UNIFI UNIFI Installation and Configuration Guide / Revision A Copyright Waters Corporation 2013 All rights reserved

Transcription

1 UNIFI UNIFI Installation and Configuration Guide / Revision A Copyright Waters Corporation 2013 All rights reserved

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3 General Copyright notice 2013 WATERS CORPORATION. PRINTED IN THE UNITED STATES OF AMERICA AND IN IRELAND. ALL RIGHTS RESERVED. THIS DOCUMENT OR PARTS THEREOF MAY NOT BE REPRODUCED IN ANY FORM WITHOUT THE WRITTEN PERMISSION OF THE PUBLISHER. The information in this document is subject to change without notice and should not be construed as a commitment by Waters Corporation. Waters Corporation assumes no responsibility for any errors that may appear in this document. This document is believed to be complete and accurate at the time of publication. In no event shall Waters Corporation be liable for incidental or consequential damages in connection with, or arising from, its use. For the most recent revision of this document, consult the Waters Web site (waters.com). Trademarks ACQUITY, ACQUITY UPLC, UPLC, Xevo, THE SCIENCE OF WHAT S POSSIBLE., and Waters are registered trademarks of Waters Corporation. UNIFI, Empower, and MassLynx are trademarks of Waters Corporation. Microsoft, DirectX, Internet Explorer, Windows, and Windows 7 are registered trademarks of Microsoft Corporation in the United States and/or other countries. NVIDIA is a registered trademark of NVIDIA Corporation in the US and other countries. Oracle is a registered trademark of Oracle Corporation and/or its affiliates. Intel is a registered trademark of Intel Corporation in the U.S. and/or other countries. Core and Xeon are trademarks of Intel Corporation in the US and other countries. Tesla is a trademark of Corporation in the U.S. and/or other countries. Other trademarks or registered trademarks are the sole property of their respective owners. Customer comments Waters Technical Communications organization invites you to report any errors that you encounter in this document or to suggest ideas for otherwise improving it. Help us better understand what you expect from our documentation so that we can continuously improve its accuracy and usability. We seriously consider every customer comment we receive. You can reach us at tech_ comm@waters.com. 18 October, 2013, Rev. A iii

4 Contacting Waters Contact Waters with enhancement requests or technical questions regarding the use, transportation, removal, or disposal of any Waters product. You can reach us via the Internet, telephone, or conventional mail. Waters contact information: Internet Telephone and fax Conventional mail The Waters Web site includes contact information for Waters locations worldwide. Visit From the USA or Canada, phone , or fax For other locations worldwide, phone and fax numbers appear in the Waters Web site. Waters Corporation 34 Maple Street Milford, MA USA iv 18 October, 2013, Rev. A

5 Preface Audience and purpose This guide is for those installing or upgrading UNIFI software. It provides the procedures required to install or upgrade and configure UNIFI software on a UNIFI workstation or a workgroup configuration. Updated information Refer to the Waters web site (Service & Support > Support > Support Library) for any updates to this guide. 18 October, 2013, Rev. A v

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7 Table of Contents General Copyright notice Trademarks Customer comments Contacting Waters Preface Audience and purpose Updated information iii iii iii iii iv v v v 1 Introduction to UNIFI 11 Waters UNIFI software 11 Identify workstation hardware and software requirements 13 Identify workgroup hardware and software requirements 16 2 Configuring the Hardware 23 Preparing for UNIFI software 23 Selecting the site 23 Environmental requirements 23 Space considerations 24 Power supply 25 Installing the hardware 25 Install UNIFI workstation hardware 25 Install UNIFI workgroup hardware 26 Connect Ethernet instruments 26 3 Installing a UNIFI Workstation 29 Before you begin installing a workstation 29 Install UNIFI software on a workstation 29 Before you begin 29 Configure the Windows firewall settings October, 2013, Rev. A vii

8 Install UNIFI software on a workstation 32 Log on to the UNIFI portal 33 Activate UNIFI licenses 33 Register and activate licenses 34 View active licenses 35 Create a new administrator account 35 Install a Microsoft loopback network adapter 37 Remove UNIFI software from a workstation 38 4 Installing a UNIFI Workgroup 41 Before you begin installing a workgroup server 41 Choose a database backup option 41 Configure disk drives 43 Create Windows application server role 44 Install UNIFI software on a workgroup server 45 Before you begin 46 Verify Windows hosts file information 46 Enable the correct option for Windows updates 46 Configure network discovery and file and printer settings 47 Configure the network LAN 47 Confirm regional settings 48 Identify location for database backup copies 48 Install UNIFI software on a workgroup server 48 Log on to the UNIFI portal 50 Activate UNIFI licenses 51 Register and activate licenses 52 View active licenses 53 Create a new administrator account 53 Install UNIFI software on a client 55 Before you begin 55 Turn on MSMQ Server 55 Configure the power options 56 Turn on network discovery and file and printer sharing settings 57 Enable the correct option for Windows updates 57 Verify connectivity between the client and workgroup server 57 Install UNIFI software on a client 57 Install UNIFI software on a laboratory network device 58 viii 18 October, 2013, Rev. A

9 Before you begin 59 Install UNIFI software on a custom laboratory network device 59 Enable the correct option for Windows updates 59 Turn on network discovery and file and printer sharing settings 60 Turn on the Microsoft Message Queue Server 60 Configure the power options 60 Configure the Instrument LAN 61 Configure the Windows firewall settings 62 Install UNIFI software on a laboratory network device 62 Automate database backups to a network location 63 Create an OS user account with the correct permissions 64 Create a network share to store database backups 64 Add credentials to automatically access the network share 65 Create the OracleCRSToken Service and then manually set the password 66 Stop the database and Oracle listener 66 Stop services 67 Grant permissions to the named user 67 Start services 67 Modify the database backup tasks to run as the local or domain user account 67 Start the database and then restart the server 68 Verify backups are copied to network location 68 Remove UNIFI software from a workgroup configuration 68 5 Managing the Database 71 Back up the workstation database 71 Before you back up the workstation database 71 Windows user groups 71 Back up database to default location 72 Back up database to a specified location 72 Managing backup-related files 73 Restore the workstation database 73 Before you restore the workstation database 74 Restore database from a specified location 75 6 Verifying the installation 77 Verify installed files on a workstation 77 Verify installed files for a workgroup 78 7 Troubleshooting 81 Record a problem October, 2013, Rev. A ix

10 UNIFI Installation troubleshooting 81 A GMP Default Installations 87 Default settings overview 87 Data folders 89 Global policies 90 Audit Trail Reasons global policy 90 Date and time global policy 91 Audit Trail global policy 92 Timeout global policy 92 User Account global policy 93 Qualification global policy 93 Folder policies 94 Roles 96 Predefined reasons 100 Predefined meanings and comments 108 Custom fields 109 User account 109 Event properties 110 x 18 October, 2013, Rev. A

11 1 Introduction to UNIFI Contents: Waters UNIFI software 11 Identify workstation hardware and software requirements 13 Identify workgroup hardware and software requirements 16 Waters UNIFI software The Waters UNIFI workstation configuration consists of the following components: Workstation components UNIFI software Database Workstation Waters instrument systems Purpose Control instruments and devices to acquire, analyze, process, and report data, and to perform other information management functions. Stores the metadata or descriptive information about the samples run (processed results, sample identifiers, methods, and reports), in a relational database management system (RDBMS). Raw data are also stored in the database. Runs on the Microsoft Windows 7 Professional SP 1, 64-bit operating system (OS). Groups of chromatographic instruments and mass spectrometers that you create to form an instrument system. These systems, which connect to a workstation, perform chromatographic (LC) and mass spectrometric (MS) analyses. For example, a UNIFI instrument system based on Waters UPLC technology can include solvent manager, sample manager, column manager, one or more detectors, chromatographic columns, and an e-sat/in module. For MS analyses, its configuration can include a Xevo mass spectrometer. The number of instrument systems supported by a UNIFI workstation depends on the type of detector included in the instrument system. Number of instrument systems supported by a UNIFI workstation: One instrument system that contains a quadruple mass spectrometer, or One instrument system that contains a TOF (time of flight) mass spectrometer, or Two instrument systems that contain optical detectors, such as a PDA or TUV The Waters UNIFI workgroup configuration consists of the following components: 18 October, 2013, Rev. A 11

12 1 Introduction to UNIFI Workgroup components UNIFI software Workgroup server Laboratory network devices Purpose Control instruments and devices to acquire, analyze, process, and report data, and to perform other information management functions. Stores the metadata or descriptive information about the samples run (processed results, sample identifiers, methods, and reports), in a relational database management system (RDBMS). Raw data are also stored in the database. The Oracle Enterprise Manager (OEM) allows for monitoring and some management functions of the UNIFI database. UNIFI software also supports Oracle Automatic Storage Management (ASM) for disk management (data files, redo logs, control files) on physical internal or external disks like a storage area network (SAN) disk. Collect all data acquired by Waters instrument systems. Recommendation: Procure a pre-configured LND from Waters. Doing so, is more efficient than performing the labor-intensive work of configuring a computer to serve as an LND. The number of online instrument systems per LND depends on the type of detector included in the instrument system. Maximum number of online instrument systems per LND: One instrument system that contains a quadruple mass spectrometer, or One instrument system that contains a TOF (time of flight) mass spectrometer, or Two instrument systems that contain optical detectors, such as a PDA or TUV October, 2013, Rev. A

13 Identify workstation hardware and software requirements Workgroup components Purpose Waters instrument systems Client computers Local area network (LAN) Groups of chromatographic instruments and mass spectrometers that you create to form an instrument system. These systems, which connect to laboratory network devices, perform chromatographic (LC) and mass spectrometric (MS) analyses. For example, a UNIFI instrument system based on Waters UPLC technology can include solvent manager, sample manager, column manager, one or more detectors, chromatographic columns, and an e-sat/in module. For MS analyses, its configuration can include a Xevo mass spectrometer. The number of instrument systems supported by a UNIFI workgroup depends on the type of detector included in the instrument system. Your instrument systems can include a combination of mass spectrometers and optical detectors such as PDAs or TUVs, but cannot include a combination of quadruple and TOF (time of flight) mass spectrometers. Number of instrument systems supported by a UNIFI workgroup: Four instrument systems that contains a quadruple mass spectrometer, or Two instrument systems that contains a TOF (time of flight) mass spectrometer, or Six instrument systems that contain optical detectors, such as a PDA or TUV Refer to the example below this table for the maximum number of instrument systems supported by a UNIFI workgroup. Access UNIFI software installed on the workgroup server. Interconnects all devices that comprise a workgroup. You cannot use a WAN (wide area network) configuration. Identify workstation hardware and software requirements The following table describes the recommended hardware, software, and operating system requirements for a UNIFI workstation that includes an instrument system comprised of a quadruple mass spectrometer or an optical detector, such as a PDA or TUV. 18 October, 2013, Rev. A 13

14 1 Introduction to UNIFI Recommended workstation configuration: Component Application software OS Processor Random-access memory (RAM) Hard disk drive Optical drive Virtual memory Monitor Network adapter card Video card Requirement UNIFI v1.7 software Windows 7 Professional SP1 (64-bit) with MSMQ Server enabled. Intel Xeon E Processor (2.0 GHz) 16 GB Two x 2 TB SATA 7.2K hard drives Tip: The installer requires a minimum of 40 GB. DVD Let Windows manage the virtual memory. A minimum resolution of 1024 x 768, but the recommended resolution is 1900 x Two 10/100/1000 GB network adapter ports Discrete video card, with a minimum of 1 GB of memory (DirectX 11 or higher compatible.) The following table describes the minimum hardware, software, and operating system requirements for a UNIFI workstation that includes an instrument system comprised of a quadruple mass spectrometer or an optical detector, such as a PDA or TUV. Minimum workstation configuration: Component Application software OS Processor Random-access memory (RAM) Hard disk drive Optical drive Virtual memory Monitor Network adapter card Video card Requirement UNIFI v1.7 software Windows 7 Professional SP1 (64-bit), with MSMQ Server enabled. Intel Xeon E5507 (2.26 GHz) 12 GB Two 1TB 7.2K SATA drive Tip: The installer requires a minimum of 40 GB. DVD Let Windows manage the virtual memory. A minimum resolution of 1024 x 768, but the recommended resolution is 1900 x Two 10/100/1000 GB network adapter ports Discrete video card, with a minimum of 512 MB of memory (DirectX 11 or higher compatible.) October, 2013, Rev. A

15 Identify workstation hardware and software requirements The following table describes the recommended and minimum hardware, software, and operating system requirements for a UNIFI workstation that includes a TOF (time of flight) mass spectrometer. Minimum and recommended workstation configuration: Component Application software OS Processor Random-access memory (RAM) Hard disk drive Optical drive Virtual memory Monitor Network adapter card Video card GPU card Requirement UNIFI v1.7 software Windows 7 Professional SP1 (64-bit) with MSMQ Server enabled. Dual Intel Xeon E processors (2.0 GHz) 64 GB One x 256GB 2.5-inch SATA Solid State disk Two x 2TB SATA 3.5-inch 7.2K hard drives Tip: The installer requires a minimum of 40 GB. DVD Let Windows manage the virtual memory. A minimum resolution of 1024 x 768, but the recommended resolution is 1900 x Two 10/100/1000 GB network adapter ports Discrete video card, with a minimum of 1 GB of memory (TESLA GPU card.) GPU-based processing is supported. Supported cards: NVIDIA Tesla GPU C2050, C2070, and C2075. Recommended card: NVIDIA Tesla GPU C2075. The following table describes the recommended hardware, software, and operating system configuration required for a process-only workstation. Recommended process-only workstation configuration: Component Application software OS Processor Random-access memory (RAM) Requirement UNIFI v1.7 software Windows 7 Professional SP1 (64-bit) with MSMQ Server enabled. Intel Xeon E Processor (2.0 GHz) 16 GB 18 October, 2013, Rev. A 15

