Page 1 of 9. Protocol: adult_other_adni3basichumanprotocol25x_ _ _1. 3 Plane Localizer. 3 Plane Localizer PATIENT POSITION
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1 3 Localizer FOV 26.0 Slice Thickness 5.0 Slice Spacing 0.0 Freq 256 Phase PLANE 3 Localizer Unswap Phase Correction Gradient Echo Imaging Options Seq, Fast Recon All Images 3 Localizer Pause / SCIC Page 1 of 9
2 Calibration Scan Number of Echoes 1 Calibration Scan 3D SPGR Imaging Options EDR, Fast, ZIP2, Calib FOV 30.0 Slice Thickness 9.4 R/L Phase Correction Calibration Scan Recon All Images Contrast Yes/ Pause / SCIC Page 2 of 9
3 Accelerated Sagittal IR-FSPGR Flip Angle 11 TE TI 400 SAGITTAL Accelerated Sagittal IR- FSPGR Min Full Receiver Bandwidth Pause / SCIC 2 3D SPGR Imaging Options EDR, Fast, IrP, Asset FOV 25.6 Slice Thickness 1.0 Location per Slab 200 Overlap Locations 0 Freq 256 Phase 256 S/I Phase Correction User CV User CV Recon All Images Accelerated Sagittal IR-FSPGR Please do not oblique. Please do not reduce the number of slices. Please do not adjust protocol values. Page 3 of 9
4 Sagittal 3D FLAIR SAGITTAL TE TR TI 1473 Echo Train Length 182 Receiver Bandwidth Fat/Water Saturation Pause / SCIC 2 Sagittal 3D FLAIR Fat 3D Cube T2 FLAIR Imaging Options EDR, Fast, IrP, ARC FOV 25.6 Slice Thickness 1.2 Location per Slab 186 Overlap Locations 0 Freq 256 Phase 256 S/I Phase Correction User CV Recon All Images Sagittal 3D FLAIR Please do not oblique. Please do not reduce the number of slices. Please do not adjust protocol values. Page 4 of 9
5 Axial T2 Star Flip Angle 20 TE 20.0 Number of Echoes 1 TR Receiver Bandwidth Recon All Images Contrast Yes/ Axial T2 Star Gradient Echo Imaging Options FC, EDR FOV 22.0 Slice Thickness 4.0 Slice Spacing 0.0 Freq 256 Phase 192 A/P # of Acq. Before Pause 0 Phase Correction Pause / SCIC 2 Axial T2 Star Please do not oblique. Please do not reduce the number of slices. Please do not adjust protocol values. Page 5 of 9
6 Axial 3D pcasl (Eyes Open) 3D 3DASL Imaging Options EDR, Fast, Spiral FOV 24.0 Slice Thickness 4.0 Axial 3D pcasl (Eyes Open) Receiver Bandwidth Delay after Acquisition without AV Pause / SCIC 0 Tips: -When prescribing the 3D slab, the bottom of the slab should be positioned at the bottom of the cerebellum Freq 512 Phase 8 R/L NEX 3.00 Phase Correction Recon All Images Axial 3D pcasl (Eyes Open) Page 6 of 9
7 TE Axial DTI Minimum TR Number of Shots 1 Spin Echo Imaging Options EPI, DIFF, Asset FOV 23.2 Slice Thickness 2.0 Slice Spacing 0.0 Freq 116 Phase 116 R/L Phase Correction Yes Axial DTI Fat/Water Saturation Pause / SCIC 2 Fat Please do not oblique. Please do not reduce the number of slices. Please do not adjust protocol values. User CV User CV Optimized TE Diffusion Directions Number of Diffusion Directions Number of T2 Images 6 Dual Spin Echo Diffusion Tenser Processing Output Recon All Images Contrast Yes/ Yes Tensor 48 Selection Axial DTI Page 7 of 9
8 Flip Angle 90 TE 30.0 TR Number of Shots 1 Axial rsfmri (Eyes Open) Gradient Echo Imaging Options MPh, EPI FOV 22.0 Slice Thickness 3.4 Slice Spacing 0.0 Freq 64 Phase 64 R/L Phase Correction Yes Axial rsfmri (Eyes Open) Initial State Fat/Water Saturation Pause / SCIC Control Fat *Instruct patient to keep eyes open during this scan and to focus on 1 spot. Cover brain in one acq, ensure slab is positioned from inferior to superior. Must have 48 slices, please do not subtract or add any slices. Do not oblique slices. (Do not change series descritpion) User CV Slice per Location 200 Phase Acquisition Order Delay after Acquisition Delay after Acquisition without AV Recon All Images Contrast Yes/ Minimum 2 Axial rsfmri (Eyes Open) Page 8 of 9
9 HighResHippo Flip Angle 122 TE 50.0 Number of Echoes 1 OBLIQUE TR Echo Train Length 15 Receiver Bandwidth Pause / SCIC 2 HighResHippo FSE-XL Imaging Options Fast, Asset FOV 17.5 Slice Thickness 2.0 Slice Spacing Intleave Freq 448 Phase 448 S/I Fat Shift DIR rmal (I) # of Acq. Before Pause 0 Phase Correction Yes User CV Recon All Images HighResHippo Angle the slices perpendicular to the hippocampul body. Please refer to the study manual for further details. Page 9 of 9
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