Disposable Tips Foot Switch Concorde CT Hand Probe Dual Push Button Hand Probe Disposable Tip Hand Probe 1 35 μl Disposable Tip Hand Probe μl μl Disposable Tips Bulk μl Disposable Tips Racked (5 racks of 96) Large Volume Disposable Tip Hand Probe (5 ml) ml Disposable Tips (250/pk) Foot Switch

25 Syringes and Power Supplies Syringes Hamilton Part No. Fisher Scientific Cat. No. Syringe Size Optimal Range μl 1 10 μl μl μl μl 5 50 μl μl μl μl μl μl μl ml 100 μl 1.0 ml ml 250 μl 2.5 ml ml 500 μl 5.0 ml ml ml ml ml ml ml Selecting a Syringe: Select the smallest syringe with a maximum volume that is greater than the largest volume to be dispensed. Ideally the smallest volume to be dispensed should fall within the optimal ranges listed above. The Microlab 600 can dispense volumes below the optimal range but there will be some impact on accuracy and precision. Contact a Hamilton sales representative for additional assistance. Syringe Power Supply & Power Cords Hamilton Part No. Description Power Supply Universal ( VAC) Hamilton Part No. Fisher Scientific Cat. No. Fisher Scientific Cat. No. Description Switzerland Continental Europe, Russia, Schuko Australia, New Zealand, Argentina, China UK, Ireland, Malaysia, Middle East Diagram of Plug Power Cord Japan USA, Canada, Mexico, Central America, Brazil Power Supply 24

26 Valves, Tubing, Upgrade Kits and Miscellaneous Accessories Universal Valve & Accessories Hamilton Part No. Fisher Scientific Cat. No. Valve Assembly Description Left Valve Assembly Right Valve Assembly Valve Cross Tube Assembly Valve Plugs Left Valve Valve Plugs Right Valve Cross Tube PTFE Tubing Assemblies Hamilton Part No. Fisher Scientific Cat. No. Gauge Type Length Internal Volume Fill Tubing 48" (1219 mm) 1.15 ml Dispense Tubing 54" (1372 mm) 1.29 ml Fill Tubing Custom Length 0.94 µl/mm Dispense Tubing Custom Length 0.94 µl/mm Fill Tubing 48" (1219 mm) 4.57 ml Dispense Tubing 54" (1372 mm) 5.15 ml Fill Tubing Custom Length 3.75 µl/mm Dispense Tubing Custom Length 3.75 µl/mm Continuous Fill Tubing 0.94 µl/mm Continuous Fill Tubing 3.75 µl/mm Fill & Dispense Tubing (Dispense tubing has tapered end) Upgrade Kit Hamilton Part No. Fisher Scientific Cat. No. Upgrade Kit Includes Basic to Advanced Controller Upgrade Kit Custom Programmer Kit (Compatible with Microsoft.NET 2.0 and higher) Advanced manual, 2 GB SD card, SD to USB converter and programmer software CD Programmer software CD with manual, Application Programming Interface and example LabVIEW, Visual C# and Visual Basic programs Software CD & SD Card Misc. Accessories Hamilton Part No. Fisher Scientific Cat. No. Description Tubing Clips (5/pk) Accessory Holder & Tubing Wire Stand Accessory Holder & Wire Stand Tubing Clips

27 About Hamilton Company Hamilton Company is a global enterprise with headquarters in Reno, Nevada, Hopkinton, Massachusetts, and Bonaduz, Switzerland and subsidiary offices throughout the world. We are an industry leader in the design and manufacture of liquid handling, process analytics, robotics and automated storage solutions. For more than 50 years, Hamilton has been satisfying customer needs by combining quality materials with skilled workmanship to ensure the highest level of performance. Hamilton s lifelong commitment to precision and quality has earned us global ISO 9001 Certification. Founded on the technology of analytical Microliter and Gastight syringes, Hamilton has a broad offering of laboratory products including manual and semiautomated precision fluid measuring instruments, chromatography products, process sensors, laboratory electrodes, pipettes and more. Top innovations from these lines include Arc ph, DO and conductivity intelligent sensors, the BioLevitator, Microlab 600 diluters/dispensers and the DeCapper. A pioneer in liquid handling equipment and laboratory automation technology, Hamilton Robotics is known for advancing life science and biotechnology industries through reliability, performance and flexibility. Hamilton continues to be the market leader with patented technologies such as Compression-induced O-Ring Expansion (CO-RE), Total Aspiration and Dispensing Monitoring (TADM) and Anti Droplet Control (ADC). Hamilton s feature platform, Microlab STAR, is the highest selling automated pipetting platform for several years running, while Microlab NIMBUS is the first in class of compact, high-speed personalized pipetting workstations. The Hamilton Storage Technologies division offers comprehensive ultra-low temperature automated sample management systems for a broad array of life science processes. Its line of biobanking, compound storage and consumable solutions consists of products such as BiOS, SAM and ASM, designed for sample integrity, flexibility, and reliability. Hamilton Company is focused on blending invention and accuracy to deliver customers unparalleled products. 26

28 Lit. No. L10062_Fisher Scientific Hamilton Company 2/2012 4,000 Printed in U.S.A. BN