16 1 Introduction to UNIFI Component Hard disk drive Optical drive Virtual memory Monitor Network adapter card Video card Requirement Two x 2 TB SATA 7.2K hard drives Tip: The installer requires a minimum of 40 GB. DVD Let Windows manage the virtual memory. A minimum resolution of 1024 x 768, but the recommended resolution is 1900 x Two 10/100/1000 GB network adapter ports Discrete video card, with a minimum of 1 GB of memory (DirectX 11 or higher compatible.) The following table describes the minimum hardware, software, and operating system configuration required for a process-only workstation. Minimum process-only workstation configuration: Component Application software OS Processor Random-access memory (RAM) Hard disk drive Optical drive Virtual memory Monitor Network adapter card Video card Requirement UNIFI v1.7 software Windows 7 Professional SP1 (64-bit) with MSMQ Server enabled. Intel CoreTM i5 16 GB A single 1 TB 7.2K SATA drive with a minimum of 250 GB free space on the C drive. Tip: The installer requires a minimum of 40 GB. DVD Let Windows manage the virtual memory. A minimum resolution of 1024 x 768, but the recommended resolution is 1900 x Single GB 10/100/1000 network adapter card Discrete video card with a minimum of 512 MB of memory Identify workgroup hardware and software requirements A 100/1000, Ethernet high-speed network connection must connect the client, laboratory network device, and workgroup server in a local area network (LAN) configuration. Restriction: You cannot use a WAN (wide area network) configuration October, 2013, Rev. A

17 Identify workgroup hardware and software requirements The following table describes the recommended and minimum hardware, software, and operating system requirements for a UNIFI client in a workgroup configuration that includes a quadruple mass spectrometer or an optical detector, such as a PDA or TUV. Recommended and minimum configuration for a UNIFI client: Component Application software OS Processor Random-access memory (RAM) Hard disk drive Optical drive Virtual Memory Monitor Network adapter Card Video card Requirement UNIFI v1.7 software Windows 7 Professional SP1 (64-bit) Recommended: Intel CoreTM i5 Processor (3.30 GHz) Minimum: Intel CoreTM Duo Processor (2.66 GHz) Recommended: 8 GB Minimum: 4GB A minimum of 250 GB free space. Tip: The installer requires a minimum of 11 GB. DVD Let Windows manage the virtual memory. A minimum resolution of , but the recommended resolution is One GB network adapter port Embedded video card with a minimum of 512 MB of memory. The video card must be DirectX 11 or higher compatible. The following table describes the recommended and minimum hardware, software, and operating system requirements for a UNIFI client in a workgroup configuration that includes a TOF (time of flight) mass spectrometer. Recommended and minimum configuration for a UNIFI client: Component Application software OS Processor Random-access memory (RAM) Hard disk drive Optical drive Requirement UNIFI v1.7 software Windows 7 Professional SP1 (64-bit) Intel CoreTM i5 Processor (3.30 GHz) 16 GB A minimum of 250 GB free space on the C drive. Tip: The installer requires a minimum of 11 GB. DVD 18 October, 2013, Rev. A 17

18 1 Introduction to UNIFI Component Virtual Memory Monitor Network adapter Card Video card Requirement Let Windows manage the virtual memory. A minimum resolution of , but the recommended resolution is One GB network adapter card Embedded video card with a minimum of 512 MB of memory. The video card must be DirectX 11 or higher compatible. Recommended and minimum configuration for a UNIFI laboratory network device: Component Requirement Application software UNIFI v1.7 software OS Processor Random-access memory (RAM) Virtual memory Hard disk drive Optical drive Network adapter card Windows 7 Embedded Standard SP1 (for the LND provided by Waters Corporation only). Windows 7 Professional SP1 (64-bit) with MSMQ Server enabled Intel CoreTM 2 Duo Processor E8400 (3.0 GHz, 1333 MHz FSB) 8 GB Double the amount of physical RAM A minimum of 250 GB of free space ensures enough space in the event data buffering occurs on the LND. Tip: The installer requires a minimum of 11 GB. DVD Two 10/100/1000 GB network ports The following table describes the recommended and minimum hardware, software, and operating system requirements for a UNIFI workgroup server in a workgroup configuration that includes a quadruple mass spectrometer, or an optical detector, such as a PDA or TUV. Recommended and minimum configuration for a UNIFI workgroup server: Component OS Processor Application software Randomaccess memory (RAM) Requirement UNIFI v1.7 software Windows Server 2008 R2 Standard SP1 (64-bit) Two Intel Xeon E5640 Processor at 2.66 GHz 24 GB October, 2013, Rev. A

19 Identify workgroup hardware and software requirements Component Requirement Virtual memory Disk drives Server storage Oracle Data Group and FRA hard disk drives Optical drive Twice the amount of RAM. Two 600 GB 10K SAS drives RAID 1 (mirrored) for the operating system. Tip: The installer requires a minimum of 40 GB. Data drives: 900 GB 10K SAS drives RAID 1 1x hot spare FRA (Fast Recovery Area) drives: 1 TB 7.2K NL SAS drives RAID 5 (striped with parity) 1x hot spare Waters recommends: During software installation, select the Oracle ASM External Redundancy option. For instrument systems that include quadruple mass spectrometers or optical detectors these drives: 6 data group drives, which provide 2.7 TB of usable space. 6 FRA drives, which provide 5 TB of usable space. Tips: The FRA storage size is based on the requirement that storage must be large enough to accommodate two full database backups. The old backup is not deleted until the new backup is complete. RMAN backups are compressed by approximately 33%. As your data group grows, the FRA storage location must grow accordingly. Calculation: Data group size x 2 database backups x 0.66 compression rate. DVD - Read/Write Monitor A minimum resolution of Network adapter card Recommended: Dual port gigabit, network server adapter, NIC card The following table describes the recommended and minimum hardware, software, and operating system requirements for a UNIFI workgroup server in a workgroup configuration that includes a TOF (time of flight) mass spectrometer. 18 October, 2013, Rev. A 19

20 1 Introduction to UNIFI Recommended and minimum configuration for a UNIFI workgroup server: Component Requirement OS Processor Application software Randomaccess memory (RAM) Virtual memory Disk drives Server storage Oracle Data Group and FRA hard disk drives Optical drive UNIFI v1.7 software Windows Server 2008 R2 Standard SP1 (64-bit) Two Intel Xeon E5640 Processor at 2.66 GHz 24 GB Twice the amount of RAM. Two 600 GB 10K SAS drives RAID 1 (mirrored) for the operating system. Tip: The installer requires a minimum of 40 GB. Data drives: 900 GB 10K SAS drives RAID 1 1x hot spare FRA (Fast Recovery Area) drives: 1 TB 7.2K NL SAS drives RAID 5 (striped with parity) 1x hot spare Waters recommends: During software installation, select the Oracle ASM External Redundancy option. For instrument systems that include quadruple mass spectrometers or optical detectors these drives: 16 data group drives, which provide 7.2 TB of usable space. 12 FRA drives, which provide 11 TB of usable space. Tips: The FRA storage size is based on the requirement that storage must be large enough to accommodate two full database backups. The old backup is not deleted until the new backup is complete. RMAN backups are compressed by approximately 33%. As your data group grows, the FRA storage location must grow accordingly. Calculation: Data group size x 2 database backups x 0.66 compression rate. DVD - Read/Write October, 2013, Rev. A

21 Identify workgroup hardware and software requirements Component Requirement Monitor A minimum resolution of Network adapter card Recommended: Dual port gigabit, network server adapter, NIC card 18 October, 2013, Rev. A 21

22 1 Introduction to UNIFI October, 2013, Rev. A

23 2 Configuring the Hardware Contents: Preparing for UNIFI software 23 Selecting the site 23 Installing the hardware 25 Preparing for UNIFI software Except for a UNIFI workstation, all configurations require a pre-existing local area network (LAN), so that the Workgroups system can function. Waters personnel do not install network cables. To install and activate Waters licenses and options, you must use a computer connected to the Internet. Note, however, that this computer need not be the one running UNIFI software. Before installing any hardware or software, it is wise to perform a full backup of your hard drives (see instructions provided by the manufacturer of your computer). After the installation, back up UNIFI data regularly. Selecting the site Locate the UNIFI system in a clean area that is free from shock, vibration, and extremes of temperature and humidity. Environmental requirements Install theunifi system in a draft-free position protected, away from excessive amounts of dust. Protect equipment from direct sunlight and heating and air conditioning vents. Temperature and humidity The UNIFI system can operate within the following temperature and humidity ranges: Maintain an ambient temperature of between 15 and 28 C Ensure the ambient humidity does not exceed 80% relative humidity, non-condensing Acceptable temperature and humidity ranges vary according to the model of the computer and printer. Vibration Do not install the UNIFI system near heavy machines such as compressors and generators, which can create excessive floor vibration. 18 October, 2013, Rev. A 23

24 2 Configuring the Hardware Magnetic fields If the UNIFI system includes a mass spectrometer, position the system away from strong magnetic fields such as those generated by NMR systems or magnetic-sector mass spectrometers. Radio emissions Install the UNIFI system in an environment where radio frequency (RF) emission from surrounding sources is minimal. Possible sources of RF emission include RF-linked alarm systems, mobile telephones, and hand-held transmitters. Exhaust outlets If a UNIFI system includes a chromatographic system or mass spectrometer, to avoid exposure to solvent vapors, refer to the system's site preparation guide for exhaust requirements. Space considerations Allow sufficient bench space for the UNIFI personal workstation, Workgroup, or client computers (keyboard, monitor, system unit, and printer), as recommended in the documentation supplied with the computer. For workstation installations, place computers on a lab bench or a desktop near the system instruments to enable control and tuning of the chromatography or MS system. The total bench space you require depends on the number of devices you plan to configure (pumps, detectors, autosamplers, and so on). For Workgroup installations, place the laboratory network device and the client computer on a lab bench or a desktop near the system modules. Locate the workgroup server in a separate server room managed by IT personnel. Other client computers can be located anywhere on the network or domain. Ventilation Ensure the ventilation slots on all system modules are not blocked. Allow at least 15 cm of space on all sides of each module to ensure adequate air flow. Cable lengths Arrange the components of a chromatographic system to minimize cable lengths. Use optimal lengths to ensure proper signal transmission. All Waters instruments are shipped domestically with a 2.3-m power cord connected to the rear of the chassis. International power cords are 2.5 m. For the data system (computer, monitor, keyboard, mouse), if required, you can use extension cables from a PC vendor. Instrument arrangement Place the workstation or client computer (computer, monitor, keyboard, mouse) or the laboratory network device (computer only) on a laboratory bench close to the system modules. If October, 2013, Rev. A

25 Installing the hardware the UNIFI system includes a mass spectrometer, locate the data system within 5 m of the mass spectrometer, to allow connection of the communication cables. For information on the best arrangement of your UNIFI system and connected instruments, consult your Waters technical service representative. Power supply All UNIFI system components require a dedicated, earthed (grounded) power source. Ensure that the power supply cables of the system modules easily reach the electrical outlets connected to a common ground. Consider using a line conditioner or an uninterruptible power supply (UPS), for optimum long-term input-voltage stability. If a UNIFIsystem includes a chromatographic system or a mass spectrometer, refer to its site preparation guide for the following power requirements: Power supply Electrical transformers Uninterruptible power supply Installing the hardware Install UNIFI workstation hardware The UNIFI workstation supports an optional, second, interface card for Ethernet instruments. If you install UNIFI software on a computer that is not included in a network, you must install a Microsoft loopback network adapter (see "Install a Microsoft loopback network adapter"). To set up a UNIFI workstation: 1. Unpack and place the workstation in its final location. 2. Connect the keyboard, mouse, and monitor to the workstation. 3. Ensure the voltage-selection switch on the PC tower is set to the correct voltage for the laboratory supply. 4. To install other computer peripherals, such as a printer, see the installation documentation supplied with the device. 5. Switch on the PC, monitor, and peripheral devices. 6. Login to the Microsoft Windows 7 desktop using the administrator account with the password "waters". 7. If required, change the PC name and domain, and then connect to your facility's network. 8. If applicable, connect the Ethernet devices (see "Connect Ethernet instruments"). 18 October, 2013, Rev. A 25

