Title: Management of Hypertension and Multiple Risk Factors to Enhance Cardiovascular Health - A Feasibility Study in Singapore Polyclinics

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1 Author s response to reviews Title: Management of Hypertension and Multiple Risk Factors to Enhance Cardiovascular Health - A Feasibility Study in Singapore Polyclinics Authors: Tazeen Jafar (tazeen.jafar@duke-nus.edu.sg) Ngiap Tan (tan.ngiap.chuan@singhealth.com.sg) John Allen (john.allen@duke-nus.edu.sg) Shreyasee Pradhan (shreyasee.pradhan@duke-nus.edu.sg) Paul Goh (paul.goh@singhealth.com.sg) Saeideh Tavajoh (saeideh.tavajoh@duke-nus.edu.sg) Fong Keng (fong.mew.keng@singhealth.com.sg) Jason Chan (jason.chan.m.h@singhealth.com.sg) Version: 2 Date: 23 Jun 2016 Author s response to reviews: Dear Editor-in-chief, We appreciate your thorough review of our manuscript (ref BHSR-D R1) entitled Management of Hypertension and Multiple Risk Factors to Enhance Cardiovascular Health - A Feasibility Study in Singapore Polyclinics has been potentially accepted for publication by BMC Health Services Research. We thank the reviewers for their valuable feedback. We have incorporated all amendments in the revised manuscript Enclosed is the revised original article, as approved by the co-authors, for consideration in your journal. Below is a summary of our point by point responses (in red color) to the comments:

2 1. Please include the registration date of the trial with the other trial information, and also state if it was retrospectively registered (registered after the 1st participant was recruited). Thank you for the suggestion. ClinicalTrials.gov registration was dated December 28, 2014 that is before the 1st participant was recruited in September Please also update the abstract on the submission system to include the trial registration details. Noted with thanks. Done. 2. We request that all supplementary information be uploaded as additional files, so please upload the appendices included in the manuscript as separate supplementary files. We uploaded appendices as in supplementary document listed in the file inventory 3. Along with submitting supplementary files, we would appreciate if you added a Œ Supplementary files¹ section after References that lists the following information for these files: File name, Title of data, Description of data. Thank you for your suggestion. We inserted the information for Supplementary files 4. We require all sections listed under Declarations in our submission guidelines ( be provided in the manuscript, so please add Œ Consent for publication¹ to the declarations. You can simply state ³Not applicable² in this section. Noted and done. 5. Please clarify the type of consent received from participants (written or verbal).

3 It was written informed consent, and has been mentioned clearly in the manuscript. 6. Please remove the figure titles/captions from within the figure files. These files should contain the image graphic only. Please place any titles/captions as text after the References. We have placed caption after the References 7. Upon uploading your revisions, please remove any tracked changes or highlighting and include only a single clean copy of the manuscript. Noted with thanksdear Editor-in-chief, We appreciate your thorough review of our manuscript (ref BHSR-D R1) entitled Management of Hypertension and Multiple Risk Factors to Enhance Cardiovascular Health - A Feasibility Study in Singapore Polyclinics has been potentially accepted for publication by BMC Health Services Research. We thank the reviewers for their valuable feedback. We have incorporated all amendments in the revised manuscript Enclosed is the revised original article, as approved by the co-authors, for consideration in your journal. Below is a summary of our point by point responses (in red color) to the comments: 1. Please include the registration date of the trial with the other trial information, and also state if it was retrospectively registered (registered after the 1st participant was recruited). Thank you for the suggestion. ClinicalTrials.gov registration was dated December 28, 2014 that is before the 1st participant was recruited in September Please also update the abstract on the submission system to include the trial registration details.

4 Noted with thanks. Done. 2. We request that all supplementary information be uploaded as additional files, so please upload the appendices included in the manuscript as separate supplementary files. We uploaded appendices as in supplementary document listed in the file inventory 3. Along with submitting supplementary files, we would appreciate if you added a Œ Supplementary files¹ section after References that lists the following information for these files: File name, Title of data, Description of data. Thank you for your suggestion. We inserted the information for Supplementary files 4. We require all sections listed under Declarations in our submission guidelines ( be provided in the manuscript, so please add Œ Consent for publication¹ to the declarations. You can simply state ³Not applicable² in this section. Noted and done. 5. Please clarify the type of consent received from participants (written or verbal). It was written informed consent, and has been mentioned clearly in the manuscript. 6. Please remove the figure titles/captions from within the figure files. These files should contain the image graphic only. Please place any titles/captions as text after the References. We have placed caption after the References

5 7. Upon uploading your revisions, please remove any tracked changes or highlighting and include only a single clean copy of the manuscript. Noted with thanks

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