EXAMPLES OF UTILISING 3D TECHNOLOGIES FOR CLINICAL USE

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1 3D LIFEPRINTS EXAMPLES OF UTILISING 3D TECHNOLOGIES FOR CLINICAL USE

2 CLINICAL USE 1: PRE & INTRA SURGICAL PLANNING 3D PRINT MODEL TYPE: SPINAL KYPHOSCOLIOSIS TRI-PLANAR CT SCAN SLS 3D PRINTER USING STERILISABLE POLYAMIDE 3D FILAMENT A 3D printed spinal model was used to assist with a complex procedure to rectify a congenital spinal kyphoscoliosis on an eight-year-old patient. The model was used by the surgical team for pre-operative planning purposes, and subsequently sterilized using an autoclave container and brought into the operating theatre to be used for guidance. Lead surgeon Neil Davidson remarked: The model was invaluable for use by the surgical team to undertake this complex procedure. It was useful both preoperatively and intraoperatively - the surgery would have been much more complicated and difficult without the model in theatre. Without the model, the surgical team would have had a higher chance of needing to carry out an anterior approach to the spine which would have increased time in the theatre and the surgical risks of complications to the patient.

3 CLINICAL USE 2: PRE & INTRA SURGICAL PLANNING 3D PRINT MODEL TYPE: CRANIAL DEFORMITY SKULL TRI-PLANAR CT SCAN FDM 3D PRINTER USING RIGID PLASTIC 3D MATERIAL This 3D model was created for a neurosurgeon to help visualise the child s craniosynostosis where the bones of the skull had closed prematurely. The planning done on the model prior to surgery allowed the team to pre-plan their cutting on the model. This would normally be done intraoperatively increasing the surgery time and therefore overall operational costs.

4 CLINICAL USE 3: PRE SURGICAL PLANNING 3D PRINT MODEL TYPE: HEART CARDIOMYOPATHY 3D PRINT MODEL TYPE: HEART CARDIOMYOPATHY LIVERPOOL CHEST & HEART HOSPITAL, LIVERPOOL, ENGLAND CONTRASTED TRI-PLANAR CT SCAN, ANGIOGRAM FDM 3D PRINTER, FLEXIBLE PLASTIC 3D MATERIAL A 3D printed model was created to provide surgeon Robert Cooper and his team with information on the heart wall thickness in both the relaxed and the contracted stages of the heartbeat for preparation for an alcohol septal ablation. A study consisting of nine further models has been commissioned based on the success of this model. Patients are currently being identified to participate in the study.

5 CLINICAL USE 4: PRE SURGICAL PLANNING 3D PRINT MODEL TYPE: HIP OSTEOTOMY SOUTHAMPTON HOSPITAL, SOUTHAMPTON, ENGLAND TRI-PLANAR CT SCAN FDM PRINTER An acetabulum and femur head were 3D printed in white ABS to assist with a complex bilateral pelvic procedure. Lead surgeon Alex Aarvold remarked: With a difficult case such as this one that needed a slightly bespoke pelvic osteotomy, the benefit was more in the surgical planning than in actual operative time saved. In this respect it was fantastic, and we could see what we needed to do very quickly on the model, which was not nearly so clear on the CT images. We could also trial the planned osteotomy on the model so we had more confidence in the surgical plan..

6 CLINICAL USE 5: PRE SURGICAL PLANNING 3D PRINT MODEL TYPE: BLOCKED PULMONARY ARTERY TRI-PLANAR CT SCAN FDM 3D PRINTER USING RIGID PLASTIC 3D MATERIAL A number of 3D printed models of a one-year-old patient s heart were created as pre-surgical assessment tools for the surgical team in planning an operation on a heart that had a blocked pulmonary artery. The pre-surgical planning process was enhanced by using the 3D models which led to time savings in the operating theatre and an improved patient outcome. Lead surgeon Rafael Guerrero said: This is a great use of 3D printing as it shows me exactly what we needed to see. The initial 3D model was used to plan for the successful provision of a pulmonary artery banding to rectify multiple holes in the baby s heart. The subsequent 3D print showed that the right ventricle and the left ventricle were full of blood and that communication was occurring between the right side and the left ventricle. The patient s multiple Ventricular Septal Defects have decreased in size from the first operation. The model is tremendously helpful as it shows we do not need to do any more surgery inside the small holes. So it is a great model.

7 CLINICAL USE 6: PRE SURGICAL PLANNING / TRAINING 3D PRINT MODEL TYPE: 3D VIRTUAL REALITY VIRTUAL ENGINEERING CENTRE, LIVERPOOL UNIVERSITY, ENGLAND MRI SCAN FDM 3D PRINTER USING FLEXIBLE PLASTIC 3D MATERIAL AND VR GOGGLES This product allows a surgeon to manipulate a handheld and patient specific 3D print of an organ, such as a heart, to virtually navigate its internal structure and external surroundings using a virtual reality headset. The Virtual Engineering Centre commented: We are developing an exciting collaboration with 3D LifePrints, bringing together the specialist expertise of both organisations in 3D printing and immersive virtual reality to support the medical sector. We are looking forward to forging future developments with such an innovative organisation.