26 2 Configuring the Hardware Install UNIFI workgroup hardware The UNIFI workgroup system comprises a server, one or more clients, and one or more laboratory network devices. Each computer in the workgroup system requires at least one network interface card. Ethernet instruments in a UNIFI workgroup connect to a laboratory network device. To set up a UNIFI workgroup server: 1. Unpack and place the server in the desired location. 2. Connect the keyboard, mouse, and monitor to the server. 3. To install other computer peripherals, such as a printer, refer to the installation documentation supplied with the device. 4. Ensure that the network interface card is installed in the server. To set up a UNIFI workgroup client: 1. Unpack and place the client in the desired location. 2. Connect the keyboard, mouse, and monitor to the client. 3. Ensure that the network interface card is installed in the client. 4. Repeat step 1 through step 3 for each client in the workgroup system. 5. Connect the client to the network. To set up a UNIFI laboratory network device: 1. Unpack and place the laboratory network device in its final location. 2. Ensure that the network interface card is installed in the laboratory network and set up correctly. 3. Ensure that a second network interface card is present. 4. Connect the laboratory network device to the network. 5. Connect the Ethernet devices (see "Connect Ethernet instruments"). Connect Ethernet instruments Ethernet instruments connect directly to a network interface card (NIC) installed in a workstation or laboratory network device. If you are connecting multiple Ethernet instruments, use a Waters-supplied switch to connect the Ethernet cable from the workstation or laboratory network device to the switch. Then plug each instrument into the switch. The NIC used for instrument connections is separate and apart from the NIC used to communicate with your facility's network. Multiple Ethernet connections require crossover cables to control a mass spectrometer through a network switch. In addition, resetting the link speed and duplex properties of an NIC to Auto Detect can be necessary. In both cases, if you are using more than one NIC, you can modify the settings for a second NIC using the DHCP wizard after you install UNIFI software October, 2013, Rev. A

27 Installing the hardware See the Ethernet Getting Started Guide for more information on connecting and configuring Ethernet devices. 18 October, 2013, Rev. A 27

28 2 Configuring the Hardware October, 2013, Rev. A

29 3 Installing a UNIFI Workstation Contents: Before you begin installing a workstation 29 Install UNIFI software on a workstation 29 Log on to the UNIFI portal 33 Activate UNIFI licenses 33 Create a new administrator account 35 Install a Microsoft loopback network adapter 37 Remove UNIFI software from a workstation 38 Before you begin installing a workstation Before you begin the installation, complete these tasks: Ensure the workstation meets the minimum requirements for hardware and software. Verify that the disk drive has enough space to install UNIFI software. If installing UNIFI software on a computer not included in a network, install the Microsoft loopback adapter. Close all other applications and restart the workstation. See also: Identify workstation hardware and software requirements Install a Microsoft loopback network adapter Install UNIFI software on a workstation The Waters UNIFI installation wizard guides you through the installation process. Allow approximately 30 minutes to complete the installation. Caution: After you install UNIFI software on a workstation, Waters recommends that you do not change the IP address or computer name of the workstation. Changing either of these may render UNIFI software unusable. Before you begin Before you install UNIFI software on a workstation, perform these tasks: Configure the instrument LAN Configure the Windows firewall settings Turn on MSMQ Server Enable the correct option for Windows updates 18 October, 2013, Rev. A 29

30 3 Installing a UNIFI Workstation If you are using real-time virus scanning, exclude all UNIFI related folders and their sub-directories. Some real-time virus scanners mistake normal UNIFI software functionality for virus activity, causing data buffering problems. Configure the Instrument LAN You must configure the power management settings and assign the IP address for the Instrument LAN to communicate with the instruments. Log on to the workstation as the local administrator. Configure the power management settings and rename the connection to Instrument LAN Configure IP address To configure the power management settings: 1. Click Start > Control Panel > Network and Internet > Network and Sharing Center > View network status and tasks > Change adapter settings. 2. Right-click on Local Area Connection, select Rename, and type Instrument LAN. 3. Right-click Instrument LAN, and then click Properties. If you are instructed to enter an administrator password or confirmation, do so. 4. On the Networking tab, click Configure. 5. On the Power Management tab, clear the "Allow the computer to turn off this device to save power" checkbox, and then click OK. To configure the IP address: 1. Click Start > Control Panel > Network and Internet > Network and Sharing Center > View network status and tasks > Change adapter settings. 2. Right-click Local Area Connection, Instrument LAN, and then click Properties. 3. On the Networking tab, clear the Internet Protocol Version 6 (TCP/IPv6) checkbox. 4. Select Internet Protocol Version 4 (TCP/IPv4), and then click Properties. 5. In the Internet Protocol Version 4 (TCP/IPv4) Properties dialog box, click "Use the following IP address". 6. Assign the following IP address and Subnet mask, and then click OK: IP address: Subnet mask: Result: The assigned setting is saved for the local area connection, instrument LAN. Configure the Windows firewall settings For a laboratory network device, you must configure Windows firewall settings to turn off the Windows firewall for the Instrument LAN (public network). Tip: For the instruments to communicate with the LND, you must configure the LND's Windows firewall settings October, 2013, Rev. A

31 Install UNIFI software on a workstation To configure the Windows firewall settings: 1. Click Start > Control Panel > Network and Internet > Network and Sharing Center > Windows Firewall. Alternative: Right-click Network from the desktop and then select Properties > Windows Firewall. 2. On the Windows Firewall page, click "Turn Windows Firewall on or off". 3. On the Customize Settings page, perform these tasks, and then click OK: Click "Turn on Windows Firewall" for the "Home or work (private) location settings". Click "Turn off Windows Firewall (not recommended)" for the "Public network location settings". Turn on Microsoft Message Queue Server You must turn on MSMQ Server to run the installation wizard. When you fail to do so, the wizard closes. To turn on MSMQ: 1. Click Start > Control Panel > Programs > Programs and Features. 2. Click the option "Turn Windows features on or off". 3. In the Windows Features dialog box, expand Microsoft Message Queue (MSMQ) Server, and then expand Microsoft Message Queue (MSMQ) Server Core. 4. Select MSMQ HTTP Support and MSMQ Triggers. Tip: Do not select MSMQ Active Directory Domain Services Integration and Multicasting Support. 5. Click OK, and then wait while the features are configured. Enable the correct option for Windows updates You must select the option "Check for updates, but let me choose whether to download them". To specify the correct option for Windows updates on a client: 1. From Windows Control Panel, click "System and Security". 2. From the System and Security page, click "Windows Update". 3. From the Windows Update page, click "Change settings" page. 4. In the Important updates section of the Change Settings page, select "Check for updates, but let me choose whether to install them" option, and then click OK. 18 October, 2013, Rev. A 31

32 3 Installing a UNIFI Workstation Install UNIFI software on a workstation When you install UNIFI software on a workstation, the language installed is based on the workstation's operating system language. If the workstation's operating system is English, the software is installed in English. You cannot install the Japanese version of UNIFI software, on an English workstation. Requirement: You must have unrestricted local Windows administrator or equivalent privileges to install UNIFI v1.7 software. To install the UNIFI software: 1. Insert the UNIFI DVD into your computer's DVD drive. Tip: If the installer does not automatically open, open Window's Explorer, browse to the DVD drive, and double-click Setup.exe. 2. From the installation menu, click "Install UNIFI on a workstation". 3. On the Waters Software License Agreement page, read the agreement, click "I accept the terms of the license agreement", and then click Next. 4. On the Select an Installation Drive page, select a drive other than the OS (operating system) drive to install the software on. 5. On the Import Database page, perform one of these operations: If you are migrating the database to this computer, click Yes, and then specify the location of the database file that you previously exported. If you are performing a new installation, and not migrating the database, click Next. 6. On the Configure UNIFI policy and audit trail settings page, perform one of these operations: To comply with GxP guidelines and regulations, click "Configure settings for a regulated environment (GxP)". To configure settings for a unregulated environment, click "Configure settings for a non-regulated environment". See also: Appendix A for system policy and audit trail settings for a regulated and unregulated environment. 7. On the Ready to Install page, click Install. 8. On the Confirmation page, click Finish Tip: If the installation failed, click the link to open the Waters Installation Summary. If the software was not successfully installed, submit a request for Waters technical support at this web address: If you close the installation wizard and you want to open the installation log, browse to C:\Windows\WatersInstallationSummary. See also: For instructions on how to qualify the software, see the Workstation Qualification Protocol which is available on the UNIFI Qualification media. For more information about qualification, refer to the "Qualification Overview" document on this media October, 2013, Rev. A

33 Log on to the UNIFI portal After you install UNIFI software on a workstation After you install UNIFI software on a workstation, you can install a UNIFY print driver; however, you must install UNIFI software first and then the UNIFY print driver. For instructions on how to install the UNIFY print driver, see the NuGenesis 8 Installation and Configuration Guide. Log on to the UNIFI portal After you install UNIFI, you must log on to the UNIFI portal to register the software and activate your licenses. Tip: When you restart the workstation, wait at least five minutes before logging on to UNIFI software to allow time for Waters Service Host to restart. You can have 3 open Portal sessions open on a workstation. To log on to UNIFI software: 1. On your desktop, double-click UNIFI Portal. 2. In the Login dialog box, type "administrator" in both the User name and password fields. 3. On the Welcome page, click Administration, and then click Licensing, where you register and activate product licenses. Activate UNIFI licenses Use the Waters Licensing Management System to activate or deactivate the purchased software's product licenses and options. Waters' licenses apply to a UNIFI system and user accounts. You can assign and revoke UNIFI named-user licenses to user accounts as needed. Workstation license and options: License type System base UNIFI nameduser Large molecule Required Yes No No Definition There are two types of system base licenses: workstation and process-only. Both licenses configure the database as a UNIFI workstation and include 5 named-user licenses, but the process onlybase license doesn't allow data acquisition. If you want to support more than five active users, you can activate additional named-user licenses. Named-user licenses are required for users to log on to the software. If your instrument system includes a time of flight (TOF) mass spectrometer, this license is required to perform mass spectrometrybased analysis. 18 October, 2013, Rev. A 33

34 3 Installing a UNIFI Workstation License type Small molecule Waters scientific library Required No No Definition If you want to process the data using the Dealkylation, MassFragment and IsoScore tools, this license is required. If you want to import a Waters scientific library, the appropriate library license is required. Tip: You can import and export your own scientific library. Qualification licenses: License type Qualificationsoftware Qualificationinstrument Required for qualification Yes Yes Definition If you want to qualify the workstation, you must purchase a license for the workstation. To qualify instruments on a workstation, you must activate these licenses: The UNIFI Instrument Qualification Module license is required for each LC instrument included in an instrument system. The UNIFI Instrument Qualification Standard Technology MS license is required for each Xevo TQ, Xevo TQD, Xevo TQ-S mass spectrometer. The UNIFI Instrument Qualification High Technology MS license is required for Xevo G2 TOF, Xevo G2 -S TOF, Xevo G2-S Q TOF mass spectrometers. The UNIFI Instrument Qualification Accessory license is required for each instrument accessory module. After you install UNIFI software, you must register, activate, and assign UNIFI named-user licenses to users by using the licensing wizard in UNIFI software and the Internet as follows: Create a software registration file using the licensing wizard. Submit the software registration file to the Waters License Activation Center Web site, and receive a license activation file. Activate your licenses and options using the licensing wizard and the license activation file. Register and activate licenses You must register and activate the UNIFI base license to access UNIFI software. You can activate licenses other than the base license at the same time or after activating the base license, but not before doing so October, 2013, Rev. A

35 Create a new administrator account Pre-requisite: To complete the licensing process, you must have purchased UNIFI licenses from Waters and obtained a serial number for each purchased license. To register licenses: 1. On the Licensing Home page, click Register Software. 2. On the Request Software page, perform these tasks, and then click Next: Type a new name for the software registration file, or allow the default name to remain unchanged. The names of all registration files must include the *.lic extension. Select the location of the license registration file. This file stores your license registration information. 3. When the Register Software page reappears, perform one of the actions in the following table, depending on whether your computer has Internet access: Internet access Yes No Action Click the hyperlink to connect to the Waters License Activation Center web site. Move the software registration file that you just created to a computer with Internet access and then access Follow the instructions to activate your licenses. After you receive the activation file, move the file to the computer on which UNIFI software is installed. 4. When you obtain a license activation file, return to the licensing home page, and click Activate Licenses. 5. On the Activate Licenses page, select the license activation file you downloaded from the Waters License Activation Center Web site, and then click Next. 6. On the Activate Licenses - License Activation Complete page, click Finish. Tip: If you are activating the base license, log out and then log back on to UNIFI software to access the software's complete functionality. View active licenses To view all activated licenses available for deactivation, click Deactivate Licenses from the Licensing home page. The Deactivate License page displays a list of all activated licenses and options, as well as, unused qualification licenses. To view Qualification licenses, access the Qualification center (Qualification and Maintenance > Manage > Administration > Licenses). Create a new administrator account Administration > Security > Users > Create > User Editor 18 October, 2013, Rev. A 35

36 3 Installing a UNIFI Workstation After you activate licenses, Waters recommends that you create a new administrator account, and disable the administrator account shipped with the software. In the event that your administrator account becomes locked, Waters provides a utility to unlock the default administrator account. See also: UNIFI System Administrator's Guide for information on the unlocking the default administrator account. To create a new administrator account and assign it a license: 1. Log on to UNIFI Portal and then click Administration. 2. From the Security area, click Users. 3. From the Global User List page, click Create. 4. In the Account Settings tab of the User Editor, enter the information for the administrator account. User settings: Option User Name First Name Last Name Assigned roles Default role Description Type a combination of your last name and first name. User account names must be unique. Because administrator is the default user name, you must type a user name other than "administrator", preferably a combination of your last and first name. Type your first name. Type your last name. Click System Administrator. Click Administrator. Tip: There is no need to enter a password for this account. The first time you log on to UNIFI software with this account, the password defaults to your username and you must change the password. 5. Click Save. 6. Click Administration, and then click Assign Licenses from the Licensing section. 7. On the Assign License page, assign to the new administrator account a license. Tip: When you assign a license, you do not need to confirm the action by clicking Save. After you create a new administrator account and assign it a license, you must revoke the license from the default administrator account, and then disable the user account October, 2013, Rev. A

