Product Overview Life Sciences & Industrial Division

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1 Product Overview Life Sciences & Industrial Division

2 IN CONTROL To meet the demand for instrumentation critical to life science research, we offer a unique line of piezoelectric-based positioning systems and high-performance mounting solutions for use with microscopes and manipulator assemblies. For more than twenty five years, Burleigh precision piezoelectric technology has enabled ground breaking biological research in cellular manipulation, electrophysiology and in vitro fertilization. SPEED. CONTROL. PRECISION. STABILITY. Burleigh delivers truly innovative and leading edge equipment with the use of such technologies as piezoelectrics (PZT). Only Burleigh s PZT technology offers: precise, fast, stable positioning; linear and low-noise electronics; fingertip commands that are instantly and precisely converted to smooth and precise pipette motion without drift.

3 SPEED Micromanipulators PCS-6000 The PCS-6000 micromanipulator offers extremely precise, fast, stiff and stable micropositioning for electrophysiology research. By being able to choose from a variety of configurations with the combination of motorized long travel and PZT smoothness, you have total control. PCS-5000 The PCS-5000 micromanipulator is the solution for total control in patch-clamp micromanipulation. With fingertip commands you have the ability to entirely control your pipette position with three linear axes of travel with 25mm of coarse movement and a choice of 150µm or 300µm of fine movement. 25mm of motorized travel for rapid coarse positioning PZT technology with nanometer precision for fine positioning 3-axis systems available with a variety of PZT configurations Negligible drift for ultra-high stability PCS-6000 controller can support an additional manipulator - the PCS-4100 Adjustable home positions on rotary pivot stages Solid ceramic PZT actuators expand under applied voltage Entire assembly rotates completely forward with adjustable set stops Linear low-noise electronics and cables are fully shielded and carefully grounded Negligible drift for ultra-high stability 25 mm of manual travel in all three axes Adjustable home positions on the two rotary stages Low-noise electronics and cables are fully shielded and carefully grounded Available in two configurations optimized for either brain slice or cultured cells (Burleigh manipulators) are extremely stable and precise, yet robust and exceptionally well made HI/LOW Axis Control Unit (PZT) Joy Stick (coarse movement)

4 Micromanipulators PCS-4100 The PCS-4100 micromanipulator was designed by and for electrophysiologists, primarily for patching cultured cells. The low-cost PCS-4100 is the only micromanipulator in the world to include memory positions on the Z axis as well as both rotary stages. Pipette exchange has never been faster or easier. LBM-07 The LBM-07 is a high precision, stable manual manipulator. With the ability to move in XYZ and approach, the LBM-07 also has horizontal and vertical rotary adjustment. Ideal for applications such as extracellular recording, positioning stimulating electrodes, puffer pipettes and probing large cells such as oocytes. 7 axes of movement (4 linear, 3 rotational) Full Range of mounting options Highly stable manipulator Minimal drift (< 1µm per hour) Very competitively priced PCS-500-SSH (Steep / Shallow Headstage Adapter) The PCS-500-SSH Steep/Shallow Headstage Adapter adds unprecedented flexibility for positioning the headstage. It allows the orientation of a headstage and pipette holder at very steep or shallow angles. And it further simplifies pipette exchange even when the pipette is in the tightest places. Its symmetrical design offers these capabilities from both the right and left side of the microscope. Holds the headstage Extends the headstage closer to the brain slice chamber and away from the manipulator Low cost micromanipulator User defined memory positions and user adjustable stops on rotary stages Ultra-high stability with negligible drift Quick to learn; easy to use PCS-4100 electronics controllers supports two manipulators Steep angle Shallow angle Quick and easy pipette exchange

5 Micromanipulators/Microinjection LSS-3000 LSS-8000 INCHWORM PiezoDrill The Piezoelectric Ultra-Fast Solution Switching Systems can change the chemical environment of a whole cell or excised patch with submillisecond time resolution. These systems are complete, practical and easy-to-implement approaches for rapidly moving a theta tube and its exiting solution stream. Positioning of microelectrodes for electrophysiology recordings require micrometer-scale control of high-velocity, high-acceleration steps. These steps must be achieved with minimum vibration to prevent damage to cells, their processes or connections. The INCHWORM motor systems helps cell physiologists obtain clean penetrations and stable cell recordings. The PiezoDrill inertial impact drill allows a genetically engineered nucleus to be deposited directly into the cytoplasm with negligible damage to the recipient oocyte. The PiezoDrill can also be used to greatly improve yields in intracytoplasmic sperm injection (ICSI) and nuclear transfer(nt) for mice and other species of interest. Up to 300 µm PZT travel Solid-state PZT actuators integrated with monolithic flexure stages Integrated manual stages & adjustments Switching times as fast as 150 micro seconds for excised patches 25mm of travel Programmable step-sizes in 0.5µm increments Solid-state construction High speed and acceleration Ultra Low Noise drive electronics Easy penetration of the zona with a large pipette with mechanical pulses Oolemma can be penetrated without suction Attaches to any commercial manipulator system Two-position footswitch Independent controls for pulse duration, frequency and amplitude

6 Microscope Mounts Gibraltar The Gibraltar Platform and X-Y Stage provide a complete solution for fixedstage upright microscopes. The microscope can be moved smoothly and precisely between fields of view without disturbing an established patch while the motorized X-Y stage ensures that you never lose a position of interest. PCS-500 Mounts PCS-500 Series Microscope Mounts are available to mount onto the most popular inverted microscopes. They are engineered to provide maximum stability as well as flexibility to meet the most demanding application needs. Motorized, hands-free movement 2 memory positions Flat mounting surfaces with standard tapped holes Stackable stages for multi-axis systems Wide range of accessories including choice of base, top and manual vs motorized movement Complete compatibility with major microscope manufacturers Sturdy, open platform design I would not hesitate to recommend your products to anyone over any of the competitive products

7 Sales & Customer Inquires Tel: Toll Free: (USA & Canada) Fax:

8 EXFO Life Sciences & Industrial Division 2260 Argentia Road, Mississauga, Ontario, L5N 6H7 Canada Tel: Fax: Toll Free: Website: Corporate Headquarters EXFO Electro-Optical Engineering Inc. 400 Godin Avenue, Vanier, Quebec, G1M 2K2 Tel: Fax:

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