8 CLINICAL USE 7: SURGICAL TRAINING 3D PRINT MODEL TYPE: VEIN SUTURING ROYAL SICK CHILDREN S HOSPITAL, EDINBURGH, SCOTLAND 3D MODELLED IN-HOUSE BY 3D LIFEPRINTS FDM 3D PRINTER USING FLEXIBLE 3D MATERIALS A 3D model was printed to provide surgeons with a method of practicing the suturing of veins during medical training. Feedback from the surgeon was positive in that the 3D printed model provided a high level of realism for medical training which exceeded current training materials.

9 CLINICAL USE 8: SURGICAL TRAINING 3D PRINT MODEL TYPE: BRAIN MRI SCAN SILICONE 3D PRINTER This 3D model of part of an adult brain was created to show that silicone 3D printing can provide a realistic replica for soft tissue and organs. The silicone is printed in a range of colours and densities and it is intended to be used in medical training for operations such as Lobe resection and Lesionectomy. Feedback from the surgeons at Alder Hey was extremely positive especially concerning the realism of the model and potential future use of medical training purposes. It is proposed to combine the silicone brain with a skull printed in polyamide to provide a high fidelity model for surgical simulation.

10 CLINICAL USE 9: SURGICAL TRAINING 3D PRINT MODEL TYPE: PERCUTANEOUS ENDOSCOPIC GASTROSTOMY MRI SCAN SILICONE 3D PRINTER A soft stomach 3D model was created to provide surgeons with a realistic simulator for PEG insertion training. This training model will be used by theatre staff to practice stomach tube insertions prior to undertaking the procedure on patients. Upwards of 180 of these operations are carried out every year at Alder Hey hospital alone. Feedback from the surgeon was positive in that the 3D printed training model was superior to any products previously available to the surgical team particularly in texture and density of tissue. The training model can also be easily reprinted to include specific anatomical features for particular patients.

11 CLINICAL USE 10: SURGICAL SIMULATION 3D PRINT MODEL TYPE: FOOT DEFORMITY MAIDSTONE HOSPITAL, KENT, ENGLAND TRI-PLANAR CT SCAN SLS PRINTER AND FDM PRINTER USING PLASTICS AND WOODFILL 3D models showing congenital bone deformities were supplied to surgeon Marcos Katchburian so that the surgery could be better planned and simulated on the models prior to the operation. 3D printing in woodfill (which is a mix of PLA and wood fibers) allows a surgeon to cut the model which responds in a manner similar to the cutting of bone. Simulation enables greater pre-operative planning thereby reducing the amount of time the surgeons spend in theatre and improves their understanding and accuracy.

12 CLINICAL USE 11: SURGICAL SIMULATION 3D PRINT MODEL TYPE: KIDNEYS FOR PARTIAL NEPHRECTOMY TRAINING MRI SCAN SILICONE 3D PRINTER A kidney with a tumor was dual-colour printed in soft silicone with varying densities across sections of the model for surgical training use. A simulated partial nephrectomy was carried out on the model, showing potential to simulate surgeries and thereby improve surgical skills. Feedback from the surgeon was positive in that the 3D model provided an accurate representation with high fidelity for simulating the removal of the tumour.

13 CLINICAL USE 12: SURGICAL SIMULATION 3D PRINT MODEL TYPE: SKULLS FOR CRANIOTOMY TRI-PLANAR CT SCAN, BLACK BONE MRI IMAGING SLS 3D PRINTER USING POLYAMIDE 3D MATERIAL, FDM 3D PRINTER USING PLA AND WOODFILL A number of skulls were 3D printed in a variety of materials to determine the best material for Craniofacial drilling simulation. Feedback from the neurosurgeon stated that the polyamide responded best to the cutting methods in simulating skull bone cutting. The woodfill was found to be an accurate representation of young children s cartilaginous skulls and had a similar pliability when drilled.

14 CLINICAL USE 13: MEDICAL RESEARCH 3D PRINT MODEL TYPE: COMPLEX ANKLE FRACTURES TRI-PLANAR CT SCAN FDM 3D PRINTER USING RIGID PLASTIC 3D MATERIAL A number of 3D models were created for a variety of complex triplanar ankle fractures. These models were used by the surgeon in workshops, where the model was separated along the fracture line so that the participating clinicians could see the exact topography of the break and understand how it could be treated. The results of the workshops were incredibly positive with clinicians confirming that the models improved their understanding the issues, as well as greatly improving their ability to describe the 3D configuration of the break for teaching purposes. Surgeon Roger Walton commented: I believe the use of a 3D model could improve pre-operative planning and produce novel operative strategies for new cases.