37 Install a Microsoft loopback network adapter To revoke the administrator account license and then disable it: 1. Click Administration > Licensing > Assign Licenses. 2. On the Assign Licenses page, click "Administrator, UNIFI", and then right-click Revoke. Result: The number of available licenses increases by Click Administration > Security > Users. 4. From the Global User list, click administrator (UNIFI, administrator) user account, and then click Modify. 5. In the Account Settings tab of the User Editor, select Disabled from the Current Status field. 6. Click Save. See also: Activate UNIFI licenses Install a Microsoft loopback network adapter You must install a Microsoft loopback network adapter if you install UNIFI software on a computer that is not included in a network. By installing the network adapter and using the computer s IP address, you simulate a networked computer. To install a Microsoft loopback adapter, do as follows: Add the loopback adapter hardware to your computer. Set up a network connection for the adapter. To add the Microsoft loopback adapter hardware: 1. Click Start, enter "hdwwiz" in the Search box, and press Enter. 2. On the "Welcome to the Add Hardware Wizard - Welcome" page, click Next. 3. On the "Wizard can help you install other hardware" page, select "Install the hardware that I manually select from a list (Advanced)", and then click Next. 4. On the "From the list of hardware types" page, select Network adapters, and then click Next. 5. On the "Select Network Adapter" page, make the following selections, and then click Next: Manufacturer: Select Microsoft. Network Adapter: Select Microsoft Loopback Adapter. 6. On the "Wizard is ready to install your hardware" page, click Next. 7. On the "Completing the Add Hardware wizard" page, click Finish. 18 October, 2013, Rev. A 37

38 3 Installing a UNIFI Workstation To set up a connection to the Microsoft loopback adapter hardware: 1. From Control Panel, select Network and Sharing Center, and then click Change adapter settings. 2. Select the connection that was just created, which is usually named "Local Area Connection 2", and select Properties. 3. Select Internet Protocol (TCP/IPv4), and then click Properties. 4. In the Properties dialog box, verify that the options "Obtain an IP address automatically" and the "Obtain DNS server address automatically" are selected, click OK, and then close the dialog box. 5. Add a line to the DRIVE_LETTER:\WINDOWS\system32\drivers\etc\hosts file with the following format, after the localhost line: IP_address hostname.domainname hostname where is the non-routable IP address hostname is the name of the computer domainname is the name of the domain 6. Open a command prompt, and ping the computer using only the host name specified in the host file. Remove UNIFI software from a workstation Perform these operations when you want to remove UNIFI software from a workstation. If you want to update the software to a newer version, refer to the UNIFI Upgrade and Configuration Guide. Number Task Refer to this Help topic 1 Export all data folders. Rule: You must export data folders before you remove UNIFI software. If you do not export your data, the data will be irretrievably lost. Export data from UNIFI 2 Take all instrument systems offline. Modify device status 3 Physically disconnect instrument systems from the workstation to prevent re-detection. 4 Remove all instruments and then all instrument drivers. Delete devices October, 2013, Rev. A

39 Remove UNIFI software from a workstation Number Task Refer to this Help topic 5 Decommission and then delete all instrument systems. Requirement: If you have qualification results and maintenance logs for an instrument system, you must export the results and then delete them from the Qualification Center before you can delete the instrument system. 6 Deactivate all licenses. If you have installed and used Qualification licenses, contact Waters Technical Support to deactivate used Qualification licenses. 7 Close Portal. 8 Uninstall the previous version of UNIFI software in either of the following ways: Run the UNIFI installer again for the workstation. Open the Microsoft Windows Control Panel, and use the Programs and Features option to uninstall a program. Delete devices Activate and deactivate licenses 18 October, 2013, Rev. A 39

40 3 Installing a UNIFI Workstation October, 2013, Rev. A

41 4 Installing a UNIFI Workgroup Contents: Before you begin installing a workgroup server 41 Install UNIFI software on a workgroup server 45 Log on to the UNIFI portal 50 Activate UNIFI licenses 51 Create a new administrator account 53 Install UNIFI software on a client 55 Install UNIFI software on a laboratory network device 58 Automate database backups to a network location 63 Remove UNIFI software from a workgroup configuration 68 Before you begin installing a workgroup server Before you begin installing UNIFI software on a workgroup server, you must complete these tasks: Choose a database backup option. Configure disk drives. Create Windows application server role. Choose a database backup option When you install UNIFI software on a workgroup server, you must choose one of three backup options: Daily online (hot) backups Tip: If you choose online hot backups as your database backup option, you can recover database in the event of database failure, no data are lost. Daily offline (cold) backups No backups If you choose daily offline or online backups, the database backup runs automatically as a Windows scheduled task. You can modify the time in Windows Task Scheduler. Online hot backups If you select this option, these actions occur: A weekly full database backup plus daily incremental backups with archive log mode. Windows scheduled tasks named "At1" and "At2" are automatically created to back up the database. 18 October, 2013, Rev. A 41

42 4 Installing a UNIFI Workgroup "At1" scheduled task performs a full online database backup every Monday morning at 2:59 a.m. (you can modify this time). It runs immediately after installing the database for first time. "At2" scheduled task performs an incremental backup Tuesday through Sunday at 2:59 a.m. (you can modify this time). During database backups, the database is online and available for use (users can log on to the software and they can acquire data). When you select online hot backups as your database backup option, you can recover database in the event of database failure, no data are lost. Offline cold backups If you select this option, these actions occur: A full database backup occurs daily without archive log mode. A Windows scheduled task named "At1" is automatically created to back up the database every day at 2:59 a.m. (you can modify this time). During database backups, the database is offline and unavailable (users cannot log on to the software and they cannot acquire data). The amount of time it takes to back up the database depends on the size of the data (the larger the volume of data, the longer it takes to back up the database). When you select offline cold backups as your database backup option, you can recover the database up to the point of the last backup; data captured between backups is lost. Fast Recovery Area size If you chose online, hot backups during installation, the location for your database backups (FRA) must be able to accept data from two backups simultaneously: the software does not delete the obsolete backup until it confirms that the current one is completed. Online, hot backups also include archive logs. A database backup causes the software to generate a time-stamped log file that includes details about individual steps of the backup process. You can find this log file in this location: [install drive]:\waters\scripts\backuprecoveryscripts\logs October, 2013, Rev. A

43 Before you begin installing a workgroup server Retention of database backups UNIFI Backup and Recovery options: Option Description Recovery options Daily online (hot) backups Daily offline (cold) backup No backup A full online backup runs every Monday morning at 2:59 a.m. Incremental backups run Tuesday through Sunday at 2:59 a.m. A full offline backup runs every morning at 2:59 a.m. The database is not available during the backup process. The software does not install a backup option. You can fully recover the database. In the event of database failure, no data are lost because the data are backed up in archive logs between backups. You can recover the database to the point of the last backup. In the event of database failure, data captured since the last backup are lost. You are responsible for backing up and restoring the database. One full backup is kept in the Fast Recovery Area (FRA). Archive logs are removed when a new backup is made. When a new full database backup (level-0) is made, previous backups older than one week are removed from the FRA. To recover the entire database, you must generate a second backup of the workgroup server, and then archive the contents of the Fast Recovery Area (FRA) to a network share or storage array. The database is backed up and restored by using scripts that are installed on the workgroup server during installation. Only users with administrator and ora_dba privileges can backup and restore the database. When the database is backed up, it typically compresses approximately 50 % compared to its original size. Every time a database backup occurs, UNIFI software generates a log file that contains detailed information about the database backup process. The location of this log is: [install drive] waters\oracle\scripts\backuprecoveryscripts\logs. Configure disk drives Before you install UNIFI software on a workgroup server, you must configure one or three disk drives for Oracle Automatic Storage Management (ASM). If you are using external storage, you can configure one disk, but it must be at least a 500 GB drive. The disk groups that you create become the default location for the files created in the database. The disk group type determines how Oracle ASM mirrors files. An ASM disk can be a disk device. To configure disk drives for Oracle ASM: 1. From the Windows Start menu on the workgroup server, right-click Computer, and then select Manage. 2. From the Computer Management dialog box, click Storage > Disk Management. Important: Ensure all disks are online and unallocated. 18 October, 2013, Rev. A 43

44 4 Installing a UNIFI Workgroup Tip: If a disk is online and has a drive letter assigned to it, right-click on the disk, select Delete Disk, and then Delete Volume. Right-click on the disk and select Delete Partition. Disk Management: Create Windows application server role Before you install UNIFI software on a workgroup server, you must create a Windows application server role that automatically configures.net Framework Features and Microsoft Message Queue (MSMQ) Server. To create a Windows application server role: 1. On the workgroup server, open Server Manager from Administrative Tools. 2. Right-click Roles, and then select Add Roles. 3. In the Add Roles wizard, click Next. 4. In the Select Server Roles page, select Application Server, and then click Next. 5. In the Add Roles wizard, click "Add Required Features". 6. In the Select Server Roles page, click Next. 7. In the Application Server page, click Next. 8. In the Select Role Services page, select these services: TCP Port Sharing Message Queuing Activation Tip: When Windows prompts you to confirm your request for additional features or services, click "Add Required Features", and click Next. 9. In the Select Role Services page, select these services: October, 2013, Rev. A

45 Install UNIFI software on a workgroup server HTTP Activation TCP Activation Windows Process Activation Service Support Tip: When Windows prompts you to confirm your request for additional features or services, click "Add Required Features", and click Next. 10. In the Select Role Services page, select these services, and then click Next: Named Pipes Activation Web Server (IIS) Support Tip: When Windows prompts you to confirm your request for additional features or services, click "Add Required Features", and click Next. 11. In the Web server (IIS) page, click Next. 12. In the Select Role Services page, click Next. 13. In the Confirm Installation Selections page, confirm these selections, and then click Install. Confirm Installation Selections: Application Server.NET Framework Web Server (IIS) Support TCP Port Sharing Windows Process Activation Service Support HTTP Activation Message Queuing Activation TCP Activation Web Server (IIS) Web Server 14. In the Installation Results page, click Close. 15. On the Server Manager page, click Close. Install UNIFI software on a workgroup server Waters recommends a domain-based network infrastructure, though a UNIFI workgroup configuration does not require it. If the workgroup server is in a different domain than the clients or laboratory network devices, you must ensure that the date and time-stamps are synchronized with a time server. In a Windows Server 2008 R2-based domain, the domain controllers are automatically configured as time servers for the domain. Restriction: Do not install UNIFI software on the same machine as the domain controller. To maximize uptime and minimize issues related to the network environment, Waters recommends that you follow these guidelines: 18 October, 2013, Rev. A 45

46 4 Installing a UNIFI Workgroup Organize all UNIFI related accounts, computer and user, within the same domain. If you are using real-time virus scanning, exclude all UNIFI related folders and their subdirectories. Some real-time virus scanners mistake normal UNIFI software functionality for virus activity, causing data buffering problems. Configure preferences in Oracle Enterprise Manager to notify you by when disk space reaches a user-defined size. Doing so, helps you monitor database space usage. For more information, see the "Manage the server disk space" section in the UNIFI System Administrator's Guide. Important: After you install UNIFI software, do not change the IP address of the workgroup server. It is important that the workgroup server maintains a static IP address.changing either of these may render UNIFI software unusable. Before you begin Before you install UNIFI software on a workgroup server, configure these Windows settings: Verify Windows hosts file information Enable the correct option is enabled for Windows updates (not the "Install updates automatically" option). Configure network discovery and file and printer functions Configure the network LAN Confirm regional settings Identify location for database backup copies (if applicable) Verify Windows hosts file information Before you install UNIFI software on the workgroup server, you must verify that the Windows hosts file information contains the correct IP address and server host name for the workgroup server. To verify that the Windows hosts information is correct: 1. On the workgroup server, open the Windows hosts file (C:\Windows\System32\drivers\etc\hosts). 2. Verify that the file contains the correct IP address and the fully qualified domain name of the server. Tip: The fully qualified domain name of the server is required for OEM to install properly. Enable the correct option for Windows updates You must select the option "Check for updates, but let me choose whether to download them" for Windows updates October, 2013, Rev. A

47 Install UNIFI software on a workgroup server To specify the correct option for Windows updates on a client: 1. From Windows Control Panel, click "System and Security". 2. From the System and Security page, click "Windows Update". 3. From the Windows Update page, click "Change settings" page. 4. In the Important updates section of the Change Settings page, select "Check for updates, but let me choose whether to install them" option, and then click OK. Configure network discovery and file and printer settings On the workgroup server, you must enable the network discovery and the file and printer sharing functions so that clients can communicate with the server. To enable the network discovery on a server in a domain, you must start certain services. To start the required services on the workgroup server: 1. From Control panel, select Administrative Tools > Services. 2. Change the startup type to Automatic and start these services: DNS Client Function Discovery Resource Publication SSDP Discovery UPnP Device Host When all services are running, you can modify the network discovery settings on the server. To turn on the network discovery and file and printer sharing functions: 1. From the Start menu, open Control Panel > Network and Internet > Network and Sharing Center. 2. Click "Change advanced sharing settings", and turn on these functions: Network discovery File and printer sharing Configure the network LAN You must configure the power management settings for the server to turn off the power saving feature and clear the Internet Protocol version 6 options. To configure the network LAN settings: 1. Click Start > Control Panel > Network and Internet > Network and Sharing Center > View network status and tasks > Change adapter settings. 2. Right-click on Local Area Connection, select Rename, and type Instrument LAN. 3. Right-click on the instrument LAN, and then click Properties. Tip: If you are prompted for an administrator password or confirmation, type the password or provide the confirmation. 18 October, 2013, Rev. A 47

48 4 Installing a UNIFI Workgroup 4. On the Networking tab, click Configure. 5. On the Power Management tab, clear the "Allow the computer to turn off this device to save power" checkbox, and then click OK. 6. On the Networking tab, clear the Internet Protocol Version 6 (TCP/IPv6) checkbox. Confirm regional settings If you are installing UNIFI software on an English workstation, you must confirm that your Windows regional settings are configured for English (United States). The symbols for English (United States) use decimal, not comma formatting, which is important when displaying numeric values ("12.56", not "12,56"). To confirm that you have the correct regional settings: 1. From the Windows "Search programs and files" text box, type Regional Settings. 2. In the Region and Language dialog box, ensure "English (United States)" is selected as the format in the Formats tab. Identify location for database backup copies If you want to maintain a copy of your database backup external to the Oracle FRA location, you must identify a network storage device with sufficient space. Each time the database is backed up, a copy of the database backup is placed in this location. As a result, the storage space in this location diminishes quickly, and you must monitor the location to ensure that there is sufficient space to store the database backup copies. Requirement: You must be able to access this location from the workgroup server because you browse to the location when you install the software. Install UNIFI software on a workgroup server The Waters UNIFI installation wizard guides you through the installation process. Allow approximately 40 minutes to complete the installation. Requirement: You must have unrestricted local Windows administrator or equivalent privileges to install UNIFI v1.7 software. When you install UNIFI software on a workgroup server, the language installed is based on the workgroup server's operating system language. If the workgroup server's operating system is English, the software is installed in English. You cannot install the Japanese version of UNIFI software, on an English application server. See also: Before you install the workgroup server, refer to the UNIFI System Administrator's Guide to determine your database backup option and your company's redundancy options for Oracle ASM October, 2013, Rev. A

49 Install UNIFI software on a workgroup server To install the UNIFI software on a workgroup server: 1. Insert the UNIFI DVD into the computer's DVD drive. Tip: If the installer does not automatically start, open Window's Explorer, browse to the DVD drive, and double-click Setup.exe. 2. From the installation menu, click "Install UNIFI Workgroup Server". 3. On the "What do you want to install?" page, click "Install the UNIFI Application Server". 4. On the License Agreement page, read the agreement, click "I accept the terms of the license agreement", and then click Next. 5. On the Select an installation drive page, select the location UNIFI application software, and the Oracle database files. 6. On the Import Database page, select No if you are not importing the database or Yes to import the database, and then click Yes. 7. On the Oracle ASM drive selection page, select all the disks that you previously configured to use for Oracle ASM, select an ASM Redundancy, and then click Next. Tip: You can select one disk if you are using external redundancy, but it must be at least a 500 GB drive. If you previously selected one disk, the redundancy is automatically set to External. Redundancy options: Redundancy High Normal External Description 3-way mirroring. 2-way mirroring (for most files by default), two copies of every data extent. No mirroring by ASM and relies on the storage system to provide RAID functionality. 8. On the Database Backup Options page, select a database backup option, and then click Next. Daily backups without archive log mode. (A full offline backup runs every morning at 2:59 a.m. In the event of a database failure, data captured since the last backup are lost.) Weekly backups with a daily incremental with archive log mode. (A full offline backup runs every Monday morning at 2:59 a.m., and incremental backups run every morning. In the event of a database failure, no data are lost.) No database backup. (Not recommended.) 9. On the ASM Recovery Settings page, select a backup recovery option: "Skip backup recovery area". The database backup files are stored in the Oracle ASM DATA disk group. "Enable backup recovery area". The database backup files are stored in Oracle FRA (Flash Recovery Area) disk group. If you select only one disk, the 18 October, 2013, Rev. A 49

50 4 Installing a UNIFI Workgroup redundancy is external. Tips: You can select a maximum of 20 hard drives. You cannot select the system drive, installation drive, ASM drives, or formatted data drives. 10. On the Fast Recovery Area (FRA) Offline Storage Settings page, select whether you want to enable FRA offline storage to store copies of the database backups to offline storage. If you choose "Enable FRA Offline Storage", specify the location in which to store the copy of the database backups. Tip: If you choose "Enable FRA Offline Storage" and want to copy the database backups to a network location, you must perform this procedure "Automate database backups to a network location" after you install the software on the workgroup server. 11. On the UNIFI Application Server settings page, accept the defaults, and then click Next. 12. On the Configure UNIFI policy and audit trail settings page, perform one of these operations: To comply with GxP guidelines and regulations, click "Configure settings for a regulated environment (GxP)". To configure settings for a non-regulated environment, click "Configure settings for a non-regulated environment". See also: Appendix A for system policy and audit trail settings for a regulated and non-regulated environment. 13. On the Ready to Install page, click Install. 14. On the Installation Wizard Completed page, a message indicates whether the installation was successful, and you can click the link to open the Waters Installation Summary. If the software was not successfully installed, submit a request for Waters technical support at this Web address: To complete the installation, click Finish. Tip: If you close the installation wizard, and you want to open the installation log, browse to C:\Windows\WatersInstallationSummary. See also: For instructions on how to qualify the software, see the Workgroup Qualification Protocol which is available on the UNIFI Qualification media. For more information about qualification, refer to the "Qualification Overview" document on this media. Log on to the UNIFI portal After you install UNIFI, you must log on to the UNIFI portal to register the software and activate your licenses. Tip: When you restart the workgroup server, wait at least five minutes before logging on to UNIFI software, to allow time for Waters Service Host to restart October, 2013, Rev. A

51 Activate UNIFI licenses To log on to UNIFI: 1. On your desktop, double-click UNIFI Portal. 2. In the Login dialog box, type "administrator" in both the User name and Password fields. 3. On the Welcome page, click Administration, and then click Licensing, where you can register and activate product licenses. Activate UNIFI licenses Use the Waters Licensing Management System to activate or deactivate the purchased software's product licenses and options. Waters' licenses apply to a UNIFI system and user accounts. You can assign and revoke UNIFI named-user licenses to user accounts as needed. Workgroup license and options: License type System base UNIFI nameduser Instrument control Large molecule nameduser Small molecule nameduser Waters scientific library Required Yes Yes Yes No No No Definition Configures the database as a UNIFI workgroup. The base license includes no named-user licenses. You can activate a maximum of 10 named-user licenses to increase the number of users. Named-user licenses are required for users to log on to the software. One instrument control license is required for each online instrument system. If your instrument system includes a time of flight (TOF) mass spectrometer, this named-user license is required to perform Peptide Map and Intact Protein analysis and must be assigned to user accounts. If you want to process the data using the Dealkylation, MassFragment and IsoScore tools, this named-user license is required and must be assigned to user accounts. If you want to import a Waters scientific library, the appropriate library license is required. Tip: You can import and export your own scientific library. 18 October, 2013, Rev. A 51

52 4 Installing a UNIFI Workgroup Qualification licenses: License type Qualificationsoftware Qualificationinstrument Required for qualification Yes Yes Definition If you want to qualify the workgroup configuration, you must purchase a license for each device: workgroup server, laboratory network device, and client. To qualify instruments on a workgroup, you must activate these licenses: The UNIFI Instrument Qualification Module license is required for each LC instrument included in an instrument system. The UNIFI Instrument Qualification Standard Technology MS license is required for each Xevo TQ, Xevo TQD, Xevo TQ-S mass spectrometer. The UNIFI Instrument Qualification High Technology MS license is required for Xevo G2 TOF, Xevo G2 -S TOF, Xevo G2-S Q TOF mass spectrometers. The UNIFI Instrument Qualification Accessory license is required for each instrument accessory module. After you install UNIFI software, you must register, activate, and assign to users UNIFI named-user licenses by using the licensing wizard in UNIFI software and the Internet as follows: Create a software registration file using the licensing wizard. Submit the software registration file to the Waters License Activation Center Web site, and receive a license activation file. Activate your licenses and options using the licensing wizard and the license activation file. Register and activate licenses You must register and activate the UNIFI base license to access UNIFI software. You can activate licenses other than the base license at the same time or after activating the base license, but not before doing so. Pre-requisite: To complete the licensing process, you must have purchased UNIFI licenses from Waters and obtained a serial number for each purchased license. To register licenses: 1. On the Licensing Home page, click Register Software. 2. On the Request Software page, perform these operations, and then click Next: October, 2013, Rev. A

53 Create a new administrator account Type a new name for the software registration file, or allow the default name to remain unchanged. The names of all registration files must include the *.lic extension. Select the location of the license registration file. This file stores your license registration information. 3. When the Register Software page reappears, perform one of the actions in the following table, depending on whether your computer has Internet access. Internet access Yes No Action Click the hyperlink to connect to the Waters License Activation Center web site. Move the software registration file that you just created to a computer with Internet access and then access Follow the instructions to activate your licenses. After you receive the activation file, move the file to the computer on which UNIFI software is installed. 4. When you obtain a license activation file, return to the licensing home page, and click Activate Licenses. 5. On the Activate Licenses page, select the license activation file you downloaded from the Waters License Activation Center Web site, and then click Next. 6. On the Activate Licenses - License Activation Complete page, click Finish. Tips: View active licenses If you are activating the base license, log out and then log back on to UNIFI software to access the software's complete functionality. When you create an instrument system and bring it online, an instrument system license is automatically assigned it. You cannot bring instrument systems online if there are no instrument system licenses available. To view all activated licenses and available for deactivation, click Deactivate Licenses from the Licensing home page. The Deactivate License page displays a list of all activated licenses and options, as well as, unused qualification licenses. To view Qualification licenses, access the Qualification center (Qualification and Maintenance > Manage > Administration > Licenses). Create a new administrator account Administration > Security > Users > Create > User Editor 18 October, 2013, Rev. A 53

54 4 Installing a UNIFI Workgroup After you activate licenses, Waters recommends that you create a new administrator account, and disable the administrator account shipped with the software. In the event that your administrator account becomes locked, Waters provides a utility to unlock the default administrator account. See also: UNIFI System Administrator's Guide for information on the unlocking the default administrator account. To create a new administrator account and assign it a license: 1. Log on to UNIFI Portal and then click Administration. 2. From the Security area, click Users. 3. From the Global User List page, click Create. 4. In the Account Settings tab of the User Editor, enter the information for the administrator account. User settings: Option User Name First Name Last Name Assigned roles Default role Description Type a combination of your last name and first name. User account names must be unique. Because administrator is the default user name, you must type a user name other than "administrator", preferably a combination of your last and first name. Type your first name. Type your last name. Click System Administrator. Click Administrator. Tip: There is no need to enter a password for this account. The first time you log on to UNIFI software with this account, the password defaults to your username and you must change the password. 5. Click Save. 6. Click Administration, and then click Assign Licenses from the Licensing section. 7. On the Assign License page, assign to the new administrator account a license. Tip: When you assign a license, you do not need to confirm the action by clicking Save. After you create a new administrator account and assign it a license, you must revoke the license from the default administrator account, and then disable the user account October, 2013, Rev. A

55 Install UNIFI software on a client To revoke the administrator account license and then disable it: 1. Click Administration > Licensing > Assign Licenses. 2. On the Assign Licenses page, click "Administrator, UNIFI", and then right-click Revoke. Result: The number of available licenses increases by Click Administration > Security > Users. 4. From the Global User list, click administrator (UNIFI, administrator) user account, and then click Modify. 5. In the Account Settings tab of the User Editor, select Disabled from the Current Status field. 6. Click Save. See also: Activate UNIFI licenses Install UNIFI software on a client The Waters UNIFI installation wizard guides you through the installation process. Allow approximately 15 minutes to complete the installation. Recommendations: If you are using DHCP, reserve the IP address for the client. After you install UNIFI software on a client, do not change the IP address or computer name of the client. When you install UNIFI software on a client, the language installed is based on the client's operating system language. If the client's operating system is English, the software is installed in English. You cannot install the Japanese version of UNIFI software, on an English client. Before you begin Before you install UNIFI software on a client, configure these Windows settings: Turn on Microsoft Message Queue (MSMQ) server Configure the power options Turn on the network discovery and file and printer settings Ensure the correct option is enabled for Windows updates (not the "Install updates automatically" option). Verify connectivity between client and workgroup server Turn on MSMQ Server Before you install UNIFI software on a client, you must turn on MSMQ Server. 18 October, 2013, Rev. A 55

56 4 Installing a UNIFI Workgroup To turn on MSMQ: 1. Click Start > Control Panel > Programs > Programs and Features. 2. Click the option to "Turn Windows features on or off". 3. In the Windows Features dialog box, expand Microsoft Message Queue (MSMQ) Server, and then expand Microsoft Message Queue (MSMQ) Server Core. 4. Select MSMQ HTTP Support and MSMQ Triggers. Tip: Do not select MSMQ Active Directory Domain Services Integration and Multicasting Support. 5. Click OK, and then wait while the features are configured. Configure the power options You must configure the power management settings for the client to turn off the power saving feature. To configure the power options: 1. From Windows Control Panel, click System and Security, and then Power Options. Alternate: From the Search Programs and Files, type Power Options. 2. On the Power Options page, click Show additional plans, select High performance, and then click "Change plan settings". 3. On the Edit Plan Settings page, perform these tasks, and then click Save changes: Select Never from the "Turn off the display" field. Select Never from the "Put the computer to sleep" field. 4. On the Edit Plan Settings page, click "Change advanced power settings". 5. In the Power Options dialog box, complete these tasks, and then click OK. Client power option settings: Power options Expand Hard Disk and "Turn off hard disk after" Expand Sleep settings: Sleep after Allow hybrid sleep Hibernate after Allow wake timers Expand USB settings and "USB selective suspend" Expand Display and "Turn display after" Setting Type Never in the Setting(Minutes) field Never Off Never Disable Disabled Never October, 2013, Rev. A