15 CLINICAL USE 14 : MEDICAL RESEARCH 3D PRINT MODEL TYPE: RABBIT HEART ATRIAL WALL JOHN MOORES UNIVERSITY, LIVERPOOL, ENGLAND MICRO CT SCANNER MULTI-JETTING 3D PRINTER In this study a rabbit heart was micro CT scanned post-mortem with the aim of identifying and isolating specific regions of the heart in a 3D space for further understanding of the heart s electrical conduction system. Feedback from Professor Robert Stephenson: Working with 3D LifePrints we have produced high resolution 3D prints of the heart of unprecedented quality and detail. Generated from high resolution micro-ct data sets such prints have brought our virtual data to life, and serve to improve our understanding of the 3D micro-anatomy of the heart. A further series of 3D printed models based upon human hearts is planned which will increase the scope of this project.

16 CLINICAL USE 15: MEDICAL RESEARCH 3D PRINT MODEL TYPE: HIP DYSPLASIA TRI-PLANAR CT SCAN FDM 3D PRINTER USING RIGID PLASTIC 3D MATERIAL A series of 3D printed models were created to investigate the following Can 3D printing replace an arthrogram for hip imaging? Reconstructive surgery is frequently employed to improve the congruency of the hip, to prolong or obviate the time-to-arthroplasty. Surgical decisions regarding reconstructive surgery can be challenging. An arthrogram is the most dynamic investigation, however only offers two-dimensional imaging and necessitates a general anaesthetic and time in the operating theatre. 3D printing offered an opportunity to produce bespoke dynamic models of diseased hips, which enabled the surgeon to gain a greater insight into the surgery required. It was useful in the process of obtaining patient consent, enabling surgeons to perform surgery on the printed model preoperatively as a trial-run or when training trainee surgeons. By testing different materials, the models enabled surgeons to test optimal osteotomy positions (cuts in the bone), and enabled them to reliably template (size) the materials required for the procedure.

17 CLINICAL USE 16: MEDICAL EDUCATION 3D PRINT MODEL TYPE: RESPIRATORY TRAINING TRI-PLANAR CT SCAN FDM 3D PRINTER USING PLASTIC RIGID MATERIAL These 3D models were created as training aids for parents of patients and NHS staff on the positioning and forming of a stoma in the esophagus in medical emergency situations. Feedback from the medical education team within the hospital was positive: The detail level was more than sufficient. It allowed my trainees to visualise the structure and better understand the techniques used, and why they are performed that way. Further design iterations are planned including a flexible and pierceable esophagus that will provide greater fidelity.

18 CLINICAL USE 17: MEDICAL ARCHIVING 3D PRINT MODEL TYPE: DENTAL ARCHIVING 3D SCAN FDM 3D PRINTER USING PLASTIC RIGID MATERIAL, ARTEC EVA HANDHELD 3D SCANNER The 3D models were created to provide an exact replica of the plaster of Paris dental moulds currently employed by the hospital. Once the existing dental moulds have been scanned the data can be stored electronically which eliminates the need to keep a physical mould in archives. The projected outcome would remove the need to store the plaster of Paris moulds as the virtual mould could be scanned and stored on a cloud based platform and retrieved and 3D printed when necessary. A further project would be to eliminate the need for a plaster of Paris mould by directly scanning the patient s teeth.

19 CLINICAL USE 18: IMPROVING DOCTOR-PATIENT COMMUNICATIONS 3D PRINT MODEL TYPE: SCOLIOTIC SPINE TRI-PLANAR CT SCAN FDM 3D PRINTER USING RIGID PLASTIC 3D MATERIAL This 3D model was created to aid the surgeon in discussions with the patient s family about their child s spinal deformity. From Dr. Neil Davidson: I think the reproduction is excellent and will benefit the patient from both the clinical perspective, and the family s understanding of the nature of her pathology. I used the 3D reconstruction to help the family understand exactly the nature of the deformity. At the end of the consultation the patient s mother admitted that it was the first time she really understood the complexity of the deformity.

20 CLINICAL USE 19: PATIENT CARE 3D PRINT MODEL TYPE: SCOLIOSIS SPINE EOS SCANNER EOS SCANNER, FDM 3D PRINTER USING RIGID PLASTIC 3D MATERIAL This 3D printed model was produced from a stereo radiographic image (i.e an x-ray) of a full pelvis and scoliotic spine. The EOS scanner creates 3D images from x-ray alone, using software algorithms. Due to the nature of the scan the model was not used for surgical assessment, rather it was used to provide reference to ascertain the load bearing capabilities on different vertebrae. Surgeons found the tactile model to be helpful in planning future medical treatment for the patient.

21 CLINICAL USE 20: PROSTHETICS 3D PRINT MODEL TYPE: UPPER EXTREMITY PROSTHETICS KENYA, UGANDA, RWANDA, TANZANIA, SYRIA, LEBANON, MYANMAR, CAMBODIA 3D SCAN AND CAD MODEL FDM 3D PRINTER USING FLEXIBLE 3D FILAMENT 80% of the world s estimated 30 million amputees live in developing nations, who have little or no access to affordable and suitable prosthetics. 3DLP have developed the LifeArm, a functional and low cost 3D printed transradial prosthetic designed specifically for use in challenging environmental conditions. The use of 3D printing here provided an extremely low cost prosthetic for patients in the developing world. The LifeArm is designed to meet the requirements of the developing world and is, low-cost, lifelike, durable, and easy to maintain.

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