57 Install UNIFI software on a client Turn on network discovery and file and printer sharing settings Enable the Windows network discovery and file and printer sharing settings on the client. To turn on Windows network discovery and file and printer sharing settings: 1. From Windows Control Panel, click "Network and Internet". 2. From the Network and Internet page, click "Network and Sharing Center". 3. From the Network and Sharing Center page, click "Change advanced sharing settings". 4. From the Change sharing options for different network profiles, expand one of the profiles, and then make these selections: From Network discovery, click "Turn on network discovery". From File and printer sharing, click "Turn on File and printer sharing". 5. Click Save changes. Enable the correct option for Windows updates You must select the "Check for updates, but let me choose whether to download them" option for Windows updates. Ensure that the "Automatic updates" option is disabled. To specify the correct option for Windows updates on a client: 1. From Windows Control Panel, click "System and Security". 2. From the System and Security page, click "Windows Update". 3. From the Windows Update page, click "Change settings" page. 4. In the Important updates section of the Change Settings page, select "Check for updates, but let me choose whether to install them" option, and then click OK. Verify connectivity between the client and workgroup server Before you install UNIFI software on a client, ensure it can connect to the workgroup server by pinging the server. To ping the workgroup server: 1. From Windows' Explorer "Search programs and files", type Run, and press Enter. 2. In the Run dialog box, type cmd.exe. 3. In the Command prompt window, type ping <IP Address>, where IP Address is the IP address of the server. Install UNIFI software on a client You can install UNIFI software on client from the product DVD. 18 October, 2013, Rev. A 57

58 4 Installing a UNIFI Workgroup Install UNIFI software from the product DVD Requirement: You must have Windows administrator privileges to install UNIFI v1.7 software. To install the UNIFI software on a client computer: 1. Insert the UNIFI DVD into your computer's DVD drive. Tip: If the installer does not automatically start, open Window's Explorer, browse to the DVD drive, and double-click Setup.exe. 2. From the installation menu, click Install UNIFI Workgroup server. 3. On the "What do you want to install?" page, click "Install the UNIFI client". 4. On the License Agreement page, read the agreement, click "I accept the terms of the license agreement", and then click Next. 5. On the Select an installation drive page, perform one of the following tasks: Click Next to install the software on the C drive. Select a drive other than C to install the software on a different drive. 6. On the UNIFI Application Server Settings page, type the name or IP address of the workgroup server, and then click Next. 7. On the Ready to install page, click Install. 8. On the Installation Wizard Complete page, click Finish. Tip: If the verification failed, click the link to open the installation log file. If the software was not successfully installed, submit a request for Waters technical support at this web address: If you close the installation wizard and you want to open the installation log, browse to C:\Windows\WatersInstallationSummary. After you install UNIFI software on a client After you install UNIFI software on a client, you can install a UNIFY print driver; however, you must install UNIFI software first and then the UNIFY print driver. For instructions on how to install the UNIFY print driver, see the NuGenesis 8 Installation and Configuration Guide. Install UNIFI software on a laboratory network device Laboratory Network Devices (LNDs) control and collect data acquired from connected instrument systems. You can purchase one from Waters Corporation, or you can configure a custom LND. Waters recommends that you purchase an LND that is pre-configured to work with UNIFI software. When you install UNIFI software on an LND, the language installed is based on the LND's operating system language. If the LND's operating system is English, the software is installed in English. You cannot install the Japanese version of UNIFI software, on an English LND October, 2013, Rev. A

59 Install UNIFI software on a laboratory network device Recommendations: After you install UNIFI software on an LND, Waters recommends that you do not change the IP address or computer name of the LND. If you are using DHCP, Waters recommends that you reserve the IP address for the LND. If you are using real-time virus scanning, exclude all UNIFI related folders and their subdirectories. Some real-time virus scanners mistake normal UNIFI software functionality for virus activity, causing data buffering problems. Before you begin If you install UNIFI software on a Waters laboratory network device, ensure the correct option is enabled for Windows updates (not the "Install updates automatically" option). Install UNIFI software on a custom laboratory network device If you install UNIFI LND software on a computer other than the Waters UNIFI Laboratory Network Device, you must perform these tasks: Ensure the correct option is enabled for Windows updates (not the "Install updates automatically" option). If you are using real-time virus scanning, exclude all UNIFI related folders and their subdirectories. Some real-time virus scanners mistake normal UNIFI software functionality for virus activity, causing data buffering problems. Turn on the network discovery function and file and printer sharing function. Turn on MSMQ server. Configure the power options. Configure the instrument LAN. Configure the Windows firewall settings. Enable the correct option for Windows updates You must select the option "Check for updates, but let me choose whether to download them" for Windows updates. To specify the correct option for Windows updates on a client: 1. From Windows Control Panel, click "System and Security". 2. From the System and Security page, click "Windows Update". 3. From the Windows Update page, click "Change settings" page. 4. In the Important updates section of the Change Settings page, select "Check for updates, but let me choose whether to install them" option, and then click OK. 18 October, 2013, Rev. A 59

60 4 Installing a UNIFI Workgroup Turn on network discovery and file and printer sharing settings Enable the Windows network discovery and file and printer sharing settings on the laboratory network device. To turn on Windows network discovery and file and printer sharing settings: 1. From Windows Control Panel, click "Network and Internet". 2. From the Network and Internet page, click "Network and Sharing Center". 3. From the Network and Sharing Center page, click "Change advanced sharing settings". 4. From the Change sharing options for different network profiles, expand one of the profiles, and then make these selections: From Network discovery, click "Turn on network discovery". From File and printer sharing, click "Turn on File and printer sharing". 5. Click Save changes. Turn on the Microsoft Message Queue Server Before you install UNIFI software on a computer other than the Waters UNIFI Laboratory Network Device, you must turn on the MSMQ server. To turn on the server: 1. Click Start > Control Panel > Programs > Programs and Features. 2. Click the option "Turn Windows features on or off". 3. In the Windows Features dialog box, expand Microsoft Message Queue (MSMQ) Server, and then expand Microsoft Message Queue (MSMQ) Server Core. 4. Select MSMQ HTTP Support and MSMQ Triggers. Tip: Do not select MSMQ Active Directory Domain Services Integration and Multicasting Support. 5. Click OK, and then wait while the features are configured. Configure the power options You must configure the power management settings for the LND to turn off the power saving feature. To configure the power options: 1. From Windows Control Panel, click System and Security and then Power Options. Alternate: From the Search Programs and Files, type Power Options. 2. On the Power Options page, click Show additional plans, select High performance, and then click "Change plan settings". 3. On the Edit Plan Settings page, perform these tasks, and then click Save changes: October, 2013, Rev. A

61 Install UNIFI software on a laboratory network device Select Never from the "Turn off the display" field. Select Never from the "Put the computer to sleep" field. 4. On the Edit Plan Settings page, click "Change advanced power settings". 5. In the Power Options dialog box, do the following tasks, and then click OK. LND power option settings: Power options Expand Hard Disk and "Turn off hard disk after" Expand Sleep settings: Sleep after Allow hybrid sleep Hibernate after Allow wake timers Expand USB settings and "USB selective suspend" Expand Display and "Turn display after" Setting Type Never in the Setting(Minutes) field Never Off Never Disable Disabled Never Configure the Instrument LAN You must configure the power management settings and assign the IP address for the Instrument LAN to communicate with the instruments. Log on to the LND as the local administrator. Configure the power management settings Configure IP address To configure the power management settings: 1. Click Start > Control Panel > Network and Internet > Network and Sharing Center > View network status and tasks > Change adapter settings. 2. Right-click Instrument LAN, and then click Properties. If you are instructed to enter an administrator password or confirmation, do so. 3. On the Networking tab, click Configure. 4. On the Power Management tab, clear the "Allow the computer to turn off this device to save power" checkbox, and then click OK. To configure the IP address: 1. Click Start > Control Panel > Network and Internet > Network and Sharing Center > View network status and tasks > Change adapter settings. 2. Right-click Local Area Connection, Instrument LAN, and then click Properties. 3. On the Networking tab, clear the Internet Protocol Version 6 (TCP/IPv6) checkbox. 18 October, 2013, Rev. A 61

62 4 Installing a UNIFI Workgroup 4. Select Internet Protocol Version 4 (TCP/IPv4), and then click Properties. 5. In the Internet Protocol Version 4 (TCP/IPv4) Properties dialog box, click "Use the following IP address". 6. Assign the following IP address and Subnet mask, and then click OK: IP address: Subnet mask: Result: The assigned setting is saved for the local area connection, instrument LAN. Configure the Windows firewall settings For a laboratory network device, you must configure Windows firewall settings to turn off the Windows firewall for the Instrument LAN (public network). Tip: For the instruments to communicate with the LND, you must configure the LND's Windows firewall settings. To configure the Windows firewall settings: 1. Click Start > Control Panel > Network and Internet > Network and Sharing Center > Windows Firewall. Alternative: Right-click Network from the desktop and then select Properties > Windows Firewall. 2. On the Windows Firewall page, click "Turn Windows Firewall on or off". 3. On the Customize Settings page, perform these tasks, and then click OK: Click "Turn on Windows Firewall" for the "Home or work (private) location settings". Click "Turn off Windows Firewall (not recommended)" for the "Public network location settings". Install UNIFI software on a laboratory network device The Waters UNIFI installation wizard guides you through the installation process. You should allow approximately 30 minutes to complete the installation. Requirement: You must have administrator privileges to install UNIFI v1.7 software. To install the UNIFI software on a laboratory network device: 1. Insert the UNIFI DVD into your computer's DVD drive. Tip: If the installer does not automatically start, open Window's Explorer, browse to the DVD drive, and double-click Setup.exe. 2. From the installation menu, click "Install UNIFI Workgroup server". 3. On the "What do you want to install?" page, click "Install the UNIFI laboratory network device". 4. On the License Agreement page, read the agreement, click "I accept the terms of the October, 2013, Rev. A

63 Automate database backups to a network location license agreement", and then click Next. 5. On the Select an installation drive page, perform one of these operations: Click Next to install the software on the C drive. Select a drive other than C to install the software on a different drive. 6. On the UNIFI Application Server settings page, type the name or IP address of the workgroup server, and then click Next. 7. On the UNIFI Database Settings page, click Next. 8. On the Ready to install page, click Install. 9. On the Installation Wizard Completed page, click Finish. Tip: If the verification fails, click the link to open the installation log. If the software was not successfully installed, submit a request for Waters technical support at this web address: If you close the installation wizard and you want to open the installation log, browse to C:\Windows\WatersInstallationSummary. Automate database backups to a network location If you chose "Enable FRA Offline Storage" during software installation and want to automate the copying of database backups to a network location, you must modify the OracleServiceUNIFI and the OracleASM Listener services to include a named user account. The named user account can be local user account or domain user account. The domain user account is always referred as <domain name\user account>. Tip: This procedure documents how to automate the copying of the database backups to a network location. It does not include data moved to an offline location by an offline storage management system. To copy database backups to a network location using a named user account, you must perform these tasks: Create an OS or domain user account with the correct permissions Create a network share for stored database backups and provide access to the OS or domain user account Add credentials to access the network share to automatically access the network Create the OracleCRSToken Service and then manually set the password Stop the database and Oracle listener Stop Oracles services, if necessary, and then specify that services can run with a local or domain user account Grant permission to the named user to use the Oracle resources Start services Start the database and then restart the server Verify backups are copied to network location by running the At1 or At2 database backup scheduled tasks 18 October, 2013, Rev. A 63

64 4 Installing a UNIFI Workgroup Create an OS user account with the correct permissions The user can be a domain user or a local user. If the user is on a different domain than the server, a trust relationship must exist between the two domains. If you want to use a domain user account, you may want to create a new one, because this account's password will never expire and cannot be changed. You must exempt this domain user account from any policies that require password changes. Requirement: The user must be part of the ORA_DBA and the local Administrators group. Create local user accounts To create an OS user on the local server with the correct permissions: 1. On the server, open Server Manager. 2. In the Server Manager window, expand Configuration > Local Users and Groups. 3. Click Action, and then New User. 4. In the New Action User dialog box, perform these tasks, and then click OK: Type the Full name and description of the user. Select these password settings: "User cannot change password" and "Password never expires". 5. Right-click the user you just created, and then select Properties. 6. In the Properties dialog box, select the Member Of tab, click Add to add the "Administrators" and "ora_dba" groups to this user account. Create domain user accounts If you are using a domain account, you must add the domain account to the local "Administrators" and "ora_dba" group. To add domain account to required groups: 1. On the local server, open Server Manager. 2. In the Server Manager window, expand Configuration > Local Users and Groups > Groups. 3. Right-click on Administrators group > Properties. 4. In the Administrator s properties dialog box, click Add. 5. in the Select Users, computers, service accounts, or groups dialog box, type <domain\username> in the "Enter the objects name to select" text box. 6. Click OK. 7. When prompted enter a user account and password for an account that contains the privilege to add to the group. Create a network share to store database backups To store database backups on a network share, you must perform these tasks: October, 2013, Rev. A

65 Automate database backups to a network location Identify the directory to store the database backups. Create a network share. Grant permissions to the local or domain user account to this network share. To identify a database backup directory and create a network share: 1. Locate a directory to store the database backups. 2. Right-click Properties on the directory you are going to share. 3. On the Properties dialog box, click the Sharing tab, and then click Advanced Sharing. 4. In the Advanced Sharing dialog box, perform these tasks: Click Share this folder. Enter the share name (typically OfflineBackup$, but you can change the share name to anything you want). Click Permissions. 5. On the Share Permissions tab, click Add, type the domain or local user account in the "Enter the object names to select" text box, and then click OK. 6. On the Share Permissions tab, select your OS or domain user account, and then click Full Control. 7. Click Apply, and then click OK. 8. On the Advanced Sharing tab, click OK. To grant permissions to the local or domain user account to this network share: 1. On the Properties dialog box, click the Security tab, and then Advanced. 2. On the Advanced Security settings page, click Change Permissions, and then click Add. 3. In the Select, User, computer, Service Account, or Group dialog box, type the domain or local user account in the "Enter the object name to select" text box and then click OK. 4. In the Permission Entry dialog box, click Allow Full Control, and then click OK. 5. In the Permissions tab of the Advanced Security Settings dialog box, click OK. 6. In the Security tab, click close. Add credentials to automatically access the network share You can add the credentials of the domain or local user account to automatically access the network share. To add the credentials to automatically access the network share: 1. From Control Panel > User Accounts > Credential Manager, click Add a Windows Credential. 2. In the Add a Windows Credential page, perform these tasks, and then click OK: 18 October, 2013, Rev. A 65

66 4 Installing a UNIFI Workgroup Type the computer name of where the network share resides in the "Internet or network address" text box. Type the <domain name\ user account> in the User Name text box. Type the password for this account. Result: The name of the network computer appears in the list under Windows Credentials. Create the OracleCRSToken Service and then manually set the password This service, also known as OSTS, simplifies access control and identity propagation across heterogeneous platforms. See: Oracle Security Token Service 11gR2 document from Oracle. To create the OracleCRSToken Service: 1. From the server, open a command prompt, and then type this command: Set Oracle_home= C:\Waters\oracle\asm Type crsuser add <domainname>\<username> Tip: For a local user, specify the nodename\username 2. When prompted for the password, press [Enter] to leave the password blank. Example: C:\waters\oracle\asm\cruser add devtest\orauser Enter the password for oracle domain\oracluster: [Press Enter]. To manually set the password for the OracleCRSToken Service: 1. On the server, open Server Manager. 2. Open services, right-click the OracleCRSToken service, and then select Properties. 3. In the OracleCRSTokenService dialog box, perform on these tasks: On the Log On tab, locate the OS user account you just created, and then type and confirm this user's password. On the General tab, set the Startup Type to Automatic, and then start the service. Stop the database and Oracle listener You must stop the database and then Oracle listener. To stop the database and Oracle listener: 1. From the server, open a command prompt. 2. From the Command window, change the directory to C:\Waters\Oracle\ASM and then type these commands: C:\Waters\oracle\ASM>srvctl stop database -d <database name> C:\Waters\oracle\ASM>srvctl stop listener October, 2013, Rev. A

67 Automate database backups to a network location Tip: The default <database name> is UNIFI. Stop services Confirm that the OracleServiceUNIFI and OracleASMTNSListener services are stopped. If for some reason these service are not stopped, you must stop them by using the Windows Manage Services feature. You must also set the services to run with the domain or local user account. To specify that the Oracle services can run with the domain or local user account: 1. For the OracleServiceUNIFI service and OracleASMTNSListener service right-click Properties. 2. In the Properties dialog box, select the Log On tab, and then select the option to log on as "This account" and type the local or domain user account and password in the "This account" box. Important: Do not browse to select the user account, you must type the domain\user account or local user account and password in the "This account" text box. Grant permissions to the named user You must grant permissions to the local or domain user account that you previously created to use Oracle resources. From the server, open a command prompt, change the directory to C:\Waters\oracle\ASM\BIN, and then type these commands: Start services C:\Waters\oracle\ASM\BIN>crsctl setperm resource ora.listener.lsnr-o <domain name>\user account C:\Waters\oracle\ASM\BIN>crsctl setperm resource ora.unifi.db -o<domain name>\user account You must start these services on the server: OracleASMTNSListenener and OracleServiceUNIFI. To start the services: 1. On the server, open Server Manager. 2. Open services, right-click the OracleServiceUNIFI and OracleASMTNSListener services, and select Start. Modify the database backup tasks to run as the local or domain user account You must modify the database backups tasks (At1 and At2) to run as the local or domain user account. 18 October, 2013, Rev. A 67

68 4 Installing a UNIFI Workgroup To modify the database tasks: 1. In Task Scheduler, open the Task Scheduler library. 2. Right-click At1 and select Properties. 3. In the General tab of the At1 Properties dialog box, select "Windows Vista, Windows Server2008" in the Configure for text, and then click "Change User or Group". 4. In the Select User or Group dialog box, type the <domain name\user account> in the "Enter the object name to select" text box, and then click OK. 5. In the Windows Security dialog box, type the user name and password of the domain or local account that has permissions to change the scheduled tasks on the local server, and then click OK. 6. When prompted type the password for the local or domain user account and then click OK. 7. Repeat all previous steps for At2 scheduled task. Start the database and then restart the server You must restart the database first to ensure that all the services are back online and then restart the server to refresh the environment. To restart the database, open a command prompt from the server, and type the following: C:\Waters\oracle\ASM\>srvctl start database -d <database name>. Restart the server. Verify backups are copied to network location You can verify that the database backups will be copied to the network location by manually running the At1 or At2 scheduled task. To manually run the database backup tasks: 1. In Task Scheduler, open the Task Scheduler library. 2. Right-click At1 or At2 and select Run. Once completed, verify that the network share contains the database backup. To verify that the task is completed, click Actions > Display All Running Tasks in the Task Scheduler window. Tip: If you didn't enable FRA Offline Storage during installation, you must edit the scheduled tasks for both hot and cold backups as outlined in the "Archive database backups" section of the UNIFI System Administrator's guide. Remove UNIFI software from a workgroup configuration When you must remove UNIFI software from a workgroup configuration, perform these operations in sequence: October, 2013, Rev. A

69 Remove UNIFI software from a workgroup configuration Number Task Refer to this Help topic 1 Export all data folders. Rule: You must export data folders before you remove UNIFI software. If you do not export your data, the data will be irretrievably lost. Export data from UNIFI 2 Take all instrument systems offline. Modify device status 3 Physically disconnect instrument systems from laboratory network devices, to prevent re-detection. 4 Decommission and then delete all instrument systems. Requirement: If you have qualification results for an instrument system, you must export the results and then delete them from the Qualification Center before you can delete the instrument system. Delete devices 5 Remove all instruments and then all instrument drivers. Delete devices 6 Change the status of all laboratory network devices from online to offline, and then to decommissioned. Important: Once decommissioned, do not restart laboratory network devices because they will re-register on the workgroup server. 7 Change the status of clients from online to decommissioned. Important: Once decommissioned, do not restart the clients because they will re-register on the workgroup server. 8 Deactivate all licenses from the workgroup server. If you installed and used Qualification licenses, contact Waters Technical Support to deactivate used Qualification licenses. 9 Close Portal. 10 Uninstall UNIFI software in either of these ways: Run the UNIFI installation wizard again for each of these devices: client, laboratory network device, and workgroup server. Open the Microsoft Windows Control Panel, and user the Programs and Features option to uninstall a program. Modify device status Modify device status Activate and deactivate licenses 18 October, 2013, Rev. A 69

70 4 Installing a UNIFI Workgroup October, 2013, Rev. A

71 5 Managing the Database Contents: Back up the workstation database 71 Restore the workstation database 73 Back up the workstation database You can back up and restore the UNIFI workstation database using the following Backup and Restore scripts located in this folder: <installation_directory>:\waters\oracle\scripts\backuprecoverscripts. Workstation Scripts Backup.bat Rmanwarchlv0.cmd Rmanwarch.cmd Purpose Performs a cold full backup of the database. Performs a hot full backup of the database. Performs a hot incremental backup of the database. Important: Make a copy of the BackupRecoverScripts folder, and put the copy in a secure location, retaining the original folder in the event you modify the backup scripts. Before you back up the workstation database Before you back up the UNIFI workstation database, complete these tasks: Confirm that the instrument system is idle. Ensure all Portal sessions are closed. Windows user groups When you install UNIFI software on a workstation, two user groups are automatically created: UNIFI operators and ora_dba. Do not modify or delete these user groups. The UNIFI operators group includes services that are required for UNIFI software to function properly. The ora_dba group is created by Oracle and automatically includes the user name of the administrator who installs UNIFI software. Users who belong to this group can log on to the database locally and perform SYSDBA functions. Requirement: You must be a member of the ORA_DBA group on this workstation to perform a database backup. 18 October, 2013, Rev. A 71

72 5 Managing the Database Back up database to default location You can back up the database to the default location <installation drive>:\waters \oracle\- fast_recovery_area or to a specified location. To back up the UNIFI database: 1. From the Windows Start menu, type cmd in the Search programs and files. 2. Right-click cmd.exe, and then select Run as Administrator. 3. From within the command window, at the command prompt, type the following command to change directories: cd C:\ <installation_drive>:\waters\oracle\scripts\backuprecoveryscripts 4. At the command prompt, type the following command "backup". Result: The backup script runs in verbose mode, so that you can view its progress. Important: When the backup process finishes, the command prompt appears, ready to receive another command. To view the backup log file: 1. Open Windows Explorer, and navigate to this file system location: <installation_drive>:\waters > Oracle > Scripts > BackupRecoverScripts > logs Tip: The backup script creates the log file using the following naming convention: MonthDayYearHourMin.log: for example, May log. 2. To view the log file content, open it in Notepad or another text editor. Back up database to a specified location You can back up the database to a specified location by editing the rmanbackup file. To edit the rmanbackup file: 1. Open Windows Explorer, and navigate to this file system location: <InstallationDirectory>:\Waters > Oracle > Scripts > BackupRecoverScripts. 2. Select rmandbackup and the right-click Edit. 3. In Notepad, after db_recovery_file_dest_size command, type this new command: SQL 'alter system set db_recovery_file_dest="<location>" scope=both'; Where location is the backup location (for example: D:\Backup) October, 2013, Rev. A

73 Restore the workstation database 4. Click Save and then close Notepad. 5. Run the Backup.bat file. Result: A database backup is created in the location you specified. Managing backup-related files The Waters UNIFI workstation backup process keeps only the last two backups in the AUTORECOVERY and BACKUPSET folders. When you complete a third backup, the latest version (by date) backup is deleted. The backup process creates and stores backup-related files in the following folders in the installation directory: <installation_directory>waters > ORACLE > FLASH_RECOVERY_AREA > UNIFI folder AUTOBACKUP folder includes a sub-folder named Year_Month_Day: for example, 2011_05_02. This folder contains a *.BKP file, which contains a backup of your control files. BACKUPSET folder includes a sub-folder named Year_Month_Day. This folder contains a *.BKP file, which contains a backup of your database data files and table spaces. Recommendation: Periodically back up the WatServiceHost logs and the portal folders contained in the C:\ProgramData\Waters\Logs folder. To back up the WatServiceHost logs and portal folders: 1. From within a Windows Explorer window, show hidden folders. 2. Navigate to the C:\ProgramData folder, to view its content. 3. In the ProgramData folder > Waters > Logs folder, copy the oldest WatServiceHost logs and portal files into another folder to save as backup. 4. In the ProgramData > Waters > Logs folder, delete the oldest files, and keep only the newest files. Requirement: Do not delete these files: Waters.Deployment.InstallUtil.exe.log Waters.UdfTypeScannerlog DetectInstrument.log Restore the workstation database You can back up and restore the UNIFI workstation database using the following Backup and Restore scripts located in this folder: <installation_directory>:\waters\oracle\scripts\backuprecoverscripts. 18 October, 2013, Rev. A 73

74 5 Managing the Database Workstation Scripts Backup.bat Purpose Cold backup of the database and calls RManBackup.cmd which performs a full backup. Rmanwarchlv0.cmd Performs a hot full backup of the database. Rmanwarch.cmd EXECLOG Performs a hot incremental backup of the database. Called in the RestoreDB.bat script. When you restore the workstation database, it is recovered to the last backup only. No recovery occurs from REDO logs because the restore scripts contain a "noredo" option. Tip: It is important that the computer name and IP address remain the same for the database restoration process to work correctly. If you are replacing the workstation with a new computer, you cannot restore the database on a new workstation with a different computer name and IP address. Before you restore the workstation database Before you restore the UNIFI workstation database, you must complete these tasks: Confirm that the instrument system is in an idle state. Close the UNIFI portal. Verify your Oracle sys account password and your Oracle SID because they are required to run the scripts. The default Oracle SID is UNIFI. Verify your database ID. You can find the database ID in the backup.log.files. To restore the UNIFI workstation database: 1. From the Windows Start menu, type cmd in the Search programs and files. 2. Right-click cmd.exe, and then select Run as Administrator. 3. In a command window, at the command prompt, type the following command line to change directories: cd <installation_directory>:\waters\oracle\scripts\backuprecoveryscripts 4. At the command prompt, type the following command, followed by your Oracle SID and your Oracle sys password: restoredb.bat <Oracle SID> <your_oracle_sys_password><database ID> Example: C:\ RestoreDB.bat UNIFI Oracle See also: UNIFI System Administrator's Guide, "Record database information" for instructions on how to find the database ID. The database ID may be recorded on the Change information page in UNIFI software. To access this page, log on to Portal and then click Administration. From the Administration page, click Software Management and then UNIFI information. Rule: The Restore script does not run in verbose mode. Depending on the size of your database, the restoration process can require several minutes October, 2013, Rev. A

75 Restore the workstation database Important: The restoration process replaces all data files, control files, and table spaces from the most recent backup. It does not restore changes made after your last backup. Any changes made since the last backup will be lost. When the restoration process ends, the command prompt appears, ready to receive another command. To view the restore log: 1. Open Windows Explorer, and navigate to the this folder: <InstallationDirectory>Waters > Oracle > Scripts > BackupRecoverScripts folder. 2. To view the content of the restore.log file, open it in Notepad or another text editor. Tip: Each time you restore the database, the restoration process appends additional information to the restore.log file. Restore database from a specified location If you backed up the database from a specified location, rather than the default location (C:\Waters \oracle\fast_recovery_area), you must modify the DBRestoreWKSN.sql file to change the database recovery file destination location. To modify the DBRestoreWKSN sql file: 1. Open the DBRestoreWKSN sql file in Notepad. 2. Update the db_recovery_file_dest = '<new specified location>' in two places in this file. Where <new specified location> is the database backup location (for example: D:\Backup). 18 October, 2013, Rev. A 75

76 5 Managing the Database October, 2013, Rev. A

77 6 Verifying the installation Contents: Verify installed files on a workstation 77 Verify installed files for a workgroup 78 Verify installed files on a workstation After you install the UNIFI software and licenses, you can generate a Verify Files report. To generate the Verify Files report: 1. Click Administration > Qualification and Maintenance. 2. On the Qualification and Maintenance page, select Qualify > Qualify Software. 3. Select the workstation, and then click "Execute Verify Files for selected line". 4. In the Configuration pane, select the History tab, and then click "Verify files report" or the "Extended Verify files report" link to open the report. Tip: You can view and print two versions of the Verify files report: the Verify files report and the Extended Verify files report. The Verify files report lists the checksums at the folder level and the Extended Verify files report lists all files for all folders that are checked and verified during installation. The difference between these two reports is approximately 50 pages. 18 October, 2013, Rev. A 77

78 6 Verifying the installation Verify files report example: Verify installed files for a workgroup After you install the UNIFI software and licenses, you can generate a Verify Files report for each device that comprises a workgroup configuration. Tip: The Verify Files report can require several minutes to generate. To generate the Verify Files report: 1. Click Administration > Qualification and Maintenance. 2. On the Qualification and Maintenance page, select Qualify > Qualify Software. 3. On the Qualify Software page, select Clients, Laboratory Network Devices, or Workgroup Servers, and then click the "Execute Verify Files for selected line" icon October, 2013, Rev. A

79 Verify installed files for a workgroup Tip: To select multiple LNDs and clients, press [Shift] and left-click. Qualify Software: 4. In the Configuration pane, select History tab, and then click the "Verify files report" or "Extended Verify files report" link to open the report. Tip: You can view and print two versions of the Verify files report: the Verify files report and the Extended Verify files report. The Verify files report lists the checksums at the folder level and the Extended Verify files report lists all files for all folders that are checked and verified during installation. The difference between these two reports is approximately 50 pages. 18 October, 2013, Rev. A 79

80 6 Verifying the installation The Verify Files report displays in the Report Viewer page. You can print this report October, 2013, Rev. A

81 7 Troubleshooting Contents: Record a problem 81 UNIFI Installation troubleshooting 81 Record a problem Start > Search programs and files > Problem Steps Recorder To record your interactions with a software application when it encounters a problem, use the Microsoft Windows 7 utility called Problem Steps Recorder. The utility records the problem by creating step-by-step screen captures enhanced with descriptive text. It then saves the screen captures and text to a zip file, which you can to experts for troubleshooting. To record a problem: 1. Click Start, and in the "Search programs and files" text box, type Problem Steps Recorder. 2. Click Start Record, and perform the actions that produce the problem. Tips: To pause the recorder, select Pause Record. To add a comment to the record, select the area of the window that you want to comment on, and then click Add Comment. 3. Click Stop Record. 4. In the Save As dialog box, type a name for the zip file, and then specify its location. UNIFI Installation troubleshooting This chapter provides solutions to problems you can encounter while installing the UNIFI software. It describes possible symptoms and corrective actions. 18 October, 2013, Rev. A 81

82 7 Troubleshooting Problem Symptom Solution Cannot log on to UNIFI software using the administrator account from a workstation or a workgroup server. Tip: You cannot check Waters Service Host from a client computer. Cannot import files from other applications into UNIFI software. Cannot log on to UNIFI portal using a client computer. Cannot log on to UNIFI portal using a client computer. The error message: Cannot find Service appears. The Waters UNIFI Printer does not appear in the Windows printer list. This error message appears: "This UNIFI client is not registered or it was decommissioned. Please use a valid one or contact your system administrator". The error message appears: "Portal session closed because the application server was offline or unavailable". Verify that the Waters Service Host is started: 1. Right-click My Computer. 2. Click Services and Applications > Services. 3. In the Services area, select Waters Service Host, and verify the status is Started, and the Startup Type is set to Automatic (delayed start). If the service is not started, click Start or Restart the service. If you did not install the Waters UNIFI printer when you installed UNIFI software, you cannot import files from other applications into UNIFI software. If you want to import files from other applications into UNIFI software, you must install the components required to import these two file types: Reports: Waters UNIFI printer Data files: Waters internal printer queue Restart Waters Client services: 1. From the Start menu, right-click My Computer > Manage. 2. In the Computer Management dialog box, click Services, and Applications > Services. 3. In the Services area, double-click WatClientServiceHost and then click Start. Contact your system administrator. Determine if network is down. If the network is down, a UNIFI client cannot communicate with the workgroup server. If the workgroup server is not down, wait ten minutes and try again to log on to UNIFI October, 2013, Rev. A

83 UNIFI Installation troubleshooting Problem Symptom Solution Cannot log on to UNIFI portal using a client computer. Cannot perform database backup on a workstation. Cannot qualify software. Cannot bring LND online after migrating or upgrading the workgroup server. The error message appears: "Downloading this file from server <IP address> error occurred." Server IQ stops at the 50 % mark and fails to create report. Complete one of these operations: Uninstall and then reinstall UNIFI software on the client, and specify the server's host name, not the IP Address needed to connect to the workgroup server. Modify LAN settings as follows: In Internet Explorer, click Tools > Internet Options. On the Internet Options dialog box, click Connections, and then click LAN settings. On the Local Area Network (LAN) Settings dialog box, clear the check box "Use a proxy server for your LAN". You must be a member of the ORA_DBA group on this workstation to back up the database. If you are installing UNIFI software on an English workstation or workgroup server, you must confirm that your Windows regional settings are configured for English (United States). The symbols for English (United States) use decimal, not comma formatting, which is important when displaying numeric values ("12.56", not "12,56"). To confirm that you have the correct regional settings: 1. From the Windows "Search programs and files" text box, type Regional Settings. 2. In the Region and Language dialog box, ensure "English (United States)" is selected as the format in the Formats tab. You must upgrade UNIFI software on a laboratory network device after you upgrade or migrate the workgroup server. 18 October, 2013, Rev. A 83

84 7 Troubleshooting Problem Symptom Solution Database backup did not run automatically. Cannot view Waters printer. Cannot select the ASM data disk drives during software installation. Windows collapses all devices from the same manufacturer in a single icon. The Waters Internal Print Queue sometimes only appears in Windows Devices and Printers. ASM data disk drives are not enabled on the Oracle ASM drive selection page of the installer. If your workgroup server is located outside the US, you may need to create a database backup schedule tasks in Windows Task Scheduler. Refer to the UNIFI System Administrator's Guide for the procedure to create a database schedule task. In Windows Devices and Printers, right click Waters UNIFI printer to display all Waters' printers. The ASM data disk drives are allocated. They must be online and unallocated. Tip: If a disk is online and has a drive letter assigned to it, right-click on the disk, select Delete Disk, and then Delete Volume. Right-click on the disk and select Delete Partition October, 2013, Rev. A

85 UNIFI Installation troubleshooting Problem Symptom Solution Cannot download UNIFI license activation file from the Waters web site. Cannot download UNIFI license activation file from Waters web site. Windows Internet Explorer version 9 restricts an encrypted file from being downloaded. Windows Internet Explorer version 10 restricts an encrypted file from being downloaded. Turn off the "Do not save encrypted pages to disk" option in the Internet Options dialog box. To turn off this feature, do the following: 1. In IE 9, click Tools (Alt-X) > Internet options. 2. In the Internet Options dialog box, click the Advanced tab. 3. On the Advanced tab, clear the "Do not save encrypted pages to disk" option in the Security section, and then click OK. Turn off the "Do not save encrypted pages to disk" option in the Internet Options dialog box. To turn off this feature, do the following: 1. In IE 10, click Tools (Alt-X) > Internet options. 2. In the Internet Options dialog box, click the Advanced tab. 3. On the Advanced tab, clear the "Do not save encrypted pages to disk" option in the Security section, and then click OK. 4. On the Security tab, select Internet, click Custom level, and then click OK. 5. Scroll down to the Downloads option and then click Enable, and then click OK. 18 October, 2013, Rev. A 85

86 7 Troubleshooting October, 2013, Rev. A

87 A GMP Default Installations Contents: Default settings overview 87 Data folders 89 Global policies 90 Folder policies 94 Roles 96 Predefined reasons 100 Predefined meanings and comments 108 Custom fields 109 User account 109 Event properties 110 Default settings overview When you install UNIFI software, you decide whether you want to configure policy and audit trail settings for a regulated (GxP) or non-regulated environment. If you chose "Configure settings for a regulated environment (GxP)", UNIFI software configures data folders, global policies, folder policies, roles, custom fields, event properties, an administrator user account, and predefined reasons to comply with GxP (Good Practice quality guidelines and regulations). You can change these settings at any time. If you chose "Configure settings for a regulated environment (GxP)", UNIFI software configures these policies and settings. 18 October, 2013, Rev. A 87

88 A GMP Default Installations Default settings for a non-regulated environment: Policy Global policies Folder policies Predefined reasons Roles User accounts Custom fields Description Global policies establish rules for the entire system, such as how to display the time and date in the software. UNIFI software applies the GMP data folder reason policy to the Company (root) data folder. This folder policy defines whether users are required to enter a reason and their passwords when they modify or delete objects such as, analysis injections, processing of analyses, reports, that reside in data folders. If you don't want to apply this policy to all folders, you can revoke it. Reasons explain why users performed an action, such as, modified an analysis method, deleted a data folder, or approved a report. Reasons created in advance save users time because once they are created, users can select an appropriate reason from a list and do not need to create their own reason. Previously created reasons are called "predefined" and ensure that reasons recorded within the event log are consistent. Roles are a set of permissions that control users' ability to perform tasks and functions in the software. Roles are based on users' job functions, such as a chemist or lab technician. Initially, the UNIFI software ships with the system administrator, chemist, analyst, guest, and field service engineer roles, but you can define as many roles to suit your company's needs. UNIFI software is shipped with one default Administrator account. Custom fields track, manage, calculate, and report information about results, samples, extracted report information, and scientific applications. Initially, the UNIFI software ships with custom fields used by qualification, but you can define as many custom fields to suit your company's needs. Event properties trail, and data audit trail view. Each message resides within a category; for The event log stores audit trail messages in the event browser, system audit example, Acquisition, Data Management, and Security and Administration, and contains a severity level and export requirement. Predefined meanings and comments When users review items, such as reports, for approval or rejection, they must provide a "meaning". Comments explain why users approve or reject an item, such as a report or qualification results. Previously created meanings and comments are called "predefined". If you chose "Configure settings for a non-regulated environment (non GxP)", UNIFI software configures these global policies October, 2013, Rev. A

89 Data folders Default global policy settings for non-regulated environment: Policy Settings Description Audit Trail Reasons Timeout User Account No reasons and passwords required. 60 minutes for both inactive work sessions and Signoff dialog box. No password or limit to the number of failed authentication attempts. Qualification No qualification requirements Users do not need to supply a reason and their password when they modify or delete a system object. The number of minutes that a work session can remain inactive before the application closes and users must enter their user names and passwords to log back on to the software. The number of minutes that the Signoff dialog box can remain inactive before it closes. No user account password requirements and no limit to the number of times that users can enter their user name and password incorrectly before their account status is changed from active to disabled. No tasks are required prior to performing a qualification. The data folder policy "Non GxP" is applied to the Company data folder and users do not need to supply a reason and their password when modify or delete objects such as analysis injections and reports that reside in data folders. Data folders Administration > Security > Access Management > Data Folders When you install UNIFI software, the software installs these default data folders: The Company\Templates\Waters English folder contains the default templates and methods shipped with the software. After you install the software, you can import default projects, in the form of.uep files, from the product DVD. 18 October, 2013, Rev. A 89